| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steffy B Manjila, Rebecca Betty, Yongsoo Ki. Missing pieces in decoding the brain oxytocin puzzle: Functional insights from mouse brain wiring diagrams. Frontiers in neuroscience. vol 16. 2022-11-17. PMID:36389241. |
the hypothalamic neuropeptide, oxytocin (oxt), has been the focus of research for decades due to its effects on body physiology, neural circuits, and various behaviors. |
2022-11-17 |
2023-08-14 |
mouse |
| Sheena Potretzke, Yangmiao Zhang, Ju Li, Kristopher M Fecteau, David W Erikson, Marcel Hibert, Andrey E Ryabini. Male-selective effects of oxytocin agonism on alcohol intake: behavioral assessment in socially housed prairie voles and involvement of RAGE. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-11-12. PMID:36369481. |
targeting the oxytocin (oxt) peptide system has emerged as a promising new approach for the treatment of alcohol use disorder (aud). |
2022-11-12 |
2023-08-14 |
Not clear |
| Adele Romano, Gustavo Provens. Therapeutic Potential of Targeting the Oxytocinergic System. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36362081. |
the nine amino acid neuropeptide oxytocin (oxt, cys-tyr-ile-gln-asn-cys-pro-leu-gly-nh2) is one of the most studied hormones of the body [...]. |
2022-11-11 |
2023-08-14 |
Not clear |
| Jan A Mennigen, Divya Ramachandran, Katherine Shaw, Radha Chaube, Keerikkattil P Joy, Vance L Trudea. Reproductive roles of the vasopressin/oxytocin neuropeptide family in teleost fishes. Frontiers in endocrinology. vol 13. 2022-10-31. PMID:36313759. |
the vertebrate nonapeptide families arginine vasopressin (avp) and oxytocin (oxt) are considered to have evolved from a single vasopressin-like peptide present in invertebrates and termed arginine vasotocin in early vertebrate evolution. |
2022-10-31 |
2023-08-14 |
Not clear |
| Kengo Inada, Kazoku Tsujimoto, Masahide Yoshida, Katsuhiko Nishimori, Kazunari Miyamich. Oxytocin signaling in the posterior hypothalamus prevents hyperphagic obesity in mice. eLife. vol 11. 2022-10-25. PMID:36281647. |
neural hormone oxytocin (oxt) has received attention in this context because it is produced by neurons in the paraventricular hypothalamic nucleus (pvh), a known output center of hypothalamic regulation of appetite. |
2022-10-25 |
2023-08-14 |
mouse |
| Benjamin Jurek, Lucia Denk, Nicole Schäfer, Mohammad Saied Salehi, Sareh Pandamooz, Silke Haertei. Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping. Frontiers in cellular neuroscience. vol 16. 2022-10-20. PMID:36263085. |
oxytocin (oxt) is a neuropeptide that has been associated with neurological diseases like autism, a strong regulating activity on anxiety and stress-related behavior, physiological effects during pregnancy and parenting, and various cellular effects in neoplastic tissue. |
2022-10-20 |
2023-08-14 |
human |
| Aaron H Wasserman, Amanda R Huang, Yonatan R Lewis-Israeli, McKenna D Dooley, Allison L Mitchell, Manigandan Venkatesan, Aitor Aguirr. Oxytocin promotes epicardial cell activation and heart regeneration after cardiac injury. Frontiers in cell and developmental biology. vol 10. 2022-10-17. PMID:36247002. |
here, we show that oxytocin (oxt), a hypothalamic neuroendocrine peptide, induces epicardial cell proliferation, emt, and transcriptional activity in a model of human induced pluripotent stem cell (hipsc)-derived epicardial cells. |
2022-10-17 |
2023-08-14 |
human |
| Clinton T Elfers, James E Blevins, Therese S Salameh, Elizabeth A Lawson, David Silva, Alex Kiselyov, Christian L Rot. Novel Long-Acting Oxytocin Analog with Increased Efficacy in Reducing Food Intake and Body Weight. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232550. |
oxytocin (oxt) analogues have been designed to overcome the limitation of the short half-life of the native oxt peptide. |
2022-10-14 |
2023-08-14 |
rat |
| Sofia Bergh, Rachel Y Cheong, Åsa Petersén, Sanaz Gaber. Oxytocin in Huntington's disease and the spectrum of amyotrophic lateral sclerosis-frontotemporal dementia. Frontiers in molecular neuroscience. vol 15. 2022-10-03. PMID:36187357. |
oxytocin (oxt) is a neuropeptide known to play a pivotal role in the regulation of social cognition as well as in emotional behaviors such as anxiety and depression. |
2022-10-03 |
2023-08-14 |
human |
| Garriz Angela, Morokuma Junji, Bowman Maytal, Pagni Sarah, Zoukhri Dris. Effects of proinflammatory cytokines on lacrimal gland myoepithelial cells contraction. Frontiers in ophthalmology. vol 2. 2022-09-23. PMID:36147586. |
in a previous study, we demonstrated that lacrimal gland mec express the oxytocin receptor (oxtr) and they contract under oxytocin (oxt) stimulation. |
2022-09-23 |
2023-08-14 |
mouse |
| Lei Guo, Yang-Jian Qi, Hong Tan, Dan Dai, Rawien Balesar, Arja Sluiter, Joop van Heerikhuize, Shao-Hua Hu, Dick F Swaab, Ai-Min Ba. Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients. EBioMedicine. vol 84. 2022-09-20. PMID:36126617. |
oxytocin (oxt) and corticotropin-releasing hormone (crh) are both produced in hypothalamic paraventricular nucleus (pvn). |
2022-09-20 |
2023-08-14 |
mouse |
| Takashi Maruyama, Makiko Shimizu, Naofumi Ikeda, Kazuhiko Baba, Mitsuhiro Yoshimura, Yoichi Uet. Expression of oxytocin in hypothalamus and reduction of nociceptive stress following administration of Kamikihi-to in female rats. Frontiers in pharmacology. vol 13. 2022-09-16. PMID:36110514. |
hypothalamo-neurohypophysial oxytocin (oxt) plays an essential role in reproduction and in several socio-physiological functions, including stress reduction, anxiety relief, feeding suppression, social recognition, and trust building. |
2022-09-16 |
2023-08-14 |
rat |
| Ozge Oztan, Olena Zyga, Diane E J Stafford, Karen J Parke. Linking oxytocin and arginine vasopressin signaling abnormalities to social behavior impairments in Prader-Willi syndrome. Neuroscience and biobehavioral reviews. 2022-09-16. PMID:36113782. |
although the two neuropeptides (i.e., oxytocin [oxt] and arginine vasopressin [avp]) most implicated in mammalian prosocial functioning are of hypothalamic origin, and social functioning is markedly impaired in pws, there has been little consideration of how dysregulation of these neuropeptide signaling pathways may contribute to pws's social behavior impairments. |
2022-09-16 |
2023-08-14 |
Not clear |
| Kazuaki Nishimura, Kiyoshi Yoshino, Naofumi Ikeda, Kazuhiko Baba, Kenya Sanada, Yasuki Akiyama, Haruki Nishimura, Kentaro Tanaka, Satomi Sonoda, Hiromichi Ueno, Mitsuhiro Yoshimura, Takashi Maruyama, Toru Hachisuga, Yoichi Uet. Oestrogen-dependent hypothalamic oxytocin expression with changes in feeding and body weight in female rats. Communications biology. vol 5. issue 1. 2022-09-06. PMID:36064966. |
oxytocin (oxt) is produced in the hypothalamic nuclei and secreted into systemic circulation from the posterior pituitary gland. |
2022-09-06 |
2023-08-14 |
rat |
| Qian Zhuang, Xiaoxiao Zheng, Shuxia Yao, Weihua Zhao, Benjamin Becker, Xiaolei Xu, Keith M Kendric. Oral, similar to intranasal, administration of oxytocin decreases top-down social attention. The international journal of neuropsychopharmacology. 2022-09-02. PMID:36053298. |
the neuropeptide oxytocin (oxt) modulates social cognition by increasing attention towards social cues and may have therapeutic potential for impaired social attention in disorders such as autism. |
2022-09-02 |
2023-08-14 |
Not clear |
| Katrin Elisabeth Giel, Kathrin Schag, Elisabeth Johanna Leehr, Isabelle Mack, Lea-Sarah Schuster, Ariane Wiegand, Stephan Zipfel, Manfred Hallschmid, Vanessa Nieratschke. OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorder. Clinical epigenetics. vol 14. issue 1. 2022-08-30. PMID:36042529. |
the neuropeptide oxytocin (oxt) plays a role in the regulation of eating behavior and metabolism. |
2022-08-30 |
2023-08-14 |
Not clear |
| Katrin Elisabeth Giel, Kathrin Schag, Elisabeth Johanna Leehr, Isabelle Mack, Lea-Sarah Schuster, Ariane Wiegand, Stephan Zipfel, Manfred Hallschmid, Vanessa Nieratschke. OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorder. Clinical epigenetics. vol 14. issue 1. 2022-08-30. PMID:36042529. |
oxt functioning is altered in patients with eating and weight disorders, and a variant of the oxytocin receptor gene (oxtr) has been associated with impulsive eating behavior as it is seen in patients with binge eating disorder (bed). |
2022-08-30 |
2023-08-14 |
Not clear |
| Flávia de Lima Osório, Gleidy Vannesa Espitia-Rojas, Lilian Neto Aguiar-Ric. Effects of intranasal oxytocin on the self-perception and anxiety of singers during a simulated public singing performance: A randomized, placebo-controlled trial. Frontiers in neuroscience. vol 16. 2022-08-29. PMID:36033618. |
considering that oxytocin (oxt) has a potential therapeutic effect on anxiety, cognitive processes, and decreased psychosocial stress, this study's objective was to assess the effects of a single dose of 24 ui of intranasal oxt among professional singers, during a public singing simulation test, on self-rated performance and mood. |
2022-08-29 |
2023-08-14 |
human |
| Christina A Watts, Alexandra Haupt, Jordan Smith, Emily Welch, Aalia Malik, Roman Giacomino, Dinah Walter, Nhlalala Mavundza, Ashley Shemery, Heather K Caldwell, Colleen M Nova. Measuring Skeletal Muscle Thermogenesis in Mice and Rats. Journal of visualized experiments : JoVE. issue 185. 2022-08-15. PMID:35969093. |
provided are demonstrations of this success using predator odor (po; ferret odor) as a contextual stimulus and injections of oxytocin (oxt) as a pharmacological stimulus, where predator odor induces muscle thermogenesis, and oxt suppresses muscle temperature. |
2022-08-15 |
2023-08-14 |
mouse |
| Thomas P Chacko, J Tory Toole, Spencer Richman, Garry L Spink, Matthew J Reinhard, Ryan C Brewster, Michelle E Costanzo, Gordon Broderic. Mapping the network biology of metabolic response to stress in posttraumatic stress disorder and obesity. Frontiers in psychology. vol 13. 2022-08-12. PMID:35959009. |
moreover, oxytocin (oxt), neuropeptide-y (npy), and cortisol supported an almost direct propagation of stress to ptsd and obesity with different net effects. |
2022-08-12 |
2023-08-14 |
Not clear |