| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Skamene, Y C Pate. Infusion of graded concentrations of somatostatin in man: pharmacokinetics and differential inhibitory effects on pituitary and islet hormones. Clinical endocrinology. vol 20. issue 5. 1984-09-14. PMID:6146413. |
the 25 micrograms/h infusion dose produced near-maximal suppression of gh secretion and inhibited insulin secretion but not tsh or glucagon secretion. |
1984-09-14 |
2023-08-12 |
human |
| A Skamene, Y C Pate. Infusion of graded concentrations of somatostatin in man: pharmacokinetics and differential inhibitory effects on pituitary and islet hormones. Clinical endocrinology. vol 20. issue 5. 1984-09-14. PMID:6146413. |
the intermediate dose significantly inhibited gh, tsh, and insulin but not glucagon whereas the 75 micrograms/h infusion suppressed all four hormones. |
1984-09-14 |
2023-08-12 |
human |
| D V Cohn, J J Elting, M Frick, R Eld. Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat. Endocrinology. vol 114. issue 6. 1984-07-13. PMID:6233131. |
in addition to their previously demonstrated presence in parathyroid and adrenal cells, the sp-i/ cga protein family was detected in cells of the thyroid that contained calcitonin and often srif but not thyroglobulin; in cells of the anterior pituitary staining for the alpha-subunit of tsh/fsh/lh but not in cells staining for gh, prl, acth, or beta-endorphin; in pancreatic islet cells staining for srif and pancreatic polypeptide-related peptides, but not for insulin or glucagon; in the celiac and mesenteric ganglia in cells some of which contained srif; and in the gastric antrum in cells containing srif, but not gastrin. |
1984-07-13 |
2023-08-12 |
rat |
| b' S R\\xc3\\xb6jdmark, K Lamminp\\xc3\\xa4\\xc3\\xa. Does acute endogenous hyperprolactinemia affect intravenous glucose tolerance in humans? Metabolism: clinical and experimental. vol 33. issue 6. 1984-07-09. PMID:6727656.' |
it is unlikely that this kg decline could have been caused by prolactin-induced changes in serum levels of insulin, cortisol, or growth hormone (gh), since these hormones showed glucose-elicited response patterns that were similar in the n-prl and h-prl states. |
1984-07-09 |
2023-08-12 |
human |
| P V Thadan. Effect of maternal ethanol ingestion on control of growth hormone secretion by biogenic amines in rat offspring. Neuroendocrinology. vol 38. issue 4. 1984-07-02. PMID:6374490. |
in controls, administration of cyproheptadine (a serotonin-blocking agent), or insulin, or exposure to cold, caused decreases in the levels of serum gh, whereas dopamine-induced inhibition in gh release was observed only in 10-day-old rats. |
1984-07-02 |
2023-08-12 |
rat |
| P V Thadan. Effect of maternal ethanol ingestion on control of growth hormone secretion by biogenic amines in rat offspring. Neuroendocrinology. vol 38. issue 4. 1984-07-02. PMID:6374490. |
in these ethanol-treated animals, insulin hypoglycemia, cold exposure, or dopamine-induced reductions in serum gh levels were not seen. |
1984-07-02 |
2023-08-12 |
rat |
| B R Carr, E R Simpso. Cholesterol synthesis by human fetal hepatocytes: effects of hormones. The Journal of clinical endocrinology and metabolism. vol 58. issue 6. 1984-07-02. PMID:6725509. |
in contrast, other hormones and factors, including insulin, glucagon, prl, gh, dehydroepiandrosterone and its sulfate, epidermal growth factor, fibroblast growth factor, t3, (bu)2camp, and cholera toxin, had no effect on the rate of cholesterol synthesis in human fetal liver cells. |
1984-07-02 |
2023-08-12 |
human |
| F Bottiglioni, D de Aloysio, G Nicoletti, M Mauloni, M Mantuano, R Mott. Physiopathological aspects of body overweight in the female climacteric. Maturitas. vol 5. issue 3. 1984-06-22. PMID:6427551. |
the correlation between overweight and the climacteric was studied in 550 menopause clinic patients by investigating certain clinical and sociocultural parameters (age, marital status, educational level, occupation and type of work, calorie intake, smoking habits, parity, blood pressure, previous hormonal therapy and climacteric symptoms), evaluating plasma levels of various hormones (17 beta-oestradiol, follicle-stimulating hormone (fsh), luteinizing (lh), testosterone, hydrocortisone, adrenocorticotrophic hormone (acth), triiodothyronine (t3), thyroxine (t4), growth hormone (gh) and insulin), glucose and various lipid fractions (total lipids, total cholesterol, nonesterified fatty acids (nefa), triglycerides and phospholipids) and exploring the blood-clotting pattern ( owren 's test, euglobulin lysis time, antithrombin iii and prothrombin agglutination time (pat). |
1984-06-22 |
2023-08-12 |
human |
| A A Ladita. Hormonal changes in severely malnourished children. African journal of medicine and medical sciences. vol 12. issue 3-4. 1984-06-11. PMID:6326545. |
serum insulin levels were depressed and growth hormone (gh) elevated among the kwashiorkor children most especially among the kwashiorkor sub-groups ii and iii cases who had the greatest deficit in body weight. |
1984-06-11 |
2023-08-12 |
human |
| A A Ladita. Hormonal changes in severely malnourished children. African journal of medicine and medical sciences. vol 12. issue 3-4. 1984-06-11. PMID:6326545. |
with improved dietary intake and some degree of anthropometric recovery, gh concentration fell steadily while insulin rose especially among the kwashiorkor cases. |
1984-06-11 |
2023-08-12 |
human |
| M Franceschi, F Parmigiani, P Zamproni, G Cairoli, N Cana. Richards-Rundle syndrome, cochleovestibular dysfunction and neurofibromatosis in a family. Journal of neurology. vol 231. issue 1. 1984-06-08. PMID:6425460. |
in a sibship of six members we found two sisters with rrs together with baldness, impaired gh and prl secretion after stimulation and different degrees of impaired insulin secretion. |
1984-06-08 |
2023-08-12 |
human |
| S Melme. Insulin suppresses growth hormone secretion by rat pituitary cells. The Journal of clinical investigation. vol 73. issue 5. 1984-06-05. PMID:6371058. |
the effects of insulin on basal and hydrocortisone-induced growth hormone (gh) secretion were studied in rat pituitary tumor cells (gh3). |
1984-06-05 |
2023-08-12 |
rat |
| S Melme. Insulin suppresses growth hormone secretion by rat pituitary cells. The Journal of clinical investigation. vol 73. issue 5. 1984-06-05. PMID:6371058. |
cells were grown in monolayer culture and exposed to exogenously added insulin for up to 8 d. basal gh secretion was inhibited by insulin (0.7 nm) after a 48-h lag period by approximately 50% (p less than 0.01, vs. untreated control cells). |
1984-06-05 |
2023-08-12 |
rat |
| S Melme. Insulin suppresses growth hormone secretion by rat pituitary cells. The Journal of clinical investigation. vol 73. issue 5. 1984-06-05. PMID:6371058. |
the suppression of gh secretion was reversible, as removal of added insulin resulted in return of gh secretion to normal levels after 24 h. maximal suppression of basal gh secretion was achieved by 0.7 nm insulin, and these effects were prevented by simultaneous exposure of the cells to guinea pig anti-insulin serum (1:2,000). |
1984-06-05 |
2023-08-12 |
rat |
| S Melme. Insulin suppresses growth hormone secretion by rat pituitary cells. The Journal of clinical investigation. vol 73. issue 5. 1984-06-05. PMID:6371058. |
insulin (7 nm) significantly suppressed the fivefold hydrocortisone-induced gh stimulation during 5 d of incubation with up to 1,000 nm of the steroid (p less than 0.001). |
1984-06-05 |
2023-08-12 |
rat |
| S Melme. Insulin suppresses growth hormone secretion by rat pituitary cells. The Journal of clinical investigation. vol 73. issue 5. 1984-06-05. PMID:6371058. |
the results show that insulin exerts a direct, specific inhibitory effect on basal and hydrocortisone-induced gh secretion by gh3 cells unrelated to glucose utilization by the cells. |
1984-06-05 |
2023-08-12 |
rat |
| F Cavagnini, C Maraschini, A Dubini, G Ramella, L Danesi, R Fossat. Inhibition by phospholipid liposomes of the prolactin and cortisol response to insulin hypoglycemia in man. Psychopharmacology. vol 82. issue 3. 1984-05-30. PMID:6425893. |
in eight normal subjects, we have studied the effects of pl administration (250 mg as iv bolus plus additional 250 mg infused iv over a 60-min period), compared to placebo, on the prolactin (prl), cortisol and growth hormone (gh) response to an insulin tolerance test (itt). |
1984-05-30 |
2023-08-12 |
human |
| C Y Bowers, F A Momany, G A Reynolds, A Hon. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology. vol 114. issue 5. 1984-05-30. PMID:6714155. |
his-dtrp-ala-trp-dphe-lysnh2, [his1,lys6] ghrp, is a new synthetic hexapeptide which specifically elicits a dosage-related release of gh in vitro and in vivo without a concomitant release of lh, fsh, tsh, or prl and, in limited in vivo studies, insulin or glucagon. |
1984-05-30 |
2023-08-12 |
rat |
| D R Clemmon. Multiple hormones stimulate the production of somatomedin by cultured human fibroblasts. The Journal of clinical endocrinology and metabolism. vol 58. issue 5. 1984-05-14. PMID:6368579. |
in contrast, transient exposure to other known stimuli of ir-sm production, such as human gh, t4, and insulin, resulted in no stimulation. |
1984-05-14 |
2023-08-12 |
human |
| M L Vance, J L Borges, D L Kaiser, W S Evans, R Furlanetto, J L Thominet, L A Frohman, A D Rogol, R M MacLeod, S Bloo. Human pancreatic tumor growth hormone-releasing factor: dose-response relationships in normal man. The Journal of clinical endocrinology and metabolism. vol 58. issue 5. 1984-05-14. PMID:6423660. |
mean +/- sem peak gh was 20.2 +/- 1.0 ng/ml after insulin and 20.9 +/- 3.2 after hpgrf-40 treatment. |
1984-05-14 |
2023-08-12 |
human |