All Relations between mog and oligodendrocyte

Publication Sentence Publish Date Extraction Date Species
Antonella Casamassa, Claudia La Rocca, Sophie Sokolow, Andre Herchuelz, Giuseppe Matarese, Lucio Annunziato, Francesca Bosci. Ncx3 gene ablation impairs oligodendrocyte precursor response and increases susceptibility to experimental autoimmune encephalomyelitis. Glia. vol 64. issue 7. 2018-01-02. PMID:27120265. here ncx3 involvement was studied in myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), an animal model of multiple sclerosis. 2018-01-02 2023-08-13 mouse
Min Su, Yujun Lin, Cheng Cui, Xiaohong Tian, Xiuling Lu, Zhixu He, Laijun La. ESC-derived thymic epithelial cells expressing MOG prevents EAE by central and peripheral tolerance mechanisms. Cellular immunology. vol 322. 2017-12-29. PMID:29074250. experimental autoimmune encephalomyelitis (eae) is an animal model for multiple sclerosis (ms), and is induced by immunization with disease-causative self-antigens such as myelin oligodendrocyte glycoprotein (mog). 2017-12-29 2023-08-13 mouse
Sun Mi Gu, Jaesuk Yun, Dong Ju Son, Hoi Yeong Kim, Kyung Tak Nam, Hae Deun Kim, Min Gi Choi, Jeong Soon Choi, Young Min Kim, Sang-Bae Han, Jin Tae Hon. Piperlongumine attenuates experimental autoimmune encephalomyelitis through inhibition of NF-kappaB activity. Free radical biology & medicine. vol 103. 2017-12-20. PMID:28011150. the mice were immunized with myelin oligodendrocyte glycoprotein 35-55 (mog 2017-12-20 2023-08-13 mouse
Miriam Fernández, Eva M Monsalve, Susana López-López, Almudena Ruiz-García, Susana Mellado, Elena Caminos, José Javier García-Ramírez, Jorge Laborda, Pedro Tranque, María José M Díaz-Guerr. Absence of Notch1 in murine myeloid cells attenuates the development of experimental autoimmune encephalomyelitis by affecting Th1 and Th17 priming. European journal of immunology. vol 47. issue 12. 2017-12-18. PMID:28762472. thus, the present study evaluates the role of the notch1 receptor in myeloid cells on the progression of myelin oligodendrocyte glycoprotein (mog) 2017-12-18 2023-08-13 mouse
Silke Kinzel, Klaus Lehmann-Horn, Sebastian Torke, Darius Häusler, Anne Winkler, Christine Stadelmann, Natalie Payne, Linda Feldmann, Albert Saiz, Markus Reindl, Patrice H Lalive, Claude C Bernard, Wolfgang Brück, Martin S Webe. Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen. Acta neuropathologica. vol 132. issue 1. 2017-12-04. PMID:27022743. in a transgenic mouse model, constitutive production of ab against myelin oligodendrocyte glycoprotein (mog) was sufficient to promote spontaneous experimental autoimmune encephalomyelitis (eae) in the absence of b cells, when mice endogenously contained mog-recognizing t cells. 2017-12-04 2023-08-13 mouse
Cedric Misslin, Maria Velasco-Estevez, Marie Albert, Sinead A O'Sullivan, Kumlesh K De. Phospholipase A2 is involved in galactosylsphingosine-induced astrocyte toxicity, neuronal damage and demyelination. PloS one. vol 12. issue 11. 2017-12-04. PMID:29095858. supporting a role for pla2 in psychosine-induced cell death of oligodendrocytes and astrocytes, the results show inhibition of pla2 attenuates psychosine-induced decrease in the expression of astrocyte marker vimentin as well as myelin basic protein (mbp), myelin oligodendrocyte glycoprotein (mog) and the neuronal marker smi-32 in organotypic slice cultures. 2017-12-04 2023-08-13 human
Bo Li, Xi Wang, In Young Choi, Yu-Chen Wang, Siyuan Liu, Alexander T Pham, Heesung Moon, Drake J Smith, Dinesh S Rao, Mark P Boldin, Lili Yan. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. The Journal of clinical investigation. vol 127. issue 10. 2017-10-19. PMID:28872459. we bred mir-146a-deficient mice with 2d2 t cell receptor-tg mice to generate 2d2 cd4 t cells that are deficient in mir-146a and specific for myelin oligodendrocyte glycoprotein (mog), an autoantigen in the eae model. 2017-10-19 2023-08-13 mouse
Ewa Kozela, Ana Juknat, Fuying Gao, Nathali Kaushansky, Giovanni Coppola, Zvi Voge. Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. Journal of neuroinflammation. vol 13. issue 1. 2017-09-29. PMID:27256343. our previous studies showed that the non-psychoactive cannabinoid, cannabidiol (cbd), ameliorates the clinical symptoms in mouse myelin oligodendrocyte glycoprotein (mog)35-55-induced experimental autoimmune encephalomyelitis model of multiple sclerosis (ms) as well as decreases the memory mog35-55-specific t cell (tmog) proliferation and cytokine secretion including il-17, a key autoimmune factor. 2017-09-29 2023-08-13 mouse
Elena Morandi, S Anwar Jagessar, Bert A 't Hart, Bruno Gra. EBV Infection Empowers Human B Cells for Autoimmunity: Role of Autophagy and Relevance to Multiple Sclerosis. Journal of immunology (Baltimore, Md. : 1950). vol 199. issue 2. 2017-09-29. PMID:28592428. we reported in a nonhuman primate experimental autoimmune encephalomyelitis model that an ebv-related lymphocryptovirus enables b cells to protect a proteolysis-sensitive immunodominant myelin oligodendrocyte glycoprotein (mog) epitope (residues 40-48) against destructive processing. 2017-09-29 2023-08-13 human
Fanny C F Ip, Yu Pong Ng, Terry C T Or, Peiran Sun, Guangmiao Fu, Jessica Y H Li, Wen-Cai Ye, Tom H Cheung, Nancy Y I. Anemoside A3 ameliorates experimental autoimmune encephalomyelitis by modulating T helper 17 cell response. PloS one. vol 12. issue 7. 2017-09-28. PMID:28759648. in vitro studies revealed that aa3 inhibited the t cell response toward the encephalitogenic epitope of myelin oligodendrocyte glycoprotein (mog). 2017-09-28 2023-08-13 mouse
Tanja Kuhlmann, Samuel Ludwin, Alexandre Prat, Jack Antel, Wolfgang Brück, Hans Lassman. An updated histological classification system for multiple sclerosis lesions. Acta neuropathologica. vol 133. issue 1. 2017-09-22. PMID:27988845. the former is defined by the presence in macrophages of major and small molecular weight myelin proteins, such as cyclic nucleotide diphosphoesterase (cnp), myelin oligodendrocyte glycoprotein (mog), or myelin-associated protein (mag), whereas macrophages in the latter demonstrate merely the presence of the major myelin proteins mbp or plp. 2017-09-22 2023-08-13 Not clear
Julia Barthelmes, Nadja Tafferner, Jennifer Kurz, Natasja de Bruin, Michael J Parnham, Gerd Geisslinger, Susanne Schiffman. Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues. Journal of visualized experiments : JoVE. issue 111. 2017-09-11. PMID:27214391. one of the eae models is induced with a peptide derived from the myelin oligodendrocyte protein (mog)35-55 in mice. 2017-09-11 2023-08-13 mouse
Sabine Herold, Prateek Kumar, Klaus Jung, Irina Graf, Henrike Menkhoff, Xenia Schulz, Mathias Bähr, Katharina Hei. CatWalk gait analysis in a rat model of multiple sclerosis. BMC neuroscience. vol 17. issue 1. 2017-08-21. PMID:27903258. myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) is a widely used animal model for multiple sclerosis. 2017-08-21 2023-08-13 rat
Amber C Chevalier, Thad A Rosenberge. Increasing acetyl-CoA metabolism attenuates injury and alters spinal cord lipid content in mice subjected to experimental autoimmune encephalomyelitis. Journal of neurochemistry. vol 141. issue 5. 2017-08-17. PMID:28369944. eae was induced by inoculating mice with a myelin oligodendrocyte glycoprotein peptide fragment (mog 2017-08-17 2023-08-13 mouse
Muammer Üçal, Michaela Tanja Haindl, Milena Z Adzemovic, Johannes Strasser, Lisa Theisl, Manuel Zeitelhofer, Klaus Kraitsy, Stefan Ropele, Ute Schäfer, Franz Fazekas, Sonja Hochmeiste. Widespread cortical demyelination of both hemispheres can be induced by injection of pro-inflammatory cytokines via an implanted catheter in the cortex of MOG-immunized rats. Experimental neurology. vol 294. 2017-08-17. PMID:28457906. after 14days the rats were immunized with 5μg myelin oligodendrocyte glycoprotein (mog) in incomplete freund's adjuvant, which did not cause any clinical signs but animals developed a stable anti-mog antibody titer. 2017-08-17 2023-08-13 rat
Duncheng Wang, Debjani Ghosh, S M Touhidul Islam, Cody D Moorman, Ashton E Thomason, Daniel S Wilkinson, Mark D Manni. IFN-β Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 197. issue 8. 2017-08-14. PMID:27619998. tolerance induction was specific for the tolerogenic vaccine ag plp178-191 or myelin oligodendrocyte glycoprotein (mog)35-55 in proteolipid protein- and mog-induced models of eae, respectively, and was abrogated by pretreatment with a depleting anti-cd25 mab. 2017-08-14 2023-08-13 mouse
Tetsuya Akaishi, Ichiro Nakashima, Takayuki Takeshita, Kimihiko Kaneko, Shunji Mugikura, Douglas Kazutoshi Sato, Toshiyuki Takahashi, Toru Nakazawa, Masashi Aoki, Kazuo Fujihar. Different etiologies and prognoses of optic neuritis in demyelinating diseases. Journal of neuroimmunology. vol 299. 2017-08-14. PMID:27725114. we compared the clinical features of optic neuritis (on) that are frequently observed in various central nervous system demyelinating diseases, including multiple sclerosis (ms), anti-aquaporin 4 (aqp4) antibody- and anti-myelin oligodendrocyte glycoprotein (mog) autoantibody-related diseases. 2017-08-14 2023-08-13 Not clear
Andreas Warnecke, Sravani Musunuri, Marie N'diaye, Tatyana Sandalova, Adnane Achour, Jonas Bergquist, Robert A Harri. Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype. Journal of neuroimmunology. vol 303. 2017-08-14. PMID:28011088. we here report that nitration of tyrosine 40 in myelin oligodendrocyte glycoprotein (mog) abrogates its encephalitogenicity both at protein and peptide levels in the experimental autoimmune encephalomyelitis (eae) model in h2 2017-08-14 2023-08-13 Not clear
Hadas Stiebel-Kalish, Itay Lotan, Judith Brody, Gabriel Chodick, Omer Bialer, Romain Marignier, Michael Bach, Mark Andrew Hellman. Retinal Nerve Fiber Layer May Be Better Preserved in MOG-IgG versus AQP4-IgG Optic Neuritis: A Cohort Study. PloS one. vol 12. issue 1. 2017-08-10. PMID:28125740. optic neuritis (on) in patients with anti-myelin oligodendrocyte glycoprotein (mog)-igg antibodies has been associated with a better clinical outcome than anti-aquaporin 4 (aqp4)- igg on. 2017-08-10 2023-08-13 Not clear
Ashutosh K Mangalam, Ramandeep Rattan, Hamid Suhail, Jaspreet Singh, Md Nasrul Hoda, Mandar Deshpande, Sadanand Fulzele, Alexander Denic, Viji Shridhar, Ashok Kumar, Benoit Viollet, Moses Rodriguez, Shailendra Gir. AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage-Th17 Axis. Journal of immunology (Baltimore, Md. : 1950). vol 197. issue 3. 2017-08-08. PMID:27354217. increased inflammatory response in α1ko mice was due to polarization of macrophages (mϕ) to proinflammatory m1 type phenotype (il-10(low)il-23/il-1β/il-6(high)), and these m1 mϕ showed stronger capacity to induce allogenic as well as ag-specific (myelin oligodendrocyte glycoprotein [mog]35-55) t cell response. 2017-08-08 2023-08-13 mouse