Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
N Kokkorakis, K Douka, A Nalmpanti, P K Politis, L Zagoraiou, R Matsas, M Gaitano. Mirk/Dyrk1B controls ventral spinal cord development via Shh pathway. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-01-31. PMID:38294527. |
here, we reveal a novel role for dyrk1b in regulating ventral progenitor and neuron subtypes in the embryonic chick spinal cord (sc) via the shh pathway. |
2024-01-31 |
2024-02-02 |
chicken |
Vincent Auffret, Aude Castel, Tristan Juette, Cyrielle Finc. Residual volume of extruded disc material and residual spinal cord compression measured on postoperative MRI do not predict neurological outcomes in dogs following decompressive surgery for thoracolumbar intervertebral disc extrusion. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 2024-01-06. PMID:38183621. |
published studies on the validity of using quantitative mri measures of pre- and postoperative spinal cord (sc) compression as prognostic indicators for dogs undergoing surgery for intervertebral disc extrusion (ivde) are currently limited. |
2024-01-06 |
2024-01-09 |
Not clear |
Ayikoe-Guy Mensah-Nyagan, Laurence Meyer, Christine Patte-Mensa. Modulatory role of neurosteroidogenesis in the spinal cord during peripheral nerve injury-induced chronic pain. Frontiers in neuroendocrinology. 2024-01-05. PMID:38182090. |
the brain and spinal cord (sc) are both targeted by various hormones, including steroid hormones. |
2024-01-05 |
2024-01-08 |
Not clear |
Alice Bruel, Ignacio Abadía, Thibault Collin, Icare Sakr, Henri Lorach, Niceto R Luque, Eduardo Ros, Auke Ijspeer. The spinal cord facilitates cerebellar upper limb motor learning and control; inputs from neuromusculoskeletal simulation. PLoS computational biology. vol 20. issue 1. 2024-01-02. PMID:38166093. |
complex interactions between brain regions and the spinal cord (sc) govern body motion, which is ultimately driven by muscle activation. |
2024-01-02 |
2024-01-10 |
human |
Mousumi Ghosh, Damien D Pears. Schwann Cell-Derived Exosomal Vesicles: A Promising Therapy for the Injured Spinal Cord. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139147. |
considering the therapeutic potential of exosomes, the current review seeks to specifically examine an area of investigation that encompasses the development of schwann cell (sc)-derived exosomal vesicles (scevs) as an approach to spinal cord injury (sci) protection and repair. |
2023-12-23 |
2023-12-25 |
human |
Mousumi Ghosh, Damien D Pears. Schwann Cell-Derived Exosomal Vesicles: A Promising Therapy for the Injured Spinal Cord. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139147. |
this review delves into the potential of utilizing scevs as a therapy for sci, explores promising engineering strategies to customize scevs for specific actions, and examines how scevs may offer unique clinical advantages over sc transplantation for repair of the injured spinal cord. |
2023-12-23 |
2023-12-25 |
human |
Kai Sun, Hao Zhang, Ting Zhang, Nan Sun, Jingru Hao, Zhiping Wang, Can Ga. Spinal HDAC6 mediates nociceptive behaviors induced by CCI via neuronal activation and neuroinflammation. Molecular pain. 2023-11-20. PMID:37982151. |
our findings indicate that hdac6 expression in the spinal cord (sc) is upregulated in a time-dependent manner following chronic constriction injury (cci). |
2023-11-20 |
2023-11-29 |
Not clear |
Paolo Tollis, Erika Vitiello, Francesco Migliaccio, Eleonora D'Ambra, Anna Rocchegiani, Maria Giovanna Garone, Irene Bozzoni, Alessandro Rosa, Annamaria Carissimo, Pietro Laneve, Elisa Caffarell. The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons. Cell death & disease. vol 14. issue 11. 2023-11-14. PMID:37963881. |
in the central nervous system (cns), motor neurons (mns) are responsible for controlling essential functions such as movement, breathing, and swallowing by integrating signal transmission from the cortex, brainstem, and spinal cord (sc) towards peripheral muscles. |
2023-11-14 |
2023-11-20 |
human |
Sonsoles Barriola, Lina María Delgado-García, Paz Cartas-Cejudo, Ignacio Iñigo-Marco, Joaquín Fernández-Irigoyen, Enrique Santamaría, Laura López-Mascaraqu. Orm1 arises as a shared altered protein in two models of Multiple Sclerosis. Neuroscience. 2023-11-10. PMID:37949310. |
specifically, we focused on two different regions of the cns: the dorsal cortex (cx) and the entire spinal cord (sc). |
2023-11-10 |
2023-11-20 |
mouse |
Jie Fan, Xiaocheng Li, Peiyu Wang, Fan Yang, Bingzhen Zhao, Jianing Yang, Zhengtuo Zhao, Xue L. A Hyperflexible Electrode Array for Long-Term Recording and Decoding of Intraspinal Neuronal Activity. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023-10-23. PMID:37870208. |
neural interfaces for stable access to the spinal cord (sc) electrical activity can benefit patients with motor dysfunctions. |
2023-10-23 |
2023-11-08 |
mouse |
Deniz Pehlivan, Ali Yucel Kara, Ahmet Koyu, Fatma Simse. Enhancing Fentanyl Antinociception and Preventing Tolerance with α-2 Adrenoceptor Agonists in Rats. Behavioural brain research. 2023-10-21. PMID:37865211. |
this study examined the effects of α-2 adrenoceptor (ar) agonists, dexmedetomidine (dex), and xylazine (xyl) on fen tolerance and antinociception, and their impact on μ-opioid receptor (mor) expression in the posterior horn of the spinal cord (sc). |
2023-10-21 |
2023-11-08 |
rat |
Ricardo S Harripaul, Elisabetta S Morini, Monica Salani, Emily Logan, Emily Grace Kirchner, Jessica Bolduc, Anil Chekuri, Benjamin Currall, Rachita Yadav, Serkan Erdin, Michael E Talkowski, Dadi Gao, Susan Slaugenhaup. Transcriptome analysis in a humanized mouse model of familial dysautonomia reveals tissue-specific gene expression disruption in the peripheral nervous system. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808686. |
comparison of fd and control transcriptomes from dorsal root ganglion (drg), trigeminal ganglion (tg), medulla (med), cortex, and spinal cord (sc) showed significantly more differentially expressed genes (degs) in the pns than the cns. |
2023-10-09 |
2023-10-15 |
mouse |
B Guevara, C Montoya, K Brown, E A Mellon, B Spiele. Extended Field Radiosurgery of Spinal Metastases with MRI-Guided Adaptive Planning: A Dosimetric Study. International journal of radiation oncology, biology, physics. vol 117. issue 2S. 2023-10-03. PMID:37784412. |
for example, rtog 0631 was limited to two contiguous levels due to concerns about spinal cord (sc) tolerance when aligning to long targets in the mobile spine. |
2023-10-03 |
2023-10-07 |
Not clear |
Natalia Malek, Jakub Mlost, Magdalena Kostrzewa, Jolanta Rajca, Katarzyna Starowic. Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying Development of Neuropathic Pain Component in the Animal Model of Osteoarthritis. Molecular neurobiology. 2023-09-21. PMID:37731080. |
development of pain phenotype was assessed by behavioral testing (pam test and von frey's test), while corresponding changes in dorsal root ganglia (drgs l3-l5) and spinal cord (sc) gene expression were assessed by means of qrt-pcr technique. |
2023-09-21 |
2023-10-07 |
rat |
Christian Cornelius Arnold, André Toussaint, Frederick Mantel, Michael Flentje, Klaus Bratengeie. Dosimetric evaluation of a spinal cord dose-limiting 3D-CRT technique for radiotherapy of spinal metastases. Journal of applied clinical medical physics. 2023-09-08. PMID:37679969. |
to evaluate the possible advantages of a simple spinal cord (sc) dose-limiting three-dimensional conformal radiotherapy (3d-crt) technique in comparison to conventional two-dimensional (2d) techniques and other 3d-crt techniques for spinal bone irradiation. |
2023-09-08 |
2023-10-07 |
Not clear |
M Ángeles Sánchez Roldán, Dulce Moncho, Kimia Rahnama, Daniela Santa-Cruz, Elena Lainez, Daniel Baiget, Ivette Chocrón, Darío Gándara, Agustín Bescós, Juan Sahuquillo, María A Poc. Intraoperative Neurophysiological Monitoring in Syringomyelia Surgery: A Multimodal Approach. Journal of clinical medicine. vol 12. issue 16. 2023-08-26. PMID:37629243. |
any direct intervention on the syrinx requires a myelotomy, posing a significant risk of iatrogenic spinal cord (sc) injury. |
2023-08-26 |
2023-09-07 |
Not clear |
Orion P Keifer, Juanmarco Gutierrez, Mark T Butt, Sarah D Cramer, Raymond Bartus, Malu Tansey, Daniel Deaver, Alexandre Betourne, Nicholas M Bouli. Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potential new treatment route for amyotrophic lateral sclerosis. PloS one. vol 18. issue 8. 2023-08-22. PMID:37607205. |
in this context, we postulated that continuous intrathecal (it) infusion of low doses of riluzole could provide consistent elevations of the drug spinal cord (sc) concentrations at or above those achieved with oral dosing, without increasing the risk for adverse events associated with systemic drug exposure or off-target side effects in the brain. |
2023-08-22 |
2023-09-07 |
human |
Lucas de M T Branco, Thiago J R Rezende, Fabiano Reis, Marcondes C Franç. Advanced Structural Magnetic Resonance Imaging of the Spinal Cord: Technical Aspects and Clinical Use. Seminars in ultrasound, CT, and MR. 2023-08-15. PMID:37581877. |
for a long time, technical obstacles have hampered the acquisition of high-resolution images and the development of reliable processing protocols for spinal cord (sc) mri. |
2023-08-15 |
2023-09-07 |
Not clear |
Torsten Felske, Chiara Tocco, Sophie Péron, Kawssar Harb, Christian Alfano, Chiara Galante, Benedikt Berninger, Michèle Stude. Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities. PLoS biology. vol 21. issue 8. 2023-08-08. PMID:37552690. |
reprogrammed neurons express dl molecular markers and project toward subcerebral targets, including thalamus, cerebral peduncle (cp), and spinal cord (sc). |
2023-08-08 |
2023-08-16 |
mouse |
Ana Ribeiro, Mariana Rebocho da Costa, Carmen de Sena-Tomás, Elsa Charas Rodrigues, Raquel Quitéria, Tiago Maçarico, Susana Constantino Rosa Santos, Leonor Saúd. Development and repair of blood vessels in the zebrafish spinal cord. Open biology. vol 13. issue 8. 2023-08-08. PMID:37553073. |
unlike mammals, zebrafish can repair the spinal cord (sc) and restore motility, but the vascular response to injury has not been investigated. |
2023-08-08 |
2023-08-16 |
zebrafish |