| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsumasa Tsujinaka, Takaaki Nakamura, Hiroshi Maegawa, Mineko Fujimiya, Yoshihiko Nishio, Motoi Kudo, Atsunori Kashiwag. Diet high in lipid hydroperoxide by vitamin E deficiency induces insulin resistance and impaired insulin secretion in normal rats. Diabetes research and clinical practice. vol 67. issue 2. 2005-06-07. PMID:15649568. |
to clarify the effect of dietary lipid hydroperoxide (lpo) on development of glucose intolerance, we fed sprague-dawley rats on a diet containing elevated lpo level for 10 weeks and measured both insulin sensitivity and insulin secretion. |
2005-06-07 |
2023-08-12 |
rat |
| Katsumasa Tsujinaka, Takaaki Nakamura, Hiroshi Maegawa, Mineko Fujimiya, Yoshihiko Nishio, Motoi Kudo, Atsunori Kashiwag. Diet high in lipid hydroperoxide by vitamin E deficiency induces insulin resistance and impaired insulin secretion in normal rats. Diabetes research and clinical practice. vol 67. issue 2. 2005-06-07. PMID:15649568. |
in conclusion, our studies reveal that diet high in lpo by vitamin e deficiency accelerates glucose intolerance through impairments of both sensitivity and secretion of insulin. |
2005-06-07 |
2023-08-12 |
rat |
| L K N Okine, A K Nyarko, N Osei-Kwabena, I V Oppong, F Barnes, M Ofosuhen. The antidiabetic activity of the herbal preparation ADD-199 in mice: a comparative study with two oral hypoglycaemic drugs. Journal of ethnopharmacology. vol 97. issue 1. 2005-05-26. PMID:15652271. |
plasma glucose, insulin and lipids as well as liver glycogen, lipids and lipid peroxidation were measured following treatment for 8 weeks. |
2005-05-26 |
2023-08-12 |
mouse |
| Kunga Mohan Ramkumar, Muniappan Latha, Subramaniam Venkateswaran, Leelavinothan Pari, Rajendran Ananthan, Vengatesh Narmatha Ba. Modulatory effect of Gymnema montanum leaf extract on brain antioxidant status and lipid peroxidation in diabetic rats. Journal of medicinal food. vol 7. issue 3. 2005-04-28. PMID:15383233. |
ethanolic extract of g. montanum leaves was administered orally (50, 100, and 200 mg/kg of body weight) for 3 weeks, and changes in blood glucose, plasma insulin, and lipid peroxidation markers such as thiobarbituric acid-reactive substances (tbars), hydroperoxides, and levels of antioxidants, namely, superoxide dismutase, catalase, glutathione peroxidase, reduced glutathione, and glutathione-s-transferase, were examined in the brain of alloxan-induced diabetic rats. |
2005-04-28 |
2023-08-12 |
rat |
| Orly Eshach Adiv, Hannah Mandel, Naim Shehadeh, Carlos Knopf, Zila Shen-Or, Raanan Shami. Influence of co-administration of oral insulin and docosahexaenoic acid in mice. The Journal of nutritional biochemistry. vol 15. issue 10. 2005-03-29. PMID:15542356. |
at 28 days, fasting blood levels of glucose, insulin, lipids, lipid peroxidation analysis, docosahexaenoic acid plasma levels, and docosahexaenoic acid content in red blood cells were determined. |
2005-03-29 |
2023-08-12 |
mouse |
| David A Sass, Parke Chang, Kapil B Chopr. Nonalcoholic fatty liver disease: a clinical review. Digestive diseases and sciences. vol 50. issue 1. 2005-03-08. PMID:15712657. |
pathophysiologically, insulin resistance is thought to be pivotal in the development of steatosis, after which a second oxidative stressor produces lipid peroxidation and nonalcoholic steatohepatitis (nash). |
2005-03-08 |
2023-08-12 |
Not clear |
| Dilek Gogas Yavuz, Meral Yüksel, Oguzhan Deyneli, Yesim Ozen, Hasan Aydin, Sema Akali. Association of serum paraoxonase activity with insulin sensitivity and oxidative stress in hyperthyroid and TSH-suppressed nodular goitre patients. Clinical endocrinology. vol 61. issue 4. 2005-03-01. PMID:15473886. |
the present study was designed to evaluate pon1 activity and its relationship with preatherosclerotic markers such as lipid peroxidation and insulin resistance in hyperthyroid patients before and after propylthiouracil (ptu) treatment and in subjects with iatrogenic subclinical hyperthyroidism. |
2005-03-01 |
2023-08-12 |
human |
| M Indran, P Rokiah, S P Chan, U R Kuppusam. Alteration of lipid peroxidation and antioxidant enzymes in young Malaysian IDDM patients. The Medical journal of Malaysia. vol 59. issue 2. 2005-01-27. PMID:15559165. |
the present study was designed to explore the relationship between lipid peroxidation and antioxidant enzymes in young malaysian insulin dependant diabetes mellitus (iddm) patients. |
2005-01-27 |
2023-08-12 |
human |
| M Latha, L Par. Effect of an aqueous extract of Scoparia dulcis on blood glucose, plasma insulin and some polyol pathway enzymes in experimental rat diabetes. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 37. issue 4. 2004-10-21. PMID:15064821. |
the diabetic control rats (n = 6) presented a significant increase in blood glucose, sorbitol dehydrogenase, glycosylated hemoglobin and lipid peroxidation markers such as thiobarbituric acid reactive substances (tbars) and hydroperoxides, and a significant decrease in plasma insulin and antioxidant enzymes such as glutathione peroxidase (gpx), glutathione-s-transferase (gst) and reduced glutathione (gsh) compared to normal rats (n = 6). |
2004-10-21 |
2023-08-12 |
rat |
| Ana I Duarte, Maria S Santos, Raquel Seiça, Catarina R Oliveir. Oxidative stress affects synaptosomal gamma-aminobutyric acid and glutamate transport in diabetic rats: the role of insulin. Diabetes. vol 53. issue 8. 2004-09-17. PMID:15277393. |
the ascorbate/fe(2+)-induced increase in thiobarbituric acid reactive substances (tbarss) was similar in wistar and gk rats and was not reverted by insulin (1 micromol/l), suggesting that other mechanisms, rather than a direct effect in membrane lipid peroxidation, may mediate insulin neuroprotection. |
2004-09-17 |
2023-08-12 |
rat |
| L Pari, M Lath. Effect of scoparia dulcis (Sweet Broomweed) plant extract on plasma antioxidants in streptozotocin-induced experimental diabetes in male albino Wistar rats. Die Pharmazie. vol 59. issue 7. 2004-09-03. PMID:15296095. |
a single dose of streptozotocin (45 mg/kg body weight) produced decrease in insulin, hyperglycemia, increased lipid peroxidation (thiobarbituric reactive substances and lipid hydroperoxides) and decreased antioxidant levels (vitamin c, vitamin e, reduced glutathione, ceruloplasmin). |
2004-09-03 |
2023-08-12 |
rat |
| L Pari, M Lath. Effect of scoparia dulcis (Sweet Broomweed) plant extract on plasma antioxidants in streptozotocin-induced experimental diabetes in male albino Wistar rats. Die Pharmazie. vol 59. issue 7. 2004-09-03. PMID:15296095. |
oral administration of an aqueous extract of scoparia dulcis plant (200 mg/kg body weight) for 6 weeks to diabetic rats significantly increased the plasma insulin and plasma antioxidants and significantly decreased lipid peroxidation. |
2004-09-03 |
2023-08-12 |
rat |
| Ulf Risérus, Bengt Vessby, Johan Arnlöv, Samar Bas. Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. The American journal of clinical nutrition. vol 80. issue 2. 2004-08-31. PMID:15277146. |
effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. |
2004-08-31 |
2023-08-12 |
Not clear |
| León Krawiec, Ramón A Pizarro, Paula Aphalo, Elena M V de Cavanagh, Mario A Pisarev, Guillermo J Juvenal, Lucía Policastro, Laura V Bocaner. Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism. European journal of biochemistry. vol 271. issue 13. 2004-08-23. PMID:15206926. |
monolayer primary cultures of thyroid cells produce, in the presence of insulin, a cytosolic inhibitor of thyroid peroxidase (tpo), lacto peroxidase (lpo), horseradish peroxidase (hrpo) and glutathione peroxidase (gpx). |
2004-08-23 |
2023-08-12 |
cattle |
| Ian R Wanless, Koji Shiot. The pathogenesis of nonalcoholic steatohepatitis and other fatty liver diseases: a four-step model including the role of lipid release and hepatic venular obstruction in the progression to cirrhosis. Seminars in liver disease. vol 24. issue 1. 2004-07-22. PMID:15085490. |
the first step is steatosis facilitated by insulin, and the second is necrosis induced by intracellular lipid toxicity or lipid peroxidation, or both, modified by alcohol, drugs, and ischemia. |
2004-07-22 |
2023-08-12 |
Not clear |
| b' J Patockov\\xc3\\xa1, M Krsiak, P Marhol, E T\\xc5\\xafmov\\xc3\\xa. Cerebrolysin inhibits lipid peroxidation induced by insulin hypoglycemia in the brain and heart of mice. Physiological research. vol 52. issue 4. 2004-07-13. PMID:12899658.' |
cerebrolysin inhibits lipid peroxidation induced by insulin hypoglycemia in the brain and heart of mice. |
2004-07-13 |
2023-08-12 |
mouse |
| b' J Patockov\\xc3\\xa1, M Krsiak, P Marhol, E T\\xc5\\xafmov\\xc3\\xa. Cerebrolysin inhibits lipid peroxidation induced by insulin hypoglycemia in the brain and heart of mice. Physiological research. vol 52. issue 4. 2004-07-13. PMID:12899658.' |
we have shown that subcomatous doses of insulin (6.0 iu/kg) significantly increase thiobarbituric acid reactive substances (tbars), especially malondialdehyde (mda) - the endproduct of lipid peroxidation, in the brain and heart of mice. |
2004-07-13 |
2023-08-12 |
mouse |
| b' J Patockov\\xc3\\xa1, M Krsiak, P Marhol, E T\\xc5\\xafmov\\xc3\\xa. Cerebrolysin inhibits lipid peroxidation induced by insulin hypoglycemia in the brain and heart of mice. Physiological research. vol 52. issue 4. 2004-07-13. PMID:12899658.' |
although cerebrolysin was not able to affect serum parameters after subcomatous insulin injection, the drug significantly influenced lipid peroxidation. |
2004-07-13 |
2023-08-12 |
mouse |
| Damien Demozay, Stéphane Rocchi, Jean-Christophe Mas, Sophie Grillo, Luciano Pirola, Carine Chavey, Emmanuel Van Obberghe. Fatty aldehyde dehydrogenase: potential role in oxidative stress protection and regulation of its gene expression by insulin. The Journal of biological chemistry. vol 279. issue 8. 2004-04-30. PMID:14638678. |
by employing rna arbitrarily primed-pcr to search for novel phosphatidylinositol 3-kinase-regulated genes in response to insulin in isolated rat adipocytes, we identified fatty aldehyde dehydrogenase (faldh), a key component of the detoxification pathway of aldehydes arising from lipid peroxidation events. |
2004-04-30 |
2023-08-12 |
mouse |
| S Srividhya, M K Ravichandran, C V Anuradh. Metformin attenuates blood lipid peroxidation and potentiates antioxidant defense in high fructose-fed rats. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB). vol 6. issue 6. 2004-04-29. PMID:14972791. |
we investigated the effect of an insulin sensitizer, metformin, on the plasma lipid peroxidation and antioxidant defense system in the erythrocytes of high fructose fed rats which form an animal model of insulin resistance. |
2004-04-29 |
2023-08-12 |
rat |