| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Syamala Rani Thimmiraju, Maria Jose Villar, Jason T Kimata, Ulrich Strych, Maria Elena Bottazzi, Peter J Hotez, Jeroen Polle. Optimization of Cellular Transduction by the HIV-Based Pseudovirus Platform with Pan-Coronavirus Spike Proteins. Viruses. vol 16. issue 9. 2024-09-28. PMID:39339968. |
these findings were applicable across variant spike pseudoviruses that include not only sars-cov-2 variants, but also sars, mers, alpha coronavirus (nl-63), and bat-like coronaviruses. |
2024-09-28 |
2024-10-01 |
Not clear |
| K Saravanan, S Elavarasi, G Revathi, P Karuppannan, M Ashokkumar, C Muthusamy, A Ram Kuma. Targeting SARS-CoV2 spike glycoprotein: molecular insights into phytocompounds binding interactions - Journal of biomaterials science. Polymer edition. 2024-09-03. PMID:39225011. |
targeting sars-cov2 spike glycoprotein: molecular insights into phytocompounds binding interactions - this study utilized small molecular characterization and docking study to evaluate the binding affinity of seven antiviral phytocompounds with the sars cov-2 variants (sars-cov-2 spike glycoprotein, sars-cov-2 spike protein variant in 1-rbd, alpha variant sars-cov2- spike protein). |
2024-09-03 |
2024-09-05 |
Not clear |
| Nandkishor Duragkar, Rupesh Chikhale, Malgorzata Piechota, Chhanda Charan Danta, Pradeep Gandhale, Prakash Itankar, Sonali Chikhale, Nilambari Gurav, Mohd Shahnawaz Khan, Wojciech Pokrzywa, Pankaj Thapa, Richard Bryce, Shailendra Gura. SARS-CoV-2 inhibitory potential of fish oil-derived 2-pyrone compounds by acquiring linoleic acid binding site on the spike protein. International journal of biological macromolecules. 2024-07-04. PMID:38964690. |
molecular docking was studied on the sars cov-2 variants of concern; sars cov-2 wt (pdb: 6vxx), sars cov-2 alpha variant (pdb: 7lws), sars cov-2 delta variant (pdb: 7tou), sars cov-2 gamma variant (pdb: 7v78), sars cov-2 kappa variant (pdb: 7vx9), and sars cov-2 omicron variant (pdb: 7qo7) and tmprss2 (pdb: 7y0e). |
2024-07-04 |
2024-07-11 |
human |
| Hailong Guo, Sha Ha, Jason W Botten, Kai Xu, Ningyan Zhang, Zhiqiang An, William R Strohl, John W Shiver, Tong-Ming F. SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies. Viruses. vol 16. issue 5. 2024-05-25. PMID:38793580. |
in addition, this type of unique ace2-based virus-trapping molecules can counter all zoonotic sars coronaviruses, either from unknown animal hosts or from established wild-life reservoirs of sars-cov-2, and even seasonal alpha coronavirus nl63 that depends on human ace2 for infection. |
2024-05-25 |
2024-05-27 |
human |
| Aslıhan Sahin, Eda Karadag-Oncel, Osman Buyuksen, Yildiz Ekemen-Keles, Gulnihan Ustundag, Aysegul Elvan-Tuz, Selin Tasar, Elif Didinmez-Taskirdi, Muge Baykan, Ahu Kara-Aksay, Nisel Yilmaz, Nihal Olgac-Dundar, Dilek Yilma. The diversity in the clinical features of children hospitalized with COVID-19 during the nonvariant, Alpha (B.1.1.7), Delta (B.1.617.2), and Omicron (B.1.1.529) variant periods of SARS CoV-2: Caution for neurological symptoms in Omicron variant. Journal of medical virology. 2023-03-01. PMID:36856142. |
the diversity in the clinical features of children hospitalized with covid-19 during the nonvariant, alpha (b.1.1.7), delta (b.1.617.2), and omicron (b.1.1.529) variant periods of sars cov-2: caution for neurological symptoms in omicron variant. |
2023-03-01 |
2023-08-14 |
Not clear |
| Dorothea Schmidt, Inamullah Hakeem Said, Nicholas Ohl, Mobinasaddat Sharifii, Paula Cotrell, Nikolai Kuhner. Investigating the interaction between dietary polyphenols, the SARS CoV-2 spike protein and the ACE-2 receptor. Food & function. 2022-06-23. PMID:35734946. |
it could be experimentally shown that 5-caffeoyl quinic acid and epicatechin reduce the binding constant between sars cov-2 spike protein of the alpha variant and the ace-2 receptor by a factor of ten. |
2022-06-23 |
2023-08-14 |
human |
| Osman Özüdoğru, Yasemin Genç Bahçe, Ömer Ace. SARS CoV-2 reinfection rate is higher in the Omicron variant than in the Alpha and Delta variants. Irish journal of medical science. 2022-06-17. PMID:35711013. |
sars cov-2 reinfection rate is higher in the omicron variant than in the alpha and delta variants. |
2022-06-17 |
2023-08-14 |
Not clear |
| Lucie Beranová, Marcin P Joachimiak, Tomáš Kliegr, Gollam Rabby, Vilém Sklená. Why was this cited? Explainable machine learning applied to COVID-19 research literature. Scientometrics. 2022-04-18. PMID:35431364. |
on the other hand, feline (fipv, fcov) and canine coronaviruses (ccov) are in the alpha coronavirus clade and more distant from the betab clade with human sars viruses. |
2022-04-18 |
2023-08-13 |
human |
| Hussein N Ali, Sherko S Niranji, Sirwan M A Al-Ja. Association of tumor necrosis factor alpha -308 single nucleotide polymorphism with SARS CoV-2 infection in an Iraqi Kurdish population. Journal of clinical laboratory analysis. 2022-04-04. PMID:35373411. |
association of tumor necrosis factor alpha -308 single nucleotide polymorphism with sars cov-2 infection in an iraqi kurdish population. |
2022-04-04 |
2023-08-13 |
Not clear |
| Jorge A Vila, Pedro Serrano, Kurt Wüthrich, Harold A Scherag. Sequential nearest-neighbor effects on computed 13Calpha chemical shifts. Journal of biomolecular NMR. vol 48. issue 1. 2010-12-17. PMID:20644980. |
to evaluate sequential nearest-neighbor effects on quantum-chemical calculations of (13)c(alpha) chemical shifts, we selected the structure of the nucleic acid binding (nab) protein from the sars coronavirus determined by nmr in solution (pdb id 2k87). |
2010-12-17 |
2023-08-12 |
Not clear |
| Giampaolo Primofiore, Federico Da Settimo, Anna Maria Marini, Sabrina Taliani, Concettina La Motta, Francesca Simorini, Ettore Novellino, Giovanni Greco, Barbara Cosimelli, Marina Ehlardo, Annalisa Sala, François Besnard, Marina Montali, Claudia Martin. Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides. Journal of medicinal chemistry. vol 49. issue 8. 2006-05-22. PMID:16610792. |
on the basis of published mutagenesis studies and the present sars, we speculate that the s(1) hba/d group might be identified as the hydroxyl of alpha(1)-tyr209 or of other neighboring amino acids. |
2006-05-22 |
2023-08-12 |
rat |
| Yi Ren, Qing-Yu He, Jianqing Fan, Brian Jones, Yuan Zhou, Yi Xie, Chung-Yan Cheung, Adrian Wu, Jen-Fu Chiu, J S Malik Peiris, Paul Kwong Hang Ta. The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome. Proteomics. vol 4. issue 11. 2005-04-13. PMID:15378763. |
by using proteomic technology, truncated forms of alpha(1)-antitrypsin (tf-alpha(1)-at) were found to increase significantly and consistently in sera of sars patients compared to control subjects. |
2005-04-13 |
2023-08-12 |
human |
| Yi Ren, Qing-Yu He, Jianqing Fan, Brian Jones, Yuan Zhou, Yi Xie, Chung-Yan Cheung, Adrian Wu, Jen-Fu Chiu, J S Malik Peiris, Paul Kwong Hang Ta. The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome. Proteomics. vol 4. issue 11. 2005-04-13. PMID:15378763. |
as alpha(1)-at plays an important role in the protection of lung function, its degradation may be an important factor in the pathogenesis of sars. |
2005-04-13 |
2023-08-12 |
human |
| Bojian Zheng, Ming-Liang He, King-Ling Wong, Ching Tung Lum, Leo L M Poon, Ying Peng, Yi Guan, Marie C M Lin, Hsiang-Fu Kun. Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma). Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 24. issue 7. 2005-01-27. PMID:15296649. |
we sought to investigate the anti-severe acute respiratory syndrome (sars)-associated coronavirus (scov) activities of type i (alpha and beta) and type ii (gamma) interferons (ifn) in vitro. |
2005-01-27 |
2023-08-12 |
Not clear |
| Ute Ströher, Antonino DiCaro, Yan Li, James E Strong, Fred Aoki, Frank Plummer, Steven M Jones, Heinz Feldman. Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha. The Journal of infectious diseases. vol 189. issue 7. 2004-05-13. PMID:15031783. |
clinical trials with ifn- alpha might be justified to determine a beneficial effect on the outcome of sars. |
2004-05-13 |
2023-08-12 |
human |
| Ute Ströher, Antonino DiCaro, Yan Li, James E Strong, Fred Aoki, Frank Plummer, Steven M Jones, Heinz Feldman. Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha. The Journal of infectious diseases. vol 189. issue 7. 2004-05-13. PMID:15031783. |
we evaluated the susceptibility of the sars-related coronavirus (sars cov) to ribavirin and interferon (ifn)- alpha in vitro by use of cytopathic effect, plaque assay, and immunoblot analysis. |
2004-05-13 |
2023-08-12 |
human |
| Zhengsheng Zou, Yongping Yang, Jumei Chen, Shaojie Xin, Wei Zhang, Xianzhi Zhou, Yuanli Mao, Liangping Hu, Daojian Liu, Binxia Chang, Weihua Chang, Yanping Liu, Xuemei Ma, Yedong Wang, Xiqing Li. Prognostic factors for severe acute respiratory syndrome: a clinical analysis of 165 cases. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. vol 38. issue 4. 2004-03-02. PMID:14765339. |
during the acute phase of sars, lactate dehydrogenase level, degree of hypoxemia, respiratory rate, alpha -hydroxybutyric dehydrogenase level, creatine kinase isoenzyme-mb, platelet count, and number of involved lobes noted on chest radiographs, and so on, correlated markedly with the prognosis (r=0.257-0.788; p<.05). |
2004-03-02 |
2023-08-12 |
Not clear |
| F Manetti, F Corelli, G Strappaghetti, M Bott. Arylpiperazines with affinity toward alpha(1)-adrenergic receptors. Current medicinal chemistry. vol 9. issue 13. 2002-10-25. PMID:12052168. |
in fact, a large amount of work has been done and reported, describing synthetic procedures, biological evaluation at both alpha(1)-ar and the corresponding subtypes, and structure-activity relationships (sars). |
2002-10-25 |
2023-08-12 |
human |
| Andreas Kling, Gisela Backfisch, Jürgen Delzer, Hervé Geneste, Claudia Graef, Uta Holzenkamp, Wilfried Hornberger, Udo E W Lange, Arnulf Lauterbach, Helmut Mack, Werner Seitz, Thomas Subkowsk. Synthesis and SAR of N-substituted dibenzazepinone derivatives as novel potent and selective alpha(V)beta(3) antagonists. Bioorganic & medicinal chemistry letters. vol 12. issue 3. 2002-06-18. PMID:11814816. |
synthesis and sars of new integrin alpha(v)beta(3) antagonists based on an n-substituted dibenzazepinone scaffold are described. |
2002-06-18 |
2023-08-12 |
Not clear |
| Richard Metz, Mike DiCola, Takao Kurihara, Austin Bailey, Bruce Frank, Bryan Roecklein, Michael Blaes. Mode of action of RNA/DNA oligonucleotides: progress in the development of gene repair as a therapy for alpha(1)-antitrypsin deficiency. Chest. vol 121. issue 3 Suppl. 2002-04-17. PMID:11893721. |
critical to the development of this technology as a therapeutic device for treating genetic disorders, like alpha(1)-antitrypsin deficiency, is the establishment of a standardized assay to study its mode of action and structure-activity relationships (sars). |
2002-04-17 |
2023-08-12 |
Not clear |