| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tzyy-Nan Huang, Yi-Ping Hsue. Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders. Frontiers in neuroscience. vol 9. 2015-11-20. PMID:26578866. |
previous studies of tbr1 (-∕-) mice have indicated critical roles for tbr1 in the development of the cerebral cortex, amygdala, and olfactory bulb. |
2015-11-20 |
2023-08-13 |
mouse |
| Héctor R Méndez-Gómez, Eva Vergaño-Vera, José L Abad, Alessandro Bulfone, Rosario Moratalla, Flora de Pablo, Carlos Vicario-Abejó. The T-box brain 1 (Tbr1) transcription factor inhibits astrocyte formation in the olfactory bulb and regulates neural stem cell fate. Molecular and cellular neurosciences. vol 46. issue 1. 2011-07-05. PMID:20807572. |
the t-box brain 1 (tbr1) gene encodes a transcription factor necessary for the maintenance and/or differentiation of glutamatergic cells in the olfactory bulb (ob) and cortex, although its precise function in the development of glutamatergic neurons is not known. |
2011-07-05 |
2023-08-12 |
mouse |
| George Hadjivassiliou, Lillian Martinian, Waney Squier, Ingmar Blumcke, Eleonora Aronica, Sanjay M Sisodiya, Maria Tho. The application of cortical layer markers in the evaluation of cortical dysplasias in epilepsy. Acta neuropathologica. vol 120. issue 4. 2010-12-03. PMID:20411268. |
laminar expression patterns in normal cortex were observed with tbr1, map1b, n200 and otx1. |
2010-12-03 |
2023-08-12 |
Not clear |
| Francesco Bedogni, Rebecca D Hodge, Gina E Elsen, Branden R Nelson, Ray A M Daza, Richard P Beyer, Theo K Bammler, John L R Rubenstein, Robert F Hevne. Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 29. 2010-09-01. PMID:20615956. |
conversely, genes that implement caudal cortex and layer 5 identity, such as bhlhb5 and fezf2, were up-regulated in tbr1 mutants. |
2010-09-01 |
2023-08-12 |
mouse |
| Nicole Büttner, Steven A Johnsen, Sebastian Kügler, Tanja Voge. Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 15. 2010-05-14. PMID:20348416. |
af9/mllt3 interferes with tbr1 expression through epigenetic modification of histone h3k79 during development of the cerebral cortex. |
2010-05-14 |
2023-08-12 |
mouse |
| Nadhim Bayatti, Subrot Sarma, Christopher Shaw, Janet A Eyre, Demetrius A Vouyiouklis, Susan Lindsay, Gavin J Clowr. Progressive loss of PAX6, TBR2, NEUROD and TBR1 mRNA gradients correlates with translocation of EMX2 to the cortical plate during human cortical development. The European journal of neuroscience. vol 28. issue 8. 2009-01-26. PMID:18973570. |
in this study, using in situ hybridization, we analysed the expression of emx2, pax6, tbr2, neurod and tbr1 mrna in the developing human cortex between 8 and 12 postconceptional weeks (pcw). |
2009-01-26 |
2023-08-12 |
human |
| Robert F Hevner, Emily Miyashita-Lin, John L R Rubenstei. Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other. The Journal of comparative neurology. vol 447. issue 1. 2002-06-26. PMID:11967891. |
to test this hypothesis, the development of corticothalamic and thalamocortical connections was studied in mice with mutations of transcription factor genes expressed specifically in the cortex (tbr1), the dorsal thalamus (gbx2), or both (pax6). |
2002-06-26 |
2023-08-12 |
mouse |
| Robert F Hevner, Emily Miyashita-Lin, John L R Rubenstei. Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other. The Journal of comparative neurology. vol 447. issue 1. 2002-06-26. PMID:11967891. |
surprisingly, thalamic axons (which do not express tbr1) deviated into the external capsule and amygdala regions, without entering the cortex. |
2002-06-26 |
2023-08-12 |
mouse |