| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Burgos-Ramos, A Hervás-Aguilar, L Puebla-Jiménez, M C Boyano-Adánez, E Arilla-Ferreir. Chronic but not acute intracerebroventricular administration of amyloid beta-peptide(25-35) decreases somatostatin content, adenylate cyclase activity, somatostatin-induced inhibition of adenylate cyclase activity, and adenylate cyclase I levels in the rat hippocampus. Journal of neuroscience research. vol 85. issue 2. 2007-03-29. PMID:17086550. |
chronic but not acute intracerebroventricular administration of amyloid beta-peptide(25-35) decreases somatostatin content, adenylate cyclase activity, somatostatin-induced inhibition of adenylate cyclase activity, and adenylate cyclase i levels in the rat hippocampus. |
2007-03-29 |
2023-08-12 |
rat |
| Duk-Soo Kim, Sung-Eun Kwak, Ji-Eun Kim, Jin-Sang Kim, Moo Ho Won, Tae-Cheon Kan. The selective effects of somatostatin- and GABA-mediated transmissions on voltage gated Ca2+ channel immunoreactivity in the gerbil hippocampus. Brain research. vol 1115. issue 1. 2006-12-04. PMID:16920080. |
to identify whether altered expressions of voltage gated ca(2+) channel (vgcc) are linked to inhibitory transmission abnormalities in the gerbil hippocampus, we investigated the effects of gaba receptor or somatostatin receptor (sst) antagonists/agonists on vgcc immunoreactivity in vivo. |
2006-12-04 |
2023-08-12 |
Not clear |
| Eun Young Shim, Hee Jung Kim, Myung-Jun Kim, Duck-Joo Rhie, Yang-Hyeok Jo, Myung-Suk Kim, Sang June Hahn, Mun-Yong Lee, Shin Hee Yoo. Desensitization of somatostatin-induced inhibition of low extracellular magnesium concentration-induced calcium spikes in cultured rat hippocampal neurons. Brain research. vol 1111. issue 1. 2006-11-24. PMID:16879804. |
we tested the effects of prolonged exposure to somatostatin on 0.1 mm extracellular mg(2+) concentration ([mg(2+)](o))-induced intracellular free ca(2+) concentration ([ca(2+)](i)) spikes in cultured rat hippocampal neurons using fura-2-based microfluorimetry. |
2006-11-24 |
2023-08-12 |
rat |
| Eun Young Shim, Hee Jung Kim, Myung-Jun Kim, Duck-Joo Rhie, Yang-Hyeok Jo, Myung-Suk Kim, Sang June Hahn, Mun-Yong Lee, Shin Hee Yoo. Desensitization of somatostatin-induced inhibition of low extracellular magnesium concentration-induced calcium spikes in cultured rat hippocampal neurons. Brain research. vol 1111. issue 1. 2006-11-24. PMID:16879804. |
these results indicate that the prolonged activation of somatostatin receptors induces the desensitization of somatostatin-induced inhibition on low [mg(2+)](o)-induced [ca(2+)](i) spikes through the activation of grk2 and partly a novel pkcepsilon in cultured rat hippocampal neurons. |
2006-11-24 |
2023-08-12 |
rat |
| Kyriaki Thermos, Paola Bagnoli, Jacques Epelbaum, Daniel Hoye. The somatostatin sst1 receptor: an autoreceptor for somatostatin in brain and retina? Pharmacology & therapeutics. vol 110. issue 3. 2006-11-13. PMID:16274747. |
in at least the latter 3 structures, the sst1 receptor appears to act as an inhibitory autoreceptor located on somatostatin neurons, whereas in the hippocampus such a role is still based on circumstantial evidence. |
2006-11-13 |
2023-08-12 |
mouse |
| Maurizio Cammalleri, Davide Cervia, Massimo Dal Monte, Davide Martini, Daniel Langenegger, Dominique Fehlmann, Dominik Feuerbach, Barbara Pavan, Daniel Hoyer, Paola Bagnol. Compensatory changes in the hippocampus of somatostatin knockout mice: upregulation of somatostatin receptor 2 and its function in the control of bursting activity and synaptic transmission. The European journal of neuroscience. vol 23. issue 9. 2006-10-06. PMID:16706848. |
compensatory changes in the hippocampus of somatostatin knockout mice: upregulation of somatostatin receptor 2 and its function in the control of bursting activity and synaptic transmission. |
2006-10-06 |
2023-08-12 |
mouse |
| A M Hernández-Pinto, L Puebla-Jiménez, E Arilla-Ferreir. A vitamin A-free diet results in impairment of the rat hippocampal somatostatinergic system. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16757122. |
it is also well known that the tetradecapeptide somatostatin binds to specific receptors in the hippocampus and, when injected into this brain area, facilitates the acquisition of spatial tasks. |
2006-10-04 |
2023-08-12 |
rat |
| A M Hernández-Pinto, L Puebla-Jiménez, E Arilla-Ferreir. A vitamin A-free diet results in impairment of the rat hippocampal somatostatinergic system. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16757122. |
rats fed a vitamin a-free diet exhibited a significant reduction of somatostatin-like immunoreactivity content in the hippocampus whereas the somatostatin mrna levels were unaltered. |
2006-10-04 |
2023-08-12 |
rat |
| Kenichi Tokita, Tatsuo Inoue, Shunji Yamazaki, Feng Wang, Takayuki Yamaji, Nobuya Matsuoka, Seitaro Muto. FK962, a novel enhancer of somatostatin release, exerts cognitive-enhancing actions in rats. European journal of pharmacology. vol 527. issue 1-3. 2006-02-08. PMID:16325809. |
fk962 (10(-9) - 10(- 6) m) significantly enhanced high k+-evoked somatostatin release from rat hippocampal slices. |
2006-02-08 |
2023-08-12 |
rat |
| Melanie K Tallent, Véronique Fabre, Cuie Qiu, Marta Calbet, Tyra Lamp, Michael V Baratta, Chisa Suzuki, Coree L Levy, George R Siggins, Steven J Henriksen, José R Criado, Amanda Roberts, Luis de Lece. Cortistatin overexpression in transgenic mice produces deficits in synaptic plasticity and learning. Molecular and cellular neurosciences. vol 30. issue 3. 2006-01-05. PMID:16182561. |
cortistatin-14 (cst) is a neuropeptide expressed in cortical and hippocampal interneurons that shares 11 of 14 residues with somatostatin. |
2006-01-05 |
2023-08-12 |
mouse |
| Katrin Boels, Irm Hermans-Borgmeyer, H Chica Schalle. Identification of a mouse orthologue of the G-protein-coupled receptor SALPR and its expression in adult mouse brain and during development. Brain research. Developmental brain research. vol 152. issue 2. 2005-11-08. PMID:15351514. |
the mouse orthologue of somatostatin and angiotensin-like peptide receptor (salpr) was amplified from cdna of the hippocampal cell line ht22. |
2005-11-08 |
2023-08-12 |
mouse |
| Marie-Hélène Bassant, Axelle Simon, Frédérique Poindessous-Jazat, Zsolt Csaba, Jacques Epelbaum, Pascal Dournau. Medial septal GABAergic neurons express the somatostatin sst2A receptor: functional consequences on unit firing and hippocampal theta. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 8. 2005-10-26. PMID:15728843. |
medial septal gabaergic neurons express the somatostatin sst2a receptor: functional consequences on unit firing and hippocampal theta. |
2005-10-26 |
2023-08-12 |
rat |
| Avron D Spier, Véronique Fabre, Luis de Lece. Cortistatin radioligand binding in wild-type and somatostatin receptor-deficient mouse brain. Regulatory peptides. vol 124. issue 1-3. 2005-10-06. PMID:15544857. |
in somatostatin receptor subtype-2 knock-out (ko) mice, autoradiographic iodinated somatostatin-14 binding was observed in the hippocampus and habenula but was removed in the cortex and amygdaloid nuclei, specific iodinated cortistatin-14 binding sites were found in the hippocampus, habenula and throughout the cortex. |
2005-10-06 |
2023-08-12 |
mouse |
| Kathie L Eagleson, Alexandre Bonnin, Pat Levit. Region- and age-specific deficits in gamma-aminobutyric acidergic neuron development in the telencephalon of the uPAR(-/-) mouse. The Journal of comparative neurology. vol 489. issue 4. 2005-09-27. PMID:16025458. |
among the other forebrain regions examined, only the adult hippocampus shows a loss of gabaergic interneurons, although the somatostatin, rather than the parvalbumin, subpopulation contributes to this loss. |
2005-09-27 |
2023-08-12 |
mouse |
| Xin-sheng Cao, Xi-qing Sun, Yan-hong Wu, Xing-yu Wu, Ting-song Liu, Shu Zhan. Changes of hippocampus somatostatin and learning ability in rats after +Gz exposure. Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering. vol 18. issue 2. 2005-08-08. PMID:15977382. |
changes of hippocampus somatostatin and learning ability in rats after +gz exposure. |
2005-08-08 |
2023-08-12 |
rat |
| Takashi Saito, Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Jiro Takano, Shu-Ming Huang, Takahiro Suemoto, Makoto Higuchi, Takaomi C Said. Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation. Nature medicine. vol 11. issue 4. 2005-06-30. PMID:15778722. |
a genetic deficiency of somatostatin altered hippocampal neprilysin activity and localization, and increased the quantity of a hydrophobic 42-mer form of abeta, abeta(42), in a manner similar to presenilin gene mutations that cause familial alzheimer disease. |
2005-06-30 |
2023-08-12 |
Not clear |
| Anna Pittaluga, Marco Feligioni, Fabio Longordo, Marica Arvigo, Maurizio Raiter. Somatostatin-induced activation and up-regulation of N-methyl-D-aspartate receptor function: mediation through calmodulin-dependent protein kinase II, phospholipase C, protein kinase C, and tyrosine kinase in hippocampal noradrenergic nerve endings. The Journal of pharmacology and experimental therapeutics. vol 313. issue 1. 2005-05-19. PMID:15608072. |
somatostatin receptors and glutamate n-methyl-d-aspartate (nmda) receptors coexist on hippocampal noradrenergic axon terminals. |
2005-05-19 |
2023-08-12 |
rat |
| Alena Savonenko, Guilian M Xu, Tatiana Melnikova, Johanna L Morton, Victoria Gonzales, Molly P F Wong, Donald L Price, Fai Tang, Alicja L Markowska, David R Borchel. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiology of disease. vol 18. issue 3. 2005-05-17. PMID:15755686. |
in the 18-month-old cohorts, amyloid burdens were much higher in appswe/ps1de9 mice with statistically significant but mild decreases in cholinergic markers (cortex and hippocampus) and somatostatin levels (cortex). |
2005-05-17 |
2023-08-12 |
mouse |
| Maurizio Cammalleri, Davide Cervia, Daniel Langenegger, Yanqiang Liu, Massimo Dal Monte, Daniel Hoyer, Paola Bagnol. Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548214. |
somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices. |
2005-03-01 |
2023-08-12 |
mouse |
| Halina Baran, Berthold Kepplinger, Markus Draxler, Gerhard Skofitsc. Choline acetyltransferase, glutamic acid decarboxylase and somatostatin in the kainic acid model for chronic temporal lobe epilepsy. Neuro-Signals. vol 13. issue 6. 2005-02-15. PMID:15627816. |
the somatostatin level was significantly increased in all cortical regions (between 162 and 221% of control) as well as in the hippocampus (119% of control), but reduced in the amygdala/piriform cortex (45% of control; p<0.01). |
2005-02-15 |
2023-08-12 |
Not clear |