| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haohong Li, Yezheng Tao, Li Ma, Xing Liu, Lan M. β-Arrestin-2 inhibits preference for alcohol in mice and suppresses Akt signaling in the dorsal striatum. Neuroscience bulletin. vol 29. issue 5. 2014-05-02. PMID:23839051. |
furthermore, after the free consumption of alcohol, the activities of protein kinase b and glycogen synthase kinase 3β (gsk3β) increased in the dorsal striatum of wt mice, but not in ko mice, which showed high basal activity of akt in the dorsal striatum. |
2014-05-02 |
2023-08-12 |
mouse |
| Teresa Femenía, Jorge Manzanare. Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission. Addiction biology. vol 17. issue 2. 2012-05-08. PMID:21966993. |
these findings were associated with lower th and higher dat gene expression in the ventral tegmental area and substantia nigra, and with lower penk gene expression in the caudate-putamen (cpu), accumbens core (acbc) and accumbens shell (acbsh) in pdyn ko. |
2012-05-08 |
2023-08-12 |
mouse |
| Sandra Pérez-Rial, María S García-Gutiérrez, José A Molina, Beatriz G Pérez-Nievas, Catherine Ledent, Carlos Leiva, Juan C Leza, Jorge Manzanare. Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors. Neurobiology of aging. vol 32. issue 4. 2011-08-08. PMID:19419794. |
motor impairment, dopamine (da) neuronal activity and proenkephalin (penk) gene expression in the caudate-putamen (cpu) were measured in 6-ohda-lesioned and treated (l-dopa+benserazide) cb1 ko and wt mice. |
2011-08-08 |
2023-08-12 |
mouse |
| Azra Jaferi, Ping Zhou, Virginia M Picke. Enhanced dendritic availability of μ-opioid receptors in inhibitory neurons of the extended amygdala in mice deficient in the corticotropin-releasing factor-1 receptor. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506149. |
significantly, more cytoplasmic μ-or gold particles per dendritic area were observed selectively in gaba-containing dendrites of the bstal, but not of the dorsal striatum, in ko compared to wt mice. |
2011-02-04 |
2023-08-12 |
mouse |
| Ji-Hoon Yoo, Alexis Bailey, Micheal Ansonoff, John E Pintar, Audrey Matifas, Brigitte L Kieffer, Ian Kitche. Lack of genotype effect on D1, D2 receptors and dopamine transporter binding in triple MOP-, DOP-, and KOP-opioid receptor knockout mice of three different genetic backgrounds. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20196137. |
lower levels of d1 binding were observed in the caudate putamen of b6 x 129 ko mice compared with 129 ko mice. |
2010-09-08 |
2023-08-12 |
mouse |
| Oscar Diaz-Ruiz, Agustin Zapata, Lufei Shan, YaJun Zhang, Andreas C Tomac, Nasir Malik, Fidel de la Cruz, Cristina M Bäckma. Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons. PloS one. vol 4. issue 9. 2010-02-01. PMID:19750226. |
interestingly, quantitative microdialysis studies in pten ko mice revealed no alterations in basal da extracellular levels or evoked da release in the dorsal striatum, despite a significant increase in total da tissue levels. |
2010-02-01 |
2023-08-12 |
mouse |
| Régis Grailhe, Ana Cardona, Naïla Even, Isabelle Seif, Jean-Pierre Changeux, Isabelle Cloëz-Tayaran. Regional changes in the cholinergic system in mice lacking monoamine oxidase A. Brain research bulletin. vol 78. issue 6. 2009-03-13. PMID:19111597. |
a twofold increase in [(3)h]-hemicholinium-3 ([(3)h]-hc-3) binding to cht1 was observed in the caudate putamen, nucleus accumbens, and motor cortex in maoa ko mice as compared with wild-type (wt) mice. |
2009-03-13 |
2023-08-12 |
mouse |
| Daniel G Smith, Eleni T Tzavara, Janice Shaw, Susan Luecke, Mark Wade, Richard Davis, Craig Salhoff, George G Nomikos, Donald R Gehler. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673672. |
tissue contents of dopamine within the nac and caudate-putamen were not significantly different in ko compared with wt mice. |
2005-08-31 |
2023-08-12 |
mouse |
| Alex V Yarkov, Diane Hanger, Maria Reploge, Jeffrey N Joyc. Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice. Pharmacology, biochemistry, and behavior. vol 76. issue 3-4. 2004-08-24. PMID:14643855. |
mptp treatment produced equivalent 70% losses of dopamine fibers in the caudate putamen (cpu) and nucleus accumbens (nac) of wt and d(3) ko mice as compared to their control (vehicle injected) counterparts. |
2004-08-24 |
2023-08-12 |
mouse |
| E M Jagoda, D O Kiesewetter, K Shimoji, L Ravasi, M Yamada, J Gomeza, J Wess, W C Eckelma. Regional brain uptake of the muscarinic ligand, [18F]FP-TZTP, is greatly decreased in M2 receptor knockout mice but not in M1, M3 and M4 receptor knockout mice. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668051. |
using ex vivo autoradiography, the regional brain localization of [(18)f]fp-tztp in m2 knockout (m2 ko) was significantly decreased (51.3 to 61.4%; p<0.01) when compared to the wild-type (wt) mice in amygdala, brain stem, caudate putamen, cerebellum, cortex, hippocampus, hypothalamus, superior colliculus, and thalamus. |
2003-06-23 |
2023-08-12 |
mouse |