| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flavia Venetucci Gouveia, George M Ibrahi. Habenula as a Neural Substrate for Aggressive Behavior. Frontiers in psychiatry. vol 13. 2022-03-07. PMID:35250669. |
here we review the anatomical organization of the habenula and discuss several distinct mechanisms by which the hb is involved in the modulation of aggressive behaviors, and propose new investigations for the development of novel treatments targeting the habenula to reduce aggressive behaviors. |
2022-03-07 |
2023-08-13 |
Not clear |
| Gavin J B Elias, Jürgen Germann, Aaron Loh, Alexandre Boutet, Aditya Pancholi, Michelle E Beyn, Venkat Bhat, D Blake Woodside, Peter Giacobbe, Sidney H Kennedy, Andres M Lozan. Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression. Frontiers in psychiatry. vol 13. 2022-02-21. PMID:35185654. |
the habenula (hb) is a small, evolutionarily conserved epithalamic structure implicated in functions such as reward and mood regulation. |
2022-02-21 |
2023-08-13 |
Not clear |
| Chencheng Zhang, Yingying Zhang, Huichun Luo, Xinmeng Xu, Ti-Fei Yuan, Dianyou Li, Yi-Yun Cai, Hengfen Gong, Dai-Hui Peng, Yi-Ru Fang, Valerie Voon, Bomin Su. Bilateral Habenula deep brain stimulation for treatment-resistant depression: clinical findings and electrophysiological features. Translational psychiatry. vol 12. issue 1. 2022-02-04. PMID:35115488. |
recently, dbs of the habenula (hb) in the brain's anti-reward system has also been reported to alleviate depressive symptoms in patients with trd or bipolar disorder (bd). |
2022-02-04 |
2023-08-13 |
Not clear |
| Yachun Wang, Peng Qu, Yimeng Sun, Ziang Li, Lei Liu, Limin Yan. Association between increased inflammatory cytokine expression in the lateral habenular nucleus and depressive-like behavior induced by unpredictable chronic stress in rats. Experimental neurology. 2021-12-31. PMID:34971677. |
we found that ucs could increase ics in the cns, especially in the habenular nucleus (hb). |
2021-12-31 |
2023-08-13 |
rat |
| Nora L Salaberry, Jorge Mendoz. The circadian clock in the mouse habenula is set by catecholamines. Cell and tissue research. 2021-11-24. PMID:34816282. |
the epithalamic habenula (hb) contains a self-sustained circadian clock functionally coupled to the scn. |
2021-11-24 |
2023-08-13 |
mouse |
| Seo-Eun Cho, Chan-A Park, Kyoung-Sae Na, ChiHye Chung, Hyo-Jin Ma, Chang-Ki Kang, Seung-Gul Kan. Left-right asymmetric and smaller right habenula volume in major depressive disorder on high-resolution 7-T magnetic resonance imaging. PloS one. vol 16. issue 8. 2021-11-23. PMID:34343199. |
the habenula (hb) has been hypothesized to play an essential role in major depressive disorder (mdd) as it is considered to be an important node between fronto-limbic areas and midbrain monoaminergic structures based on animal studies. |
2021-11-23 |
2023-08-13 |
human |
| Seo-Eun Cho, Chan-A Park, Kyoung-Sae Na, ChiHye Chung, Hyo-Jin Ma, Chang-Ki Kang, Seung-Gul Kan. Left-right asymmetric and smaller right habenula volume in major depressive disorder on high-resolution 7-T magnetic resonance imaging. PloS one. vol 16. issue 8. 2021-11-23. PMID:34343199. |
two researchers blinded to the clinical data manually delineated the habenular nuclei and hb volume, and t1 values were calculated based on overlapping voxels. |
2021-11-23 |
2023-08-13 |
human |
| Jingjing Gao, Yuanyuan Li, Qiang Wei, Xuemei Li, Kai Wang, Yanghua Tian, Jiaojian Wan. Habenula and left angular gyrus circuit contributes to response of electroconvulsive therapy in major depressive disorder. Brain imaging and behavior. vol 15. issue 5. 2021-10-12. PMID:33244628. |
the habenula (hb), one of the hottest structures in depression, has been widely demonstrated to be involved in the neurobiology of depression. |
2021-10-12 |
2023-08-13 |
Not clear |
| Ana Maria Rivas-Grajales, Ramiro Salas, Meghan E Robinson, Karen Qi, James W Murrough, Sanjay J Mathe. Habenula Connectivity and Intravenous Ketamine in Treatment-Resistant Depression. The international journal of neuropsychopharmacology. vol 24. issue 5. 2021-10-06. PMID:33249434. |
a recently hypothesized antidepressant mechanism of action of ketamine is the inhibition of n-methyl-d-aspartate receptor-dependent bursting activity of the habenula (hb), a small brain structure that modulates reward and affective states. |
2021-10-06 |
2023-08-13 |
Not clear |
| Yuhan Wang, Chencheng Zhang, Yingying Zhang, Hengfen Gong, Jun Li, Haiyan Jin, Dianyou Li, Dengtang Liu, Bomin Su. Habenula deep brain stimulation for intractable schizophrenia: a pilot study. Neurosurgical focus. vol 49. issue 1. 2021-07-01. PMID:32610295. |
here, the authors explore the utility of dbs of the habenula (hb) in the clinical management of 2 young adult male patients with severe, chronic, and treatment-resistant schizophrenia. |
2021-07-01 |
2023-08-13 |
Not clear |
| Martin Metzger, Rudieri Souza, Leandro B Lima, Debora Bueno, Luciano Gonçalves, Chemutai Sego, Jose Donato, Sara J Shammah-Lagnad. Habenular connections with the dopaminergic and serotonergic system and their role in stress-related psychiatric disorders. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31833616. |
the habenula (hb) is a phylogenetically old epithalamic structure differentiated into two nuclear complexes, the medial (mhb) and lateral habenula (lhb). |
2021-06-28 |
2023-08-13 |
Not clear |
| Peng Qu, Yachun Wang, Lei Liu, Mengmeng Qi, Yimeng Sun, Siyang Zheng, Zichen Xu, Changhong Liu, Xiaoyan Bai, Qinggao Zhang, Limin Yan. Habenula lesions improve glucose metabolism in rats with type 2 diabetes by increasing insulin sensitivity and inhibiting gluconeogenesis. BMJ open diabetes research & care. vol 8. issue 1. 2021-06-21. PMID:32393480. |
the habenular nucleus (hb), a famous relay station in the midbrain, is vital for controlling many physiological functions of vertebrates. |
2021-06-21 |
2023-08-13 |
rat |
| Edra London, Jason C Wester, Michelle Bloyd, Shelby Bettencourt, Chris J McBain, Constantine A Strataki. Loss of habenular Prkar2a reduces hedonic eating and increases exercise motivation. JCI insight. vol 5. issue 23. 2021-05-24. PMID:33141766. |
the habenula (hb) is a bilateral, evolutionarily conserved epithalamic structure connecting forebrain and midbrain structures that has gained attention for its roles in depression, addiction, rewards processing, and motivation. |
2021-05-24 |
2023-08-13 |
mouse |
| Yu Tian, Zhonghao Wu, Yue Wang, Chong Chen, Yong He, Tianlan Lan, Yan Li, Mengge Bai, Heming Yu, Xiangyu Chen, Zhi Chen, Ke Cheng, Peng Xi. Alterations of neurotransmitters and related metabolites in the habenula from CUMS-susceptible and -resilient rats. Biochemical and biophysical research communications. vol 534. 2021-04-19. PMID:33246560. |
due to the in-depth discussion of the mechanism of new antidepressants like ketamine, the habenula (hb) was reported to be significant in the onset of mdd and the antidepressant mechanism. |
2021-04-19 |
2023-08-13 |
rat |
| Jürgen Germann, Flavia Venetucci Gouveia, Raquel C R Martinez, Marcus Vinicius Zanetti, Fábio Luís de Souza Duran, Tiffany M Chaim-Avancini, Mauricio H Serpa, M Mallar Chakravarty, Gabriel A Deveny. Fully Automated Habenula Segmentation Provides Robust and Reliable Volume Estimation Across Large Magnetic Resonance Imaging Datasets, Suggesting Intriguing Developmental Trajectories in Psychiatric Disease. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 5. issue 9. 2021-03-12. PMID:32222276. |
studies of habenula (hb) function and structure provided evidence of its involvement in psychiatric disorders, including schizophrenia and bipolar disorder. |
2021-03-12 |
2023-08-13 |
human |
| Wolfgang Grodd, Vinod Jangir Kumar, Almut Schüz, Tobias Lindig, Klaus Scheffle. The anterior and medial thalamic nuclei and the human limbic system: tracing the structural connectivity using diffusion-weighted imaging. Scientific reports. vol 10. issue 1. 2020-12-01. PMID:32616764. |
previous animal research indicates that the anterior nuclear group of the thalamus (ant), as well as the habenula (hb) and the adjacent mediodorsal nucleus (md) each play a vital role in the limbic circuitry. |
2020-12-01 |
2023-08-13 |
human |
| Lucia Caffino, Michel M M Verheij, Lin Que, Chao Guo, Judith R Homberg, Fabio Fumagall. Increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30144237. |
serotonin (5-ht) and the habenula (hb) contribute to motivational and emotional states such as depression and drug abuse. |
2020-10-28 |
2023-08-13 |
rat |
| Hiroyuki Ichijo, Tomoya Nakamura, Masahumi Kawaguchi, Yuichi Takeuch. An Evolutionary Hypothesis of Binary Opposition in Functional Incompatibility about Habenular Asymmetry in Vertebrates. Frontiers in neuroscience. vol 10. 2020-10-01. PMID:28101002. |
a typical example is found in the habenula (hb), which has long been known to be asymmetrical in many vertebrates, but has no remarkable relationship to lateralized behaviors. |
2020-10-01 |
2023-08-13 |
mouse |
| Matthew Schafer, Joo-Won Kim, Joshmi Joseph, Junqian Xu, Sophia Frangou, Gaelle E Douce. Imaging Habenula Volume in Schizophrenia and Bipolar Disorder. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30319463. |
the habenula (hb), a bilateral nucleus located next to the dorsomedial thalamus, is of particular relevance to psychiatric disorders based on preclinical evidence linking the hb to depressive and amotivational states. |
2020-09-30 |
2023-08-13 |
Not clear |
| Esther Yang, Jin Yong Kim, Soo Hyun Yang, Eunsoo Lee, Woong Sun, Hyun Woo Lee, Hyun Ki. Three-Dimensional Analysis of Mouse Habenula Subnuclei Reveals Reduced Volume and Gene Expression in the Lipopolysaccharide-mediated Depression Model. Experimental neurobiology. vol 28. issue 6. 2020-09-28. PMID:31902158. |
the habenula (hb) is small but important brain structure, anatomically and functionally links the forebrain with the midbrain to modulate various neuropsychiatric functions associated with drug addiction and emotion-associated dysfunctions. |
2020-09-28 |
2023-08-13 |
mouse |