Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Angela Gárriz, Salome Aubry, Quentin Wattiaux, Jeffrey Bair, Michael Mariano, Georgios Hatzipetrou, Maytal Bowman, Junji Morokuma, Gustavo Ortiz, Pedram Hamrah, Darlene A Dartt, Driss Zoukhr. Role of the Phospholipase C Pathway and Calcium Mobilization in Oxytocin-Induced Contraction of Lacrimal Gland Myoepithelial Cells. Investigative ophthalmology & visual science. vol 62. issue 14. 2021-12-02. PMID:34812841. |
we reported that oxytocin (oxt), added to freshly prepared lacrimal gland lobules, induced myoepithelial cell (mec) contraction. |
2021-12-02 |
2023-08-13 |
Not clear |
Geumhui Lee, Minjung Yoo. Association of plasma concentrations of oxytocin, vasopressin, and serotonin with docility and friendliness of horses. Domestic animal endocrinology. vol 74. 2021-11-30. PMID:32615507. |
oxytocin (oxt) and vasopressin (avp) have been associated with social interaction and affiliative behavior in animals. |
2021-11-30 |
2023-08-13 |
Not clear |
Remi Kinoshita, Ikko Kozaki, Kazunori Shimizu, Takahiro Shibata, Akihito Ochiai, Hiroyuki Hond. Agonist/Antagonist Activity of Oxytocin Variants Obtained from Free Cyclic Peptide Libraries Generated via Amino Acid Substitution. ACS omega. vol 6. issue 46. 2021-11-30. PMID:34841168. |
variants of the cyclic nonapeptide oxytocin (oxt) were synthesized via residue substitution. |
2021-11-30 |
2023-08-13 |
Not clear |
Elena V Kozlova, Matthew C Valdez, Maximillian E Denys, Anthony E Bishay, Julia M Krum, Kayhon M Rabbani, Valeria Carrillo, Gwendolyn M Gonzalez, Gregory Lampel, Jasmin D Tran, Brigitte M Vazquez, Laura M Anchondo, Syed A Uddin, Nicole M Huffman, Eduardo Monarrez, Duraan S Olomi, Bhuvaneswari D Chinthirla, Richard E Hartman, Prasada Rao S Kodavanti, Gladys Chompre, Allison L Phillips, Heather M Stapleton, Bernhard Henkelmann, Karl-Werner Schramm, Margarita C Curras-Collaz. Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. Archives of toxicology. 2021-11-26. PMID:34687351. |
moreover, f1 l-de-71 displayed downregulated mrna transcripts for oxytocin (oxt) in the bed nucleus of the stria terminalis (bnst) and supraoptic nucleus, and vasopressin (avp) in the bnst and upregulated avp1ar in bnst, and oxtr in the paraventricular nucleus. |
2021-11-26 |
2023-08-13 |
mouse |
Kazunori Sasaki, Farhana Ferdousi, Satoshi Fukumitsu, Hidetoshi Kuwata, Hiroko Isod. Antidepressant- and anxiolytic-like activities of Rosmarinus officinalis extract in rodent models: Involvement of oxytocinergic system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 144. 2021-11-24. PMID:34653760. |
oxytocin (oxt), a neuropeptide involved in mammal reproductive and prosocial behaviors, has been reported to interact with various stressor-provoked neurobiological changes, including neuroendocrine, neurotransmitter, and inflammatory processes. |
2021-11-24 |
2023-08-13 |
Not clear |
Yoichi Uet. Transgenic approaches to opening up new fields of vasopressin and oxytocin research. Journal of neuroendocrinology. vol 33. issue 11. 2021-11-24. PMID:34713515. |
transgenic approaches have been applied to generate transgenic rats that express exogenous genes in arginine vasopressin (avp)- and oxytocin (oxt)-producing magnocellular neurosecretory cells (mncs) of the hypothalamic-neurohypophyseal system (hns). |
2021-11-24 |
2023-08-13 |
rat |
Shahein Momenabadi, Abbas Ali Vafaei, Ahmad Reza Bandegi, Mahdi Zahedi-Khorasani, Zohreh Mazaheri, Abedin Vakil. Oxytocin Reduces Brain Injury and Maintains Blood-Brain Barrier Integrity After Ischemic Stroke in Mice. Neuromolecular medicine. vol 22. issue 4. 2021-11-23. PMID:32918238. |
the present study was designed to determine the effect of different doses of oxytocin (oxt) on neuronal injury, spatial memory, blood-brain barrier (bbb) integrity and to explore possible underlying molecular mechanisms in the early stage of stroke in mice. |
2021-11-23 |
2023-08-13 |
mouse |
Ana Rita Nunes, Michael Gliksberg, Susana A M Varela, Magda Teles, Einav Wircer, Janna Blechman, Giovanni Petri, Gil Levkowitz, Rui F Oliveir. Developmental Effects of Oxytocin Neurons on Social Affiliation and Processing of Social Information. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 42. 2021-11-23. PMID:34470805. |
much research has implicated the neuropeptide oxytocin (oxt) in acute modulation of various aspects of social behaviors across vertebrate species, and oxt signaling is associated with the developmental social deficits observed in autism spectrum disorders (asds); however, little is known about the role of oxt in the neurodevelopment of the social brain. |
2021-11-23 |
2023-08-13 |
zebrafish |
Keerthi Thirtamara Rajamani, Amanda B Leithead, Michelle Kim, Marie Barbier, Michael Peruggia, Kristi Niblo, Lara Barteczko, Arthur Lefevre, Valery Grinevich, Hala Harony-Nicola. Efficiency of cell-type specific and generic promoters in transducing oxytocin neurons and monitoring their neural activity during lactation. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:34795340. |
hypothalamic oxytocin (oxt) and arginine-vasopressin (avp) neurons have been at the center of several physiological and behavioral studies. |
2021-11-22 |
2023-08-13 |
rat |
Shota Nishitani, Takashi X Fujisawa, Daiki Hiraoka, Kai Makita, Shinichiro Takiguchi, Shoko Hamamura, Akiko Yao, Koji Shimada, Alicia K Smith, Akemi Tomod. A multi-modal MRI analysis of brain structure and function in relation to OXT methylation in maltreated children and adolescents. Translational psychiatry. vol 11. issue 1. 2021-11-21. PMID:34789725. |
we assessed differences in salivary dna methylation of the gene encoding oxytocin (oxt) between cm (n = 24) and non-cm (n = 31), alongside its impact on brain structures and functions using multi-modal brain imaging (voxel-based morphometry, diffusion tensor imaging, and task and resting-state functional magnetic resonance imaging). |
2021-11-21 |
2023-08-13 |
Not clear |
Kengo Horie, Katsuhiko Nishimor. CRISPR/Cas9-Mediated Genetic Engineering to Generate a Disease Model Prairie Vole, Based on Species-Optimized Assisted Reproductive Technology. Methods in molecular biology (Clifton, N.J.). vol 2384. 2021-11-19. PMID:34550573. |
recent studies of prairie voles have highlighted the importance of oxytocin (oxt) and oxytocin receptor (oxtr)-mediated mechanisms in the regulation of these behaviors.recently, we established assisted reproductive technologies for prairie voles, and successfully and efficiently generated an oxtr gene knockout (ko) prairie vole using clustered regularly interspaced short palindromic repeats (crispr)/crispr-associated protein 9 (cas9 ), a powerful genome editing tool with artificially developed single-strand guide rnas (sgrna) and cas9 endonucleases.herein, we describe the method for crispr /cas9-mediated generation of oxtr ko prairie vole. |
2021-11-19 |
2023-08-13 |
mouse |
Congcong Liu, Chunmei Lan, Keshuang Li, Feng Zhou, Shuxia Yao, Lei Xu, Ning Yang, Xinqi Zhou, Jiaxin Yang, Xue Yong, Yina Ma, Dirk Scheele, Keith M Kendrick, Benjamin Becke. Oxytocinergic Modulation of Threat-Specific Amygdala Sensitization in Humans Is Critically Mediated by Serotonergic Mechanisms. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 6. issue 11. 2021-11-18. PMID:33894423. |
overarching conceptualizations propose that the complex social-emotional effects of oxytocin (oxt) in humans are partly mediated by interactions with other neurotransmitter systems. |
2021-11-18 |
2023-08-13 |
Not clear |
Hidehisa Saito, Shizu Hidema, Ayano Otsuka, Jun Suzuki, Michio Kumagai, Akihiro Kanaya, Toru Murakami, Yusuke Takei, Kazutomo Saito, Shigekazu Sugino, Hiroaki Toyama, Ryuta Saito, Teiji Tominaga, Katsuhiko Nishimori, Masanori Yamauch. Effects of oxytocin on responses to nociceptive and non-nociceptive stimulation in the upper central nervous system. Biochemical and biophysical research communications. vol 574. 2021-11-18. PMID:34419875. |
we aimed to investigate the effect of oxytocin at the supraspinal level in vivo using c57bl/6j (wild-type [wt]), oxytocin-deficient (oxt |
2021-11-18 |
2023-08-13 |
Not clear |
Valentina Gigliucci, Jasper Teutsch, Marc Woodbury-Smith, Mirko Luoni, Marta Busnelli, Bice Chini, Abhishek Banerje. Region-Specific KCC2 Rescue by rhIGF-1 and Oxytocin in a Mouse Model of Rett Syndrome. Cerebral cortex (New York, N.Y. : 1991). 2021-11-18. PMID:34791112. |
to this end, the neuropeptide oxytocin (oxt) is promising, as it also critically modulates kcc2 function during early postnatal development. |
2021-11-18 |
2023-08-13 |
mouse |
Amanda B Leithead, Jeffrey G Tasker, Hala Harony-Nicola. The interplay between glutamatergic circuits and oxytocin neurons in the hypothalamus and its relevance to neurodevelopmental disorders. Journal of neuroendocrinology. 2021-11-17. PMID:34786775. |
oxytocin (oxt) neurons of the hypothalamus are at the center of several physiological functions, including milk ejection, uterus contraction, and maternal and social behavior. |
2021-11-17 |
2023-08-13 |
rat |
Evandro Valentim-Lima, José Antônio Cortes de Oliveira, Jose Antunes-Rodrigues, Luis Carlos Reis, Norberto Garcia-Cairasco, Andre S Mecaw. Neuroendocrine changes in the hypothalamic-neurohypophysial system in the Wistar audiogenic rat (WAR) strain submitted to audiogenic kindling. Journal of neuroendocrinology. vol 33. issue 7. 2021-11-16. PMID:33942400. |
although some studies have reported that hypothalamic-hypophysis function is also altered in war through modulating vasopressin (avp) and oxytocin (oxt) secretion, the role of these neuropeptides in epilepsy still is controversial. |
2021-11-16 |
2023-08-13 |
rat |
Mariana Fortunata Donadon, Rocio Martin-Santos, Flávia L Osóri. Oxytocin effects on the cognition of women with postpartum depression: A randomized, placebo-controlled clinical trial. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:32937192. |
oxytocin (oxt) was shown to have therapeutic properties associated with the promotion of affiliative and pro-social behaviors in different mental disorders. |
2021-11-11 |
2023-08-13 |
Not clear |
Masatoshi Nagano, Fumihito Saitow, Shinpei Higo, Makoto Uzuki, Yasunori Mikahara, Toshio Akimoto, Hitoshi Ozawa, Katsuhiko Nishimori, Hidenori Suzuk. Cesarean section delivery is a risk factor of autism-related behaviors in mice. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:33903690. |
here, using three approaches, we showed experimentally that c/s delivery induced asd-like traits in offspring mice, and that some of these changes were ameliorated by one-time oxytocin (oxt) treatment. |
2021-11-11 |
2023-08-13 |
mouse |
Sylvia Dimitriadou, Eduarda M Santos, Darren P Croft, Ronny van Aerle, Indar W Ramnarine, Amy L Filby, Safi K Darde. Social partner cooperativeness influences brain oxytocin transcription in Trinidadian guppies (Poecilia reticulata). Behavioural brain research. 2021-11-10. PMID:34757109. |
here, we quantify the neuroregulatory response of trinidadian guppies (poecilia reticulata) experiencing cooperation or defection by examining the transcriptional response of the oxytocin gene (oxt; also known as isotocin), which has been implicated in cooperative decision-making. |
2021-11-10 |
2023-08-13 |
Not clear |
Luisa Demarchi, Jodi L Pawluski, Oliver J Bosc. The brain oxytocin and corticotropin-releasing factor systems in grieving mothers: What we know and what we need to learn. Peptides. vol 143. 2021-11-09. PMID:34091013. |
in this review, we present evidence for the involvement of the brain oxytocin (oxt) and corticotropin-releasing factor (crf) systems, which both play a role in maternal behavior and the stress response, in the neurobiology of grief in mothers from a behavioral and molecular point of view. |
2021-11-09 |
2023-08-13 |
human |