| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bruno P Moura, Rogério L Rufino, Ricardo C Faria, Paulo Roberto S Amori. Effects of isotemporal substitution of sedentary behavior with light-intensity or moderate-to-vigorous physical activity on cardiometabolic markers in male adolescents. PloS one. vol 14. issue 11. 2020-03-23. PMID:31770423. |
the isotemporal substitution model was used to assess the effects of replacing different sb bouts (5, 10, 30, and 60 min) with lipa or mvpa on cardiometabolic markers [body mass index, waist circumference, body fat percentage (bf%), total cholesterol, high-density lipoprotein cholesterol (hdl-c), non-hdl-c, low-density lipoprotein cholesterol, triglyceride (tg), glucose, insulin, homeostatic model assessment of insulin resistance (homa2-ir), insulin sensitivity (homa2-s), beta cell function (homa2-β), systolic-blood pressure (sbp), diastolic-blood pressure, and cardiometabolic risk score]. |
2020-03-23 |
2023-08-13 |
human |
| Hiroki Okauchi, Chiaki Hashimoto, Reiko Nakao, Katsutaka Oish. Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice. Chronobiology international. vol 36. issue 1. 2020-03-16. PMID:30212233. |
abbreviations: anova: analysis of variance; df: daytime feeding; ffa: free fatty acid; glp-1: glucagon-like peptide-1; homa-ir: homeostasis model assessment of insulin resistance; neat: non-exercise activity thermogenesis; nf: nighttime feeding; rf: restricted feeding; rw: running-wheel; scn: suprachiasmatic nucleus; se: standard error of the mean; sed: sedentary; spa: spontaneous physical activity; t-cho: total cholesterol; tg: triglyceride; wat: white adipose tissues. |
2020-03-16 |
2023-08-13 |
mouse |
| Ren Lin, Yue Jia, Fengjuan Wu, Yuan Meng, Qi Sun, Lihong Ji. Combined Exposure to Fructose and Bisphenol A Exacerbates Abnormal Lipid Metabolism in Liver of Developmental Male Rats. International journal of environmental research and public health. vol 16. issue 21. 2020-03-16. PMID:31661889. |
serum total cholesterol (t-cho), triglyceride (tg), low, high density lipoprotein cholesterol (ldl-c, hdl-c), blood glucose, insulin, il-17 and tnf-α levels were also measured. |
2020-03-16 |
2023-08-13 |
rat |
| Zoe Petraki, Stavros Droubogiannis, Konstantina Mylonaki, Gregory Chlouverakis, Andreas Plaitakis, Cleanthe Spanak. Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion. Metabolism: clinical and experimental. vol 100. 2020-02-26. PMID:31400387. |
tg animals maintained 2.6-fold higher fasting serum insulin levels (mean ± sd: 1.63 ± 0.15 ng/ml; n = 12) than wt mice (0.63 ± 0.05 ng/ml; n = 12; p < 0.0001). |
2020-02-26 |
2023-08-13 |
mouse |
| Zoe Petraki, Stavros Droubogiannis, Konstantina Mylonaki, Gregory Chlouverakis, Andreas Plaitakis, Cleanthe Spanak. Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion. Metabolism: clinical and experimental. vol 100. 2020-02-26. PMID:31400387. |
induced comparable serum insulin increases in tg and wt mice, suggesting no significant glud2 effect on glucose-stimulated insulin release. |
2020-02-26 |
2023-08-13 |
mouse |
| Zoe Petraki, Stavros Droubogiannis, Konstantina Mylonaki, Gregory Chlouverakis, Andreas Plaitakis, Cleanthe Spanak. Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion. Metabolism: clinical and experimental. vol 100. 2020-02-26. PMID:31400387. |
however, l-leucine had little effect on the high insulin levels of the tg mice, suggesting that, under the high adp levels that prevail in β-cells in the fasting state, glutamate flux through hgdh2 is close to maximal. |
2020-02-26 |
2023-08-13 |
mouse |
| Zoe Petraki, Stavros Droubogiannis, Konstantina Mylonaki, Gregory Chlouverakis, Andreas Plaitakis, Cleanthe Spanak. Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion. Metabolism: clinical and experimental. vol 100. 2020-02-26. PMID:31400387. |
hence, the present data, showing that glud2 expression in tg mice improves in vivo glucose homeostasis by boosting fasting serum insulin levels, suggest that evolutionary adaptation of hgdh2 has enabled humans to achieve narrow-range euglycemia by regulating glutamate-mediated basal insulin secretion. |
2020-02-26 |
2023-08-13 |
mouse |
| Treepradab Norkaew, Janine L Brown, Chatchote Thitaram, Pakkanut Bansiddhi, Chaleamchat Somgird, Veerasak Punyapornwithaya, Khanittha Punturee, Preeyanat Vongchan, Nopphamas Somboon, Jaruwan Khonme. Associations among tourist camp management, high and low tourist seasons, and welfare factors in female Asian elephants in Thailand. PloS one. vol 14. issue 6. 2020-02-18. PMID:31206564. |
we compared twice monthly serum insulin, glucose, fructosamine, total cholesterol (tc), triglyceride (tg), low density lipoprotein (ldl), high density lipoprotein (hdl), and fecal glucocorticoid metabolite (fgm) concentrations to body condition scores (bcs) at five camps with different management styles (e.g., tourist activities, work type, diet) between the high (november-february) and low (march-october) tourist seasons. |
2020-02-18 |
2023-08-13 |
Not clear |
| Treepradab Norkaew, Janine L Brown, Chatchote Thitaram, Pakkanut Bansiddhi, Chaleamchat Somgird, Veerasak Punyapornwithaya, Khanittha Punturee, Preeyanat Vongchan, Nopphamas Somboon, Jaruwan Khonme. Associations among tourist camp management, high and low tourist seasons, and welfare factors in female Asian elephants in Thailand. PloS one. vol 14. issue 6. 2020-02-18. PMID:31206564. |
by contrast, positive associations were found between tourist number and bcs, tg, and insulin, perhaps related to tourists feeding elephants. |
2020-02-18 |
2023-08-13 |
Not clear |
| Bruno P Moura, Rogério L Rufino, Ricardo C Faria, Jeffer E Sasaki, Paulo Roberto S Amori. Can Replacing Sitting Time with Standing Time Improve Adolescents' Cardiometabolic Health? International journal of environmental research and public health. vol 16. issue 17. 2020-02-14. PMID:31461890. |
an isotemporal substitution approach was used to examine the effects of replacing different periods of sit (15, 30, 60, and 120 min) with sta on cardiometabolic biomarkers [total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), non-hdl-c, low-density lipoprotein cholesterol (ldl-c), triglycerides (tg), glucose, insulin, homa2-β, homa2-s, and homa2-ir]. |
2020-02-14 |
2023-08-13 |
Not clear |
| Tao Liang, Xiaohui Xu, Dongmei Ye, Wenxia Chen, Biyun Gao, Yanjun Huan. Caspase/AIF/apoptosis pathway: a new target of puerarin for diabetes mellitus therapy. Molecular biology reports. vol 46. issue 5. 2020-02-12. PMID:31228042. |
the results showed that pr decreased the serum fasting blood glucose (fbg), total cholesterol (tc), triglyceride (tg) and low-density lipoprotein (ldl) levels but significantly increased the fasting blood insulin (fins) and high-density lipoprotein (hdl) levels. |
2020-02-12 |
2023-08-13 |
mouse |
| Anna Stefanska, Paulina Cembrowska, Justyna Kubacka, Magdalena Kuligowska-Prusinska, Grazyna Sypniewsk. Gonadotropins and Their Association with the Risk of Prediabetes and Type 2 Diabetes in Middle-Aged Postmenopausal Women. Disease markers. vol 2019. 2020-02-10. PMID:31467615. |
serum/plasma was assayed for glucose, hdl-c, tg, c-reactive protein (crp), 17beta-estradiol, estrone, insulin, thyroid-stimulating hormone (tsh), fsh, and lh. |
2020-02-10 |
2023-08-13 |
Not clear |
| Nana Jin, Yu Wang, Lin Liu, Feng Xue, Tingbo Jiang, Mingzhu X. Dysregulation of the Renin-Angiotensin System and Cardiometabolic Status in Mice Fed a Long-Term High-Fat Diet. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-10. PMID:31523052. |
serum biomarkers were measured, including total cholesterol (tc), triglyceride (tg), insulin, glycated hemoglobin (hba1c), brain natriuretic peptide (bnp), renin, angiotensin-converting enzyme (ace), angiotensin ii (ang-ii), ang-ii type 1 receptor (at₁r), and aldosterone. |
2020-02-10 |
2023-08-13 |
mouse |
| Nana Jin, Yu Wang, Lin Liu, Feng Xue, Tingbo Jiang, Mingzhu X. Dysregulation of the Renin-Angiotensin System and Cardiometabolic Status in Mice Fed a Long-Term High-Fat Diet. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-10. PMID:31523052. |
results compared with nd, hfd resulted in increased blood glucose, body weight, tc, tg, hba1c, insulin, and bnp and levels of serum ace, ang-ii, aldosterone, at₁r, cardiomyocyte csa, and interstitial collagen in the myocardium compared. |
2020-02-10 |
2023-08-13 |
mouse |
| Xiaoqing Huang, Wenfan Chen, Changsheng Yan, Renzhi Yang, Qiongyun Chen, Hongzhi Xu, Yuanpeng Huan. Gypenosides improve the intestinal microbiota of non-alcoholic fatty liver in mice and alleviate its progression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 118. 2020-02-04. PMID:31545283. |
it is shown that gp administration reduced body weight, enhanced the sensitivity to insulin resistance (ir) and decreased serum levels of alt, ast and tg in nafld mice. |
2020-02-04 |
2023-08-13 |
mouse |
| Sobia Rana, Ayesha Sultana, Adil Anwar Bhatt. Association of Journal of biosciences. vol 44. issue 4. 2020-01-30. PMID:31502573. |
fasting high-density lipoprotein cholesterol (hdl-c) and homeostatic model assessment of insulin sensitivity showed a significantly lower mean whereas body mass index (bmi), waist circumference, systolic blood pressure (sbp), diastolic blood pressure (dbp), fasting blood glucose, insulin, total cholesterol (tc), low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol, triglycerides (tg), cholesterol to hdl-c ratio, tg to hdl-c ratio, homeostatic model assessment of insulin resistance, visceral adiposity index, lipid accumulation product and the product of tg and glucose showed a significantly higher mean in the presence of mets. |
2020-01-30 |
2023-08-13 |
human |
| Kayleigh M Beaudry, Michaela C Devrie. Sex-based differences in hepatic and skeletal muscle triglyceride storage and metabolism Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 44. issue 8. 2020-01-24. PMID:30702924. |
similarly, elevated skeletal muscle tg, termed intramyocellular lipids (imcl), are related to insulin resistance in obesity and type ii diabetes. |
2020-01-24 |
2023-08-13 |
Not clear |
| Eman G Behiry, Nazih Mohamed El Nady, Omima M AbdEl Haie, May Kamel Mattar, Amira Magd. Evaluation of TG-HDL Ratio Instead of HOMA Ratio as Insulin Resistance Marker in Overweight and Children with Obesity. Endocrine, metabolic & immune disorders drug targets. vol 19. issue 5. 2020-01-21. PMID:30663576. |
triglyceride (tg) and hdl-c on the other hand is a routine test and inexpensive compared to insulin. |
2020-01-21 |
2023-08-13 |
Not clear |
| Feng Dong, Longhao Wang, Chengbin Wan. Thrombin Generation in Chinese Pregnant Women and the Effect of Insulin Use on Thrombin Generation in Patients with GDM. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. vol 25. 2020-01-09. PMID:31311294. |
calibrated automated thrombogram (cat) is a test to monitor the thrombin generation (tg), a laboratory marker of thrombosis risk, and increases during normal pregnancy, but it is still unclear whether tg is related to the use of insulin in pregnant women with gestational diabetes mellitus (gdm). |
2020-01-09 |
2023-08-13 |
cat |
| Yang Xin Zi Xu, Geetika Bassi, Suresh Mishr. Prohibitin: a prime candidate for a pleiotropic effector that mediates sex differences in obesity, insulin resistance, and metabolic dysregulation. Biology of sex differences. vol 10. issue 1. 2020-01-06. PMID:31118075. |
transgenic (tg) mouse models overexpressing phb (phb-tg) and a phospho-mutant phb (mphb-tg) from the fatty acid binding protein-4 (fabp-4) gene promoter display sex-neutral obesity; however, obesity-related insulin resistance and metabolic dysregulation are male-specific. |
2020-01-06 |
2023-08-13 |
mouse |