| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zuber Khan, Sidharth Mehan, Pankaj Kumar Maurya, Aakash Kumar, Ghanshyam Das Gupta, Acharan S Narula, Reni Kalfi. The Polygenic Nature of Multiple Sclerosis: Genetic Variants, Immunological Modulation, and Environmental Connections. Endocrine, metabolic & immune disorders drug targets. 2025-01-15. PMID:39810445. |
dysfunctions in genes regulating myelin integrity, such as mog (myelin oligodendrocyte glycoprotein), mag (myelin-associated glycoprotein), and plp1 (proteolipid protein 1), further drive ms pathogenesis. |
2025-01-15 |
2025-01-17 |
human |
| Ryan Ramdani, Julie Pique, Romain Deschamps, Jonathan Ciron, Elisabeth Maillart, Bertrand Audoin, Mikael Cohen, Hélène Zephir, David Laplaud, Xavier Ayrignac, Nicolas Collongues, Aurélie Ruet, Eric Thouvenot, Bertrand Bourre, Caroline Papeix, Lakhdar Benyahya, Romain Marignie. Evaluation of the predictive value of CSF-restricted oligoclonal bands on residual disability and risk of relapse in adult patients with MOGAD: MOGADOC study. Multiple sclerosis (Houndmills, Basingstoke, England). 2025-01-15. PMID:39812323. |
the clinical course of myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) is variable. |
2025-01-15 |
2025-01-17 |
Not clear |
| Rebeca T Stiepel, Sean R Simpson, Nicole Rose Lukesh, Denzel D Middleton, Dylan A Hendy, Luis Ontiveros-Padilla, Stephen A Ehrenzeller, Md Jahirul Islam, Erik S Pena, Michael A Carlock, Ted M Ross, Eric M Bachelder, Kristy M Ainsli. Induction of Antigen-Specific Tolerance in a Multiple Sclerosis Model without Broad Immunosuppression. ACS nano. 2025-01-15. PMID:39812522. |
after initial characterization and optimization, particles were tested in a myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis model of ms. |
2025-01-15 |
2025-01-17 |
mouse |
| R S Shaik, V H Ganaraja, A Bhattacharya, Manoj Kumar, L K Nitish, M Bhat, P K Pal, A Mahadevan, M Netravath. Preliminary observations in cortical excitability changes using transcranial magnetic stimulation (TMS), it's correlation with diffusion tensor imaging (DTI) in subjects with neuromyelitis optica spectrum disorder (NMOSD). Acta neurologica Belgica. 2025-01-12. PMID:39800771. |
neuromyelitis optica spectrum disorder (nmosd) is a relapsing central nervous system disease most commonly associated with aquaporin-4 antibodies (aqp4-ab) and myelin oligodendrocyte glycoprotein (mog) antibodies. |
2025-01-12 |
2025-01-16 |
human |
| Sara I Taha, Salwa I Bakr, Nermeen T Fouad, Dina Zamzam, Yasmine A Mohame. Clinical characteristics of anti-myelin oligodendrocyte glycoprotein antibody among aquaporin-4 negative neuromyelitis optica spectrum disorders in Egyptian patients. Scientific reports. vol 15. issue 1. 2025-01-09. PMID:39789036. |
among them, a subset has antibodies targeting myelin oligodendrocyte glycoprotein (mog), a condition now termed mog antibody-associated disease (mogad). |
2025-01-09 |
2025-01-13 |
Not clear |
| Tianjiao Duan, Song Ouyang, Zhaolan Hu, Qiuming Zeng, Weifan Yi. Clinical Analysis of MOG Antibody-Associated Disease Overlapped With Anti-NMDA Receptor Encephalitis: A Long-Term Retrospective Study. The European journal of neuroscience. vol 61. issue 1. 2025-01-09. PMID:39780343. |
to summarise the clinical characteristics, radiological features, treatments and prognosis of patients with myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad) overlapped with nmda receptor (nmdar) encephalitis. |
2025-01-09 |
2025-01-13 |
Not clear |
| Joseph S Miller, Michael Rose, Jonathan Roell, Samruddhi Ubhe, Tom Liu, Benjamin M Segal, Erica H Bel. A mini review of leveraging biobanking in the identification of novel biomarkers in neurological disorders: insights from a rapid single-cell sequencing pipeline. Frontiers in neuroscience. vol 18. 2025-01-08. PMID:39777270. |
moreover, assays designed to detect factors that are released by cns resident cells and diffuse into the csf and/or bloodstream (such as neurofilament light chain [nfl], glial fibrillar acidic protein [gfap] and amyloid beta peptides), and systemic factors that cross the blood-brain barrier to target cns-specific molecules (e.g., autoantibodies that bind either the nmda receptor [nmdar] or myelin oligodendrocyte glycoprotein [mog]), are increasingly deployed in clinical research and practice. |
2025-01-08 |
2025-01-13 |
Not clear |
| Ali Bigdeli, Mostafa Ghaderi-Zefrehei, Bluma J Lesch, Mehrdad Behmanesh, S Shahriar Ara. Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis. PloS one. vol 19. issue 12. 2025-01-08. PMID:39775333. |
an in-silico bioinformatics approach was undertaken in order to identify viral and bacterial antigens that resemble myelin oligodendrocyte glycoprotein (mog) and myelin basic protein (mbp). |
2025-01-08 |
2025-01-13 |
human |
| Brendan K Tao, Natalie Chen, Adrien Lusterio, Minj Shah, Chia-Chen Tsai, Sumana Naidu, Armin Handzic, Edward Margoli. Meta-regression of optic nerve imaging and visual outcome in myelin oligodendrocyte glycoprotein antibody optic neuritis. Journal of the neurological sciences. vol 468. 2024-12-31. PMID:39740576. |
few predictors of visual outcome after myelin oligodendrocyte glycoprotein (mog) auto-antibody disease optic neuritis (on) have been reliably elucidated. |
2024-12-31 |
2025-01-03 |
Not clear |
| Sarah Jesse, Marie Riemann, Hauke Schneider, Marius Ringelstein, Nico Melzer, Niklas Vogel, Lena Kristina Pfeffer, Manuel A Friese, Kurt-Wolfram Sühs, Dominica Hudasch, Philipp Schwenkenbecher, Albrecht Günther, Christian Geis, Jonathan Wickel, Martin Lesser, Annika Kather, Frank Leypoldt, Justina Dargvainiene, Robert Markewitz, Klaus-Peter Wandinger, Franziska S Thaler, Joseph Kuchling, Katharina Wurdack, Lidia Sabater, Carsten Finke, Jan Leweren. Frequency, characteristics, and immunological accompaniments of ataxia in anti-NMDAR antibody-associated encephalitis. Frontiers in immunology. vol 15. 2024-12-30. PMID:39735552. |
transient cerebellar ataxia is common in pediatric nmdar-e. immune-mediated cerebellar ataxia may be associated with myelin oligodendrocyte glycoprotein (mog), aquaporin-4 (aqp-4), kelch-like family member 11 (klhl11), and glutamate kainate receptor subunit 2 (gluk2) antibodies, all of which may co-occur in nmdar-e. |
2024-12-30 |
2025-01-01 |
Not clear |
| Tejas Shivarthi, Mahima Sriram, Muddana Nikhilesh, Pula Rohan, Sai Sudeep Reddy Jinna, Sudheeran Kannoth, Udit Saraf, Vivek Nambiar, Siby Gopinath, Gopikrishnan Unnikrishnan, Anandkumar Anandakuttan, Annamma Mathai, Meena Thevarkalam, Suprabha Panicker, Vaishakh Anand, K P Vinayan, Abish Sudhaka. MOG IgG antibody positivity from laboratory to clinical practice: A real world experience. Multiple sclerosis and related disorders. vol 93. 2024-12-30. PMID:39736174. |
myelin oligodendrocyte glycoprotein (mog) associated disease (mogad) is an antibody-mediated inflammatory demyelinating disorder of the cns with varied presentations like optic neuritis (on), transverse myelitis, and cortical encephalitis. |
2024-12-30 |
2025-01-02 |
Not clear |
| Jessica R Salas, K M Ryan, Alyssa O Trias, Bao Ying Chen, Miriam Guemes, Zoran Galic, Kenneth A Schultz, Peter M Clar. Blocking Deoxycytidine Kinase in Activated Lymphocytes Depletes Deoxycytidine Triphosphate Pools and Alters Cell Cycle Kinetics to Yield Less Disease in a Mouse Multiple Sclerosis Model. Immunology. 2024-12-22. PMID:39710854. |
in prior work, we showed that targeting dck with the small molecule inhibitor tre-515 limits clinical symptoms in two myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae) mouse models of ms and decreases the levels of activated cd4 t and b lymphocytes in vivo. |
2024-12-22 |
2024-12-25 |
mouse |
| Ana Beatriz Ayroza Galvão Ribeiro Gomes, Su-Hyun Kim, Roxanne Pretzsch, Laila Kulsvehagen, Sabine Schaedelin, Jasmine Lerner, Nora Sandrine Wetzel, Pascal Benkert, Aleksandra Maleska Maceski, Jae-Won Hyun, Anne-Catherine Lecourt, Patrick Lipps, Vinicius Andreoli Schoeps, Aline De Moura Brasil Matos, Natalia Trombini Mendes, Samira Luisa Apóstolos-Pereira, Matthias Mehling, Tobias Derfuss, Ludwig Kappos, Dagoberto Callegaro, Jens Kuhle, Ho Jin Kim, Anne-Katrin Pröbste. Neurofilament Light Chain as a Discriminator of Disease Activity Status in MOG Antibody-Associated Disease. Neurology(R) neuroimmunology & neuroinflammation. vol 12. issue 1. 2024-12-20. PMID:39705633. |
in patients with myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad), acute disease activity is generally identified through medical history, neurologic examination, and imaging. |
2024-12-20 |
2024-12-23 |
Not clear |
| Rekha Khandia, Pankaj Gurjar, Priyanka, Victoria Romashchenko, Sami A Al-Hussain, Magdi E A Zak. Recent advances in stem cell therapy: efficacy, ethics, safety concerns, and future directions focusing on neurodegenerative disorders - a review. International journal of surgery (London, England). vol 110. issue 10. 2024-12-20. PMID:39705668. |
stem cell terminal differentiation before implantation ensures the implantation of correct cells and molecular markers like carbonic anhydrase ii, cnpase (2',3'-cyclic nucleotide 3'-phosphohydrolase), myelin basic protein (mbp), and myelin oligodendrocyte glycoprotein (mog) elucidate the differentiation. |
2024-12-20 |
2024-12-23 |
Not clear |
| Mariella Martorelli, Matthias Dengler, Julian Laux, Tina Fischer, Agne Vaiceliunaite, Ulrike Hahn, Thilo Weinstein, Santiago Cruces, Christina Pokoj, Luciano de Oliveira da Cunha, Lara Wohlbold, Pierre Koch, Stefan Laufer, Michael Burnet, Florian Maie. A Defined Diet Combined with Sonicated Inoculum Provides a High Incidence, Moderate Severity Form of Experimental Autoimmune Encephalomyelitis (EAE). ACS pharmacology & translational science. vol 7. issue 12. 2024-12-19. PMID:39698286. |
myelin oligodendrocyte glycoprotein 35-55 (mog |
2024-12-19 |
2024-12-21 |
Not clear |
| Xintong Xu, Yuhang Wang, Mingming Sun, Yuyu Li, Biyue Chen, Xiyun Chen, Quangang Xu, Shihui Wei, Huanfen Zho. Efficacy and safety of tocilizumab treatment in refractory MOG-IgG related optic neuritis. Therapeutic advances in neurological disorders. vol 17. 2024-12-18. PMID:39691444. |
myelin oligodendrocyte glycoprotein (mog) igg related optic neuritis (on) which manifests as recurrent episodes and severe visual impairment remains a challenging issue in relapse prevention. |
2024-12-18 |
2024-12-21 |
human |
| Tosi Sai, Keisuke Imai, Takehiro Yamada, Masanori Cho, Atsushi Yamamoto, Testuya Iok. [A case of paroxysmal dysarthria and ataxia appeared late after treatment of myelin oligodendrocyte glycoprotein (MOG) antibody-related isolated rhombencephalitis]. Rinsho shinkeigaku = Clinical neurology. 2024-12-18. PMID:39694520. |
[a case of paroxysmal dysarthria and ataxia appeared late after treatment of myelin oligodendrocyte glycoprotein (mog) antibody-related isolated rhombencephalitis]. |
2024-12-18 |
2024-12-21 |
Not clear |
| Tosi Sai, Keisuke Imai, Takehiro Yamada, Masanori Cho, Atsushi Yamamoto, Testuya Iok. [A case of paroxysmal dysarthria and ataxia appeared late after treatment of myelin oligodendrocyte glycoprotein (MOG) antibody-related isolated rhombencephalitis]. Rinsho shinkeigaku = Clinical neurology. 2024-12-18. PMID:39694520. |
based on the positive for anti myelin oligodendrocyte glycoprotein (mog) antibody in the serum, she was ultimately diagnosed with mog related rhombencephalitis and discharged to her home on the 45th day. |
2024-12-18 |
2024-12-21 |
Not clear |
| Reza Taghipour-Mirakmahaleh, Françoise Morin, Yu Zhang, Louis Bourhoven, Louis-Charles Béland, Qun Zhou, Julie Jaworski, Anna Park, Juan Manuel Dominguez, Jacques Corbeil, Eoin P Flanagan, Romain Marignier, Catherine Larochelle, Steven Kerfoot, Luc Vallière. Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy. bioRxiv : the preprint server for biology. 2024-12-16. PMID:39677612. |
here we report the discovery of autoantibody-secreting extrafollicular plasmablasts in eae induced with specific myelin oligodendrocyte glycoprotein (mog) antigens. |
2024-12-16 |
2024-12-21 |
mouse |
| Ryotaro Ikeguchi, Natsuki Kanda, Masaki Kobayashi, Kenta Masui, Masayuki Nitta, Tatsuro Misu, Yoshihiro Muragaki, Takakazu Kawamata, Noriyuki Shibata, Kazuo Kitagawa, Yuko Shimiz. CNS B cell infiltration in tumefactive anti-myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple sclerosis journal - experimental, translational and clinical. vol 10. issue 4. 2024-12-09. PMID:39651331. |
few studies have examined b cells among patients with anti-myelin oligodendrocyte glycoprotein (mog) antibody-associated disease (mogad), including brain pathology. |
2024-12-09 |
2024-12-12 |
Not clear |