| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D F Condorelli, P Dell'Albani, M Corsaro, V Barresi, A M Giuffrida Stell. AMPA-selective glutamate receptor subunits in astroglial cultures. Journal of neuroscience research. vol 36. issue 3. 1994-01-31. PMID:8271313. |
we analysed ampa ionotropic receptor subunits at the mrna level (glur-1 to -4) and at the protein level (glur-1 and glur-2/3/4c) in "primary astroglial cultures" (non-neuronal cell cultures highly enriched in glial fibrillary acidic protein [gfap] positive cells) prepared from newborn rat cerebral hemispheres, cerebral cortex, hippocampus, and striatum and in "brain non-neuronal cell cultures" (low percentage of gfap positive cells) prepared from cerebellum, brainstem, mesencephalon, and hypothalamus. |
1994-01-31 |
2023-08-12 |
rat |
| N R Nichols, J R Day, N J Laping, S A Johnson, C E Finc. GFAP mRNA increases with age in rat and human brain. Neurobiology of aging. vol 14. issue 5. 1994-01-04. PMID:8247224. |
gfap mrna increased in the hippocampus and striatum of 24 versus 6- to 7-month-old rats. |
1994-01-04 |
2023-08-12 |
mouse |
| N R Nichols, J R Day, N J Laping, S A Johnson, C E Finc. GFAP mRNA increases with age in rat and human brain. Neurobiology of aging. vol 14. issue 5. 1994-01-04. PMID:8247224. |
in human hippocampus, frontal and temporal cortex, gfap mrna also increased in older (60-79 years) compared with middle-aged (25-59 years) individuals. |
1994-01-04 |
2023-08-12 |
mouse |
| K Pilegaard, O Ladefoge. Toxic effects in rats of twelve weeks' dosing of 2-propanol, and neurotoxicity measured by densitometric measurements of glial fibrillary acidic protein in the dorsal hippocampus. In vivo (Athens, Greece). vol 7. issue 4. 1993-12-10. PMID:8218974. |
the content of glial fibrillary acidic protein (gfap) was measured semiquantitatively by a densitometric method applied to immunohistochemically stained sections from the dorsal hippocampus. |
1993-12-10 |
2023-08-12 |
rat |
| D J Bonthius, O Stewar. Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition by MK-801. Brain research. vol 618. issue 1. 1993-11-15. PMID:8402181. |
the kcl treatment led to a many-fold increase in gfap mrna content in the ipsilateral hippocampus and neocortex and, to a lesser extent, in the contralateral hippocampus, but did not affect gfap mrna levels in the contralateral cortex or in the thalamus. |
1993-11-15 |
2023-08-12 |
Not clear |
| D J Bonthius, O Stewar. Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition by MK-801. Brain research. vol 618. issue 1. 1993-11-15. PMID:8402181. |
the time course of increased expression of gfap mrna in the hippocampus differed markedly from that of the cortex. |
1993-11-15 |
2023-08-12 |
Not clear |
| D J Bonthius, O Stewar. Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition by MK-801. Brain research. vol 618. issue 1. 1993-11-15. PMID:8402181. |
in the hippocampus, gfap mrna levels rose rapidly to a maximum at 24 h post-exposure, then fell rapidly. |
1993-11-15 |
2023-08-12 |
Not clear |
| D J Bonthius, O Stewar. Induction of cortical spreading depression with potassium chloride upregulates levels of messenger RNA for glial fibrillary acidic protein in cortex and hippocampus: inhibition by MK-801. Brain research. vol 618. issue 1. 1993-11-15. PMID:8402181. |
intraperitoneal injection of mk-801, a non-competitive nmda antagonist which prevents spreading depression, blocked the upregulation of gfap mrna in both the hippocampus and the cortex, as demonstrated by both in situ and dot blot hybridization. |
1993-11-15 |
2023-08-12 |
Not clear |
| S Y Grooms, L Terracio, L S Jone. Anatomical localization of beta 1 integrin-like immunoreactivity in rat brain. Experimental neurology. vol 122. issue 2. 1993-10-26. PMID:7691647. |
this diffuse staining had a patterned appearance in certain structures, such as the apical dendritic field of ca1 in hippocampus, and occasional labeling of astrocytes, verified by labeling with gfap on adjacent sections, was noted. |
1993-10-26 |
2023-08-12 |
rat |
| J Kragh, T G Bolwig, D P Woldbye, O S Jørgense. Electroconvulsive shock and lidocaine-induced seizures in the rat activate astrocytes as measured by glial fibrillary acidic protein. Biological psychiatry. vol 33. issue 11-12. 1993-10-21. PMID:8373917. |
in adult rats given daily either ecs alone or in combination with lidocaine (experiment 1) we found that ecs significantly increased the concentration of the glial marker gfap in limbic areas: hippocampus, amygdala, and piriform cortex. |
1993-10-21 |
2023-08-12 |
rat |
| A P Wagner, G Reck, D Plat. Evidence that V+ fibronectin, GFAP and S100 beta mRNAs are increased in the hippocampus of aged rats. Experimental gerontology. vol 28. issue 2. 1993-08-12. PMID:8325350. |
evidence that v+ fibronectin, gfap and s100 beta mrnas are increased in the hippocampus of aged rats. |
1993-08-12 |
2023-08-12 |
rat |
| A P Wagner, G Reck, D Plat. Evidence that V+ fibronectin, GFAP and S100 beta mRNAs are increased in the hippocampus of aged rats. Experimental gerontology. vol 28. issue 2. 1993-08-12. PMID:8325350. |
in the present study, using rna gel-blot analysis, we characterized the developmental changes in the prevalence of mrna coding for fibronectin (fn), glial fibrillary acidic protein (gfap), neurotrophic protein s100 beta, and beta-actin mrna in rat hippocampus and forebrain from 1 to 720 days of age. |
1993-08-12 |
2023-08-12 |
rat |
| A P Wagner, G Reck, D Plat. Evidence that V+ fibronectin, GFAP and S100 beta mRNAs are increased in the hippocampus of aged rats. Experimental gerontology. vol 28. issue 2. 1993-08-12. PMID:8325350. |
as all these messages are localized primarily in astrocytes, we conclude that (a) astrocyte might play an active role in aging hippocampus and (b) an increase in s100 beta and gfap mrna expression may precede that for fn-v mrna expression in a hypothetical pathway of molecular events underlying neurodegeneration in the hippocampus of old rats. |
1993-08-12 |
2023-08-12 |
rat |
| M S Kelley, O Stewar. The role of neuronal activity in upregulating GFAP mRNA levels after electrolytic lesions of the entorhinal cortex. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 11. issue 2. 1993-08-12. PMID:8328294. |
this study evaluates whether the rapid transient increases in glial fibrillary acidic protein (gfap) mrna in the hippocampus after electrolytic lesions of the entorhinal cortex (ec) are triggered by lesion-induced changes in hippocampal neuronal activity (either the decreases that result from loss of afferent drive or transient increases that occur during lesion production). |
1993-08-12 |
2023-08-12 |
rat |
| M S Kelley, O Stewar. The role of neuronal activity in upregulating GFAP mRNA levels after electrolytic lesions of the entorhinal cortex. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 11. issue 2. 1993-08-12. PMID:8328294. |
to evaluate the role of activity, we carried out four experiments: (1) tetrodotoxin (ttx) was injected into the ec to mimic the decreases in afferent drive that occur after lesion; (2) ttx was injected into the ec or hippocampus before producing electrolytic lesions to block any abnormal activity induced during lesion production; (3) the ec was destroyed by aspiration, thus creating a lesion comparable in size to the electrolytic lesion, without passing direct current; (4) seizures were elicited by stimulating the ec of anesthetized rats, to examine whether electrographic seizures alone can induce the same type of increases in gfap mrna as lesions. |
1993-08-12 |
2023-08-12 |
rat |
| M S Kelley, O Stewar. The role of neuronal activity in upregulating GFAP mRNA levels after electrolytic lesions of the entorhinal cortex. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 11. issue 2. 1993-08-12. PMID:8328294. |
our results demonstrated that: (1) ttx injections into the ec did not induce the same increases in gfap mrna levels that occurred after ec lesions; (2) animals that received ttx injections into the ec prior to lesions exhibited increases in hippocampal gfap mrna that were nearly as great as following ec lesions alone; (3) aspiration lesions of the ec resulted in increases in gfap mrna that were comparable to those observed after electrolytic lesions; and (4) seizure-inducing stimulation of the ec resulted in 2-fold increases in gfap mrna in the hippocampus 24 hr after stimulation rather than the 5-13-fold increases observed after lesions. |
1993-08-12 |
2023-08-12 |
rat |
| M S Kelley, O Stewar. The role of neuronal activity in upregulating GFAP mRNA levels after electrolytic lesions of the entorhinal cortex. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 11. issue 2. 1993-08-12. PMID:8328294. |
these results suggest that lesion-induced changes in hippocampal neuronal activity are not solely responsible for inducing the rapid transient increases in gfap mrna levels in the hippocampus ipsilateral to ec lesions. |
1993-08-12 |
2023-08-12 |
rat |
| B Oderfeld-Nowak, W Jegliński, M Skup, J Skangiel-Kramska, M Zaremba, D Koczy. Differential effects of GM1 ganglioside treatment on glial fibrillary acidic protein content in the rat septum and hippocampus after partial interruption of their connections. Journal of neurochemistry. vol 61. issue 1. 1993-07-22. PMID:7685813. |
the glial fibrillary acidic protein (gfap) content was investigated using immunoblotting techniques in the septum and hippocampus of the rat after bilateral lateral fimbria transection. |
1993-07-22 |
2023-08-12 |
rat |
| B Oderfeld-Nowak, W Jegliński, M Skup, J Skangiel-Kramska, M Zaremba, D Koczy. Differential effects of GM1 ganglioside treatment on glial fibrillary acidic protein content in the rat septum and hippocampus after partial interruption of their connections. Journal of neurochemistry. vol 61. issue 1. 1993-07-22. PMID:7685813. |
seven days after surgery gfap content increased significantly both in the septum (140% of control) and hippocampus (120% in dorsal, the less denervated, and 145% in the most denervated ventral part), indicating the occurrence of reactive gliosis. |
1993-07-22 |
2023-08-12 |
rat |
| B Oderfeld-Nowak, W Jegliński, M Skup, J Skangiel-Kramska, M Zaremba, D Koczy. Differential effects of GM1 ganglioside treatment on glial fibrillary acidic protein content in the rat septum and hippocampus after partial interruption of their connections. Journal of neurochemistry. vol 61. issue 1. 1993-07-22. PMID:7685813. |
the gm1 treatment caused statistically significant attenuation of gfap increment in all hippocampal parts. |
1993-07-22 |
2023-08-12 |
rat |