| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer L Whitwell, Jia Xu, Jay Mandrekar, Bradley F Boeve, David S Knopman, Joseph E Parisi, Matthew L Senjem, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Frontal asymmetry in behavioral variant frontotemporal dementia: clinicoimaging and pathogenetic correlates. Neurobiology of aging. vol 34. issue 2. 2013-04-29. PMID:22502999. |
genetic features differed across groups with symmetric frontal lobes associated with c9orf72 and tau mutations, while asymmetric frontal lobes were associated with progranulin mutations. |
2013-04-29 |
2023-08-12 |
human |
| Colin J Mahoney, Jon Beck, Jonathan D Rohrer, Tammaryn Lashley, Kin Mok, Tim Shakespeare, Tom Yeatman, Elizabeth K Warrington, Jonathan M Schott, Nick C Fox, Martin N Rossor, John Hardy, John Collinge, Tamas Revesz, Simon Mead, Jason D Warre. Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366791. |
the neuroimaging profile of the c9orf72 expansion was significantly more symmetrical than progranulin mutations with significantly less temporal lobe involvement than microtubule-associated protein tau mutations. |
2012-04-09 |
2023-08-12 |
Not clear |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
a total of 76 subjects, including 56 with a clinical diagnosis of behavioural variant frontotemporal dementia and a mutation in one of these genes (19 with c9orf72 mutations, 25 with tau mutations and 12 with progranulin mutations) and 20 sporadic subjects with behavioural variant frontotemporal dementia (including 50% with amyotrophic lateral sclerosis), with magnetic resonance imaging were included in this study. |
2012-04-09 |
2023-08-12 |
human |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
neuroimaging signatures of frontotemporal dementia genetics: c9orf72, tau, progranulin and sporadics. |
2012-04-09 |
2023-08-12 |
human |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
patterns of atrophy therefore differed across subjects with c9orf72, tau and progranulin mutations and sporadic frontotemporal dementia. |
2012-04-09 |
2023-08-12 |
human |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
we aimed to determine the regional pattern of brain atrophy associated with the c9orf72 gene mutation, and to determine which regions best differentiate c9orf72 from subjects with mutations in tau and progranulin, and from sporadic frontotemporal dementia. |
2012-04-09 |
2023-08-12 |
human |