| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Milewich, C E Shaw, K M Doody, W E Rainey, J I Mason, B R Car. 3 beta-Hydroxysteroid dehydrogenase activity in glandular and extraglandular human fetal tissues. The Journal of clinical endocrinology and metabolism. vol 73. issue 5. 1991-12-02. PMID:1834689. |
the kinetic isotope effect introduced by substitution of tritium for hydrogen at the c-3 alpha position of dhea, determined with six different tissues, was 2.5 +/- 0.7 (mean +/- sd). |
1991-12-02 |
2023-08-11 |
human |
| K Morishige, H Kurachi, K Amemiya, H Adachi, M Inoue, A Miyake, O Tanizawa, Y Sakoyam. Involvement of transforming growth factor alpha/epidermal growth factor receptor autocrine growth mechanism in an ovarian cancer cell line in vitro. Cancer research. vol 51. issue 21. 1991-11-25. PMID:1718591. |
as much as 1.12 +/- 0.14 ng (sd; n = 3)/10(7) cells/24 h of tgf alpha was secreted in the conditioned media. |
1991-11-25 |
2023-08-11 |
human |
| Y Iino, N Sugamata, S Owada, T Tago, H Sato, T Yokoe, M Maemura, Y Morishita, R Horiuch. Antitumor effects of a nonsteroidal aromatase inhibitor (CGS 16949A) on 7, 12-dimethylbenz[alpha]anthracene-induced mammary tumors in rats. Japanese journal of clinical oncology. vol 21. issue 3. 1991-11-25. PMID:1834875. |
the effects of a nonsteroidal aromatase inhibitor, cgs 16949a, on female sprague-dawley (sd) rats with 7, 12-dimethylbenz[alpha]anthracene (dmba)-induced mammary cancers were examined in relation to estrogen receptors (er). |
1991-11-25 |
2023-08-11 |
rat |
| Y Y Yang, E K Yeh, S S Chang, H C Deng, C F Le. Maintenance lithium levels could be lowered: based on Taiwanese and Danish studies. Journal of the Formosan Medical Association = Taiwan yi zhi. vol 90. issue 5. 1991-11-08. PMID:1680992. |
the pharmacokinetic parameters were as follows: k12 (microconstant) = 0.3455 +/- 0.5345 (mean +/- sd) h-1; k21 (microconstant) = 0.1691 +/- 0.1242 h-1; k10 (microconstant) = 0.1320 +/- 0.1112 h-1; vl (volume of distribution of central compartment) = 16.9057 +/- 5.9384 1; vss (volume of distribution at steady state) = 38.8917 +/- 11.4540 1; v-beta (volume of distribution of elimination phase) = 46.3809 +/- 13.8742 1; alpha (distribution rate constant) = 0.5932 +/- 0.7090; and beta (excretion rate constant) = 0.0361 +/- 0.0141. |
1991-11-08 |
2023-08-11 |
Not clear |
| A Jörres, D Jörres, G M Gahl, M Kessel, C Müller, E Köttgen, S Serke, E Schulz, A Mahiou. Leukotriene B4 and tumor necrosis factor release from leukocytes: effect of peritoneal dialysate. Nephron. vol 58. issue 3. 1991-10-24. PMID:1654527. |
mnc incubated in buffer and lps produced (mean +/- sd) 1,006 +/- 522 pg tnf alpha/5 x 10(6) cells; no significant amounts of tnf alpha were detectable in the presence of dialysate. |
1991-10-24 |
2023-08-11 |
Not clear |
| B Gay, H Towbin, C Schnell, K Einsle, P Graf, D Gyga. Direct chemiluminescence immunoassay (CLIA) for muramyl tripeptide phosphatidyl-ethanolamine in plasma. Journal of bioluminescence and chemiluminescence. vol 6. issue 2. 1991-09-27. PMID:1882709. |
half-life time was 0.37 h +/- 0.03 (mean +/- sd, alpha phase) and 1.76 h +/- 0.08 (mean +/- sd, beta phase), clearance and volume of distribution were 0.09 +/- 0.02 l/h x kg (mean +/- sd) and 0.06 +/- 0.01 l/kg (mean +/- sd) respectively. |
1991-09-27 |
2023-08-11 |
rat |
| G Chalevelakis, S Karaoulis, A G Yalouris, T Economopoulos, N Tountas, S Rapti. Globin chain synthesis in myelodysplastic syndromes. Journal of clinical pathology. vol 44. issue 2. 1991-09-09. PMID:1864985. |
the mean (sd) value of the total alpha:beta ratio was 0.82 (0.45) ranging from 0.05 to 1.73. |
1991-09-09 |
2023-08-11 |
Not clear |
| H S Jafari, X Sáez-Llorens, E Grimprel, J C Argyle, K D Olsen, G H McCracke. Characteristics of experimental Candida albicans infection of the central nervous system in rabbits. The Journal of infectious diseases. vol 164. issue 2. 1991-08-23. PMID:1856486. |
in recipients of 10(5) and 10(3) cfu/ml inocula, the mean +/- sd peak cerebrospinal fluid (csf) tumor necrosis factor-alpha (tnf alpha) concentrations were 1.6 +/- 2.42 and 0.3 +/- 0.59 ng/ml, respectively, at 6 h; the mean +/- sd csf leukocyte and protein concentrations were 6291 +/- 6515 and 453 +/- 674 cells/mm3 (at 24 h) and 118 +/- 90 and 109 +/- 122 mg/dl (at 12 and 24 h), respectively. |
1991-08-23 |
2023-08-11 |
Not clear |
| Y Iino, M Yoshida, T Tago, S Owada, N Sugamata, R Horiuch. Effects of sequential and combined immuno-endocrine therapies using OK-432 (Picibanil) and tamoxifen on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma. Japanese journal of clinical oncology. vol 21. issue 1. 1991-08-15. PMID:1906118. |
effects of sequential and combined immuno-endocrine therapies using ok-432 (picibanil) and tamoxifen (tam) on the growth of 7,12-dimethylbenz [alpha] anthracene (dmba)-induced carcinoma were examined in 128 female sprague-dawley (sd) rats. |
1991-08-15 |
2023-08-11 |
rat |
| C K Castle, M E Pape, K R Marotti, G W Melchio. Secretion of pre-beta-migrating apoA-I by cynomolgus monkey hepatocytes in culture. Journal of lipid research. vol 32. issue 3. 1991-08-12. PMID:1906086. |
one had an apparent molecular mass greater than 1 million da, migrated pre-beta, and accounted for 11 +/- 3 (mean +/- sd)% of the total; one had an apparent molecular mass of 104 kda, had alpha migration, and accounted for 27 +/- 2% of the total; and one had an apparent molecular mass of 50 kda, migrated pre-beta, and accounted for 46 +/- 9% of the total. |
1991-08-12 |
2023-08-11 |
monkey |
| P Vajro, A Fontanella, A De Vincenzo, P Lettera, L Greco, A Coppa, M D'Armient. Monitoring of serum alpha-fetoprotein levels in children with chronic hepatitis B virus infection. Journal of pediatric gastroenterology and nutrition. vol 12. issue 1. 1991-08-02. PMID:1712035. |
serum alpha fp levels in controls were found to be always lower than 5 ng/ml (0.1-4.4 ng/ml, mean +/- sd of 1.34 +/- 1.32 ng/ml). |
1991-08-02 |
2023-08-11 |
Not clear |
| P Minuz, C Lechi, E Arosio, P Guzzo, M Zannoni, C Lauciello, A Lech. Effect of picotamide on platelet aggregation and on thromboxane A2 production in vivo. Thrombosis and haemostasis. vol 65. issue 3. 1991-07-17. PMID:2048055. |
though ex vivo platelet txa2 production (txb2 concentration after arachidonic-acid-induced aggregation) was reduced from 946 +/- 141 (mean +/- sd) to 285 +/- 91 ng/ml in controls and from 1515 +/- 673 to 732 +/- 420 ng/ml in patients with arteriopathy, there was no effect on urinary excretion of 2,3-dinor-txb2 (in vivo indicator of platelet txa2 production), or on in vivo pgi2 production (urinary excretion of 6-keto-pgf1 alpha and 2,3-dinor-6-keto-pgf1 alpha). |
1991-07-17 |
2023-08-11 |
human |
| D A Galbraith, P T Boag, H L Gibbs, B N Whit. Sizing bands on autoradiograms: a study of precision for scoring DNA fingerprints. Electrophoresis. vol 12. issue 2-3. 1991-07-11. PMID:1674911. |
we suggest that the distance between bands be at least 2.8 standard deviations (sd) before they are declared different at alpha = 0.05, and 3.7 sd for alpha = 0.01. |
1991-07-11 |
2023-08-11 |
Not clear |
| J W Mouton, A M Horrevorts, P G Mulder, E P Prens, M F Miche. Pharmacokinetics of ceftazidime in serum and suction blister fluid during continuous and intermittent infusions in healthy volunteers. Antimicrobial agents and chemotherapy. vol 34. issue 12. 1991-05-20. PMID:2088186. |
the half-life at alpha phase (t1/2 alpha) was 9.6 min (sd, 4.6), t1/2 beta was 94.8 min (sd, 5.4), area under the concentration-time curve (auc) was 285.4 micrograms.h/ml (sd, 22.7), total body clearance was 0.115 liter/h.kg (sd, 0.022), and volume of distribution at steady state was 0.178 liter/kg (sd, 0.023). |
1991-05-20 |
2023-08-11 |
human |
| P E Jablonski, J G Ferr. Purification and properties of methyl coenzyme M methylreductase from acetate-grown Methanosarcina thermophila. Journal of bacteriology. vol 173. issue 8. 1991-05-14. PMID:2013570. |
denaturing polyacrylamide gel electrophoresis revealed three protein bands corresponding to molecular weights of 69,000 (sd, 1,200), 42,000 (sd, 1,200), and 33,000 (sd, 1,200) and indicated a subunit configuration of alpha 1 beta 1 gamma 1. |
1991-05-14 |
2023-08-11 |
Not clear |
| M Barral-Netto, R Badaró, A Barral, R P Almeida, S B Santos, F Badaró, D Pedral-Sampaio, E M Carvalho, E Falcoff, R Falcof. Tumor necrosis factor (cachectin) in human visceral leishmaniasis. The Journal of infectious diseases. vol 163. issue 4. 1991-05-06. PMID:1901333. |
high tumor necrosis factor-alpha (tnf alpha) levels were present in the serum of 24 of 28 active visceral leishmaniasis (vl) patients (142.9 +/- 113.9 pg/ml, mean +/- sd), whereas levels were not elevated in 26 of 30 patients with cryptic leishmanial infection (16 asymptomatic, 4 with self-healing subclinical infection, and 10 posttreatment vl cases). |
1991-05-06 |
2023-08-11 |
human |
| N Usui, E G Mimnaugh, B K Sinh. A role for the interleukin 1 receptor in the synergistic antitumor effects of human interleukin 1 alpha and etoposide against human melanoma cells. Cancer research. vol 51. issue 3. 1991-02-28. PMID:1824825. |
surface il-1 alpha receptors on both a375-c6 and a375-c5 cells were measured using 125i-radiolabeled ril-1 alpha binding; a375-c6 cells had 701 +/- 128 (sd) receptor molecules/cell and a375-c5 cells only had 58 +/- 33 receptor molecules/cell. |
1991-02-28 |
2023-08-11 |
human |
| I Weiss, F E Cash, M B Coleman, A Pressley, J G Adams, T Sanguansermsri, S A Liebhaber, M H Steinber. Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood. vol 76. issue 12. 1991-02-14. PMID:2265255. |
the nature of the thalassemic defect associated with the alpha sd mutation has been investigated by structural and functional studies. |
1991-02-14 |
2023-08-11 |
mouse |
| I Weiss, F E Cash, M B Coleman, A Pressley, J G Adams, T Sanguansermsri, S A Liebhaber, M H Steinber. Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood. vol 76. issue 12. 1991-02-14. PMID:2265255. |
although in vitro translation of a synthetic alpha 2sd-globin mrna generated levels of alpha globin equivalent to alpha 2a-globin mrna at early time points, the ratio of alpha sd to alpha a globin decreased markedly at later time points. |
1991-02-14 |
2023-08-11 |
mouse |
| I Weiss, F E Cash, M B Coleman, A Pressley, J G Adams, T Sanguansermsri, S A Liebhaber, M H Steinber. Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood. vol 76. issue 12. 1991-02-14. PMID:2265255. |
these data suggest that the thalassemic defect associated with the suan-dok mutation results from a significant instability of the alpha sd globin. |
1991-02-14 |
2023-08-11 |
mouse |