| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aurélien Pichon, Philippe Connes, Patricia Quidu, Dominique Marchant, Julien Brunet, Bernard I Levy, José Vilar, Innocent Safeukui, Florence Cymbalista, Maxime Maignan, Jean-Paul Richalet, Fabrice Favre. Acetazolamide and chronic hypoxia: effects on haemorheology and pulmonary haemodynamics. The European respiratory journal. vol 40. issue 6. 2013-05-28. PMID:22523353. |
acetazolamide treatment in hypoxic rats decreased haematocrit (curative by -10% and preventive by -11%), pvr (curative by -36% and preventive by -49%) and right ventricular hypertrophy (preventive -20%), and increased cardiac output (curative by +60% and preventive by +115%). |
2013-05-28 |
2023-08-12 |
rat |
| Aaron B Waxma. Exercise physiology and pulmonary arterial hypertension. Progress in cardiovascular diseases. vol 55. issue 2. 2012-12-11. PMID:23009913. |
in pulmonary artery hypertension (pah)vascular remodeling contributes to a sustained elevation of pulmonary vascular resistance (pvr) and pulmonary artery pressure (pap) as a result of vascular remodeling characterized largely by vascular smooth muscle cell proliferation and medial hypertrophy, and endothelial cell proliferation resulting in lumen obliteration. |
2012-12-11 |
2023-08-12 |
Not clear |
| Ruby A Fernandez, Premanand Sundivakkam, Kimberly A Smith, Amy S Zeifman, Abigail R Drennan, Jason X-J Yua. Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension. Journal of signal transduction. vol 2012. 2012-10-12. PMID:23056939. |
the elevated pvr causes an increase in afterload in the right ventricle, leading to right ventricular hypertrophy, right heart failure, and eventually death. |
2012-10-12 |
2023-08-12 |
Not clear |
| R F Wideman, M E Chapman, K R Hamal, O T Bowen, A G Lorenzoni, G F Erf, N B Anthon. An inadequate pulmonary vascular capacity and susceptibility to pulmonary arterial hypertension in broilers. Poultry science. vol 86. issue 5. 2007-06-12. PMID:17435037. |
the consequences of an inadequate pulmonary vascular capacity have been demonstrated experimentally and include elevated pulmonary vascular resistance (pvr) attributable to noncompliant, fully engorged vascular channels; sustained pulmonary arterial hypertension (pah); systemic hypoxemia and hypercapnia; specific right ventricular hypertrophy, and right atrioventricular valve failure (regurgitation), leading to central venous hypertension and hepatic cirrhosis. |
2007-06-12 |
2023-08-12 |
Not clear |
| D Chemla, V Castelain, P Hervé, Y Lecarpentier, S Brimioull. Haemodynamic evaluation of pulmonary hypertension. The European respiratory journal. vol 20. issue 5. 2003-02-21. PMID:12449189. |
pulmonary hypertension is characterised by the chronic elevation of pulmonary artery pressure (pap) and pulmonary vascular resistance (pvr) leading to right ventricular enlargement and hypertrophy. |
2003-02-21 |
2023-08-12 |
Not clear |
| N Falcon. [Pulmonary hypertension in pediatric heart surgery]. Revista espanola de anestesiologia y reanimacion. vol 48. issue 10. 2002-04-12. PMID:11792301. |
an increase of pvr is due to a combination of vasoconstrictive processes and remodeling, with hypertrophy of the pulmonary artery. |
2002-04-12 |
2023-08-12 |
Not clear |
| D D Ivy, T A Parker, J W Ziegler, H L Galan, J P Kinsella, R M Tuder, S H Abma. Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus. The Journal of clinical investigation. vol 99. issue 6. 1997-04-25. PMID:9077525. |
based on past studies of an experimental model of severe intrauterine pulmonary hypertension, we hypothesized that endothelin-1 (et-1) contributes to high pulmonary vascular resistance (pvr), hypertensive lung structural changes, and right ventricular hypertrophy (rvh) caused by prolonged closure of the ductus arteriosus. |
1997-04-25 |
2023-08-12 |
Not clear |
| P H Pak, L Maughan, K L Baughman, D A Kas. Marked discordance between dynamic and passive diastolic pressure-volume relations in idiopathic hypertrophic cardiomyopathy. Circulation. vol 94. issue 1. 1996-12-09. PMID:8964117. |
dynamic diastolic pressure-volume curves measured during filling (pvr fill) in patients with idiopathic hypertrophic cardiomyopathy (hcm) are often considerably shallower than would be anticipated if one assumed high chamber stiffness. |
1996-12-09 |
2023-08-12 |
Not clear |
| E G Lakatta, J D Cohen, J L Fleg, E D Frohlich, A H Gradma. Hypertension in the elderly: age- and disease-related complications and therapeutic implications. Cardiovascular drugs and therapy. vol 7. issue 4. 1993-12-27. PMID:8241007. |
however, in general, normotensive elderly subjects exhibit the heart and vascular characteristics of "muted" hypertension, including many features of younger hypertensive patients: cardiac hypertrophy, diminution in resting left ventricular early diastolic filling rate, increased arterial stiffness and aortic impedance, diminution in the baroreceptor reflex, a diminished response to catecholamines and diminished renal blood flow, and an increase in peripheral vascular resistance (pvr). |
1993-12-27 |
2023-08-12 |
human |
| G Pinelli, C Longhini, F Portaluppi, G L Manini, P Dominici, A Zuccalà, A Santoro, E Degli Espost. [Different cardiovascular and hormonal consequences of A-V fistula in uremic patients (author's transl)]. Giornale italiano di cardiologia. vol 10. issue 5. 1981-03-27. PMID:7004989. |
in conclusion, an a-v fistula provokes two different hemodynamic behaviours which are related to age, pressure values, myocardial performance, presence of a left ventricular hypertrophy, pvr variations, and renin and nor-adrenalin blood levels. |
1981-03-27 |
2023-08-12 |
Not clear |
| B Meyrick, W Gamble, L Rei. Development of Crotalaria pulmonary hypertension: hemodynamic and structural study. The American journal of physiology. vol 239. issue 5. 1981-01-29. PMID:6449154. |
even later, the larger arteries increase their media as the number of peripheral arteries falls and right ventricular hypertrophy becomes apparent, and hypertension and increased pvr are well established. |
1981-01-29 |
2023-08-12 |
rat |