| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael V Sofroniew, Harry V Vinter. Astrocytes: biology and pathology. Acta neuropathologica. vol 119. issue 1. 2010-03-15. PMID:20012068. |
these changes range from reversible alterations in gene expression and cell hypertrophy with preservation of cellular domains and tissue structure, to long-lasting scar formation with rearrangement of tissue structure. |
2010-03-15 |
2023-08-12 |
mouse |
| Michael T Longake. Regenerative medicine: a surgeon's perspective. Journal of pediatric surgery. vol 45. issue 1. 2010-03-12. PMID:20105574. |
and "why do we always heal with either a 'normal amount of scarring' or, approximately 15% of the time, with a pathologic amount of scarring (hypertrophic scar or keloid)?" |
2010-03-12 |
2023-08-12 |
Not clear |
| Florian Lang, Agnes Görlac. Heterocyclic indazole derivatives as SGK1 inhibitors, WO2008138448. Expert opinion on therapeutic patents. vol 20. issue 1. 2010-03-09. PMID:20021289. |
heterocyclic indazole derivatives are claimed in patent wo2008138448 as inhibitors of the serum- and glucocorticoid-inducible-kinase 1 (sgk1) and drugs for the pharmacological treatment of sgk1-related diseases, such as diabetes, obesity, metabolic syndrome, systemic and pulmonary hypertension, cardiac fibrosis, hypertrophy and insufficiency, arteriosclerosis, glomerulosclerosis, nephrosclerosis, nephritis, nephropathy, deranged electrolyte excretion, fibrosing and inflammatory disease (e.g., liver cirrhosis, lung fibrosis, rheumatism, arthrosis, crohn s disease, chronic bronchitis, radiation fibrosis, sclerodermia, cystic fibrosis, scar formation and alzheimer' disease), tumor growth, peptic ulcers and some disorders hitherto not conclusively shown to involve sgk1. |
2010-03-09 |
2023-08-12 |
Not clear |
| Vibhu Sahni, Abhishek Mukhopadhyay, Vicki Tysseling, Amy Hebert, Derin Birch, Tammy L Mcguire, Samuel I Stupp, John A Kessle. BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 5. 2010-03-05. PMID:20130193. |
astrogliosis following spinal cord injury (sci) involves an early hypertrophic response that is beneficial and a subsequent formation of a dense scar. |
2010-03-05 |
2023-08-12 |
mouse |
| J F Sobanko, T S Alste. Laser treatment for scars and wounds. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. vol 144. issue 5. 2010-03-01. PMID:19834436. |
consequently, this may manifest in various maladies such as ulceration if re-epithelialization fails to occur or a hypertrophic scar or keloid if the wound healing process becomes too exuberant. |
2010-03-01 |
2023-08-12 |
Not clear |
| Jaspal Ricky Singh, Uzoma Nwosu, Kenneth A Ego. Long-term functional outcome and donor-site morbidity associated with autogenous iliac crest bone grafts utilizing a modified anterior approach. Bulletin of the NYU hospital for joint diseases. vol 67. issue 4. 2010-03-01. PMID:20001937. |
other minor complications included hypertrophic scar formation (7%) and hematoma/seroma (3%). |
2010-03-01 |
2023-08-12 |
Not clear |
| Alexandre Capon, Gwen Iarmarcovai, Serge Mordo. Laser-assisted skin healing (LASH) in hypertrophic scar revision. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. vol 11. issue 4. 2010-02-22. PMID:19951192. |
laser-assisted skin healing (lash) in hypertrophic scar revision. |
2010-02-22 |
2023-08-12 |
Not clear |
| Alexandre Capon, Gwen Iarmarcovai, Serge Mordo. Laser-assisted skin healing (LASH) in hypertrophic scar revision. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. vol 11. issue 4. 2010-02-22. PMID:19951192. |
a 47-year-old woman (skin type ii), who developed systematically hypertrophic scars after surgery, was enrolled for a hypertrophic scar revision. |
2010-02-22 |
2023-08-12 |
Not clear |
| Alexandre Capon, Gwen Iarmarcovai, Serge Mordo. Laser-assisted skin healing (LASH) in hypertrophic scar revision. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. vol 11. issue 4. 2010-02-22. PMID:19951192. |
no recurrence of hypertrophic scarring was noticed 6 months after scar revision. |
2010-02-22 |
2023-08-12 |
Not clear |
| Alexandre Capon, Gwen Iarmarcovai, Serge Mordo. Laser-assisted skin healing (LASH) in hypertrophic scar revision. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. vol 11. issue 4. 2010-02-22. PMID:19951192. |
this study reports, for the first time, the possibility of improving the appearance of hypertrophic scarring in scar revision by altering through thermal stress the wound-healing process. |
2010-02-22 |
2023-08-12 |
Not clear |
| Zhi-dong Cao, Chong-rong Shi, Chong-ben Huang, Bang-chun Li, Jing-yue Gou, Yuan-lu Liu, Kui Zhan. [The effects of tetrandrine on activity of collagenase derived from human hypertrophic scar]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 22. issue 6. 2010-02-16. PMID:17286006. |
[the effects of tetrandrine on activity of collagenase derived from human hypertrophic scar]. |
2010-02-16 |
2023-08-12 |
human |
| Zhi-dong Cao, Chong-rong Shi, Chong-ben Huang, Bang-chun Li, Jing-yue Gou, Yuan-lu Liu, Kui Zhan. [The effects of tetrandrine on activity of collagenase derived from human hypertrophic scar]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 22. issue 6. 2010-02-16. PMID:17286006. |
to observe the effect of tetrandrine on activity of collagenase derived from human hypertrophic scar for the sake of clarifying the mechanism as tetrandrine acting on scar. |
2010-02-16 |
2023-08-12 |
human |
| Xi-Qiao Wang, Ying-Kai Liu, Chun Qing, Shu-Liang L. A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids. Annals of plastic surgery. vol 63. issue 6. 2010-02-05. PMID:19887927. |
the current accepted treatment for hypertrophic scar and keloid are combination therapy and the early treatment which could achieve better efficacy and less adverse effect. |
2010-02-05 |
2023-08-12 |
Not clear |
| Guang-Qing Wang, Zhao-Fan Xi. Transplantation of epidermis of scar tissue on acellular dermal matrix. Burns : journal of the International Society for Burn Injuries. vol 35. issue 3. 2010-02-02. PMID:18951705. |
this study enrolled 22 participants with hypertrophic scarring after burn who received treatment with co-transplantation of acellular dermal matrix and epidermis of either normal skin or scar tissue. |
2010-02-02 |
2023-08-12 |
human |
| Guang-Qing Wang, Zhao-Fan Xi. Transplantation of epidermis of scar tissue on acellular dermal matrix. Burns : journal of the International Society for Burn Injuries. vol 35. issue 3. 2010-02-02. PMID:18951705. |
however, if co-transplanted on acellular dermal matrix, this effectively inhibited scar formation and pruritus, providing an alternative method to treat hypertrophic scarring. |
2010-02-02 |
2023-08-12 |
human |
| Amín D Jaskille, Jeffrey W Shupp, Marion H Jordan, James C Jen. Critical review of burn depth assessment techniques: Part I. Historical review. Journal of burn care & research : official publication of the American Burn Association. vol 30. issue 6. 2010-01-26. PMID:19898102. |
a false-positive assessment and the patient faces needless surgery, a false-negative one and the patient faces increased length of stay, risks contracture, and hypertrophic scar formation. |
2010-01-26 |
2023-08-12 |
Not clear |
| Ling Qin, Lin Wang, Margaret Wan-nar Wong, Chunyi Wen, Gang Wang, Ge Zhang, Kai-ming Chan, Wing-hoi Cheung, Kwok-sui Leun. Osteogenesis induced by extracorporeal shockwave in treatment of delayed osteotendinous junction healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 28. issue 1. 2010-01-20. PMID:19603517. |
scar tissue formed at the otj healing interface of the dh group, whereas esw triggered high expression of vegf in hypertrophic chondrocytes at week 8 and regeneration of the fibrocartilage zone at week 12 postoperatively. |
2010-01-20 |
2023-08-12 |
Not clear |
| Alwin Scharstuhl, Henricus A M Mutsaers, Sebastiaan W C Pennings, Frans G M Russel, Frank A D T G Wagene. Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis. PloS one. vol 4. issue 8. 2010-01-19. PMID:19693275. |
we previously identified curcumin as a potent inducer of fibroblast apoptosis, which could be used to treat hypertrophic scar formation. |
2010-01-19 |
2023-08-12 |
Not clear |
| Chun-mei Wang, Hyakusoku Hiko, Nando Nakazaw. [Investigation of p53 polymorphism for genetic predisposition of keloid and hypertrophic scar]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 21. issue 1. 2010-01-07. PMID:15844595. |
[investigation of p53 polymorphism for genetic predisposition of keloid and hypertrophic scar]. |
2010-01-07 |
2023-08-12 |
Not clear |
| Chun-mei Wang, Hyakusoku Hiko, Nando Nakazaw. [Investigation of p53 polymorphism for genetic predisposition of keloid and hypertrophic scar]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 21. issue 1. 2010-01-07. PMID:15844595. |
to investigate the codon-72 polymorphism of the tumor suppressor gene p53, codon-72 encodes arginine (arg) or proline (pro) for a genetic predisposition,to keloid or hypertrophic scar. |
2010-01-07 |
2023-08-12 |
Not clear |