| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Da-Bing Li, Jun Tang, Xiao-Tang Fan, Min Song, Hai-Wei Xu, Yun Ba. Comparative study of histopathology changes between the PS1/APP double transgenic mouse model and Abeta1-40 -injected rat model of Alzheimer disease. Neuroscience bulletin. vol 22. issue 1. 2012-10-02. PMID:17684540. |
results (1) the ps1/app transgenic mouse extensively displayed abeta deposits in the cortex and hippocampal structures, and gfap positive cells were aggregated in mass and surrounded the congo red-positive plaque. |
2012-10-02 |
2023-08-12 |
mouse |
| H Javed, M M Khan, A Ahmad, K Vaibhav, M E Ahmad, A Khan, M Ashafaq, F Islam, M S Siddiqui, M M Safhi, F Isla. Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience. vol 210. 2012-09-21. PMID:22441036. |
the results indicate that rutin attenuates stz-induced inflammation by reducing the expression of cyclooxygenase-2 (cox-2), glial fibrillary acidic protein (gfap), interleukin-8 (il-8), inducible nitric oxide synthase (inos), nuclear factor-kb, and preventing the morphological changes in hippocampus. |
2012-09-21 |
2023-08-12 |
rat |
| Peifang Jiang, Yi Sun, Tao Zhu, Canyang Zhan, Weizhong Gu, Tianming Yuan, Huimin Y. Endogenous neurogenesis in the hippocampus of developing rat after intrauterine infection. Brain research. vol 1459. 2012-09-18. PMID:22569202. |
to evaluate hippocampus neurogenesis, rats were sacrificed on p7 and p28, and their brains were prepared for evaluation of newly generated neural stem cells using double labeling of brdu and nestin, newly formed neurons using double labeling of brdu and neun, and newly formed astrocytes using double labeling of brdu and gfap. |
2012-09-18 |
2023-08-12 |
rat |
| R Adam Franssen, Amanda M Rzucidlo, Catherine L Franssen, J Ezekiel Hampton, Stanley A Benkovic, Massimo Bardi, Craig H Kinsley, Kelly G Lamber. Reproductive experience facilitates recovery from kainic acid-induced neural insult in female Long-Evans rats. Brain research. vol 1454. 2012-09-14. PMID:22483962. |
further, neurobiological assessments in experiment ii indicated that virgin ka exposed rats had significantly more glial fibrillary acidic protein (gfap)-immunoreactivity in the hippocampus, suggesting that they were in an earlier stage of neural recovery compared to maternal animals or, alternatively, may have exhibited more trauma than maternal animals. |
2012-09-14 |
2023-08-12 |
rat |
| Gabriel M Arisi, Megan Ruch, Maira L Foresti, Sanjib Mukherjee, Charles E Ribak, Lee A Shapir. Astrocyte Alterations in the Hippocampus Following Pilocarpine-induced Seizures in Aged Rats. Aging and disease. vol 2. issue 4. 2012-08-23. PMID:22396881. |
in the present study, the density and morphology of astrocytes expressing gfap were investigated in the hippocampus of aged rats that experienced status epilepticus induced by pilocarpine. |
2012-08-23 |
2023-08-12 |
rat |
| Karim Le Meur, Juan Mendizabal-Zubiaga, Pedro Grandes, Etienne Audina. GABA release by hippocampal astrocytes. Frontiers in computational neuroscience. vol 6. 2012-08-23. PMID:22912614. |
yet, electron microscopy examination of immunostained hippocampal sections shows that about 80% of hippocampal astrocytes [positive for glial fibrillary acidic protein (gfap)] were immunostained for gaba. |
2012-08-23 |
2023-08-12 |
rat |
| Rong-Fang Feng, Wen-Bin Li, Hui-Qing Liu, Qing-Jun Li, Xiao-Ling Chen, Ai-Min Zhou, Hong-Gang Zhao, Jie A. [Effects of alpha-methyl-(4-tetrazolyl-phenyl) glycine on the induction of hippocampal ischemic tolerance in the rat]. Sheng li xue bao : [Acta physiologica Sinica]. vol 55. issue 3. 2012-08-20. PMID:12817298. |
to explore the role of metabotropic glutamate receptor 2/3 mglur 2/3 in the induction of brain ischemic tolerance (bit), the influences of mglur2/3 antagonist alpha-methyl-(4-tetrazolyl-phenyl) glycine (mtpg) on the induction of bit and expression of glial fibrillary acidic protein (gfap) in the hippocampus were observed using thionin staining and gfap immunohistochemical staining in a rat brain ischemic model with four-vessel occlusion (4vo). |
2012-08-20 |
2023-08-12 |
rat |
| Felipe S Estrada, Vito S Hernández, Estela López-Hernández, Aleph A Corona-Morales, Hugo Solís, Alfonso Escobar, Limei Zhan. Glial activation in a pilocarpine rat model for epileptogenesis: a morphometric and quantitative analysis. Neuroscience letters. vol 514. issue 1. 2012-08-20. PMID:22395088. |
we assessed, quantitatively and morphometrically, glial fibrillary acidic protein (gfap) expression and cell densities in hippocampus in a dose-response manner 2, 4 and 8 weeks after the pilocarpine insult. |
2012-08-20 |
2023-08-12 |
rat |
| Felipe S Estrada, Vito S Hernández, Estela López-Hernández, Aleph A Corona-Morales, Hugo Solís, Alfonso Escobar, Limei Zhan. Glial activation in a pilocarpine rat model for epileptogenesis: a morphometric and quantitative analysis. Neuroscience letters. vol 514. issue 1. 2012-08-20. PMID:22395088. |
gfap expression evaluated at 2 weeks revealed dose-dependent cytoskeletal hypertrophy and loss of gfap+ cell densities in hippocampus. |
2012-08-20 |
2023-08-12 |
rat |
| Ana F B Ferreira, Caroline C Real, Alice C Rodrigues, Adilson S Alves, Luiz R G Britt. Short-term, moderate exercise is capable of inducing structural, BDNF-independent hippocampal plasticity. Brain research. vol 1425. 2012-08-13. PMID:22035567. |
in this study we used a short-term, moderate intensity treadmill exercise protocol to investigate the effects of exercise on usual markers of hippocampal synaptic and structural plasticity, such as synapsin i (syn), synaptophysin (syp), neurofilaments (nf), microtubule-associated protein 2 (map2), glutamate receptor subunits glur1 and glur2/3, brain-derived neurotrophic factor (bdnf) and glial fibrillary acidic protein (gfap). |
2012-08-13 |
2023-08-12 |
rat |
| Clara J Yuan, Jovy Marie D Quiocho, Airee Kim, Sunmee Wee, Chitra D Mandya. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacology, biochemistry, and behavior. vol 100. issue 1. 2012-07-23. PMID:21855565. |
further systematic analysis of ki-67 cells with gfap, sox2, and dcx revealed that lga methamphetamine-induced inhibition of hippocampal neurogenesis was attributable to impairment in the development of neuronal progenitors from preneuronal progenitors to immature neurons. |
2012-07-23 |
2023-08-12 |
rat |
| M López-Gallardo, A B López-Rodríguez, Á Llorente-Berzal, D Rotllant, K Mackie, A Armario, R Nadal, M-P Vivero. Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion. Neuroscience. vol 204. 2012-07-23. PMID:22001306. |
here we show the results obtained from investigating the immunohistochemical analysis of cb1 cannabinoid receptors, glial fibrillary acidic protein (gfap) positive (+) cells and brain-derived neurotrophic factor (bdnf) expression in the hippocampus of the same animals. |
2012-07-23 |
2023-08-12 |
rat |
| Luana Heimfarth, Samanta Oliveira Loureiro, Karina Pires Reis, Bárbara Ortiz de Lima, Fernanda Zamboni, Sabrina Lacerda, Angela Kronbauer Soska, Luisa Wild, João Batista Teixeira da Rocha, Regina Pessoa-Pureu. Diphenyl ditelluride induces hypophosphorylation of intermediate filaments through modulation of DARPP-32-dependent pathways in cerebral cortex of young rats. Archives of toxicology. vol 86. issue 2. 2012-07-16. PMID:21863293. |
we studied the effect of different concentrations of diphenyl ditelluride (phte)(2) on the in vitro phosphorylation of glial fibrillary acidic protein (gfap) and neurofilament (nf) subunits from cerebral cortex and hippocampus of rats during development. |
2012-07-16 |
2023-08-12 |
rat |
| Luana Heimfarth, Samanta Oliveira Loureiro, Karina Pires Reis, Bárbara Ortiz de Lima, Fernanda Zamboni, Sabrina Lacerda, Angela Kronbauer Soska, Luisa Wild, João Batista Teixeira da Rocha, Regina Pessoa-Pureu. Diphenyl ditelluride induces hypophosphorylation of intermediate filaments through modulation of DARPP-32-dependent pathways in cerebral cortex of young rats. Archives of toxicology. vol 86. issue 2. 2012-07-16. PMID:21863293. |
(phte)(2)-induced hypophosphorylation of gfap and nf subunits only in cerebral cortex of 9- and 15-day-old animals but not in hippocampus. |
2012-07-16 |
2023-08-12 |
rat |
| Z-F Zuo, W Wang, L Niu, Z-Z Kou, C Zhu, W Wang, X-H Zhao, D-S Luo, T Zhang, F-X Zhang, X-Z Liu, S-X Wu, Y-Q L. RU486 (mifepristone) ameliorates cognitive dysfunction and reverses the down-regulation of astrocytic N-myc downstream-regulated gene 2 in streptozotocin-induced type-1 diabetic rats. Neuroscience. vol 190. 2012-07-05. PMID:21712075. |
diabetic rats also presented down-regulation of glial fibrillary acidic protein (gfap, a key indicator of astrocytic reactivity) and ndrg2 in hippocampus revealed by immunohistochemistry staining, real-time pcr and western blot. |
2012-07-05 |
2023-08-12 |
rat |
| Z-F Zuo, W Wang, L Niu, Z-Z Kou, C Zhu, W Wang, X-H Zhao, D-S Luo, T Zhang, F-X Zhang, X-Z Liu, S-X Wu, Y-Q L. RU486 (mifepristone) ameliorates cognitive dysfunction and reverses the down-regulation of astrocytic N-myc downstream-regulated gene 2 in streptozotocin-induced type-1 diabetic rats. Neuroscience. vol 190. 2012-07-05. PMID:21712075. |
moreover, the diabetic cognitive impairments were ameliorated by 9-day glucocorticoids receptor (gr) blockade with ru486, and the down-regulation of hippocampal ndrg2 and gfap in diabetic animals was also attenuated by 9-day gr blockade. |
2012-07-05 |
2023-08-12 |
rat |
| Sarah J E Wong-Goodrich, Christina M Tognoni, Tiffany J Mellott, Melissa J Glenn, Jan K Blusztajn, Christina L William. Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood. Brain research. vol 1413. 2012-06-12. PMID:21840511. |
perhaps somewhat surprisingly, def rats were not more susceptible to seizure induction and showed similar levels of seizure-induced hippocampal histopathology, gad expression loss, upregulated hippocampal gfap and growth factor expression, and increased dentate cell and neuronal proliferation as that seen in con rats. |
2012-06-12 |
2023-08-12 |
rat |
| Fernanda Cechetti, Aline S Pagnussat, Paulo V Worm, Viviane Rostirolla Elsner, Juliana Ben, Marcelo Siveira da Costa, Régis Mestriner, Simone Nardin Weis, Carlos Alexandre Nett. Chronic brain hypoperfusion causes early glial activation and neuronal death, and subsequent long-term memory impairment. Brain research bulletin. vol 87. issue 1. 2012-05-17. PMID:22040859. |
in present study, the effects of permanent occlusion of common carotid arteries (2vo), a well established experimental model of brain ischemia, on memory function were investigated, as assessed by reference and working spatial memory protocols and the object recognition task; cell damage to the hippocampus, as measured through changes in immunoreactivity for gfap and the neuronal marker neun was also studied. |
2012-05-17 |
2023-08-12 |
rat |
| Dhiraj Maskey, Hye-Jin Kim, Hyung Gun Kim, Myeung Ju Ki. Calcium-binding proteins and GFAP immunoreactivity alterations in murine hippocampus after 1 month of exposure to 835 MHz radiofrequency at SAR values of 1.6 and 4.0 W/kg. Neuroscience letters. vol 506. issue 2. 2012-04-19. PMID:22133805. |
calcium-binding proteins and gfap immunoreactivity alterations in murine hippocampus after 1 month of exposure to 835 mhz radiofrequency at sar values of 1.6 and 4.0 w/kg. |
2012-04-19 |
2023-08-12 |
Not clear |
| Dhiraj Maskey, Hye-Jin Kim, Hyung Gun Kim, Myeung Ju Ki. Calcium-binding proteins and GFAP immunoreactivity alterations in murine hippocampus after 1 month of exposure to 835 MHz radiofrequency at SAR values of 1.6 and 4.0 W/kg. Neuroscience letters. vol 506. issue 2. 2012-04-19. PMID:22133805. |
different sar values [1.6 (e1.6 group) and 4.0 (e4 group) w/kg] were applied to determine the distribution of calbindin d28-k (cb), calretinin (cr), and glial fibrillary acidic protein (gfap) ir in murine hippocampus. |
2012-04-19 |
2023-08-12 |
Not clear |