| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Pelosi, M Volante, M Papotti, A Sonzogni, M Masullo, G Vial. Peptide receptors in neuroendocrine tumors of the lung as potential tools for radionuclide diagnosis and therapy. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... vol 50. issue 4. 2007-04-04. PMID:17043625. |
in this paper, the structural and functional aspects and the clinical applications of the detection of several peptide receptors in pulmonary neuroendocrine tumors will be reviewed, including somatostatin receptors, vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide family receptors, cholecystokinin /gastrin receptors, bombesin/gastrin releasing peptide receptors, neurotensin receptors, substance p receptors, neuroepeptide y receptors, calcitonin/calcitonin gene-related peptide receptors, atrial natriuretic peptide receptors, glucagon-like-peptide-1 receptors, oxytocin receptors and endothelin receptors. |
2007-04-04 |
2023-08-12 |
Not clear |
| Vincent Geene. Thymus-dependent T cell tolerance of neuroendocrine functions: principles, reflections, and implications for tolerogenic/negative self-vaccination. Annals of the New York Academy of Sciences. vol 1088. 2007-03-05. PMID:17192574. |
some self-antigens (oxytocin, neurotensin, insulin-like growth factor 2 [igf-2]) have been selected to be predominantly expressed in thymic epithelium and to be presented to thymus t cells for educating them to tolerate other antigens related to them. |
2007-03-05 |
2023-08-12 |
Not clear |
| Natsuko Tsujino, Akihiro Yamanaka, Kanako Ichiki, Yo Muraki, Thomas S Kilduff, Ken-ichi Yagami, Satoru Takahashi, Katsutoshi Goto, Takeshi Sakura. Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 32. 2006-02-21. PMID:16093397. |
using transgenic mice in which orexin neurons specifically express yellow cameleon 2.1, we screened for factors that affect the activity of orexin neurons (a total of 21 peptides and six other factors were examined) and found that a sulfated octapeptide form of cholecystokinin (cck-8s), neurotensin, oxytocin, and vasopressin activate orexin neurons. |
2006-02-21 |
2023-08-12 |
mouse |
| Makoto Sumitomo, Ruoqian Shen, David M Nanu. Involvement of neutral endopeptidase in neoplastic progression. Biochimica et biophysica acta. vol 1751. issue 1. 2005-09-27. PMID:16054017. |
this enzyme cleaves peptide bonds on the amino side of hydrophobic amino acids and inactivates a variety of physiologically active peptides, including atrial natriuretic factor, substance p, bradykinin, oxytocin, leu- and met-enkephalins, neurotensin, bombesin, endothelin-1, and bombesin-like peptides. |
2005-09-27 |
2023-08-12 |
Not clear |
| L E Johnstone, G Leng, C H Brow. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. Journal of neuroendocrinology. vol 16. issue 7. 2004-09-21. PMID:15214863. |
neurotensin increases the firing rate of supraoptic nucleus oxytocin and vasopressin neurones in vitro and induces fos protein expression in the supraoptic nucleus in vivo. |
2004-09-21 |
2023-08-12 |
rat |
| L E Johnstone, G Leng, C H Brow. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. Journal of neuroendocrinology. vol 16. issue 7. 2004-09-21. PMID:15214863. |
here, we used extracellular single-unit electrophysiological recording combined with local microdialysis administration of neurotensin (1 mm at 2 micro l/min) to investigate the effects of locally applied neurotensin on the firing of oxytocin and vasopressin neurones in urethane-anaesthetized virgin and lactating rats. |
2004-09-21 |
2023-08-12 |
rat |
| L E Johnstone, G Leng, C H Brow. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. Journal of neuroendocrinology. vol 16. issue 7. 2004-09-21. PMID:15214863. |
neurotensin decreased the mean firing rate of oxytocin cells in virgin, but not lactating, rats. |
2004-09-21 |
2023-08-12 |
rat |
| L E Johnstone, G Leng, C H Brow. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. Journal of neuroendocrinology. vol 16. issue 7. 2004-09-21. PMID:15214863. |
by contrast to oxytocin cells, neurotensin increased the mean firing rate of vasopressin cells in both virgin and lactating rats, but did not alter the index of dispersion. |
2004-09-21 |
2023-08-12 |
rat |
| L E Johnstone, G Leng, C H Brow. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. Journal of neuroendocrinology. vol 16. issue 7. 2004-09-21. PMID:15214863. |
thus, neurotensin has differential effects on activity patterning in oxytocin and vasopressin cells and the effects on oxytocin cells, but not vasopressin cells, depend upon the physiological status of the animal. |
2004-09-21 |
2023-08-12 |
rat |
| L E Johnstone, G Leng, C H Brow. Effects of neurotensin on the organization of activity in supraoptic nucleus cells in virgin and lactating rats. Journal of neuroendocrinology. vol 16. issue 7. 2004-09-21. PMID:15214863. |
the increase in the variability of firing of oxytocin cells induced by neurotensin in virgin rats, but not in lactating rats, suggests that neurotensin (or other neurotransmitters/neuromodulators with similar actions) might establish conditions that predispose oxytocin cells to fire in milk-ejection bursts in lactating rats. |
2004-09-21 |
2023-08-12 |
rat |
| Robert Root-Bernstei. Molecular complementarity III. peptide complementarity as a basis for peptide receptor evolution: a bioinformatic case study of insulin, glucagon and gastrin. Journal of theoretical biology. vol 218. issue 1. 2002-11-06. PMID:12297071. |
thirteen peptides, 10 of which are not known to self-aggregate (amylin, acth, lhrh, angiotensin ii, atrial natriuretic peptide, somatostatin, oxytocin, neurotensin, vasopressin, and substance p), and three that are known to self-aggregate (insulin, glucagon, and gastrin), were chosen. |
2002-11-06 |
2023-08-12 |
Not clear |
| J Irazusta, P F Silveira, J Gil, A Varona, L Casi. Effects of hydrosaline treatments on prolyl endopeptidase activity in rat tissues. Regulatory peptides. vol 101. issue 1-3. 2002-02-07. PMID:11495689. |
prolyl endopeptidase is known to hydrolyze several peptides, which act on hydromineral balance, such as angiotensins, bradykinin, vasopressin, oxytocin, thyrotropin-releasing hormone, neurotensin and opioids. |
2002-02-07 |
2023-08-12 |
rat |
| M Maes, P Monteleone, R Bencivenga, F Goossens, M Maj, D van West, E Bosmans, S Scharp. Lower serum activity of prolyl endopeptidase in anorexia and bulimia nervosa. Psychoneuroendocrinology. vol 26. issue 1. 2000-12-28. PMID:11070331. |
substrates of pep are, amongst others, neuroactive peptides, such as arginine vasopressin, luteinizing hormone-releasing hormone, thyrotropin releasing hormone,alpha-melanocyte secreting hormone, substance p, oxytocin, bradykinin, neurotensin and angiotensin (ag) i and ii. |
2000-12-28 |
2023-08-12 |
Not clear |
| A Chen, O Laskar-Levy, Y Koc. Selective expression of neuropeptides in the rat mammary gland: somatostatin gene is expressed during lactation. Endocrinology. vol 140. issue 12. 1999-12-20. PMID:10579358. |
we have used specific primers for the following neuropeptides: galanin, somatostatin, vasoactive intestinal peptide, trh, gh-releasing hormone, cholecystokinin, neurotensin, oxytocin, and relaxin. |
1999-12-20 |
2023-08-12 |
rat |
| M Palkovit. Interconnections between the neuroendocrine hypothalamus and the central autonomic system. Geoffrey Harris Memorial Lecture, Kitakyushu, Japan, October 1998. Frontiers in neuroendocrinology. vol 20. issue 4. 1999-11-30. PMID:10569279. |
the major neuroanatomical observations are the following: (1) pathways between the hypothalamus and autonomic centers are bidirectional: the ascending and descending fibers may use the same avenues; (2) the descending axons are mainly peptidergic (crf, vasopressin, oxytocin, somatostatin, enkephalin, pomc, and canp), while the ascending fibers are both peptidergic (enkephalin, npy, neurotensin, dynorphins) and catecholaminergic; (3) descending hypothalamic axons terminate directly on the sensory, preganglionic, and catecholaminergic neurons in the medulla and the spinal cord; (4) hypothalamic projections to the autonomic centers are always bilateral; (5) while medullary autonomic and catecholaminergic fibers innervate hypothalamic neurons directly, spinohypothalamic axons are relayed on neurons in the lateral hypothalamus. |
1999-11-30 |
2023-08-12 |
rat |
| A Javed, M C Kamradt, L D Van de Kar, T S Gra. D-Fenfluramine induces serotonin-mediated Fos expression in corticotropin-releasing factor and oxytocin neurons of the hypothalamus, and serotonin-independent Fos expression in enkephalin and neurotensin neurons of the amygdala. Neuroscience. vol 90. issue 3. 1999-06-14. PMID:10218785. |
d-fenfluramine induces serotonin-mediated fos expression in corticotropin-releasing factor and oxytocin neurons of the hypothalamus, and serotonin-independent fos expression in enkephalin and neurotensin neurons of the amygdala. |
1999-06-14 |
2023-08-12 |
rat |
| A Javed, M C Kamradt, L D Van de Kar, T S Gra. D-Fenfluramine induces serotonin-mediated Fos expression in corticotropin-releasing factor and oxytocin neurons of the hypothalamus, and serotonin-independent Fos expression in enkephalin and neurotensin neurons of the amygdala. Neuroscience. vol 90. issue 3. 1999-06-14. PMID:10218785. |
the approximate percentages of peptidergic neurons that contained fos immunoreactivity after d-fenfluramine administration were 94% of corticotropin-releasing factor and 22% of oxytocin cells in the paraventricular nucleus of the hypothalamus, 6% of oxytocin cells in the supraoptic nucleus of the hypothalamus, 36% of enkephalin and 15% of neurotensin cells in the central amygdaloid nucleus, and 19% of enkephalin and 9% of neurotensin cells in the bed nucleus of the stria terminalis. |
1999-06-14 |
2023-08-12 |
rat |
| A Tárno. Rare-event sorting by fixed-time flow cytometry based on changes in intracellular free calcium. Cytometry. vol 27. issue 1. 1997-03-26. PMID:9000586. |
non-transfected and transfected nih/3t3 mouse fibroblasts were stimulated with a cocktail of the neurotransmitters oxytocin, serotonin, substance p, noradrenalin, vasopressin, and neurotensin. |
1997-03-26 |
2023-08-12 |
mouse |
| J Billiar. Functional heterogeneity of pituitary gonadotropes in response to a variety of neuromodulators. Molecular and cellular endocrinology. vol 123. issue 2. 1997-03-12. PMID:8961253. |
endothelin-1, oxytocin, neurotensin, pituitary adenylate cyclase-activating polypeptide, and serotonin raised [ca2+]i and evoked lh release as assayed by the reverse hemolytic plaque assay. |
1997-03-12 |
2023-08-12 |
rat |
| R M O'Leary, S P Gallagher, B O'Conno. Purification and characterization of a novel membrane-bound form of prolyl endopeptidase from bovine brain. The international journal of biochemistry & cell biology. vol 28. issue 4. 1997-02-18. PMID:9026355. |
prolyl endopeptidase has been predominantly described as a cytosolic activity capable of cleaving a number of important neuropeptides (including trh, lhrh, bradykinin, angiotensin, substance p, neurotensin, oxytocin and vasopressin) on the carboxy side of proline. |
1997-02-18 |
2023-08-12 |
cattle |