| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Laws, G M Reave. Evidence for an independent relationship between insulin resistance and fasting plasma HDL-cholesterol, triglyceride and insulin concentrations. Journal of internal medicine. vol 231. issue 1. 1992-02-27. PMID:1732395. |
elevated plasma insulin and triglyceride (tg) and decreased high-density-lipoprotein (hdl)-cholesterol concentrations have been shown to be risk factors for coronary heart disease (chd). |
1992-02-27 |
2023-08-11 |
Not clear |
| A Laws, G M Reave. Evidence for an independent relationship between insulin resistance and fasting plasma HDL-cholesterol, triglyceride and insulin concentrations. Journal of internal medicine. vol 231. issue 1. 1992-02-27. PMID:1732395. |
the high group had significantly higher fasting (p less than 0.05) and post-oral glucose challenge (p less than 0.01) insulin concentrations, higher fasting tg (p less than 0.05) and lower fasting hdl-cholesterol (p less than 0.05) concentrations than the other two groups. |
1992-02-27 |
2023-08-11 |
Not clear |
| A Laws, G M Reave. Evidence for an independent relationship between insulin resistance and fasting plasma HDL-cholesterol, triglyceride and insulin concentrations. Journal of internal medicine. vol 231. issue 1. 1992-02-27. PMID:1732395. |
the data suggest that insulin resistance has an effect on the modulation of plasma insulin, tg and hdl-cholesterol concentrations, independent of generalized, abdominal or physical endurance capacity. |
1992-02-27 |
2023-08-11 |
Not clear |
| G R Gavino, V C Gavin. Modulation of polyunsaturated fatty acid content of triglycerides in rat pre-adipocytes in culture. Lipids. vol 26. issue 9. 1992-02-13. PMID:1762515. |
rat peri-renal and epididymal pre-adipocytes in culture undergoing triglyceride (tg) accumulation were incubated with oleic (18:1), linoleic (18:2), alpha-linolenic (18:3 omega 3), arachidonic (20:4) and 4,7,10,13,16,19-docosahexaenoic (22:6 omega 3) acids in the presence of 0.8 microm insulin. |
1992-02-13 |
2023-08-11 |
rat |
| Y D Chen, R Skowronski, A M Coulston, J Pietarinen, C B Hollenbeck, G M Reave. Effect of acute variations in dietary fat and carbohydrate intake on retinyl ester content of intestinally derived lipoproteins. The Journal of clinical endocrinology and metabolism. vol 74. issue 1. 1992-01-30. PMID:1727825. |
the vitamin a and test meals were given at noon (4 h after a standard breakfast), and blood was obtained hourly from noon to midnight for measurement of plasma glucose, insulin, triglyceride (tg), and cholesterol concentrations; concentrations of tg and cholesterol in sverdberg floatation (sf) unit above 400 and sf 20-400 lipoproteins; retinyl ester concentration in plasma; and both sf more than 400 and sf 20-400 lipoproteins. |
1992-01-30 |
2023-08-11 |
Not clear |
| T Watanab. [Diurnal changes in postheparin lipolytic activity (PHLA) and the role of PHLA in triglyceride catabolism in young and middle-aged obese individuals]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 28. issue 5. 1992-01-30. PMID:1753427. |
serum tg and insulin were significantly higher in the obese individuals than normal-weight individuals of both groups. |
1992-01-30 |
2023-08-11 |
human |
| T Watanab. [Diurnal changes in postheparin lipolytic activity (PHLA) and the role of PHLA in triglyceride catabolism in young and middle-aged obese individuals]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 28. issue 5. 1992-01-30. PMID:1753427. |
in the obese individuals in both groups, a positive correlation was demonstrated between serum tg and insulin. |
1992-01-30 |
2023-08-11 |
human |
| C B Hollenbeck, P Johnston, B B Varasteh, Y D Chen, G M Reave. Effects of metformin on glucose, insulin and lipid metabolism in patients with mild hypertriglyceridaemia and non-insulin dependent diabetes by glucose tolerance test criteria. Diabete & metabolisme. vol 17. issue 5. 1992-01-24. PMID:1752350. |
thus, metformin administration to individuals with niddm, who did not have significant fasting hyperglycaemia, led to a decrease in plasma glucose, insulin, ffa, and tg concentration, and an increase in plasma hdl-cholesterol concentration. |
1992-01-24 |
2023-08-11 |
Not clear |
| P Ferrari, D Giachino, P Weidmann, S Shaw, W Riesen, N Neuner, U Keller, G Heyne. Unaltered insulin sensitivity during calcium channel blockade with amlodipine. European journal of clinical pharmacology. vol 41. issue 2. 1992-01-15. PMID:1835931. |
to evaluate the effects of calcium channel blokkade on si, glucose homoeostasis and lipid profiles, studies were made of si (determined by the minimal model method of bergman), basal glucose and insulin levels, serum total triglyceride (tg) and lipoprotein cholesterol (c) fractions and certain other variables in 38 healthy young men (24 y) during placebo and after 3 weeks of calcium channel blockade with amlodipine 5 mg once daily. |
1992-01-15 |
2023-08-11 |
Not clear |
| P Ferrari, D Giachino, P Weidmann, S Shaw, W Riesen, N Neuner, U Keller, G Heyne. Unaltered insulin sensitivity during calcium channel blockade with amlodipine. European journal of clinical pharmacology. vol 41. issue 2. 1992-01-15. PMID:1835931. |
heart rate, body weight and 24 h urinary sodium excretion were unaltered, and so were fasting plasma glucose (placebo vs amlodipine: 4.86 vs 4.83 mmol.l-1, respectively) and insulin levels (7.7 vs 7.9 microu.ml-1), si (10.5 vs 9.6.10(-4) x min-1 pro microu.ml-1), serum total tg, c and lipoprotein c fractions. |
1992-01-15 |
2023-08-11 |
Not clear |
| T Hirano, J C Mamo, H Takeuchi, S Nagano, T Takahash. Correlation of insulin deficiency and hypertriglyceridemia in diabetic rats. Diabetes research and clinical practice. vol 12. issue 3. 1991-10-15. PMID:1889346. |
the relationship between plasma insulin (iri) and lipid concentration, or triglyceride (tg) kinetics was studied in streptozotocin-induced diabetic rats (dm) to examine how insulin deficiency is associated with the mechanism of hypertriglyceridemia (htg) in diabetes. |
1991-10-15 |
2023-08-11 |
rat |
| D C Shen, M M Fuh, S M Shieh, Y D Chen, G M Reave. Effect of gemfibrozil treatment in sulfonylurea-treated patients with noninsulin-dependent diabetes mellitus. The Journal of clinical endocrinology and metabolism. vol 73. issue 3. 1991-09-24. PMID:1874929. |
measurements were made of mean hourly plasma glucose, insulin, tg, and ffa concentrations from 1200-1600 h in response to a test meal; hepatic glucose production (hgp); insulin-stimulated glucose uptake during a hyperinsulinemic glucose clamp study (mcr); and fasting plasma lipoprotein tg and cholesterol concentrations in 12 patients with niddm before and 3 months after gemfibrozil treatment. |
1991-09-24 |
2023-08-11 |
Not clear |
| D C Shen, M M Fuh, S M Shieh, Y D Chen, G M Reave. Effect of gemfibrozil treatment in sulfonylurea-treated patients with noninsulin-dependent diabetes mellitus. The Journal of clinical endocrinology and metabolism. vol 73. issue 3. 1991-09-24. PMID:1874929. |
although ambient plasma tg and ffa concentrations fell significantly, plasma glucose, insulin, hgp, concentrations fell significantly, plasma glucose, insulin, hgp, and glucose mcr did not change. |
1991-09-24 |
2023-08-11 |
Not clear |
| D C Shen, M M Fuh, S M Shieh, Y D Chen, G M Reave. Effect of gemfibrozil treatment in sulfonylurea-treated patients with noninsulin-dependent diabetes mellitus. The Journal of clinical endocrinology and metabolism. vol 73. issue 3. 1991-09-24. PMID:1874929. |
patients in fair control had significant decreases in mean hourly plasma concentrations of glucose (15.1 +/- 1.7 to 12.6 +/- 0.9 mmol/l; p less than 0.001), insulin (523 +/- 59 to 471 +/- 75 pmol/l; p less than 0.001), ffa (652 +/- 150 to 504 +/- 76 mumol/l), and hgp (9.5 0.4 to 8.1 +/- 0.4 mumol/kg.min; p less than 0.005), and an increase in glucose mcr (2.63 +/- 0.49 to 3.72 +/- 0.54 ml/kg.min; p less than 0.07) in association with a fall in tg from 6.9 +/- 1.3 to 3.5 +/- 0.9 mmol/l (p less than 0.001). |
1991-09-24 |
2023-08-11 |
Not clear |
| D C Shen, M M Fuh, S M Shieh, Y D Chen, G M Reave. Effect of gemfibrozil treatment in sulfonylurea-treated patients with noninsulin-dependent diabetes mellitus. The Journal of clinical endocrinology and metabolism. vol 73. issue 3. 1991-09-24. PMID:1874929. |
despite a significant fall in mean hourly tg concentration (4.6 +/- 0.7 to 3.8 +/- 0.7 mmol/l; p less than 0.001), neither insulin, ffa, hgp, nor glucose mcr changed in patients in good control. |
1991-09-24 |
2023-08-11 |
Not clear |
| O Isozaki, T Tsushima, N Emoto, M Saji, Y Tsuchiya, H Demura, Y Sato, K Shizume, S Kimura, L D Koh. Methimazole regulation of thyroglobulin biosynthesis and gene transcription in rat FRTL-5 thyroid cells. Endocrinology. vol 128. issue 6. 1991-07-02. PMID:1645261. |
the effect is evident under conditions in which the ability of insulin or insulin-like growth factor-i to increase tg mrna levels is already maximal. |
1991-07-02 |
2023-08-11 |
rat |
| J F Hopp, W K Palme. Effect of glucose and insulin on triacylglycerol metabolism in isolated normal and diabetic skeletal muscle. Metabolism: clinical and experimental. vol 40. issue 3. 1991-04-11. PMID:2000033. |
the effects of insulin and glucose on triacylglycerol (tg) metabolism in normal and diabetic isolated skeletal muscle were investigated in this study. |
1991-04-11 |
2023-08-11 |
Not clear |
| J F Hopp, W K Palme. Effect of glucose and insulin on triacylglycerol metabolism in isolated normal and diabetic skeletal muscle. Metabolism: clinical and experimental. vol 40. issue 3. 1991-04-11. PMID:2000033. |
in the absence of insulin and glucose, normal and diabetic skeletal muscle tg content and synthesis were decreased. |
1991-04-11 |
2023-08-11 |
Not clear |
| J F Hopp, W K Palme. Effect of glucose and insulin on triacylglycerol metabolism in isolated normal and diabetic skeletal muscle. Metabolism: clinical and experimental. vol 40. issue 3. 1991-04-11. PMID:2000033. |
in contrast, in the presence of insulin and glucose, the normal and diabetic tg contents were unchanged and triacylglycerol synthesis was increased as compared with the respective control values. |
1991-04-11 |
2023-08-11 |
Not clear |
| J F Hopp, W K Palme. Effect of glucose and insulin on triacylglycerol metabolism in isolated normal and diabetic skeletal muscle. Metabolism: clinical and experimental. vol 40. issue 3. 1991-04-11. PMID:2000033. |
however, insulin and glucose increased intramuscular tg content to a greater extent than could be accounted for by their stimulation of tg synthesis, indicating that insulin and glucose appear to inhibit tg hydrolysis in diabetic muscle, as well as in normal muscle. |
1991-04-11 |
2023-08-11 |
Not clear |