| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alex Reichenbach, Frederik J Steyn, Mark W Sleeman, Zane B Andrew. Ghrelin receptor expression and colocalization with anterior pituitary hormones using a GHSR-GFP mouse line. Endocrinology. vol 153. issue 11. 2013-01-17. PMID:22962259. |
however, the relative contribution of a direct action at the ghsr in the anterior pituitary gland vs. an indirect action at the ghsr in the hypothalamus remains undefined. |
2013-01-17 |
2023-08-12 |
mouse |
| Jin-yan Wang, Li-hua Wang, Liang-zhou Wei, Jun Wu, Ning Wei, Xin-juan Kong, Zi-bin Tia. [Association of gastric emptying with ghrelin, obestatin and receptor (GHSR, GPR-39) in hypothalamus of diabetic rats]. Zhonghua yi xue za zhi. vol 90. issue 16. 2010-09-09. PMID:20646435. |
[association of gastric emptying with ghrelin, obestatin and receptor (ghsr, gpr-39) in hypothalamus of diabetic rats]. |
2010-09-09 |
2023-08-12 |
rat |
| Jin-yan Wang, Li-hua Wang, Liang-zhou Wei, Jun Wu, Ning Wei, Xin-juan Kong, Zi-bin Tia. [Association of gastric emptying with ghrelin, obestatin and receptor (GHSR, GPR-39) in hypothalamus of diabetic rats]. Zhonghua yi xue za zhi. vol 90. issue 16. 2010-09-09. PMID:20646435. |
to investigate the association of gastric emptying with ghrelin, obestatin and ghsr, gpr-39 in hypothalamus of diabetic rats. |
2010-09-09 |
2023-08-12 |
rat |
| Ting Chen, Zhiguo Tang, Aifen Yan, Wensheng Li, Haoran Li. Molecular cloning and mRNA expression analysis of two GH secretagogue receptor transcripts in orange-spotted grouper (Epinephelus coioides). The Journal of endocrinology. vol 199. issue 2. 2009-07-10. PMID:18753333. |
finally, an in vitro study showed that expression of both gpghsr transcripts in pituitary and hypothalamus is downregulated by gh and ghrelin but not by des-acyl ghrelin, and this suggests that feedback regulation of ghsr also exists in teleostean fishes. |
2009-07-10 |
2023-08-12 |
Not clear |
| N M Malik, G B T Moore, R Kaur, Y-L Liu, S L Wood, R W Morrow, G J Sanger, P L R Andrew. Adaptive upregulation of gastric and hypothalamic ghrelin receptors and increased plasma ghrelin in a model of cancer chemotherapy-induced dyspepsia. Regulatory peptides. vol 148. issue 1-3. 2008-10-14. PMID:18455814. |
cisplatin increased ghsr mrna expression in the stomach (67%) and hypothalamus (52%) but not ghrl mrna expression and increased the percentage of acylated ghrl (7.03+/-1.35% vs. 11.38+/-2.40%) in the plasma. |
2008-10-14 |
2023-08-12 |
rat |
| N M Malik, G B T Moore, R Kaur, Y-L Liu, S L Wood, R W Morrow, G J Sanger, P L R Andrew. Adaptive upregulation of gastric and hypothalamic ghrelin receptors and increased plasma ghrelin in a model of cancer chemotherapy-induced dyspepsia. Regulatory peptides. vol 148. issue 1-3. 2008-10-14. PMID:18455814. |
treatment on the expression of ghrl and ghrelin receptor (ghsr) mrnas in the hypothalamus and the stomach at a time-point (2 days) when the effects of cisplatin are pronounced. |
2008-10-14 |
2023-08-12 |
rat |
| Angela M Vergnano, Francesco Ferrini, Chiara Salio, Laura Lossi, Mario Baratta, Adalberto Merigh. The gastrointestinal hormone ghrelin modulates inhibitory neurotransmission in deep laminae of mouse spinal cord dorsal horn. Endocrinology. vol 149. issue 5. 2008-06-10. PMID:18202139. |
however, central nervous system distribution of its receptor [type 1a gh secretagogue receptor (ghsr)] and modulation of neurotransmission in the hypothalamus suggest broader effects than originally predicted. |
2008-06-10 |
2023-08-12 |
mouse |
| Nicoletta Filigheddu, Viola F Gnocchi, Marco Coscia, Miriam Cappelli, Paolo E Porporato, Riccardo Taulli, Sara Traini, Gianluca Baldanzi, Federica Chianale, Santina Cutrupi, Elisa Arnoletti, Corrado Ghè, Alberto Fubini, Nicola Surico, Fabiola Sinigaglia, Carola Ponzetto, Giampiero Muccioli, Tiziana Crepaldi, Andrea Grazian. Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells. Molecular biology of the cell. vol 18. issue 3. 2007-04-24. PMID:17202410. |
ghrelin is an acylated peptidyl gastric hormone acting on the pituitary and hypothalamus to stimulate appetite, adiposity, and growth hormone release, through activation of growth hormone secretagogue receptor (ghsr)-1a receptor. |
2007-04-24 |
2023-08-12 |
Not clear |
| Gianluca Baldanzi, Nicoletta Filigheddu, Santina Cutrupi, Filomena Catapano, Sara Bonissoni, Alberto Fubini, Daniela Malan, Germano Baj, Riccarda Granata, Fabio Broglio, Mauro Papotti, Nicola Surico, Federico Bussolino, Jorgen Isgaard, Romano Deghenghi, Fabiola Sinigaglia, Maria Prat, Giampiero Muccioli, Ezio Ghigo, Andrea Grazian. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. The Journal of cell biology. vol 159. issue 6. 2003-02-21. PMID:12486113. |
ghrelin endocrine activities are entirely dependent on its acylation and are mediated by gh secretagogue (ghs) receptor (ghsr)-1a, a g protein-coupled receptor mostly expressed in the pituitary and hypothalamus, previously identified as the receptor for a group of synthetic molecules featuring gh secretagogue (ghs) activity. |
2003-02-21 |
2023-08-12 |
Not clear |
| R Horikawa, T Tachibana, N Katsumata, H Ishikawa, T Tanak. Regulation of pituitary growth hormone-secretagogue and growth hormone-releasing hormone receptor RNA expression in young Dwarf rats. Endocrine journal. vol 47 Suppl. 2000-10-25. PMID:10890184. |
growth hormone-secretagogue receptor (ghsr) rna is known to be expressed in the hypothalamus and pituitary. |
2000-10-25 |
2023-08-12 |
human |