| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tae Ui Hong, Seong Kook Par. The Roles of Vascular Endothelial Growth Factor, Angiostatin, and Endostatin in Nasal Polyp Development. Journal of rhinology : official journal of the Korean Rhinologic Society. vol 29. issue 2. 2024-12-12. PMID:39665059. |
microvascular remodeling and angiogenesis are elements of tissue remodeling characteristic of chronic inflammatory diseases, including nasal polyps (nps). |
2024-12-12 |
2024-12-14 |
Not clear |
| Tatsuya Nagan. Biologics treatment for eosinophilic chronic rhinosinusitis complicated by bronchial asthma: Narrative review. Respiratory investigation. vol 63. issue 1. 2024-12-03. PMID:39626320. |
there are 4 subtypes of chronic rhinosinusitis (crs): eosinophilic crs with nasal polyps (ecrswnp), ecrs without nps (ecrssnp), non-ecrswnp, and non-ecrssnp. |
2024-12-03 |
2024-12-06 |
Not clear |
| Samer Adwan, Teiba Obeidi, Faisal Al-Akayle. Chitosan Nanoparticles Embedded in In Situ Gel for Nasal Delivery of Imipramine Hydrochloride: Short-Term Stage Development and Controlled Release Evaluation. Polymers. vol 16. issue 21. 2024-11-15. PMID:39518270. |
this study aimed to explore a novel non-invasive nasal delivery system using chitosan nanoparticles (cs nps) embedded in an in situ gel to address the limitations of oral imp administration. |
2024-11-15 |
2024-11-17 |
Not clear |
| Naruhito Iwasaki, Julie A Poposki, Masanori Kidoguchi, Aiko Oka, Aiko I Klingler, Whitney W Stevens, Lydia A Suh, Junqin Bai, Anju T Peters, Leslie C Grammer, Kevin C Welch, Stephanie S Smith, David B Conley, Bruce S Bochner, Robert P Schleimer, Robert C Kern, Bruce K Tan, Atsushi Kat. Analysis of human neutrophils from nasal polyps by single-cell RNA sequencing reveals roles of neutrophils in chronic rhinosinusitis. The Journal of allergy and clinical immunology. 2024-11-10. PMID:39522652. |
recent studies, including our own, suggest that neutrophils are also elevated in t2 nasal polyps (nps) and that elevated neutrophils display an activated phenotype. |
2024-11-10 |
2024-11-17 |
human |
| Sven F Seys, Sven Schneider, Joost de Kinderen, Sietze Reitsma, Carlo Cavaliere, Peter-Valentin Tomazic, Christina Morgenstern, Geoffrey Mortuaire, Martin Wagenmann, Giulia Bettio, Andrea Ciofalo, Zuzana Diamant, Julia Eckl-Dorna, Wytske J Fokkens, Clemens Holzmeister, Gert Mariën, Simonetta Masieri, Josje Otten, Kathrin Scheckenbach, Aldine Tu, Claus Bacher. Real-world effectiveness of dupilumab in a European cohort of CRSwNP (CHRINOSOR). The Journal of allergy and clinical immunology. 2024-11-01. PMID:39486595. |
pivotal studies with dupilumab demonstrated clinically relevant improvements in nasal polyp score (nps), symptom and quality of life scores in patients with chronic rhinosinusitis with nasal polyps (crswnp). |
2024-11-01 |
2024-11-05 |
Not clear |
| Leandro Azevedo Camargo, Angela Adamski da Silva Reis, Stela Oliveira Rodrigues, Rodrigo da Silva Santos, Melissa Ameloti Gomes Avelin. The Effects of Biomedicines. vol 12. issue 10. 2024-10-26. PMID:39457695. |
the effects of nasal polyps (nps) are usually part of chronic rhinosinusitis with nasal polyposis (crswnp). |
2024-10-26 |
2024-10-29 |
Not clear |
| Lifeng Gao, Yuguang Meng, Xiaowen Luo, Jiangyuan Chen, Xuxia Wan. ZnO Nanoparticles-Induced MRI Alterations to the Rat Olfactory Epithelium and Olfactory Bulb after Intranasal Instillation. Toxics. vol 12. issue 10. 2024-10-26. PMID:39453144. |
we detected 20-nm zno nps biotoxicity following nasal exposure utilizing the non-invasive and real-time magnetic resonance imaging (mri) technique. |
2024-10-26 |
2024-10-28 |
rat |
| Amber U Luong, Joshua M Levy, Ludger Klimek, Richard J Harvey, Jared Silver, Steven G Smith, Abby Fuller, Robert Chan, Peter W Helling. Peak nasal inspiratory flow assessment of polyp size and response from SYNAPSE. The journal of allergy and clinical immunology. Global. vol 3. issue 4. 2024-10-09. PMID:39380981. |
in the phase iii synapse study, mepolizumab plus standard of care reduced total endoscopic nasal polyp score (nps) versus that with placebo in patients with chronic rhinosinusitis with nasal polyps. |
2024-10-09 |
2024-10-11 |
Not clear |
| Basant A Abou-Taleb, Wessam F El-Hadidy, Inas M Masoud, Noura A Matar, Hoda S Hussei. Dihydroquercetin nanoparticles nasal gel is a promising formulation for amelioration of Alzheimer's disease. International journal of pharmaceutics. 2024-10-09. PMID:39384026. |
the goal of the study was to create dihydroquercetin-loaded-chitosan nanoparticles (dhq-cs nps) loaded to a mucoadhesive, thermosensitive in-situ gel for direct nasal administration to cure alzheimer's disorder. |
2024-10-09 |
2024-10-12 |
rat |
| Basant A Abou-Taleb, Wessam F El-Hadidy, Inas M Masoud, Noura A Matar, Hoda S Hussei. Dihydroquercetin nanoparticles nasal gel is a promising formulation for amelioration of Alzheimer's disease. International journal of pharmaceutics. 2024-10-09. PMID:39384026. |
histopathologically, the dhq-cs nps nasal gel produced improvement in the hippocampal and cerebral cortex structures, being comparable to the normal group. |
2024-10-09 |
2024-10-12 |
rat |
| Tina Mauthe, Fabio S Ryser, Catrin Brühlmann, Ayla Yalamanoglu, Christian Meerwein, Urs C Steiner, Michael B Soyk. Correlation of sino-nasal outcome test and nasal polyp score in dupilumab-treated chronic rhinosinusitis with nasal polyps. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2024-09-21. PMID:39306591. |
this study aimed to assess changes in nasal polyp score (nps) and sino-nasal outcome test (snot) scores in chronic rhinosinusitis with nasal polyps (crswnp) patients undergoing dupilumab treatment and explore correlations between these scores. |
2024-09-21 |
2024-09-24 |
Not clear |
| Axel Nordström, Mattias Jangard, Michael Ryott, Xiao Tang, Marie Svedberg, Maria Kumli. Mucosal LTE Prostaglandins & other lipid mediators. 2024-08-23. PMID:39179198. |
mucosal lte altered biosynthesis of eicosanoids is linked to type 2 inflammation in chronic rhinosinusitis with nasal polyps (crswnp), but their role in recalcitrant nps is unclear. |
2024-08-23 |
2024-08-27 |
Not clear |
| Jonathan A Bernstein, Jared Silver, Elizabeth Packnett, Carolyn R Lew, Yvonne Robles, Arijita De. Real-world unified airway benefits of mepolizumab: Effectiveness in patients with asthma and comorbid nasal polyps. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2024-07-27. PMID:38972449. |
nasal polyps (nps) are commonly associated with chronic rhinosinusitis (crs). |
2024-07-27 |
2024-07-29 |
Not clear |
| Jason S Chwa, Minjun Kim, Yesun Lee, Wesley A Cheng, Yunho Shin, Jaycee Jumarang, Jeffrey M Bender, Pia S Pannara. Detection of SARS-CoV-2-Specific Secretory IgA and Neutralizing Antibodies in the Nasal Secretions of Exposed Seronegative Individuals. Viruses. vol 16. issue 6. 2024-06-27. PMID:38932145. |
of the 36 exposed individuals without sars-cov-2 detected by the rt-pcr of nps specimens and seronegative for sars-cov-2-specific igg at enrollment and convalescence, 13 (36.1%) had positive sars-cov-2-specific siga levels detected in the nasal mucosa at enrollment. |
2024-06-27 |
2024-06-29 |
human |
| Jing Pei, Zhaoran Ding, Cheng Jiao, Ying Tao, Huifen Yang, Jing L. Autophagy in chronic rhinosinusitis with or without nasal polyps. Frontiers in cell and developmental biology. vol 12. 2024-06-27. PMID:38933334. |
while the role of autophagy in asthma has been extensively studied in airway inflammatory diseases, its significance in crs with or without nasal polyps (nps), a condition closely linked to asthma pathophysiology, has also garnered attention, albeit with conflicting findings across studies. |
2024-06-27 |
2024-06-29 |
human |
| Xiangmin Zhou, Qian Zhang, Yuzhu Wan, Li Sh. Up-regulation of systemic and local BDNF in non-allergic Nasal Polyps in China. Pakistan journal of medical sciences. vol 40. issue 5. 2024-06-03. PMID:38827877. |
although the role of brain-derived neurotrophic factor (bdnf) in allergic rhinitis and/or nasal polyps (nps) development has been studied, the contribution of bdnf in non-allergic nps has not been evaluated yet. |
2024-06-03 |
2024-06-05 |
Not clear |
| Sandrine Lefeuvre, Camille Richeval, Jeremy Lelong, Nicolas Venisse, Luc Humbert, Bertrand Brune. N-ethylhexedrone: a very long and bad trip! A Case series. Journal of analytical toxicology. 2024-05-25. PMID:38794952. |
while recovering from the drug effects, 12 to 24 hours after nasal intake of new psychoactive substance (nps), the patients described the following disorders: anxiety, feelings of persecution, asthenia, anhedonia, abulia, psychomotor slowing, and loss of consciousness. |
2024-05-25 |
2024-05-27 |
Not clear |
| Vincenzo Fiorentino, Maurizio Martini, Cosimo Galletti, Cristina Pizzimenti, Mariausilia Franchina, Antonio Ieni, Guido Fadda, Bruno Galletti, Giovanni Tuccar. The Morphology of Nasal Polyps in Different Age Groups: Histopathological Features. Journal of personalized medicine. vol 14. issue 4. 2024-04-27. PMID:38673041. |
nasal polyps (nps) represent the end-stage manifestation of chronic rhinosinusitis (crs), a relatively common pathological condition encountered in all ages of life. |
2024-04-27 |
2024-04-29 |
Not clear |
| Matteo Gelardi, Rossana Giancaspro, Vitaliano Nicola Quaranta, Emanuel La Gatta, Annamaria Ruzza, Michele Cassan. Dupilumab's impact on nasal citology: Real life experience after 1 year of treatment. American journal of otolaryngology. vol 45. issue 4. 2024-04-04. PMID:38574514. |
however, in most studies, the response to treatment is evaluated in terms of improvement in nasal polyp score (nps) or in sino-nasal outcome test (snot-22) scores. |
2024-04-04 |
2024-04-07 |
Not clear |
| Jiunn-Min Shieh, Yih-Jeng Tsai, Ming-Chieh Ma, Chih-Li Chen, Wen-Bin W. The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555391. |
chronic rhinosinusitis (crs) can be traditionally classified as crswnp [with nasal polyps (nps)] and crssnp (without nps) based on the clinical phenotypes but recently suggested to be classified by the endotypes. |
2024-03-30 |
2024-04-02 |
human |