| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X Xu, Z Hawi, K J Brookes, R Anney, M Bellgrove, B Franke, E Barry, W Chen, J Kuntsi, T Banaschewski, J Buitelaar, R Ebstein, M Fitzgerald, A Miranda, R D Oades, H Roeyers, A Rothenberger, J Sergeant, E Sonuga-Barke, H-C Steinhausen, S V Faraone, M Gill, P Asherso. Replication of a rare protective allele in the noradrenaline transporter gene and ADHD. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 8. 2009-01-06. PMID:18937296. |
in a previous study screening 51 candidate genes for association with adhd in a multi-centre european sample (the image project), two single nucleotide polymorphisms (snps) within the norepinephrine transporter (slc6a2) gene were found to be associated with attention deficit hyperactivity disorder (adhd). |
2009-01-06 |
2023-08-12 |
Not clear |
| Sayaka Arata, Niwako Ogata, Michito Shimozuru, Yukari Takeuchi, Yuji Mor. Sequences and polymorphisms of the canine monoamine transporter genes SLC6A2, SLC6A3, and SLC6A4 among five dog breeds. The Journal of veterinary medical science. vol 70. issue 9. 2008-12-08. PMID:18840973. |
they include transporters for norepinephrine, dopamine and serotonin, which are encoded by the slc6a2, slc6a3, and slc6a4 genes, respectivily. |
2008-12-08 |
2023-08-12 |
dog |
| Emi Yamano, Tokiko Isowa, Yoshiro Nakano, Fumihiko Matsuda, Tomoko Hashimoto-Tamaoki, Hideki Ohira, Shinji Kosug. Association study between reward dependence temperament and a polymorphism in the phenylethanolamine N-methyltransferase gene in a Japanese female population. Comprehensive psychiatry. vol 49. issue 5. 2008-10-30. PMID:18702937. |
based on this theory, we examined the correlation between reward dependence (rd) trait, measured with the temperament and character inventory, and 5 polymorphisms in genes of norepinephrine pathways, adrb1, comt, pnmt, slc18a1, and slc6a2, in 85 japanese female nursing students. |
2008-10-30 |
2023-08-12 |
human |
| Soo-Churl Cho, Jae-Won Kim, Boong-Nyun Kim, Jun-Won Hwang, Mira Park, Soon Ae Kim, Dae-Yeon Cho, Hee-Jeong Yoo, Un-Sun Chung, Jung-Woo Son, Tae-Won Par. No evidence of an association between norepinephrine transporter gene polymorphisms and attention deficit hyperactivity disorder: a family-based and case-control association study in a Korean sample. Neuropsychobiology. vol 57. issue 3. 2008-09-15. PMID:18552510. |
previous studies have demonstrated that the norepinephrine transporter gene (slc6a2) is associated with adhd. |
2008-09-15 |
2023-08-12 |
Not clear |
| M K Hahn, J U Blackford, K Haman, M Mazei-Robison, B A English, H C Prasad, A Steele, L Hazelwood, H M Fentress, R Myers, R D Blakely, E Sanders-Bush, R Shelto. Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression. Genes, brain, and behavior. vol 7. issue 4. 2008-06-25. PMID:18081710. |
mpt analyses show significant associations of the norepinephrine transporter (net, slc6a2) -182 t/c (rs2242446) with recurrent depression [odds ratio, or = 4.15 (1.91-9.02)], net -3081 a/t (rs28386840) with increase in appetite [or = 3.58 (1.53-8.39)] and the presynaptic choline transporter (cht, slc5a7) ile89val (rs1013940) with ham-d-17 total score {i.e. |
2008-06-25 |
2023-08-12 |
Not clear |
| W Retz, M Rösler, C Kissling, S Wiemann, R Hünnerkopf, A Coogan, J Thome, C Freita. Norepinephrine transporter and catecholamine-O-methyltransferase gene variants and attention-deficit/hyperactivity disorder symptoms in adults. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 2. 2008-05-30. PMID:17994190. |
in this study, we investigated the association of several adhd symptom scores (german short form of the wender utah rating scale, wurs-k; adhd self report, adhd-sb, and the german validated version of the wraadds, wri) with haplotypes of the catechol-o-methyltransferase (comt) and the norepinephrine transporter (slc6a2) genes. |
2008-05-30 |
2023-08-12 |
human |
| J Sandra Kooij, A Marije Boonstra, Sita H Vermeulen, Angelien G Heister, Huibert Burger, Jan K Buitelaar, Barbara Frank. Response to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1). American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 2. 2008-05-07. PMID:17955457. |
in this pharmacogenetic study in adults with adhd (n = 42), a stratified analysis was performed of the association between response to methylphenidate (mph), assessed under double-blind conditions, and polymorphisms in the genes encoding the dopamine transporter, slc6a3 (dat1), the norepinephrine transporter, slc6a2 (net), and the dopamine receptor d4, drd4. |
2008-05-07 |
2023-08-12 |
Not clear |
| Andrea Dlugos, Christine Freitag, Christa Hohoff, Jennifer McDonald, Edwin H Cook, Jürgen Deckert, Harriet de Wi. Norepinephrine transporter gene variation modulates acute response to D-amphetamine. Biological psychiatry. vol 61. issue 11. 2007-07-10. PMID:17239355. |
because the effects of amphetamine are mediated in part by the norepinephrine transporter (slc6a2), we examined interindividual differences in mood response to amphetamine in relation to slc6a2 gene polymorphisms. |
2007-07-10 |
2023-08-12 |
Not clear |
| Z Lin, B K Madra. Human genetics and pharmacology of neurotransmitter transporters. Handbook of experimental pharmacology. issue 175. 2007-05-23. PMID:16722243. |
genetic studies of human biogenic amine transporter genes, including the dopamine transporter (hdat; slc6a3), the serotonin transporter (hsert; slc6a4), and the norepinephrine transporter (hnet; slc6a2) have provided insight into how genomic variations in these transporter genes influence pharmacology and brain physiology. |
2007-05-23 |
2023-08-12 |
human |
| Chun-Hyung Kim, Maureen K Hahn, Yoosook Joung, Susan L Anderson, Angela H Steele, Michelle S Mazei-Robinson, Ian Gizer, Martin H Teicher, Bruce M Cohen, David Robertson, Irwin D Waldman, Randy D Blakely, Kwang-Soo Ki. A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 50. 2007-01-22. PMID:17146058. |
in this study, we report a previously uncharacterized and common a/t polymorphism at -3081 upstream of the transcription initiation site of the human norepinephrine transporter gene [solute carrier family 6, member 2 (slc6a2)]. |
2007-01-22 |
2023-08-12 |
human |
| Christopher A Rippel, Andrew J Kobets, Dustin Y Yoon, Phillip N Williams, Yin Yao Shugart, Dana D Bridges, David J Vandenbergh, Harvey S Singe. Norepinephrine transporter polymorphisms in Tourette syndrome with and without attention deficit hyperactivity disorder: no evidence for significant association. Psychiatric genetics. vol 16. issue 5. 2006-12-11. PMID:16969268. |
patients with tourette syndrome with (n=115) and without (n=110) attention-deficit hyperactivity disorder were evaluated for association with two single nucleotide polymorphisms of the norepinephrine transporter gene (slc6a2); a t-182c single nucleotide polymorphism located in the 5' flanking promoter region and a silent mutation (g1287a) occurring in exon 9. |
2006-12-11 |
2023-08-12 |
Not clear |
| Inna Belfer, Gabriel Phillips, Julie Taubman, Heather Hipp, Robert H Lipsky, Mary-Anne Enoch, Mitchell B Max, David Goldma. Haplotype architecture of the norepinephrine transporter gene SLC6A2 in four populations. Journal of human genetics. vol 49. issue 5. 2004-10-21. PMID:15362567. |
haplotype architecture of the norepinephrine transporter gene slc6a2 in four populations. |
2004-10-21 |
2023-08-12 |
Not clear |
| Koh Ono, Yoshitaka Iwanaga, Toshifumi Mannami, Yoshihiro Kokubo, Hitonobu Tomoike, Kazuo Komamura, Keisuke Shioji, Naomi Yasui, Naomi Tago, Naoharu Iwa. Epidemiological evidence of an association between SLC6A2 gene polymorphism and hypertension. Hypertension research : official journal of the Japanese Society of Hypertension. vol 26. issue 9. 2004-06-24. PMID:14620922. |
this study was designed to examine the relation of genetic variants of the norepinephrine transporter gene (solute carrier family 6, member 2; slc6a2) with hypertension in a japanese population. |
2004-06-24 |
2023-08-12 |
human |
| Ruth E Urwin, Bruce H Bennetts, Bridget Wilcken, Pierre J V Beumont, Janice D Russell, Kenneth P Nun. Investigation of epistasis between the serotonin transporter and norepinephrine transporter genes in anorexia nervosa. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 7. 2003-09-02. PMID:12784104. |
we then performed the first reported investigation of epistasis between the sert gene and norepinephrine transporter gene (slc6a2, alias net) in an, as an earlier study suggested that atypical an responds to the dual serotonin-norepinephrine reuptake inhibitor venlafaxine. |
2003-09-02 |
2023-08-12 |
Not clear |
| Maureen K Hahn, David Robertson, Randy D Blakel. A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 11. 2003-07-01. PMID:12805287. |
a mutation in the human norepinephrine transporter gene (slc6a2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters. |
2003-07-01 |
2023-08-12 |
human |
| H Iwasa, M Kurabayashi, R Nagai, Y Nakamura, T Tanak. Genetic variations in five genes involved in the excitement of cardiomyocytes. Journal of human genetics. vol 46. issue 9. 2001-12-04. PMID:11558906. |
we provide here 29 genetic variations, including 28 novel ones, in five genes that are potentially involved in the excitement of cardiomyocytes: we found 4 in kcna10, 2 in kcnk1, 8 in kcnk6, 11 in slc18a1 (vmat1), and 4 in slc6a2 (norepinephrine transporter). |
2001-12-04 |
2023-08-12 |
Not clear |