| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Wade, T J Hoffmann, K Wigg, J M Jenkin. Association between the oxytocin receptor (OXTR) gene and children's social cognition at 18 months. Genes, brain, and behavior. vol 13. issue 7. 2015-05-22. PMID:24916666. |
association between the oxytocin receptor (oxtr) gene and children's social cognition at 18 months. |
2015-05-22 |
2023-08-13 |
human |
| M Wade, T J Hoffmann, K Wigg, J M Jenkin. Association between the oxytocin receptor (OXTR) gene and children's social cognition at 18 months. Genes, brain, and behavior. vol 13. issue 7. 2015-05-22. PMID:24916666. |
owing to the known effects of oxytocin on adult social cognition and psychopathology, this study hypothesized that variability in the oxytocin receptor gene (oxtr) would be associated with social cognition in children at 18 months. |
2015-05-22 |
2023-08-13 |
human |
| Pedro Vargas-Pinilla, Vanessa Rodrigues Paixão-Côrtes, Pamela Paré, Luciana Tovo-Rodrigues, Carlos Meton de Alencar Gadelha Vieira, Agatha Xavier, David Comas, Alcides Pissinatti, Marialva Sinigaglia, Maurício Menegatti Rigo, Gustavo Fioravanti Vieira, Aldo B Lucion, Francisco Mauro Salzano, Maria Cátira Bortolin. Evolutionary pattern in the OXT-OXTR system in primates: coevolution and positive selection footprints. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 1. 2015-04-23. PMID:25535371. |
this study analyzed oxytocin (oxt) in 29 primate species and the oxytocin receptor (oxtr) in 21 of these species. |
2015-04-23 |
2023-08-13 |
monkey |
| Wei Hung Chang, I Hui Lee, Kao Chin Chen, Mei Hung Chi, Nan-Tsing Chiu, Wei Jen Yao, Ru-Band Lu, Yen Kuang Yang, Po See Che. Oxytocin receptor gene rs53576 polymorphism modulates oxytocin-dopamine interaction and neuroticism traits--a SPECT study. Psychoneuroendocrinology. vol 47. 2015-04-16. PMID:25001970. |
whether the interactions are modulated by oxytocin receptor (oxtr) gene variations remains unclear. |
2015-04-16 |
2023-08-13 |
Not clear |
| Wei Hung Chang, I Hui Lee, Kao Chin Chen, Mei Hung Chi, Nan-Tsing Chiu, Wei Jen Yao, Ru-Band Lu, Yen Kuang Yang, Po See Che. Oxytocin receptor gene rs53576 polymorphism modulates oxytocin-dopamine interaction and neuroticism traits--a SPECT study. Psychoneuroendocrinology. vol 47. 2015-04-16. PMID:25001970. |
considering the dopamine transporter (dat) availability as an endophenotype and the degree of dopamine-mediated neuroticism as a phenotype of the oxtr genotypes, the current molecular imaging study used [(99m)tc]trodat-1 single photon emission computed tomography (spect) to measure the striatal dat availability and the 57-item maudsley personality inventory to measure neuroticism personality traits in healthy individuals to investigate (a) the correlation between the rs53576 (g/a) of oxtr and the striatal dat availability, (b) the correlation between the peripheral oxytocin level and striatal dat availability among different oxtr rs53576 (g/a) genotypes, and (c) whether neuroticism traits could be modified by oxytocin in certain oxtr rs53576 genotypes. |
2015-04-16 |
2023-08-13 |
Not clear |
| Jing Lu, Joshua Reese, Ying Zhou, Emmet Hirsc. Progesterone-induced activation of membrane-bound progesterone receptors in murine macrophage cells. The Journal of endocrinology. vol 224. issue 2. 2015-04-13. PMID:25472814. |
in murine macrophage cells (raw 264.7), activation of mprs by p4 modified to be active only extracellularly by conjugation to bsa (p4bsa, 1.0×10(-7) mol/l) caused a pro-inflammatory shift in the mrna expression profile, with significant upregulation of the expression of cyclooxygenase 2 (cox2 (ptgs2)), il1b, and tnf and downregulation of membrane progesterone receptor alpha (paqr7) and oxytocin receptor (oxtr). |
2015-04-13 |
2023-08-13 |
Not clear |
| Eva Loth, Jean-Baptiste Poline, Benjamin Thyreau, Tianye Jia, Chenyang Tao, Anbarasu Lourdusamy, David Stacey, Anna Cattrell, Sylvane Desrivières, Barbara Ruggeri, Virgile Fritsch, Tobias Banaschewski, Gareth J Barker, Arun L W Bokde, Christian Büchel, Fabiana M Carvalho, Patricia J Conrod, Mira Fauth-Buehler, Herta Flor, Jürgen Gallinat, Hugh Garavan, Andreas Heinz, Ruediger Bruehl, Claire Lawrence, Karl Mann, Jean-Luc Martinot, Frauke Nees, Tomáš Paus, Zdenka Pausova, Luise Poustka, Marcella Rietschel, Michael Smolka, Maren Struve, Jianfeng Feng, Gunter Schuman. Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life events. Biological psychiatry. vol 76. issue 5. 2015-04-07. PMID:24120094. |
common variants in the oxytocin receptor gene (oxtr) have been shown to influence social and affective behavior and to moderate the effect of adverse experiences on risk for social-affective problems. |
2015-04-07 |
2023-08-12 |
human |
| Emily Alves, Andrea Fielder, Nerelle Ghabriel, Michael Sawyer, Femke T A Buisman-Pijlma. Early social environment affects the endogenous oxytocin system: a review and future directions. Frontiers in endocrinology. vol 6. 2015-03-27. PMID:25814979. |
there is increasing evidence that both variations in the oxytocin receptor (oxtr) and concentrations of oxytocin are associated with differences in these functions. |
2015-03-27 |
2023-08-13 |
human |
| Patrick Halbach, De-Ann M Pillers, Nathaniel York, Matti P Asuma, Michelle A Chiu, Wenxiang Luo, Sara Tokarz, Ian M Bird, Bikash R Pattnai. Oxytocin expression and function in the posterior retina: a novel signaling pathway. Investigative ophthalmology & visual science. vol 56. issue 2. 2015-03-24. PMID:25593022. |
its effects are mediated by cell signaling that occurs as a result of oxytocin receptor (oxtr) activation. |
2015-03-24 |
2023-08-13 |
Not clear |
| Yomayra F Guzmán, Natalie C Tronson, Keisuke Sato, Ivana Mesic, Anita L Guedea, Katsuhiko Nishimori, Jelena Radulovi. Role of oxytocin receptors in modulation of fear by social memory. Psychopharmacology. vol 231. issue 10. 2015-02-21. PMID:24287604. |
oxytocin receptors (oxtr) are important mediators of social learning and emotion, with bidirectional effects on fear and anxiety. |
2015-02-21 |
2023-08-12 |
mouse |
| Lynne Sykes, David A MacIntyre, Tiong Ghee Teoh, Phillip R Bennet. Anti-inflammatory prostaglandins for the prevention of preterm labour. Reproduction (Cambridge, England). vol 148. issue 2. 2015-02-19. PMID:24890751. |
nuclear factor kappa b (nfκb) is a transcription factor that controls the expression of many labour-associated genes including ptgs2 (cox2), prostaglandins (pgs) and the oxytocin receptor (oxtr) as well as key inflammatory genes. |
2015-02-19 |
2023-08-13 |
mouse |
| Marit Haram, Martin Tesli, Francesco Bettella, Srdjan Djurovic, Ole Andreas Andreassen, Ingrid Mell. Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders. Frontiers in human neuroscience. vol 9. 2015-02-10. PMID:25667571. |
we performed association analyses between four oxytocin pathway genes (oxt, oxtr, avp, and cd38) and four areas of social behavior-related psychopathology as measured by positive and negative syndrome scale. |
2015-02-10 |
2023-08-13 |
human |
| Marit Haram, Martin Tesli, Francesco Bettella, Srdjan Djurovic, Ole Andreas Andreassen, Ingrid Mell. Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders. Frontiers in human neuroscience. vol 9. 2015-02-10. PMID:25667571. |
our findings indicate that while oxytocin pathway genes do not appear to contribute to the susceptibility to psychotic disorders, variations in the oxtr gene might play a role in the development of impaired social behavior. |
2015-02-10 |
2023-08-13 |
human |
| S M Freeman, H Walum, K Inoue, A L Smith, M M Goodman, K L Bales, L J Youn. Neuroanatomical distribution of oxytocin and vasopressin 1a receptors in the socially monogamous coppery titi monkey (Callicebus cupreus). Neuroscience. vol 273. 2015-02-09. PMID:24814726. |
here, we use receptor autoradiography to identify the distribution of arginine vasopressin 1a receptor (avpr1a) and oxytocin receptors (oxtr) in hemispheres of titi monkey brain (n=5). |
2015-02-09 |
2023-08-13 |
monkey |
| Orna Levran, Matthew Randesi, Yi Li, John Rotrosen, Jurg Ott, Miriam Adelson, Mary Jeanne Kree. Drug addiction and stress-response genetic variability: association study in African Americans. Annals of human genetics. vol 78. issue 4. 2015-01-23. PMID:24766650. |
thirteen snps showed association with cocaine addiction, including the synonymous snps rs237902, in the oxytocin receptor gene (oxtr), and rs5374 in galr1. |
2015-01-23 |
2023-08-13 |
Not clear |
| Benjamin A Tabak, Michael E McCullough, Charles S Carver, Eric J Pedersen, Michael L Cuccar. Variation in oxytocin receptor gene (OXTR) polymorphisms is associated with emotional and behavioral reactions to betrayal. Social cognitive and affective neuroscience. vol 9. issue 6. 2015-01-16. PMID:23547247. |
variation in oxytocin receptor gene (oxtr) polymorphisms is associated with emotional and behavioral reactions to betrayal. |
2015-01-16 |
2023-08-12 |
Not clear |
| Benjamin A Tabak, Michael E McCullough, Charles S Carver, Eric J Pedersen, Michael L Cuccar. Variation in oxytocin receptor gene (OXTR) polymorphisms is associated with emotional and behavioral reactions to betrayal. Social cognitive and affective neuroscience. vol 9. issue 6. 2015-01-16. PMID:23547247. |
variations in the gene that encodes the oxytocin receptor (oxtr) have been associated with many aspects of social cognition as well as several prosocial behaviors. |
2015-01-16 |
2023-08-12 |
Not clear |
| Sara M Freeman, Kiyoshi Inoue, Aaron L Smith, Mark M Goodman, Larry J Youn. The neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta). Psychoneuroendocrinology. vol 45. 2015-01-12. PMID:24845184. |
previous attempts to localize oxytocin receptors (oxtr) in the rhesus macaque brain have failed due to reduced selectivity of radioligands, which in primates bind to both oxtr and the structurally similar vasopressin 1a receptor (avpr1a). |
2015-01-12 |
2023-08-13 |
monkey |
| Megan E Rich, Emily J deCárdenas, Heon-Jin Lee, Heather K Caldwel. Impairments in the initiation of maternal behavior in oxytocin receptor knockout mice. PloS one. vol 9. issue 6. 2015-01-12. PMID:24892749. |
oxytocin (oxt) acting through its single receptor subtype, the oxtr, is important for the coordination of physiology and behavior associated with parturition and maternal care. |
2015-01-12 |
2023-08-13 |
mouse |
| Helle Ruff Laursen, Hartwig Roman Siebner, Tina Haren, Kristoffer Madsen, Rikke Grønlund, Oliver Hulme, Susanne Henningsso. Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy. Frontiers in behavioral neuroscience. vol 8. 2014-12-24. PMID:25538588. |
we investigated the effect of variation in the oxytocin receptor gene (oxtr) and the serotonin transporter gene (slc6a4) on the psychophysical and neurometric variability associated with empathic performance. |
2014-12-24 |
2023-08-13 |
human |