| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinwei Cheng, Bin Cheng, Rui Jin, Hongkun Zheng, Jia Zhou, Shengzhou Sha. The role of circulating metabolites and gut microbiome in hypertrophic scar: a two-sample Mendelian randomization study. Archives of dermatological research. vol 316. issue 6. 2024-06-01. PMID:38822918. |
based on the genome-wide significance level, genetically predicted uridine (p = 0.015, odds ratio [or] = 1903.514, 95% confidence interval [ci] 4.280-846,616.433) and isovalerylcarnitine (p = 0.039, or = 7.765, 95% ci 1.106-54.512) were positively correlated with hypertrophic scar risk, while n-acetylalanine (p = 0.013, or = 7.98e-10, 95% ci 5.19e-17-0.012) and glycochenodeoxycholate (p = 0.021, or = 0.021 95% ci 0.003-0.628) were negatively correlated. |
2024-06-01 |
2024-06-03 |
Not clear |
| Xinwei Cheng, Bin Cheng, Rui Jin, Hongkun Zheng, Jia Zhou, Shengzhou Sha. The role of circulating metabolites and gut microbiome in hypertrophic scar: a two-sample Mendelian randomization study. Archives of dermatological research. vol 316. issue 6. 2024-06-01. PMID:38822918. |
circulating metabolites and gut microbiome components may have either positive or negative causal effects on hypertrophic scar formation. |
2024-06-01 |
2024-06-03 |
Not clear |
| Yi Zhang, Xiu Li, Qian Yu, Xiaoyan Lv, Chen Li, Lianzhao Wang, Yue Liu, Qian Wang, Zhigang Yang, Xin Fu, Ran Xia. Using network pharmacology to discover potential drugs for hypertrophic scars. The British journal of dermatology. 2024-05-31. PMID:38820210. |
hypertrophic scar is a disease of abnormal skin fibrosis caused by excessive fibroblast proliferation, and existing drugs cannot achieve satisfactory therapeutic effects. |
2024-05-31 |
2024-06-02 |
Not clear |
| Andrzej Dmytrzak, Klaudyna Lewandowska, Agnieszka Boroń, Beata Łoniewska, Natalie Grzesch, Andrzej Brodkiewicz, Jeremy S C Clark, Andrzej Ciechanowicz, Dorota Kostrzewa-Nowa. No Association of Polymorphisms in the Genes Encoding Interleukin-6 and Interleukin-6 Receptor Subunit Alpha with the Risk of Keloids in Polish Patients. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791322. |
a keloid is a benign fibroproliferative hypertrophy of scar tissue that extends outside the original wound and invades adjacent healthy skin. |
2024-05-25 |
2024-05-27 |
Not clear |
| Rei Ogaw. Update on Hypertrophic Scar Management in Burn Patients. Clinics in plastic surgery. vol 51. issue 3. 2024-05-24. PMID:38789144. |
update on hypertrophic scar management in burn patients. |
2024-05-24 |
2024-05-27 |
Not clear |
| Rei Ogaw. Update on Hypertrophic Scar Management in Burn Patients. Clinics in plastic surgery. vol 51. issue 3. 2024-05-24. PMID:38789144. |
if conservative treatments are not effective and the hypertrophic scar transitions to scar contracture, surgical methods such as z-plasty, full-thickness skin grafting, and local flaps are often used. |
2024-05-24 |
2024-05-27 |
Not clear |
| Yan Li, Yujie Xiao, Yage Shang, Chaolei Xu, Chao Han, Dahai Hu, Juntao Han, Hongtao Wan. Exosomes derived from adipose tissue-derived stem cells alleviated H Cell biology and toxicology. vol 40. issue 1. 2024-05-24. PMID:38789630. |
exosomes derived from adipose tissue-derived stem cells alleviated h hypertrophic scar (hs) is characterized by excessive collagen deposition and myofibroblasts activation. |
2024-05-24 |
2024-05-27 |
Not clear |
| Ramon L Zapata-Sirvent, Ludwik K Branski, Jong O Le. Global Surgery: Burn Outreach by Shriners Children's Texas. Seminars in plastic surgery. vol 38. issue 2. 2024-05-16. PMID:38746704. |
survivors of severe burns may face devastating sequelae due to burn scar contractures and hypertrophic burn scars that may limit the social reintegration. |
2024-05-16 |
2024-05-27 |
Not clear |
| Chin-Ho Wong, Michael Ku Hung Hsie. Medial Epicanthoplasty with the Skin Re-Draping Technique: Technical Refinements for Predictable outcomes. Plastic and reconstructive surgery. 2024-05-14. PMID:38742871. |
this is particularly problematic in asian patients with greater tendencies for hypertrophic scarring and scar hypo or hyper-pigmentation (9). |
2024-05-14 |
2024-05-27 |
Not clear |
| Qinying Yan, Shulin Shen, Linxiao Liu, Jiaqi Weng, Gensuo Zheng, Xu Dong, Jing Yang, Qingliang Yang, Jing Xi. Fabrication of controlled porous and ultrafast dissolution porous microneedles by organic-solvent-free ice templating method. International journal of pharmaceutics. 2024-05-11. PMID:38734274. |
the poorly water-soluble asiatic acid was encapsulated in pmns in nanostructured lipid carriers, showing prominent hypertrophic scar healing trends. |
2024-05-11 |
2024-05-27 |
Not clear |
| Yize Li, Yujie Xiao, Yongfeng Han, Huayu Zhu, Juntao Han, Hongtao Wan. Blocking the MIR155HG/miR-155 axis reduces CTGF-induced inflammatory cytokine production and α-SMA expression via upregulating AZGP1 in hypertrophic scar fibroblasts. Cellular signalling. 2024-05-10. PMID:38729323. |
blocking the mir155hg/mir-155 axis reduces ctgf-induced inflammatory cytokine production and α-sma expression via upregulating azgp1 in hypertrophic scar fibroblasts. |
2024-05-10 |
2024-05-27 |
Not clear |
| Yize Li, Yujie Xiao, Yongfeng Han, Huayu Zhu, Juntao Han, Hongtao Wan. Blocking the MIR155HG/miR-155 axis reduces CTGF-induced inflammatory cytokine production and α-SMA expression via upregulating AZGP1 in hypertrophic scar fibroblasts. Cellular signalling. 2024-05-10. PMID:38729323. |
to investigate the mechanism of fibrosis, an in vitro model using ctgf-treated hypertrophic scar fibroblasts (hsfbs) was established and qrt-pcr, western blotting and elisa assays were performed to investigate the expression of interleukin (il)-1β, il-6, and mesenchymal markers α-smooth muscle actin (α-sma). |
2024-05-10 |
2024-05-27 |
Not clear |
| Hui Sun, Wei Shen, Yi Yao, Hui-Qiong Nie, Ying-Ming Ma, Hua-Jie Zhon. Deciphering long noncoding RNA dynamics in hypertrophic scar genesis post-severe burns. Burns : journal of the International Society for Burn Injuries. 2024-05-09. PMID:38724348. |
deciphering long noncoding rna dynamics in hypertrophic scar genesis post-severe burns. |
2024-05-09 |
2024-05-27 |
Not clear |
| Hua Guo, Qingmei Guo, Zhilin M. Kreotoxin A administration inhibits hyperproliferation and inflammation of human ear keloid tissue and keloid-derived fibroblasts by downregulating HIF-1α expression. Biochemical and biophysical research communications. vol 715. 2024-04-27. PMID:38676999. |
integrative microarray analysis revealed that hypoxia-inducible factor 1-alpha (hif-1α) expression was frequently upregulated in hypertrophic scar and keloid tissues, whereas it was downregulated in the kta-treated samples. |
2024-04-27 |
2024-04-30 |
human |
| Jianzhang Wang, Juan Du, Yuanyong Wang, Yajuan Song, Junzheng Wu, Tong Wang, Zhou Yu, Baoqiang Son. CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY. Biochimica et biophysica acta. Molecular basis of disease. 2024-04-26. PMID:38670440. |
hypertrophic scar (hs) is a skin fibroproliferative disorder occurring after burns, surgeries or traumatic injuries, and it has caused a tremendous economic and medical burden. |
2024-04-26 |
2024-04-29 |
Not clear |
| Jianzhang Wang, Juan Du, Yuanyong Wang, Yajuan Song, Junzheng Wu, Tong Wang, Zhou Yu, Baoqiang Son. CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY. Biochimica et biophysica acta. Molecular basis of disease. 2024-04-26. PMID:38670440. |
cilp2 promotes hypertrophic scar through snail acetylation by interaction with acly. |
2024-04-26 |
2024-04-29 |
Not clear |
| L X Zhang, D H H. [Research advances on the role of aerobic glycolysis in skin fibrosis diseases]. Zhonghua shao shang yu chuang mian xiu fu za zhi. vol 40. issue 4. 2024-04-25. PMID:38664034. |
skin fibrosis diseases mainly include hypertrophic scar, keloid, and systemic sclerosis, etc. |
2024-04-25 |
2024-04-28 |
Not clear |
| Jingjing Chen, Yan Mo, Yadan Chen, Zhouji Ma, Siyun Shen, Hong Sang, Qian Tan, Ran M. Application and effect of tension-reducing suture in surgical treatment of hypertrophic scar. BMC surgery. vol 24. issue 1. 2024-04-23. PMID:38654240. |
application and effect of tension-reducing suture in surgical treatment of hypertrophic scar. |
2024-04-23 |
2024-04-26 |
Not clear |
| Mike D Clague, Greg Goodman, Cindy Taing, Lauren Stuart, Margo Orsatti, John Holbrook, John Delaney, Bridgina Macka. Hyperdiluted Botulinum Toxin and Intense Pulsed Light Treatment: A Case Series to Illustrate a Novel Protocol for Hypertrophic Scar Reduction. Plastic and aesthetic nursing. vol 44. issue 2. 2024-04-19. PMID:38639968. |
hyperdiluted botulinum toxin and intense pulsed light treatment: a case series to illustrate a novel protocol for hypertrophic scar reduction. |
2024-04-19 |
2024-04-21 |
Not clear |
| b' Martin Knoz, Jakub Holoubek, B\\xc5\\x99etislav Lipov\\xc3\\xbd, Martin Faldyna, Radka Chaloupkov\\xc3\\xa1, Veronika Pavli\\xc5\\x88\\xc3\\xa1kov\\xc3\\xa1, Johana Muchov\\xc3\\xa1, Katar\\xc3\\xadna Kacvinsk\\xc3\\xa1, Jana Brtn\\xc3\\xadkov\\xc3\\xa1, Ji\\xc5\\x99\\xc3\\xad Jarkovsk\\xc3\\xbd, Lucy Vojtov\\xc3\\xa. Evaluation of viscoelastic parameters and photo-based assessment of newly developed dermal substitutes modified with thermostabilized fibroblast growth factor 2. Burns : journal of the International Society for Burn Injuries. 2024-04-19. PMID:38641499.' |
the application of dermal substitutes to the defect reduces the formation of hypertrophic scars and improves the scar quality. |
2024-04-19 |
2024-04-22 |
human |