| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Donna M Platt, Annemarie Duggan, Roger D Spealman, James M Cook, Xiaoyan Li, Wenyuan Yin, James K Rowlet. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15650112. |
the present study assessed the contribution of alpha(1)gaba(a) and alpha(5)gaba(a) receptors to the ds effects of ethanol. |
2005-07-05 |
2023-08-12 |
monkey |
| Donna M Platt, Annemarie Duggan, Roger D Spealman, James M Cook, Xiaoyan Li, Wenyuan Yin, James K Rowlet. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15650112. |
in substitution experiments, the alpha(1)gaba(a) agonists zolpidem, zaleplon, and cl 218,872 (3-methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine), the alpha(5)gaba(a) agonists qh-ii-066 (1-methyl-7-acetyleno-5-phenyl-1,3-dihydro-benzo[e]-1,4-diazepin-2-one) and panadiplon [3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-(1-methylethyl)imidazo(1,5-a)quinoxalin-4(5h)-one], and representative nonselective agonists partially to fully reproduced the ethanol ds. |
2005-07-05 |
2023-08-12 |
monkey |
| Donna M Platt, Annemarie Duggan, Roger D Spealman, James M Cook, Xiaoyan Li, Wenyuan Yin, James K Rowlet. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15650112. |
in antagonism studies, the alpha(1)gaba(a) antagonist beta-carboline-t-butyl ester did not attenuate the ds effects of ethanol or the ethanol-like effects of zolpidem and zaleplon. |
2005-07-05 |
2023-08-12 |
monkey |
| Donna M Platt, Annemarie Duggan, Roger D Spealman, James M Cook, Xiaoyan Li, Wenyuan Yin, James K Rowlet. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15650112. |
in contrast, pretreatment with the alpha(5)gaba(a) inverse agonist l-655,708 (ethyl[s]-11,12,13,13a-tetrahydro-7-methoxy-9-oxo-9h-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxlate) dose-dependently attenuated the ds effects of ethanol and the ethanol-like effects of qh-ii-066. |
2005-07-05 |
2023-08-12 |
monkey |
| Donna M Platt, Annemarie Duggan, Roger D Spealman, James M Cook, Xiaoyan Li, Wenyuan Yin, James K Rowlet. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 313. issue 2. 2005-07-05. PMID:15650112. |
these findings suggest a key role for alpha(5)gaba(a), but not alpha(1)gaba(a), receptor mechanisms in the ds effects of ethanol and the ethanol-like ds effects of benzodiazepine agonists. |
2005-07-05 |
2023-08-12 |
monkey |
| A Smith, C J Watson, K J Frantz, B Eppler, R T Kennedy, J Peri. Differential increase in taurine levels by low-dose ethanol in the dorsal and ventral striatum revealed by microdialysis with on-line capillary electrophoresis. Alcoholism, clinical and experimental research. vol 28. issue 7. 2005-01-19. PMID:15252289. |
we used a sensitive on-line assay of microdialysate content to test whether lower doses of ethanol selectively increase taurine efflux in vs as opposed to other dopaminergic regions not involved in reinforcement (e.g., dorsal striatum; ds). |
2005-01-19 |
2023-08-12 |
rat |
| A Smith, C J Watson, K J Frantz, B Eppler, R T Kennedy, J Peri. Differential increase in taurine levels by low-dose ethanol in the dorsal and ventral striatum revealed by microdialysis with on-line capillary electrophoresis. Alcoholism, clinical and experimental research. vol 28. issue 7. 2005-01-19. PMID:15252289. |
adult male rats with microdialysis probes in vs or ds were injected with ethanol (0, 0.5, 1, and 2 g/kg intraperitoneally), and the amino acid content of the dialysate was measured every 11 sec using capillary electrophoresis and laser-induced fluorescence detection. |
2005-01-19 |
2023-08-12 |
rat |
| Anna H Kaksonen, Peter D Franzmann, Jaakko A Puhakk. Effects of hydraulic retention time and sulfide toxicity on ethanol and acetate oxidation in sulfate-reducing metal-precipitating fluidized-bed reactor. Biotechnology and bioengineering. vol 86. issue 3. 2004-12-21. PMID:15083513. |
partial acetate utilization was accompanied by decreased concentrations of dissolved sulfide (ds) and alkalinity in the effluent, and eventually resulted in process failure when hrt was decreased to 6.1 h (loading of 2.7 g ethanol l(-1) d(-1)). |
2004-12-21 |
2023-08-12 |
Not clear |
| Anna H Kaksonen, Peter D Franzmann, Jaakko A Puhakk. Effects of hydraulic retention time and sulfide toxicity on ethanol and acetate oxidation in sulfate-reducing metal-precipitating fluidized-bed reactor. Biotechnology and bioengineering. vol 86. issue 3. 2004-12-21. PMID:15083513. |
(ds) inhibition constants (k(i)) for ethanol and acetate oxidation were 248 mg s l(-1) and 356 mg s l(-1), respectively, and the corresponding k(i) values for h(2)s were 84 mg s l(-1) and 124 mg s l(-1). |
2004-12-21 |
2023-08-12 |
Not clear |
| G Lissens, H Klinke, W Verstraete, B Ahring, A B Thomse. Wet oxidation treatment of organic household waste enriched with wheat straw for simultaneous saccharification and fermentation into ethanol. Environmental technology. vol 25. issue 6. 2004-09-28. PMID:15369284. |
simultaneous saccharification and fermentation (ssf) of the treated waste at 10% ds by saccharomyces cerevisae yielded average ethanol concentrations of 16.5 to 22 g 1(-1) for enzyme loadings of 5 and 25 fpu g(-1) ds, respectively. |
2004-09-28 |
2023-08-12 |
Not clear |
| G Lissens, H Klinke, W Verstraete, B Ahring, A B Thomse. Wet oxidation treatment of organic household waste enriched with wheat straw for simultaneous saccharification and fermentation into ethanol. Environmental technology. vol 25. issue 6. 2004-09-28. PMID:15369284. |
the cellulose to ethanol conversion efficiency during ssf was 50, 62, 65 and 70% for a total enzyme loading of 5, 10, 15 and 25 fpu g(-1) ds, respectively. |
2004-09-28 |
2023-08-12 |
Not clear |
| Y Huang, Y Washio, M Hara, H Toyoda, I Koshiishi, T Toida, T Imanar. Simultaneous determination of dermatan sulfate and oversulfated dermatan sulfate in plasma by high-performance liquid chromatography with postcolumn fluorescence derivatization. Analytical biochemistry. vol 240. issue 2. 1996-11-27. PMID:8811915. |
ds and oversulfated ds were extracted from plasma by treating it with proteinase to remove plasma proteins and recovered with endogenous plasma glycosaminoglycans by ethanol precipitation. |
1996-11-27 |
2023-08-12 |
rat |
| P Pronko, S Zimatkin, A Kuzmic. Effect of aldehyde dehydrogenase and alcohol dehydrogenase inhibitors and ethanol on blood and liver ketone bodies in the rat. Polish journal of pharmacology. vol 46. issue 5. 1995-04-24. PMID:7894532. |
the effects of the aldehyde dehydrogenase (aldh) inhibitors: cyanamide (cy) and disulfiram (ds) and the alcohol dehydrogenase (adh) inhibitor, pyrazole (py) and the combination of these drugs with ethanol (et, 3.5 g/kg, ip 6 h before decapitation) on the concentrations of rat blood and liver ketone bodies were studied. |
1995-04-24 |
2023-08-12 |
rat |
| G Wong, K F Koehler, P Skolnick, Z Q Gu, S Ananthan, P Schönholzer, W Hunkeler, W Zhang, J M Coo. Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors. Journal of medicinal chemistry. vol 36. issue 13. 1993-07-19. PMID:8390574. |
however, only the putative ethanol antagonist 1 (ro 15-4513) displayed modest selectivity for the di site compared to other "diazepam-sensitive" (ds) bzr isoforms. |
1993-07-19 |
2023-08-12 |
Not clear |
| T J Phillips, E J Gallahe. Locomotor responses to benzodiazepines, barbiturates and ethanol in diazepam-sensitive (DS) and -resistant (DR) mice. Psychopharmacology. vol 107. issue 1. 1992-06-24. PMID:1589560. |
locomotor responses to benzodiazepines, barbiturates and ethanol in diazepam-sensitive (ds) and -resistant (dr) mice. |
1992-06-24 |
2023-08-11 |
mouse |
| H G Garg, E P Siebert, D A Swan. Isolation and some structure analyses of a copolymeric chondroitin sulfate-dermatan sulfate proteoglycan from post-burn, human hypertrophic scar. Carbohydrate research. vol 197. 1990-07-12. PMID:2346948. |
a d-glucuronic acid rich, copolymeric chondroitin sulfate (cs)-dermatan sulfate (ds) proteoglycan (pg) from post-burn hypertrophic scar tissue (hsc) was obtained by deae-cellulose chromatography and differential ethanol fractionation, and further purified on a sepharose cl-6b column. |
1990-07-12 |
2023-08-11 |
human |
| J Johnsen, A Stowell, T Stensrud, A Ripel, J Mørlan. A double-blind placebo controlled study of healthy volunteers given a subcutaneous disulfiram implantation. Pharmacology & toxicology. vol 66. issue 3. 1990-06-06. PMID:1970633. |
however, somewhat higher blood acetaldehyde concentrations were recorded after an oral ethanol dose (0.8 g/kg) in the ds group. |
1990-06-06 |
2023-08-11 |
human |
| J Johnsen, A Stowell, T Stensrud, A Ripel, J Mørlan. A double-blind placebo controlled study of healthy volunteers given a subcutaneous disulfiram implantation. Pharmacology & toxicology. vol 66. issue 3. 1990-06-06. PMID:1970633. |
in a longitudinal study with oral ethanol challenges after implanted ds, one of three healthy volunteers had a significant higher blood acetaldehyde concentration three weeks after the implantation, while no such tendency was found in any subject tested earlier or later in the post-implantation period. |
1990-06-06 |
2023-08-11 |
human |
| T Suzuki, Y Shiozaki, M Misaw. [Ethanol-induced discriminative stimulus properties in inbred rats with reference to aspirin, indomethacin and desipramine]. Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence. vol 24. issue 6. 1990-04-05. PMID:2627171. |
it is known that ethanol (etoh) possesses discriminative stimulus (ds) effects, but there has been no report on the effects of aspirin, indomethacin and desipramine on the ds properties of etoh. |
1990-04-05 |
2023-08-11 |
rat |
| J L Brind, K Chervinsky, J H Vogleman, N Orentreic. Radioimmunoassay of estrone sulfate in the serum of normal men after a chromatographic procedure that eliminates dehydroepiandrosterone sulfate interference. Steroids. vol 54. issue 1. 1989-12-20. PMID:2530662. |
fifty fresh-frozen normal male sera containing tritiated estrone sulfate (es) and dehydroepiandrosterone sulfate (ds) were extracted with ethanol after ether extraction of unconjugated steroids. |
1989-12-20 |
2023-08-11 |
Not clear |