Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D C Underwood, S Bochnowicz, R R Osborn, C S Louden, T K Hart, E H Ohlstein, D W Ha. Chronic hypoxia-induced cardiopulmonary changes in three rat strains: inhibition by the endothelin receptor antagonist SB 217242. Journal of cardiovascular pharmacology. vol 31 Suppl 1. 1998-07-17. PMID:9595510. |
right ventricular hypertrophy (rvh), expressed as the ratio of right free wall/left wall + septum weight, in sd, w, and has was increased by 24, 53, and 48%, respectively, at 7 days, and by 51, 93, and 55% at 14 days compared to normoxic littermates. |
1998-07-17 |
2023-08-12 |
rat |
C Peiró, J Angulo, J L Llergo, L Rodríguez-Mañas, J Marín, C F Sánchez-Ferre. Angiotensin II mediates cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism. Biochemical and biophysical research communications. vol 240. issue 2. 1997-12-23. PMID:9388483. |
we have reported that cultured vascular smooth muscle cells (vsmc) from hypertensive ren-2 transgenic rats (tgr) are constitutively hypertrophic when compared to matched cells from normotensive sprague-dawley rats (sd), by a mechanism involving the endogenous production of angiotensin ii (aii). |
1997-12-23 |
2023-08-12 |
rat |
C Peiró, J L Llergo, J Angulo, J M López-Novoa, A Rodríguez-López, L Rodríguez-Mañas, C F Sánchez-Ferre. Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats. British journal of pharmacology. vol 121. issue 7. 1997-09-29. PMID:9257925. |
under serum-free conditions, vsmc from hypertensive tgr were hypertrophic when compared to sd vsmc, as they presented a higher protein content per cell (335 +/-18 and 288 +/- 7 pg per cell respectively; p<0.05) and increased mean planar cell surface area, as determined by image analysis (4,074 +/- 238 and 4,764 +/- 204 microm2, respectively; p < 0.05). |
1997-09-29 |
2023-08-12 |
rat |
C Peiró, J L Llergo, J Angulo, J M López-Novoa, A Rodríguez-López, L Rodríguez-Mañas, C F Sánchez-Ferre. Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats. British journal of pharmacology. vol 121. issue 7. 1997-09-29. PMID:9257925. |
we concluded that cultured vsmc from tgr are hypertrophic in comparison with those from sd. |
1997-09-29 |
2023-08-12 |
rat |
F S Dhabhar, B S McEwen, R L Spence. Adaptation to prolonged or repeated stress--comparison between rat strains showing intrinsic differences in reactivity to acute stress. Neuroendocrinology. vol 65. issue 5. 1997-07-07. PMID:9158068. |
strain differences in hpa axis responsivity are also reflected in the significant adrenal hypertrophy observed in f344 rats (but not in sd or lew rats) following repeated stress. |
1997-07-07 |
2023-08-12 |
rat |
H Romppanen, M Marttila, J Magga, O Vuolteenaho, P Kinnunen, I Szokodi, H Ruskoah. Adrenomedullin gene expression in the rat heart is stimulated by acute pressure overload: blunted effect in experimental hypertension. Endocrinology. vol 138. issue 6. 1997-06-17. PMID:9165059. |
short-term cardiac overload, induced by administration of angiotensin ii (33.3 microg/kg/h, s.c., osmotic minipumps) for two weeks in normotensive sd rats resulted in left ventricular hypertrophy (3.05 +/- 0.17 vs. 2.75 +/- 0.3 mg/g, p<0.05) and a 1.5-fold increase (p<0.05) in ventricular adm mrna levels. |
1997-06-17 |
2023-08-12 |
human |
V Di Bello, R Pedrinelli, D Giorgi, A Bertini, L Talarico, M T Caputo, B Massimiliano, G Dell'Omo, M Paterni, C Giust. Ultrasonic videodensitometric analysis of two different models of left ventricular hypertrophy. Athlete's heart and hypertension. Hypertension (Dallas, Tex. : 1979). vol 29. issue 4. 1997-04-29. PMID:9095080. |
we compared male essential hypertensive subjects who had marked cardiac hypertrophy (left ventricular mass index adjusted for height > 2 sd of mean of control group) (group 1) with normotensive elite veteran athletes who had comparable cardiac hypertrophy (group 2) and sedentary normotensive subjects as controls (group 3). |
1997-04-29 |
2023-08-12 |
human |
E L Schiffrin, R Lariviere, J S Li, P Sventek, R M Touy. Endothelin-1 gene expression and vascular hypertrophy in DOCA-salt hypertension compared to spontaneously hypertensive rats. Clinical and experimental pharmacology & physiology. Supplement. vol 22. issue 1. 1997-03-25. PMID:9072349. |
in this study, the effects of salt, doca and the development of hypertension in doca-salt hypertensive rats on the expression of the endothelin-1 gene in blood vessels and on vascular hypertrophy were compared in sprague-dawley (sd) rats and spontaneously hypertensive rats (shr). |
1997-03-25 |
2023-08-12 |
rat |
C D Reimers, B Schlotter, B M Eicke, T N Wit. Calf enlargement in neuromuscular diseases: a quantitative ultrasound study in 350 patients and review of the literature. Journal of the neurological sciences. vol 143. issue 1-2. 1997-03-20. PMID:8981297. |
absolute calf hypertrophy was diagnosed if the combined thickness of the gastrocnemius and soleus muscles exceeded the mean value of the control persons by at least 3.0 standard deviations (sd). |
1997-03-20 |
2023-08-12 |
Not clear |
C D Reimers, B Schlotter, B M Eicke, T N Wit. Calf enlargement in neuromuscular diseases: a quantitative ultrasound study in 350 patients and review of the literature. Journal of the neurological sciences. vol 143. issue 1-2. 1997-03-20. PMID:8981297. |
relative calf hypertrophy was diagnosed when the ratio of the combined thicknesses of the gastrocnemius and soleus muscles divided by the combined thicknesses of the rectus femoris and vastus intermedius muscles lay at least 3.0 sd below the mean value of the controls. |
1997-03-20 |
2023-08-12 |
Not clear |
P Ruel, J L Hanouz, B Riou, Y Lecarpentier, P Coria. Myocardial effects of eltanolone in hamsters with hypertrophic cardiomyopathy. British journal of anaesthesia. vol 77. issue 5. 1997-01-02. PMID:8957984. |
cardiac hypertrophy (mean 134 (sd 9)%, p < 0.001) was observed in cardiomyopathic hamsters. |
1997-01-02 |
2023-08-12 |
Not clear |
G Dirami, K J Teerds, B A Cook. Effect of a dopamine agonist on the development of Leydig cell hyperplasia in Sprague-Dawley rats. Toxicology and applied pharmacology. vol 141. issue 1. 1996-12-23. PMID:8917689. |
these findings suggest that chronic treatment of male sd rats with the dopamine agonist causes hypertrophy of leydig cells within 5 weeks (as assessed by [3h]methionine incorporation), followed by hyperplasia within 2 years, prior to the development of leydig cell adenomas, which occur within 1-2 years after the initiation of treatment. |
1996-12-23 |
2023-08-12 |
rat |
A M Cotterill, W J McKenna, A F Brady, M Sharland, M Elsawi, M Yamada, C Camacho-Hübner, C J Kelnar, D B Dunger, M A Patton, M O Savag. The short-term effects of growth hormone therapy on height velocity and cardiac ventricular wall thickness in children with Noonan's syndrome. The Journal of clinical endocrinology and metabolism. vol 81. issue 6. 1996-12-11. PMID:8964866. |
in conclusion, rhgh was effective in 24 of the treated patients; these subjects achieved a significant increase in height sd score and hv over 1 yr. abnormal anabolic effects of rhgh on myocardial thickness were not confirmed, and no patient developed features of hypertrophic cardiomyopathy. |
1996-12-11 |
2023-08-12 |
human |
F Alfons. [Cardiomyopathies. VIII. Sudden death in hypertrophic cardiomyopathy]. Revista espanola de cardiologia. vol 49. issue 4. 1996-07-23. PMID:8650406. |
the natural history of patients with hypertrophic cardiomyopathy (hcm) may be shadowed by the appearance of sudden death (sd). |
1996-07-23 |
2023-08-12 |
Not clear |
K Kaizu, Q Y Ling, K Uriu, M Ikeda, O Hashimoto, N Komine, S Et. The characteristics of renal hemodynamics in diabetic spontaneously hypertensive rats in comparison with diabetic Wistar-Kyoto rats. Journal of diabetes and its complications. vol 9. issue 4. 1996-03-13. PMID:8573732. |
diabetic sprague-dawley (sd) rats are known to exhibit renal hyperfiltration and hyperperfusion accompanied by renal hypertrophy. |
1996-03-13 |
2023-08-12 |
rat |
B F Hurley, R A Redmond, R E Pratley, M S Treuth, M A Rogers, A P Goldber. Effects of strength training on muscle hypertrophy and muscle cell disruption in older men. International journal of sports medicine. vol 16. issue 6. 1995-12-15. PMID:7591389. |
to determine whether a total body, heavy resistance, strength training (st) program can significantly increase muscle strength and hypertrophy without muscle cell disruption and soreness in older men, 35 sedentary male subjects between the ages of 50 and 69 years of age (60 +/- 5, mean +/- sd) were studied. |
1995-12-15 |
2023-08-12 |
human |
D Piovan, R Padrini, G Svalato Moreolo, G Magnolfi, O Milanesi, R Zordan, P A Pellegrino, M Ferrar. Verapamil and norverapamil plasma levels in infants and children during chronic oral treatment. Therapeutic drug monitoring. vol 17. issue 1. 1995-05-25. PMID:7725379. |
verapamil and norverapamil trough plasma levels were measured in 22 children, aged from 15 days to 17 years, under chronic oral treatment with the drug (mean daily dose +/- sd: 4.9 +/- 1.4 mg/kg) for supraventricular tachyarrhythmias (n = 20) or hypertrophic cardiomyopathy (n = 2). |
1995-05-25 |
2023-08-12 |
Not clear |
E Lazzeroni, E Picano, C Dodi, L Morozzi, G P Chiriatti, C Lu, G Bott. Dipyridamole echocardiography for diagnosis of coexistent coronary artery disease in hypertrophic cardiomyopathy. Echo-Persantine International Cooperative (EPIC) Study Group--Subproject Hypertrophic Cardiomyopathy. The American journal of cardiology. vol 75. issue 12. 1995-05-18. PMID:7717285. |
to establish the feasibility, safety, and diagnostic accuracy of dipyridamole-stress echocardiography in patients with hypertrophic cardiomyopathy, we performed high-dose dipyridamole testing (up to 0.84 mg/kg over 10 minutes) in 88 patients with hypertrophic cardiomyopathy (63 men; mean age +/- sd, 46 +/- 17 years). |
1995-05-18 |
2023-08-12 |
Not clear |
C Veyrat, D Sainte Beuve, W el Yafi, G Sebaoun, D Kalmanso. A new Doppler imaging measurement in aortic stenosis: the contour length of the jet origin flow area. Relationships between both, with usual Doppler data and left ventricular hypertrophy. Ultrasound in medicine & biology. vol 20. issue 9. 1995-04-11. PMID:7886843. |
mean values (sd) of data were: areas: (planimetry) 1.00 +/- 0.53 cm2, (continuity equation) 0.91 +/- 0.42 cm2, contours: 5.6 +/- 1.6 cm, c/a: 0.66 +/- 0.25, maximal and mean pressure gradients: 68 +/- 34 and 37 +/- 21 mmhg, left ventricular hypertrophy: 138 +/- 30 g/m2 bsa (vs. 100 +/- 18 in normals). |
1995-04-11 |
2023-08-12 |
Not clear |
S Laurent, X Girerd, J J Mourad, P Lacolley, L Beck, P Boutouyrie, J P Mignot, M Safa. Elastic modulus of the radial artery wall material is not increased in patients with essential hypertension. Arteriosclerosis and thrombosis : a journal of vascular biology. vol 14. issue 7. 1994-08-03. PMID:8018679. |
to determine whether this increase was due to hypertension-related hypertrophy of the arterial wall, radial artery functional and geometric parameters from 22 nts (mean +/- sd, 44 +/- 11 years) were compared with those from 25 age- and sex-matched never-treated essential hts (48 +/- 12 years) by using a high-precision ultrasonic, echo-tracking system coupled to a photoplethysmograph (finapres system), which allows simultaneous arterial internal diameter, intima-media thickness, and finger blood pressure measurements. |
1994-08-03 |
2023-08-12 |
human |