Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R Gutiérrez Fuster, A León, G I Aparicio, F Brizuela Sotelo, C Scorticat. Combined additive effects of neuronal membrane glycoprotein GPM6a and the intercellular cell adhesion molecule ICAM5 on neuronal morphogenesis. Journal of neurochemistry. 2024-10-01. PMID:39352694. |
our study aimed to explore the functional relationship between gpm6a and icam5 in hippocampal culture neurons and cell lines. |
2024-10-01 |
2024-10-03 |
Not clear |
R Gutiérrez Fuster, A León, G I Aparicio, F Brizuela Sotelo, C Scorticat. Combined additive effects of neuronal membrane glycoprotein GPM6a and the intercellular cell adhesion molecule ICAM5 on neuronal morphogenesis. Journal of neurochemistry. 2024-10-01. PMID:39352694. |
these results were further corroborated by overexpressing gpm6a and icam5 in n2a cells and hippocampal neurons at 5 div. |
2024-10-01 |
2024-10-03 |
Not clear |
Sofia Elisa Alzuri, Nicolás Matías Rosas, Natasa Hlavacova, Daniela Jezova, Beata Fuchsov. Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats. Journal of neurochemistry. 2023-03-21. PMID:36943192. |
here, we employed the paradigm of chronic restraint stress in rats and using quantitative polymerase chain reaction (qpcr) showed downregulation of expression of gpm6a and the brain-derived neurotrophic factor (bdnf) genes at mrna level as well as mir-133b, mir-124-3p, but not mir-9-5p in the hippocampus of chronically stressed rats. |
2023-03-21 |
2023-08-14 |
rat |
Sofia Elisa Alzuri, Nicolás Matías Rosas, Natasa Hlavacova, Daniela Jezova, Beata Fuchsov. Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats. Journal of neurochemistry. 2023-03-21. PMID:36943192. |
role of mir-124-3p in regulatory mechanisms of gpm6a expression in the hippocampus of chronically stressed rats. |
2023-03-21 |
2023-08-14 |
rat |
Sofia Elisa Alzuri, Nicolás Matías Rosas, Natasa Hlavacova, Daniela Jezova, Beata Fuchsov. Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats. Journal of neurochemistry. 2023-03-21. PMID:36943192. |
decreased expression of gpm6a mrna is observed in the hippocampal tissue of suicide victims who suffered from depression and after chronic stress exposure in animals. |
2023-03-21 |
2023-08-14 |
rat |
Sofia Elisa Alzuri, Nicolás Matías Rosas, Natasa Hlavacova, Daniela Jezova, Beata Fuchsov. Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats. Journal of neurochemistry. 2023-03-21. PMID:36943192. |
upon mir-124 overexpression in hippocampal neurons cultured in vitro we observed enhanced neuronal arborization as evaluated by sholl analysis, increased gpm6a and mef2c expression, and decreased hdac5 expression. |
2023-03-21 |
2023-08-14 |
rat |
Nicolás M Rosas, Anabel Alvarez Juliá, Sofia E Alzuri, Alberto C Frasch, Beata Fuchsov. Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30233315. |
here, we demonstrate that the c- but not the n-terminal cytosolic end of gpm6a is required for the formation of filopodia by gpm6a in cultured neurons from rat hippocampus and in neuroblastoma cells n2a. |
2020-10-01 |
2023-08-13 |
rat |
Anabel Alvarez Juliá, Alberto C Frasch, Beata Fuchsov. Neuronal filopodium formation induced by the membrane glycoprotein M6a (Gpm6a) is facilitated by coronin-1a, Rac1, and p21-activated kinase 1 (Pak1). Journal of neurochemistry. vol 137. issue 1. 2016-08-15. PMID:26809475. |
by immunofluorescence microscopy, we demonstrated that in hippocampal neurons coro1a localizes in f-actin-enriched regions and some of coro1a spots co-localize with gpm6a labeling. |
2016-08-15 |
2023-08-13 |
rat |
Anabel Alvarez Juliá, Alberto C Frasch, Beata Fuchsov. Neuronal filopodium formation induced by the membrane glycoprotein M6a (Gpm6a) is facilitated by coronin-1a, Rac1, and p21-activated kinase 1 (Pak1). Journal of neurochemistry. vol 137. issue 1. 2016-08-15. PMID:26809475. |
here, we used co-immunoprecipitation assays with the anti-coro1a antibody to show that coro1a associates with gpm6a in rat hippocampal neurons. |
2016-08-15 |
2023-08-13 |
rat |
B Fuchsova, A Alvarez Juliá, H S Rizavi, A C Frasch, G N Pande. Altered expression of neuroplasticity-related genes in the brain of depressed suicides. Neuroscience. vol 299. 2016-02-29. PMID:25934039. |
expression of the neuronal membrane glycoprotein m6a (gpm6a), the proteolipid protein (plp/dm20) family member, is downregulated in the hippocampus of chronically stressed animals. |
2016-02-29 |
2023-08-13 |
human |
Marco P M Boks, Mechteld Hoogendoorn, Bart J Jungerius, Steven C Bakker, Iris E Sommer, Richard J Sinke, Roel A Ophoff, René S Kah. Do mood symptoms subdivide the schizophrenia phenotype? Association of the GMP6A gene with a depression subgroup. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18163405. |
gpm6a modulates the influence of stress on the hippocampus in animals. |
2008-12-04 |
2023-08-12 |
Not clear |