| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ayato Yamasaki, Iroha Imanishi, Kaori Tanaka, Yasuyuki Ohkawa, Makoto Tsuda, Takahiro Masud. IRF8 and MAFB drive distinct transcriptional machineries in different resident macrophages of the central nervous system. Communications biology. vol 7. issue 1. 2024-07-23. PMID:39043941. |
here we show, by myeloid cell-specific deletion of transcription factors, irf8 and mafb, that both adult microglia and cams utilize irf8 to maintain their core gene signatures, although the genes altered by irf8 deletion are different in the two macrophage populations. |
2024-07-23 |
2024-07-26 |
Not clear |
| Ayato Yamasaki, Iroha Imanishi, Kaori Tanaka, Yasuyuki Ohkawa, Makoto Tsuda, Takahiro Masud. IRF8 and MAFB drive distinct transcriptional machineries in different resident macrophages of the central nervous system. Communications biology. vol 7. issue 1. 2024-07-23. PMID:39043941. |
by contrast, mafb deficiency robustly affected the gene expression profile of adult microglia, whereas cams are almost independent of mafb. |
2024-07-23 |
2024-07-26 |
Not clear |
| Patrick Miller-Rhodes, Harris A Gelbar. The Cell Culture Environment Regulates the Transcription Factor MafB in BV-2 Microglia. Matters. vol 2021. 2021-05-13. PMID:33969051. |
the cell culture environment regulates the transcription factor mafb in bv-2 microglia. |
2021-05-13 |
2023-08-13 |
Not clear |
| Patrick Miller-Rhodes, Harris A Gelbar. The Cell Culture Environment Regulates the Transcription Factor MafB in BV-2 Microglia. Matters. vol 2021. 2021-05-13. PMID:33969051. |
here, we show that basal mafb levels in the bv-2 microglial cell line depend on the availability of lipids in the cell culture environment. |
2021-05-13 |
2023-08-13 |
Not clear |
| Hidetoshi Tozaki-Saitoh, Junya Masuda, Ryu Kawada, Chinami Kojima, Sosuke Yoneda, Takahiro Masuda, Kazuhide Inoue, Makoto Tsud. Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development. Glia. vol 67. issue 4. 2019-06-11. PMID:30485546. |
pni caused a rapid and marked increase of mafb expression selectively in spinal microglia but not in neurons. |
2019-06-11 |
2023-08-13 |
mouse |
| Hidetoshi Tozaki-Saitoh, Junya Masuda, Ryu Kawada, Chinami Kojima, Sosuke Yoneda, Takahiro Masuda, Kazuhide Inoue, Makoto Tsud. Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development. Glia. vol 67. issue 4. 2019-06-11. PMID:30485546. |
we propose that mafb is a key mediator of the pni-induced phenotypic alteration of spinal microglia and neuropathic pain development. |
2019-06-11 |
2023-08-13 |
mouse |
| Hidetoshi Tozaki-Saitoh, Junya Masuda, Ryu Kawada, Chinami Kojima, Sosuke Yoneda, Takahiro Masuda, Kazuhide Inoue, Makoto Tsud. Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development. Glia. vol 67. issue 4. 2019-06-11. PMID:30485546. |
transcription factor mafb contributes to the activation of spinal microglia underlying neuropathic pain development. |
2019-06-11 |
2023-08-13 |
mouse |
| Hidetoshi Tozaki-Saitoh, Junya Masuda, Ryu Kawada, Chinami Kojima, Sosuke Yoneda, Takahiro Masuda, Kazuhide Inoue, Makoto Tsud. Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development. Glia. vol 67. issue 4. 2019-06-11. PMID:30485546. |
furthermore, we found that intrathecal transfer of mafb deficient microglia did not induce mechanical hypersensitivity and that conditional mafb knockout mice did not develop neuropathic pain after pni. |
2019-06-11 |
2023-08-13 |
mouse |
| Hidetoshi Tozaki-Saitoh, Junya Masuda, Ryu Kawada, Chinami Kojima, Sosuke Yoneda, Takahiro Masuda, Kazuhide Inoue, Makoto Tsud. Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development. Glia. vol 67. issue 4. 2019-06-11. PMID:30485546. |
herein, we demonstrate that mafb, a dominant transcriptional regulator of mature microglia, is involved in the pathology of a mouse model of neuropathic pain. |
2019-06-11 |
2023-08-13 |
mouse |
| Orit Matcovitch-Natan, Deborah R Winter, Amir Giladi, Stephanie Vargas Aguilar, Amit Spinrad, Sandrine Sarrazin, Hila Ben-Yehuda, Eyal David, Fabiola Zelada González, Pierre Perrin, Hadas Keren-Shaul, Meital Gury, David Lara-Astaiso, Christoph A Thaiss, Merav Cohen, Keren Bahar Halpern, Kuti Baruch, Aleksandra Deczkowska, Erika Lorenzo-Vivas, Shalev Itzkovitz, Eran Elinav, Michael H Sieweke, Michal Schwartz, Ido Ami. Microglia development follows a stepwise program to regulate brain homeostasis. Science (New York, N.Y.). vol 353. issue 6301. 2016-08-25. PMID:27338705. |
knockout of the gene encoding the adult microglia transcription factor mafb and environmental perturbations, such as those affecting the microbiome or prenatal immune activation, led to disruption of developmental genes and immune response pathways. |
2016-08-25 |
2023-08-13 |
Not clear |
| Ryusuke Koshida, Hisashi Oishi, Michito Hamada, Satoru Takahash. MafB antagonizes phenotypic alteration induced by GM-CSF in microglia. Biochemical and biophysical research communications. vol 463. issue 1-2. 2015-08-24. PMID:25998393. |
mafb, a bzip transcriptional factor, is highly expressed in monocyte-macrophage lineage cells including microglia, although its role in microglia is largely unknown. |
2015-08-24 |
2023-08-13 |
Not clear |
| Ryusuke Koshida, Hisashi Oishi, Michito Hamada, Satoru Takahash. MafB antagonizes phenotypic alteration induced by GM-CSF in microglia. Biochemical and biophysical research communications. vol 463. issue 1-2. 2015-08-24. PMID:25998393. |
altogether, our study reveals that mafb is a negative regulator of gm-csf signaling in microglia. |
2015-08-24 |
2023-08-13 |
Not clear |
| Ryusuke Koshida, Hisashi Oishi, Michito Hamada, Satoru Takahash. MafB antagonizes phenotypic alteration induced by GM-CSF in microglia. Biochemical and biophysical research communications. vol 463. issue 1-2. 2015-08-24. PMID:25998393. |
mafb antagonizes phenotypic alteration induced by gm-csf in microglia. |
2015-08-24 |
2023-08-13 |
Not clear |
| Ryusuke Koshida, Hisashi Oishi, Michito Hamada, Satoru Takahash. MafB antagonizes phenotypic alteration induced by GM-CSF in microglia. Biochemical and biophysical research communications. vol 463. issue 1-2. 2015-08-24. PMID:25998393. |
we investigated the crosstalk between gm-csf signaling and mafb by analyzing primary microglia. |
2015-08-24 |
2023-08-13 |
Not clear |