Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ekkapol Akaraphutiporn, Sumit Durongphongtorn, Katechan Jampachaisri, Patrick Sharp, Cholawat Pacharinsak, Chalika Wangde. Tiletamine/Zolazepam and Ketamine with Dexmedetomidine (TKD) Cocktail Is as Effective as Tiletamine/Zolazepam and Ketamine with Xylazine (TKX) in Providing Pig General Anesthesia. Animals : an open access journal from MDPI. vol 14. issue 19. 2024-10-16. PMID:39409830. |
this study aimed to evaluate dexmedetomidine as an alternative to xylazine in pigs. |
2024-10-16 |
2024-10-18 |
Not clear |
Keely Nicole Wharton, Courtney A Walsh, Marlena Haulter, Dinesh Ekanayake, Dil Ekanayake-Alpe. Sedation Efficacy of Midazolam in Conjunction with Ketamine and Alfaxalone in Female Laboratory Guinea Pigs ( Journal of the American Association for Laboratory Animal Science : JAALAS. 2024-07-30. PMID:39074958. |
however, due to the adverse effects and abuse potential of xylazine, this study explores the possibility of substituting xylazine with midazolam and examines the combined use of midazolam with ketamine and alfaxalone in female laboratory guinea pigs. |
2024-07-30 |
2024-08-02 |
Not clear |
Kelvin C. Buchanan, Robert R. Burge, Gaye R. Rubl. Evaluation of Injectable Anesthetics for Major Surgical Procedures in Guinea Pigs. Contemporary topics in laboratory animal science. vol 37. issue 4. 2019-11-20. PMID:12456147. |
female dunkin hartley guinea pigs that were 9 to 12 weeks old were randomly assigned to receive one of the following anesthetic regimens: ketamine/xylazine (kx), ketamine/detomidine (kd), ketamine/medetomidine (km), 4) tiletaminezolazepam/ xylazine (tx), tiletamine-zolazepam/detomidine (td), or tiletamine-zolazepam/medetomidine (tm). |
2019-11-20 |
2023-08-12 |
Not clear |
Kelvin C. Buchanan, Robert R. Burge, Gaye R. Rubl. Evaluation of Injectable Anesthetics for Major Surgical Procedures in Guinea Pigs. Contemporary topics in laboratory animal science. vol 37. issue 4. 2019-11-20. PMID:12456147. |
a combination of tiletamine-zolazepam and xylazine or medetomidine was effective for inducing anesthesia and providing sufficient analgesia to perform a major surgical procedure on guinea pigs. |
2019-11-20 |
2023-08-12 |
Not clear |
G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Acute effects of general anesthesia with propofol, pentobarbital or isoflurane plus propofol on plasma metabolites and hormones in adult pigs. Journal of animal science. vol 94. issue 12. 2017-05-08. PMID:28046175. |
it was recently shown that the most commonly used sedatives/anesthetics in pigs (e.g., ketamine, xylazine, azaperone) affect physiological responses and thus the primary metabolic readouts have the potential to be confounded. |
2017-05-08 |
2023-08-13 |
Not clear |
Wendy R Williams, Matthew S Johnston, Sarah Higgins, Angelo A Izzo, Lon V Kendal. Blood profiles in unanesthetized and anesthetized guinea pigs (Cavia porcellus). Lab animal. vol 45. issue 1. 2017-04-20. PMID:26684957. |
the authors evaluated hematological and plasma biochemical effects of two anesthetic agents that are commonly used with guinea pigs in a research setting: isoflurane and a combination of ketamine and xylazine. |
2017-04-20 |
2023-08-13 |
human |
Wendy R Williams, Matthew S Johnston, Sarah Higgins, Angelo A Izzo, Lon V Kendal. Blood profiles in unanesthetized and anesthetized guinea pigs (Cavia porcellus). Lab animal. vol 45. issue 1. 2017-04-20. PMID:26684957. |
plasma proteins, liver enzymes, white blood cells and red blood cells appeared to be significantly altered by both anesthetics, and hematological and plasma biochemical differences were greater when guinea pigs were anesthetized with the combination of ketamine and xylazine than when they were anesthetized with isoflurane. |
2017-04-20 |
2023-08-13 |
human |
G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs. Journal of animal science. vol 94. issue 8. 2017-04-11. PMID:27695801. |
effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs. |
2017-04-11 |
2023-08-13 |
Not clear |
G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs. Journal of animal science. vol 94. issue 8. 2017-04-11. PMID:27695801. |
using 6 adult female pigs, we investigated whether selected plasma metabolites and hormones are influenced by ga induced with ketamine (k) and 2 neuroleptic sedatives, namely azaperone (a) and xylazine (x). |
2017-04-11 |
2023-08-13 |
Not clear |
G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs. Journal of animal science. vol 94. issue 8. 2017-04-11. PMID:27695801. |
our data suggest that the effects of azaperone are mediated by cortisol but less so for xylazine, which also indicates that azaperone elicits a stronger stress response in pigs. |
2017-04-11 |
2023-08-13 |
Not clear |
G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs. Journal of animal science. vol 94. issue 8. 2017-04-11. PMID:27695801. |
in conclusion, the neuroleptic sedatives azaperone, and to a lesser extent, xylazine, acutely affect the metabolism of pigs, so primary metabolic readouts obtained under these drugs may be confounded. |
2017-04-11 |
2023-08-13 |
Not clear |
Gabrielle C Musk, Renata S Costa, Jonathan Tuk. Doppler blood pressure measurement in pigs during anaesthesia. Research in veterinary science. vol 97. issue 1. 2015-10-19. PMID:24833268. |
to determine the accuracy of doppler blood pressure measurement in anaesthetised pigs eight large white pigs (sus scrofa) were anaesthetised with zolazepam and tiletamine as zoletil 100 (4 mg/kg) and xylazine (2 mg/kg) by intramuscular injection followed by isoflurane in 100% oxygen. |
2015-10-19 |
2023-08-13 |
Not clear |
De-Zhang Lu, Hong-Gang Fan, Ma Kun, Zhang-Luan Song, Yu-Shi Ming, Jiang Sheng, Hong-Bin Wan. Antagonistic effect of atipamezole, flumazenil and naloxone following anaesthesia with xylazine, tramadol and tiletamine/zolazepam combinations in pigs. Veterinary anaesthesia and analgesia. vol 38. issue 4. 2012-01-05. PMID:21672125. |
antagonistic effect of atipamezole, flumazenil and naloxone following anaesthesia with xylazine, tramadol and tiletamine/zolazepam combinations in pigs. |
2012-01-05 |
2023-08-12 |
Not clear |
Brian R Overholser, Xiaomei Zheng, Carrie Pell, Andrew Blickma. Sudden death in the presence of overt beta-adrenergic receptor activation in guinea pigs immediately following isoflurane anesthesia. Veterinary anaesthesia and analgesia. vol 37. issue 3. 2011-01-21. PMID:20456114. |
of four subsequent guinea pigs anesthetized with the combination of xylazine and ketamine (x/k), three survived isoproterenol implantation for the full 21-day study period while one died perioperatively. |
2011-01-21 |
2023-08-12 |
Not clear |
D-Z Lu, H-G Fan, H-B Wang, K Hu, J-T Zhang, S-M Y. Effect of the addition of tramadol to a combination of tiletamine-zolazepam and xylazine for anaesthesia of miniature pigs. The Veterinary record. vol 167. issue 13. 2010-11-22. PMID:20871083. |
effect of the addition of tramadol to a combination of tiletamine-zolazepam and xylazine for anaesthesia of miniature pigs. |
2010-11-22 |
2023-08-12 |
Not clear |
D-Z Lu, H-G Fan, H-B Wang, K Hu, J-T Zhang, S-M Y. Effect of the addition of tramadol to a combination of tiletamine-zolazepam and xylazine for anaesthesia of miniature pigs. The Veterinary record. vol 167. issue 13. 2010-11-22. PMID:20871083. |
this study investigated the effects of a combination of tiletamine-zolazepam and xylazine plus tramadol (tzxt) and compared the efficacy of this combination with that of tiletaminezolazepam and xylazine (tzx) for providing anaesthesia in chinese experimental miniature pigs. |
2010-11-22 |
2023-08-12 |
Not clear |
J Y Lee, H C Jee, S M Jeong, C S Park, M C Ki. Comparison of anaesthetic and cardiorespiratory effects of xylazine or medetomidine in combination with tiletamine/zolazepam in pigs. The Veterinary record. vol 167. issue 7. 2010-10-20. PMID:20710032. |
comparison of anaesthetic and cardiorespiratory effects of xylazine or medetomidine in combination with tiletamine/zolazepam in pigs. |
2010-10-20 |
2023-08-12 |
Not clear |
R A Ajadi, O F Smith, A F M Makinde, O E Adeley. Increasing ketamine dose enhances the anaesthetic properties of ketamine-xylazine-midazolam combinations in growing pigs. Journal of the South African Veterinary Association. vol 79. issue 4. 2009-06-19. PMID:19496321. |
the influence of increasing the dosage of ketamine on anaesthesia induced by a combination of ketamine, xylazine and midazolam in pigs was determined by assessing the onset of action (oan), duration of analgesia (dan), anaesthesia time (ant), and recovery time (rct) in 10 growing pigs (mean weight: 18.2 +/- 1.65 kg) receiving either 10 mg/kg intramuscular (i.m.) |
2009-06-19 |
2023-08-12 |
Not clear |
M-J Kim, C-S Park, M-H Jun, M-C Ki. Antagonistic effects of yohimbine in pigs anaesthetised with tiletamine/zolazepam and xylazine. The Veterinary record. vol 161. issue 18. 2007-12-13. PMID:17982141. |
antagonistic effects of yohimbine in pigs anaesthetised with tiletamine/zolazepam and xylazine. |
2007-12-13 |
2023-08-12 |
Not clear |
M-J Kim, C-S Park, M-H Jun, M-C Ki. Antagonistic effects of yohimbine in pigs anaesthetised with tiletamine/zolazepam and xylazine. The Veterinary record. vol 161. issue 18. 2007-12-13. PMID:17982141. |
twelve healthy two-month-old landrace x yorkshire pigs of both sexes were randomly assigned to receive either tiletamine and xylazine (zx) or zolazepam and xylazine followed 20 minutes later by yohimbine (zxy). |
2007-12-13 |
2023-08-12 |
Not clear |