| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhigang Xu, Chuantao Cheng, Yangang Zhang, Danyang Yang, Wenwen Jing, Xin Liu, Xiaoli L. Lipopolysaccharide induces skin scarring through the TLR4/Myd88 inflammatory signaling pathway in dermal fibroblasts. Burns : journal of the International Society for Burn Injuries. 2023-10-11. PMID:37821278. |
in this study, hypertrophic scar derived fibroblasts (hsfs) and paired normal skin derived fibroblasts (nsfs) were used to evaluate the effects of lipopolysaccharide (lps) on inflammation-induced skin scarring and explore the inflammation-mediated mechanism of activity of lps on dermal fibroblasts. |
2023-10-11 |
2023-10-15 |
mouse |
| Chang Liu, Hailong Zhang, Xiaoqian Cui, Shanshan Wang, Quanyu Zho. The effects of Shikonin on the hypertrophic scar of rabbit ears via the TLR4/NF-κB signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 9. 2023-10-09. PMID:37807317. |
the effects of shikonin on the hypertrophic scar of rabbit ears via the tlr4/nf-κb signaling pathway. |
2023-10-09 |
2023-10-15 |
rat |
| Chang Liu, Hailong Zhang, Xiaoqian Cui, Shanshan Wang, Quanyu Zho. The effects of Shikonin on the hypertrophic scar of rabbit ears via the TLR4/NF-κB signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 9. 2023-10-09. PMID:37807317. |
as a result, we created the newland white rabbit ear hs model, administered shikonin to it, and then assessed scar hypertrophy using he and vg staining. |
2023-10-09 |
2023-10-15 |
rat |
| Shyla Kajal Bharadia, Lindsay Burnett, Vincent Gabrie. Hypertrophic Scar. Physical medicine and rehabilitation clinics of North America. vol 34. issue 4. 2023-10-08. PMID:37806697. |
hypertrophic scar. |
2023-10-08 |
2023-10-15 |
Not clear |
| Shyla Kajal Bharadia, Lindsay Burnett, Vincent Gabrie. Hypertrophic Scar. Physical medicine and rehabilitation clinics of North America. vol 34. issue 4. 2023-10-08. PMID:37806697. |
this article aims to synthesize knowledge on the clinical and molecular development, evolution, management, and measurement of hypertrophic burn scar for both patient and clinician knowledge. |
2023-10-08 |
2023-10-15 |
Not clear |
| Barclay T Stewart, Clifford C Sheckter, Kiran K Nakarm. Holistic Approach to Burn Reconstruction and Scar Rehabilitation. Physical medicine and rehabilitation clinics of North America. vol 34. issue 4. 2023-10-08. PMID:37806704. |
many people with burn injuries, regardless of injury size, develop hypertrophic scar, contracture, unstable scar, heterotopic ossification, and disability resulting from these sequelae. |
2023-10-08 |
2023-10-15 |
Not clear |
| Kevin G Burt, Dan C Viola, Lauren E Lisiewski, Joseph M Lombardi, Louis F Amorosa, Nadeen O Chahin. An in vivo model of ligamentum flavum hypertrophy from early-stage inflammation to fibrosis. JOR spine. vol 6. issue 3. 2023-10-02. PMID:37780823. |
clinical hypertrophic lf is characterized by a loss of elastic fibers and increase in collagen fibers, resulting in fibrotic thickening and scar formation. |
2023-10-02 |
2023-10-07 |
rat |
| Yixiu Zhong, Youfan Zhang, Aijiao Yu, Zhiwen Zhang, Zhenjun Deng, Kaifen Xiong, Qi Wang, Jianglin Zhan. Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms. Frontiers in physiology. vol 14. 2023-10-02. PMID:37781228. |
therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms. |
2023-10-02 |
2023-10-07 |
Not clear |
| Yixiu Zhong, Youfan Zhang, Aijiao Yu, Zhiwen Zhang, Zhenjun Deng, Kaifen Xiong, Qi Wang, Jianglin Zhan. Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms. Frontiers in physiology. vol 14. 2023-10-02. PMID:37781228. |
previous studies suggested that mesenchymal stem cell (msc)-derived exosomes could either suppress or support keloid and hypertrophic scar progression. |
2023-10-02 |
2023-10-07 |
Not clear |
| Yixiu Zhong, Youfan Zhang, Aijiao Yu, Zhiwen Zhang, Zhenjun Deng, Kaifen Xiong, Qi Wang, Jianglin Zhan. Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms. Frontiers in physiology. vol 14. 2023-10-02. PMID:37781228. |
although previous research has identified the potential value of msc-exosomes in keloid and hypertrophic scar, a comprehensive analysis of different sources of msc-exosome in keloid and hypertrophic scar is still lacking. |
2023-10-02 |
2023-10-07 |
Not clear |
| Yixiu Zhong, Youfan Zhang, Aijiao Yu, Zhiwen Zhang, Zhenjun Deng, Kaifen Xiong, Qi Wang, Jianglin Zhan. Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms. Frontiers in physiology. vol 14. 2023-10-02. PMID:37781228. |
this review mainly discusses different insights regarding the roles of msc-exosomes in keloid and hypertrophic scar treatment and summarizes possible underlying mechanisms. |
2023-10-02 |
2023-10-07 |
Not clear |
| Bonnie C Carney, Taryn E Travis, John W Keyloun, Lauren T Moffatt, Laura S Johnson, Melissa M McLawhorn, Jeffrey W Shup. Rete ridges are decreased in dyschromic burn hypertrophic scar: A histological study. Burns : journal of the International Society for Burn Injuries. 2023-09-30. PMID:37777456. |
rete ridges are decreased in dyschromic burn hypertrophic scar: a histological study. |
2023-09-30 |
2023-10-07 |
human |
| Bonnie C Carney, Taryn E Travis, John W Keyloun, Lauren T Moffatt, Laura S Johnson, Melissa M McLawhorn, Jeffrey W Shup. Rete ridges are decreased in dyschromic burn hypertrophic scar: A histological study. Burns : journal of the International Society for Burn Injuries. 2023-09-30. PMID:37777456. |
dyschromic hypertrophic scar (hts) is a common sequelae of burn injury, however, its mechanism has not been elucidated. |
2023-09-30 |
2023-10-07 |
human |
| Bonnie C Carney, Taryn E Travis, John W Keyloun, Lauren T Moffatt, Laura S Johnson, Melissa M McLawhorn, Jeffrey W Shup. Rete ridges are decreased in dyschromic burn hypertrophic scar: A histological study. Burns : journal of the International Society for Burn Injuries. 2023-09-30. PMID:37777456. |
subjects with dyschromic burn hypertrophic scar were prospectively enrolled (n = 44). |
2023-09-30 |
2023-10-07 |
human |
| Bonnie C Carney, Taryn E Travis, John W Keyloun, Lauren T Moffatt, Laura S Johnson, Melissa M McLawhorn, Jeffrey W Shup. Rete ridges are decreased in dyschromic burn hypertrophic scar: A histological study. Burns : journal of the International Society for Burn Injuries. 2023-09-30. PMID:37777456. |
though, contrary to our hypothesis, no direct link between the extent of dyschromia and rete ridge quantity was observed, the differences in normal skin and hypertrophic scar may lead to further understanding of dyschromic scars. |
2023-09-30 |
2023-10-07 |
human |
| Yunxian Dong, Xiaoling Cao, Jinsheng Huang, Zhicheng Hu, Chufen Chen, Miao Chen, Qian Long, Zhongye Xu, Dongming Lv, Yanchao Rong, Shengkang Luo, Haibin Wang, Wuguo Deng, Bing Tan. Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling. Biochimica et biophysica acta. Molecular basis of disease. 2023-09-22. PMID:37739092. |
melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the mt2 receptor-inhibited pi3k/akt /mtor signaling. |
2023-09-22 |
2023-10-07 |
human |
| Yunxian Dong, Xiaoling Cao, Jinsheng Huang, Zhicheng Hu, Chufen Chen, Miao Chen, Qian Long, Zhongye Xu, Dongming Lv, Yanchao Rong, Shengkang Luo, Haibin Wang, Wuguo Deng, Bing Tan. Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling. Biochimica et biophysica acta. Molecular basis of disease. 2023-09-22. PMID:37739092. |
hypertrophic scar (hs) is a fibrotic skin condition and characterized by abnormal proliferation of myofibroblasts and accumulation of extracellular matrix. |
2023-09-22 |
2023-10-07 |
human |
| Sheng Meng, Qian Wei, Shengqiu Chen, Xi Liu, Shengnan Cui, Qilin Huang, Ziqiang Chu, Kui Ma, Wenhua Zhang, Wenzhi Hu, Shiyi Li, Zihao Wang, Lige Tian, Zhiliang Zhao, Haihong Li, Xiaobing Fu, Cuiping Zhan. MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment. Small (Weinheim an der Bergstrasse, Germany). 2023-09-19. PMID:37724002. |
mir-141-3p-functionalized exosomes loaded in dissolvable microneedle arrays for hypertrophic scar treatment. |
2023-09-19 |
2023-10-07 |
Not clear |
| Sheng Meng, Qian Wei, Shengqiu Chen, Xi Liu, Shengnan Cui, Qilin Huang, Ziqiang Chu, Kui Ma, Wenhua Zhang, Wenzhi Hu, Shiyi Li, Zihao Wang, Lige Tian, Zhiliang Zhao, Haihong Li, Xiaobing Fu, Cuiping Zhan. MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment. Small (Weinheim an der Bergstrasse, Germany). 2023-09-19. PMID:37724002. |
hypertrophic scar (hs) is a common fibroproliferative disease caused by abnormal wound healing after deep skin injury. |
2023-09-19 |
2023-10-07 |
Not clear |
| Sheng Meng, Qian Wei, Shengqiu Chen, Xi Liu, Shengnan Cui, Qilin Huang, Ziqiang Chu, Kui Ma, Wenhua Zhang, Wenzhi Hu, Shiyi Li, Zihao Wang, Lige Tian, Zhiliang Zhao, Haihong Li, Xiaobing Fu, Cuiping Zhan. MiR-141-3p-Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment. Small (Weinheim an der Bergstrasse, Germany). 2023-09-19. PMID:37724002. |
in this study, a mirna, mir-141-3p, which is downregulated in skin scar tissues and in hypertrophic scar fibroblasts (hsfs), is identified. |
2023-09-19 |
2023-10-07 |
Not clear |