| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhibo Xiao, Miaobo Zhang, Ying Liu, Lihong Re. Botulinum toxin type a inhibits connective tissue growth factor expression in fibroblasts derived from hypertrophic scar. Aesthetic plastic surgery. vol 35. issue 5. 2012-02-10. PMID:21455826. |
the effects of btxa on ctgf in hypertrophic scar still are unknown. |
2012-02-10 |
2023-08-12 |
Not clear |
| Zhibo Xiao, Miaobo Zhang, Ying Liu, Lihong Re. Botulinum toxin type a inhibits connective tissue growth factor expression in fibroblasts derived from hypertrophic scar. Aesthetic plastic surgery. vol 35. issue 5. 2012-02-10. PMID:21455826. |
this study aimed to explore the effect of btxa on ctgf in fibroblasts derived from hypertrophic scar and to elucidate its actual mechanism further. |
2012-02-10 |
2023-08-12 |
Not clear |
| Ji-Sup Yun, Young-Jun Choi, Won-Serk Kim, Ga-Young Le. Prevention of thyroidectomy scars in Asian adults using a 532-nm potassium titanyl phosphate laser. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. vol 37. issue 12. 2012-02-07. PMID:21883646. |
prediction of whether postoperative wound healing will result in a hypertrophic scar or keloid is difficult. |
2012-02-07 |
2023-08-12 |
Not clear |
| Rei Ogawa, Satoshi Akaishi, Chenyu Huang, Teruyuki Dohi, Masayo Aoki, Yasutaka Omori, Sachiko Koike, Kyoko Kobe, Masataka Akimoto, Hiko Hyakusok. Clinical applications of basic research that shows reducing skin tension could prevent and treat abnormal scarring: the importance of fascial/subcutaneous tensile reduction sutures and flap surgery for keloid and hypertrophic scar reconstruction. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. vol 78. issue 2. 2012-02-03. PMID:21551963. |
clinical applications of basic research that shows reducing skin tension could prevent and treat abnormal scarring: the importance of fascial/subcutaneous tensile reduction sutures and flap surgery for keloid and hypertrophic scar reconstruction. |
2012-02-03 |
2023-08-12 |
Not clear |
| Shengxian Jia, Yanan Zhao, Thomas A Musto. The effects of topically applied silicone gel and its silver derivative on the prevention of hypertrophic scarring in two rabbit ear-scarring models. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 64. issue 12. 2012-01-19. PMID:21665562. |
both the 7 mm and new 10 mm scar models were used to study the effectiveness of silicone gel and silicone gel silver respectively on hypertrophy and the inhibition of scar formation. |
2012-01-19 |
2023-08-12 |
rabbit |
| Shengxian Jia, Yanan Zhao, Thomas A Musto. The effects of topically applied silicone gel and its silver derivative on the prevention of hypertrophic scarring in two rabbit ear-scarring models. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 64. issue 12. 2012-01-19. PMID:21665562. |
the new 10 mm scar model resulted in more hypertrophic scarring than the typical, 7 mm wound scar model (p=0.0001). |
2012-01-19 |
2023-08-12 |
rabbit |
| Shengxian Jia, Yanan Zhao, Thomas A Musto. The effects of topically applied silicone gel and its silver derivative on the prevention of hypertrophic scarring in two rabbit ear-scarring models. Journal of plastic, reconstructive & aesthetic surgery : JPRAS. vol 64. issue 12. 2012-01-19. PMID:21665562. |
in conclusion, silicone gel and its silver derivative are effective in preventing hypertrophic scarring and scar models that leave the perichondrium intact causes scars with more hypertrophy. |
2012-01-19 |
2023-08-12 |
rabbit |
| Vasudev B Pai, Ian Cumming. Are there any good treatments for keloid scarring after sternotomy? Interactive cardiovascular and thoracic surgery. vol 13. issue 4. 2012-01-12. PMID:21737540. |
the question addressed was: in patients with hypertrophic and keloid scarring of the sternotomy wound, is surgical excision with or without adjuvant treatment of any benefit in reducing the size of the scar? |
2012-01-12 |
2023-08-12 |
Not clear |
| Vincent Sarrazy, Fabrice Billet, Ludovic Micallef, Bernard Coulomb, Alexis Desmoulièr. Mechanisms of pathological scarring: role of myofibroblasts and current developments. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 19 Suppl 1. 2012-01-12. PMID:21793960. |
embryonic skin wounds are repaired without scarring or fibrosis, whereas skin wound repair in adults always leads to scar formation, which may have functional or esthetic consequences, as in the case of hypertrophic scars, for example. |
2012-01-12 |
2023-08-12 |
Not clear |
| Rei Ogaw. Mechanobiology of scarring. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 19 Suppl 1. 2012-01-12. PMID:21793962. |
the mechanophysiological conditions of injured skin greatly influence the degree of scar formation, scar contracture, and abnormal scar progression/generation (e.g., keloids and hypertrophic scars). |
2012-01-12 |
2023-08-12 |
Not clear |
| Luc Téot, Sami Otman, Chloé Trial, Antonio Brancat. The use of noncellularized artificial dermis in the prevention of scar contracture and hypertrophy. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 19 Suppl 1. 2012-01-12. PMID:21793966. |
the use of noncellularized artificial dermis in the prevention of scar contracture and hypertrophy. |
2012-01-12 |
2023-08-12 |
Not clear |
| Xue-Qing Wang, Olena Kravchuk, Clay Winterford, Roy M Kimbl. The correlation of in vivo burn scar contraction with the level of α-smooth muscle actin expression. Burns : journal of the International Society for Burn Injuries. vol 37. issue 8. 2012-01-05. PMID:21855218. |
to our knowledge, this is the first study to provide in vivo evidence of the association of α-sma expression with scar contraction, scar thickness, re-epithelialisation time and the depth of burn in a large animal burn model with scars similar to human hypertrophic scar. |
2012-01-05 |
2023-08-12 |
human |
| Sergio Monteiro Lima, Luciana Asprino, Roger Willian Fernandes Moreira, Márcio de Morae. Surgical complications of mandibular condylar fractures. The Journal of craniofacial surgery. vol 22. issue 4. 2011-12-29. PMID:21778851. |
there were no cases of hypertrophic scar, frey syndrome, or salivary fistula. |
2011-12-29 |
2023-08-12 |
Not clear |
| Mathew Varkey, Jie Ding, Edward E Tredge. Differential collagen-glycosaminoglycan matrix remodeling by superficial and deep dermal fibroblasts: potential therapeutic targets for hypertrophic scar. Biomaterials. vol 32. issue 30. 2011-12-12. PMID:21802722. |
differential collagen-glycosaminoglycan matrix remodeling by superficial and deep dermal fibroblasts: potential therapeutic targets for hypertrophic scar. |
2011-12-12 |
2023-08-12 |
Not clear |
| Yan Wo, Zhen Zhang, Yixin Zhang, Danru Wang, Zheming Pu, Weijie Su, Yunliang Qian, Yunwu Li, Daxiang Cu. Preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar. Journal of nanoscience and nanotechnology. vol 11. issue 9. 2011-12-06. PMID:22097495. |
preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar. |
2011-12-06 |
2023-08-12 |
Not clear |
| Yan Wo, Zhen Zhang, Yixin Zhang, Danru Wang, Zheming Pu, Weijie Su, Yunliang Qian, Yunwu Li, Daxiang Cu. Preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar. Journal of nanoscience and nanotechnology. vol 11. issue 9. 2011-12-06. PMID:22097495. |
within 24 hours, in the group of 5-fu es, the penetration amount of 5-fu in scar was 14.12 +/- 0.1 microg/ml/cm2, the retention contents of 5-fu was 10.74 +/- 1.17 microg/cm2, and the fluorescence intensity of rho in hypertrophic scar tissues were 182 +/- 18.3; in the group of 5-fu ds: the penetration amount of 5-fu was 12.35 +/- 1.21 microg/mlcm2; the retention contents of 5-fu was 17.48 +/- 0.82 microg/cm2, and the fluorescence intensity of rho was 241.45 +/- 7.63; there existed statistical difference between penetration amount in the group of 5-fu es and that in the group of 5-fu ds as well as control groups (p < 0.05, p < 0.01), the penetration amount in the group of es is markedly higher than ds group or control groups. |
2011-12-06 |
2023-08-12 |
Not clear |
| Yan Wo, Zhen Zhang, Yixin Zhang, Danru Wang, Zheming Pu, Weijie Su, Yunliang Qian, Yunwu Li, Daxiang Cu. Preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar. Journal of nanoscience and nanotechnology. vol 11. issue 9. 2011-12-06. PMID:22097495. |
es has better permeability of 5-fu than ds, ds has higher entrapment efficiency of 5-fu, and more 5-fu deposition in hypertrophic scar than es. |
2011-12-06 |
2023-08-12 |
Not clear |
| Yan Wo, Zhen Zhang, Yixin Zhang, Danru Wang, Zheming Pu, Weijie Su, Yunliang Qian, Yunwu Li, Daxiang Cu. Preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar. Journal of nanoscience and nanotechnology. vol 11. issue 9. 2011-12-06. PMID:22097495. |
we should select es or ds encapsulated with 5-fu according to clinical demand for hypertrophic scar therapy. |
2011-12-06 |
2023-08-12 |
Not clear |
| Kevin L McFarland, Kathryn Glaser, Jennifer M Hahn, Steven T Boyce, Dorothy M Sup. Culture medium and cell density impact gene expression in normal skin and abnormal scar-derived fibroblasts. Journal of burn care & research : official publication of the American Burn Association. vol 32. issue 4. 2011-11-23. PMID:21747336. |
disruption of either production or degradation of extracellular matrix can lead to abnormal scarring, resulting in hypertrophic scar or keloid scar. |
2011-11-23 |
2023-08-12 |
human |
| Vincent Gabrie. Hypertrophic scar. Physical medicine and rehabilitation clinics of North America. vol 22. issue 2. 2011-11-22. PMID:21624722. |
hypertrophic scar. |
2011-11-22 |
2023-08-12 |
Not clear |