| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Willem M van der Veer, Monica C T Bloemen, Magda M W Ulrich, Grietje Molema, Paul P van Zuijlen, Esther Middelkoop, Frank B Niesse. Potential cellular and molecular causes of hypertrophic scar formation. Burns : journal of the International Society for Burn Injuries. vol 35. issue 1. 2009-08-03. PMID:18952381. |
however, in some individuals, and particularly in burn victims, the wound healing processes may lead to a fibrotic hypertrophic scar, which is raised, red, inflexible and responsible for serious functional and cosmetic problems. |
2009-08-03 |
2023-08-12 |
Not clear |
| Willem M van der Veer, Monica C T Bloemen, Magda M W Ulrich, Grietje Molema, Paul P van Zuijlen, Esther Middelkoop, Frank B Niesse. Potential cellular and molecular causes of hypertrophic scar formation. Burns : journal of the International Society for Burn Injuries. vol 35. issue 1. 2009-08-03. PMID:18952381. |
it seems that a wide array of subsequent processes are involved in hypertrophic scar formation, like an affected haemostasis, exaggerated inflammation, prolonged reepithelialization, overabundant extracellular matrix production, augmented neovascularization, atypical extracellular matrix remodeling and reduced apoptosis. |
2009-08-03 |
2023-08-12 |
Not clear |
| Chuan Cao, Shirong Li, Xia Dai, Yanqing Chen, Zhi Feng, Yun Zhao, Jun W. Genistein inhibits proliferation and functions of hypertrophic scar fibroblasts. Burns : journal of the International Society for Burn Injuries. vol 35. issue 1. 2009-08-03. PMID:18976864. |
genistein inhibits proliferation and functions of hypertrophic scar fibroblasts. |
2009-08-03 |
2023-08-12 |
Not clear |
| Chuan Cao, Shirong Li, Xia Dai, Yanqing Chen, Zhi Feng, Yun Zhao, Jun W. Genistein inhibits proliferation and functions of hypertrophic scar fibroblasts. Burns : journal of the International Society for Burn Injuries. vol 35. issue 1. 2009-08-03. PMID:18976864. |
the purpose of this study was to investigate the effects of genistein on the proliferation and functions of hypertrophic scar fibroblasts (hsfbs) and the mechanism by which genistein inhibits tpk signal transduction. |
2009-08-03 |
2023-08-12 |
Not clear |
| Cesar Isaac, Mônica Beatriz Mathor, Giovani Bariani, André Oliveira Paggiaro, Marisa Roma Herson, Claudia Goldenstein-Schainberg, Solange Carrasco, Walcy Rosolia Teodoro, Natalino Hajime Yoshinari, Marcus Castro Ferreir. Pentoxifylline modifies three-dimensional collagen lattice model contraction and expression of collagen types I and III by human fibroblasts derived from post-burn hypertrophic scars and from normal skin. Burns : journal of the International Society for Burn Injuries. vol 35. issue 5. 2009-07-31. PMID:19303218. |
using a monolayer cell culture and fibroblast populated collagen lattice (fpcl) three-dimensional model we subjected hypertrophic scar and non-cicatricial fibroblasts to the antifibrogenic agent pentoxifylline (ptf - 1mg/ml) in order to reduce proliferation, collagen types i and iii synthesis and model contraction. |
2009-07-31 |
2023-08-12 |
human |
| Amin D Jaskille, Jeffrey W Shupp, James C Jeng, Marion H Jorda. Use of Integra in the treatment of third degree burns to the penile shaft: a case series with 6-month follow-up. Journal of burn care & research : official publication of the American Burn Association. vol 30. issue 3. 2009-07-31. PMID:19349885. |
third-degree burns to the penile shaft are serious injuries sometimes accompanied by poor healing, hypertrophic scar formation, painful erections, and dyspareunia. |
2009-07-31 |
2023-08-12 |
Not clear |
| Oliver Seifert, Ulrich Mrowiet. Keloid scarring: bench and bedside. Archives of dermatological research. vol 301. issue 4. 2009-07-09. PMID:19360429. |
the urgent need for better therapeutics is underlined by recent data substantiating an impaired quality of life in keloid and hypertrophic scar patients. |
2009-07-09 |
2023-08-12 |
Not clear |
| Xiao-bing F. [Strengthening the study of some key points in the management of local wounds after burns and trauma]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 23. issue 1. 2009-07-07. PMID:17605246. |
based on the advance in wound management in recent years, we emphasize the importance of paying much attention to study on mechanisms, prevention and treatment in local chronic wounds and hypertrophic scar. |
2009-07-07 |
2023-08-12 |
Not clear |
| Pei-Sheng Jin, Ying Cen, Xiao-Xue Liu, Jun-Jie Chen, Xue-Wen Xu, Yong Liu, Jing-Jing Li, Yaojun Wan. [Replication of pathological scar in nude mice]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 23. issue 2. 2009-07-07. PMID:17649888. |
to investigate the feasibility of reproduce hypertrophic scar and keloid in nude mice in the study of pathological scars. |
2009-07-07 |
2023-08-12 |
mouse |
| Heng Yao, Shi-Rong Li, Jian-Yi Liu, Zhe Li, Jun W. [Effects of Panax notoginseng on the transdifferentiation of fibroblasts in human hypertrophic scar in vitro]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 23. issue 3. 2009-07-07. PMID:18019057. |
[effects of panax notoginseng on the transdifferentiation of fibroblasts in human hypertrophic scar in vitro]. |
2009-07-07 |
2023-08-12 |
human |
| Heng Yao, Shi-Rong Li, Jian-Yi Liu, Zhe Li, Jun W. [Effects of Panax notoginseng on the transdifferentiation of fibroblasts in human hypertrophic scar in vitro]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 23. issue 3. 2009-07-07. PMID:18019057. |
to observe the effects of panax notoginseng on the transdifferentiation of the cultured human fibroblasts from hypertrophic scar in vitro, and explore its anti-fibrosis mechanism. |
2009-07-07 |
2023-08-12 |
human |
| Xi-Qiao Wang, Shu-Liang Lu, Zhi-Gang Mao, Ying-Kai Li. [Study on the biological function of vascular endothelial cells in the hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 23. issue 3. 2009-07-07. PMID:18019066. |
[study on the biological function of vascular endothelial cells in the hypertrophic scar]. |
2009-07-07 |
2023-08-12 |
Not clear |
| Xi-Qiao Wang, Shu-Liang Lu, Zhi-Gang Mao, Ying-Kai Li. [Study on the biological function of vascular endothelial cells in the hypertrophic scar]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 23. issue 3. 2009-07-07. PMID:18019066. |
to explore the biological function of vascular endothelial cells from hypertrophic scar, and to analyze the relationship between them. |
2009-07-07 |
2023-08-12 |
Not clear |
| Chuan Cao, Shi-Rong Li, Xia Dai, Yan-Qing Chen, Zhi Feng, Xia Qin, Yun Zhao, Jun W. [The effects of genistein on tyrosine protein kinase-mitogen activated protein kinase signal transduction pathway in hypertrophic scar fibroblasts]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 24. issue 2. 2009-07-07. PMID:18785412. |
[the effects of genistein on tyrosine protein kinase-mitogen activated protein kinase signal transduction pathway in hypertrophic scar fibroblasts]. |
2009-07-07 |
2023-08-12 |
Not clear |
| Chuan Cao, Shi-Rong Li, Xia Dai, Yan-Qing Chen, Zhi Feng, Xia Qin, Yun Zhao, Jun W. [The effects of genistein on tyrosine protein kinase-mitogen activated protein kinase signal transduction pathway in hypertrophic scar fibroblasts]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 24. issue 2. 2009-07-07. PMID:18785412. |
to investigate the inhibitory effects of genistein on tyrosine protein kinase (tpk)-mitogen activated protein kinase (mapk) signal transduction pathway in hypertrophic scar fibroblasts (hsfb), in order to explore the molecular mechanism of inhibition of scar hyperplasia by genistein. |
2009-07-07 |
2023-08-12 |
Not clear |
| Ping Yang, Ai-li Wang, De-wu Liu, Shun Xu, Yao-hui Gu, Jing Huang, Bo Chen, Qian-cheng Luo, Qing Jia, Zhi-hong W. [Effect of transfection of recombinant human endothelial nitric oxide synthase gene on hypertrophic scar fibroblasts in vitro]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 24. issue 4. 2009-07-07. PMID:19102984. |
[effect of transfection of recombinant human endothelial nitric oxide synthase gene on hypertrophic scar fibroblasts in vitro]. |
2009-07-07 |
2023-08-12 |
human |
| Ping Yang, Ai-li Wang, De-wu Liu, Shun Xu, Yao-hui Gu, Jing Huang, Bo Chen, Qian-cheng Luo, Qing Jia, Zhi-hong W. [Effect of transfection of recombinant human endothelial nitric oxide synthase gene on hypertrophic scar fibroblasts in vitro]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 24. issue 4. 2009-07-07. PMID:19102984. |
to investigate the feasibility of transfection of recombinant human endothelial nitric oxide synthase (enos) into human hypertrophic scar fibroblasts (hsfbs), and to observe no secretion and the synthesis of collagen i and iii. |
2009-07-07 |
2023-08-12 |
human |
| Mary H McGrath, David S Chan. Topical scar modification: hype or help? Aesthetic surgery journal. vol 25. issue 3. 2009-06-19. PMID:19338826. |
of the many topical scar modification treatments available, silicone gel sheeting is the only product shown to be effective for the treatment of hypertrophic scars. |
2009-06-19 |
2023-08-12 |
Not clear |
| Serge Mordo. [Thermal lasers and wound healing]. Revue medicale suisse. vol 5. issue 200. 2009-06-19. PMID:19438089. |
the wound healing is a complex biological process, which induces a dermal remodelling leading at minimum to a visible scar to an hypertrophic scar. |
2009-06-19 |
2023-08-12 |
Not clear |
| Berish Strauch, Diana Linetskaya, Thomas Baum, David Greenspu. Brachioplasty and axillary restoration. Aesthetic surgery journal. vol 24. issue 5. 2009-06-18. PMID:19336200. |
the sinusoidal-shaped scar helps to avoid problems such as linear scar contracture, wound tension, and widened or hypertrophic scars. |
2009-06-18 |
2023-08-12 |
Not clear |