| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Bacigaluppi, Giacomo Sferruzza, Erica Butti, Linda Ottoboni, Gianvito Martin. Endogenous neural precursor cells in health and disease. Brain research. vol 1730. 2021-06-07. PMID:31874148. |
neurogenesis persists in the adult brain of mammals in the subventricular zone (svz) of the lateral ventricles and in the subgranular zone (sgz) of the dentate gyrus (dg). |
2021-06-07 |
2023-08-13 |
Not clear |
| b' Thomas van Groen, Inga Kadish, Natalija Popovi\\xc4\\x87, Mar\\xc3\\xada Caballero Bleda, Beatriz Ba\\xc3\\xb1o-Otalora, Mar\\xc3\\xada Angeles Rol, Juan Antonio Madrid, Miroljub Popovi\\xc4\\x8. Widespread Doublecortin Expression in the Cerebral Cortex of the Frontiers in neuroanatomy. vol 15. 2021-05-18. PMID:33994960.' |
widespread doublecortin expression in the cerebral cortex of the it has been demonstrated that in adulthood rodents show newly born neurons in the subgranular layer (sgl) of the dentate gyrus (dg), and in the subventricular zone (svz). |
2021-05-18 |
2023-08-13 |
mouse |
| Rebecca M Ruddy, Daniel Derkach, Parvati Dadwal, Cindi M Morshea. Cranial irradiation in juvenile mice leads to early and sustained defects in the stem and progenitor cell pools and late cognitive impairments. Brain research. vol 1727. 2021-04-05. PMID:31715143. |
several rodent models have demonstrated that these cognitive deficits may be correlated with damage to neural progenitor cells in the subventricular zone (svz) and dentate gyrus (dg), the two neurogenic niches of the brain. |
2021-04-05 |
2023-08-13 |
mouse |
| Kyohei Kin, Takao Yasuhara, Masahiro Kameda, Yousuke Tomita, Michiari Umakoshi, Ken Kuwahara, Ittetsu Kin, Naoya Kidani, Jun Morimoto, Mihoko Okazaki, Tatsuya Sasaki, Naoki Tajiri, Cesario V Borlongan, Isao Dat. Cell encapsulation enhances antidepressant effect of the mesenchymal stem cells and counteracts depressive-like behavior of treatment-resistant depressed rats. Molecular psychiatry. vol 25. issue 6. 2021-03-09. PMID:30108315. |
the implantation of encapsulated mscs (emscs) into the lateral ventricle counteracted depressive-like behavior and enhanced the endogenous neurogenesis in the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus, whereas the implantation of mscs without encapsulation or the implantation of emscs into the striatum did not show such ameliorative effects. |
2021-03-09 |
2023-08-13 |
rat |
| Mohammad Badrul Anam, Shah Adil Ishtiyaq Ahmad, Mikiko Kudo, Arif Istiaq, Athary Abdulhaleem M Felemban, Naofumi Ito, Kunimasa Oht. Akhirin regulates the proliferation and differentiation of neural stem cells/progenitor cells at neurogenic niches in mouse brain. Development, growth & differentiation. vol 62. issue 2. 2020-12-21. PMID:31943155. |
the subventricular zone (svz) and the dentate gyrus (dg) of hippocampus in the mouse brain are two major neurogenic niches where neurogenesis is directed by numerous regulatory factors. |
2020-12-21 |
2023-08-13 |
mouse |
| Franco L Lombino, Mary Muhia, Jeffrey Lopez-Rojas, Monika S Brill, Edda Thies, Laura Ruschkies, David Lutz, Melanie Richter, Torben J Hausrat, André T Lopes, Francis J McNally, Irm Hermans-Borgmeyer, Jessica E M Dunleavy, Sabine Hoffmeister-Ullerich, Michael Frotscher, Thomas Misgeld, Michael R Kreutz, Froylan Calderon de Anda, Matthias Kneusse. The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis. Scientific reports. vol 9. issue 1. 2020-11-05. PMID:31685876. |
katanin p60 haploinsufficiency induced an accumulation of neuronal progenitors in the subventricular zone during corticogenesis, and impaired their proliferation in the adult hippocampus dentate gyrus (dg) subgranular zone. |
2020-11-05 |
2023-08-13 |
mouse |
| Rita Soares, Filipa F Ribeiro, Diogo M Lourenço, Rui S Rodrigues, João B Moreira, Ana M Sebastião, Vanessa A Morais, Sara Xapell. Isolation and Expansion of Neurospheres from Postnatal (P1-3) Mouse Neurogenic Niches. Journal of visualized experiments : JoVE. issue 159. 2020-10-07. PMID:32510488. |
in the postnatal and adult brain, nspcs are mainly present in two neurogenic niches: the subventricular zone (svz) lining the lateral ventricles and the subgranular zone of the hippocampal dentate gyrus (dg). |
2020-10-07 |
2023-08-13 |
mouse |
| Moritz D Brandt, Diana Krüger-Gerlach, Andreas Hermann, Anne K Meyer, Kwang-Soo Kim, Alexander Storc. Early Postnatal but Not Late Adult Neurogenesis Is Impaired in the Pitx3-Mutant Animal Model of Parkinson's Disease. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28883785. |
as dopamine plays an important role in regulating precursor cell proliferation, the loss of dopaminergic neurons in the substantia nigra (sn) in pd may be related to the reduced neurogenesis observed in the neurogenic regions of the adult brain: subventricular zone (svz) and dentate gyrus (dg). |
2020-10-01 |
2023-08-13 |
mouse |
| Yasuhisa Tamura, Yosky Kataok. PET imaging of neurogenic activity in the adult brain: Toward in vivo imaging of human neurogenesis. Neurogenesis (Austin, Tex.). vol 4. issue 1. 2020-09-30. PMID:28243610. |
neural stem cells are present in 2 neurogenic regions, the subventricular zone (svz) and the subgranular zone (sgz) of the hippocampal dentate gyrus (dg), and continue to generate new neurons throughout life. |
2020-09-30 |
2023-08-13 |
human |
| Jianfei Lu, Anatol Manaenko, Qin H. Targeting Adult Neurogenesis for Poststroke Therapy. Stem cells international. vol 2017. 2020-09-30. PMID:28808445. |
adult neurogenesis mainly occurs at the subventricular zone (svz) on the walls of the lateral ventricle and the subgranular zone (sgz) of the dentate gyrus (dg). |
2020-09-30 |
2023-08-13 |
Not clear |
| Rui S Rodrigues, Filipa F Ribeiro, Filipa Ferreira, Sandra H Vaz, Ana M Sebastião, Sara Xapell. Interaction between Cannabinoid Type 1 and Type 2 Receptors in the Modulation of Subventricular Zone and Dentate Gyrus Neurogenesis. Frontiers in pharmacology. vol 8. 2020-09-29. PMID:28848435. |
neurogenesis in the adult mammalian brain occurs mainly in two neurogenic niches, the subventricular zone (svz) and the subgranular zone (sgz) of the dentate gyrus (dg). |
2020-09-29 |
2023-08-13 |
Not clear |
| Wen Liu, Fulton T Crew. Persistent Decreases in Adult Subventricular and Hippocampal Neurogenesis Following Adolescent Intermittent Ethanol Exposure. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28855864. |
neurogenesis in hippocampal dentate gyrus (dg) and subventricular zone (svz) matures during adolescence to adult levels. |
2020-09-29 |
2023-08-13 |
rat |
| Filipa Fiel Ferreira, Filipa F Ribeiro, Rui S Rodrigues, Ana Maria Sebastião, Sara Xapell. Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:30546297. |
the adult mammalian brain can produce new neurons in a process called adult neurogenesis, which occurs mainly in the subventricular zone (svz) and in the hippocampal dentate gyrus (dg). |
2020-09-29 |
2023-08-13 |
rat |
| Zahra Shabani, Javad Mahmoudi, Fereshteh Farajdokht, Saeed Sadigh-Etegha. An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis. Archives of medical research. vol 51. issue 4. 2020-09-15. PMID:32279909. |
the subventricular zone (svz), lining the lateral ventricle, and the subgranular zone (sgz), which is in the dentate gyrus (dg) of the hippocampus, are the central regions of neurogenesis in the brain. |
2020-09-15 |
2023-08-13 |
Not clear |
| Naoki Haruyama, Kunihiko Sakumi, Atsuhisa Katogi, Daisuke Tsuchimoto, Gabriele De Luca, Margherita Bignami, Yusaku Nakabepp. 8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes. Progress in neurobiology. vol 180. 2020-06-29. PMID:31026482. |
8-oxoguanine accumulation significantly increased in nuclear dna, particularly in the dentate gyrus (dg), subventricular zone (svz) and major island of calleja (icjm) in middle-aged female to-dko mice. |
2020-06-29 |
2023-08-13 |
mouse |
| Yutaka Itokazu, Dongpei Li, Robert K Y. Intracerebroventricular Infusion of Gangliosides Augments the Adult Neural Stem Cell Pool in Mouse Brain. ASN neuro. vol 11. 2020-05-13. PMID:31635474. |
we previously reported that ganglioside gd3 is the predominant species in neural stem cells (nscs) and reduced postnatal nsc pools are observed in both the subventricular zone and dentate gyrus (dg) of gd3-synthase knockout (gd3s-ko) mouse brains. |
2020-05-13 |
2023-08-13 |
mouse |
| Jawad Fares, Zeina Bou Diab, Sanaa Nabha, Youssef Fare. Neurogenesis in the adult hippocampus: history, regulation, and prospective roles. The International journal of neuroscience. vol 129. issue 6. 2019-08-12. PMID:30433866. |
abbreviations ahn adult hippocampal neurogenesis akt protein kinase b bmp bone morphogenic protein brdu bromodeoxyuridine cns central nervous system dg dentate gyrus disc1 disrupted-in-schizophrenia 1 fgf-2 fibroblast growth factor 2 gaba gamma-aminobutyric acid mbd1 methyl-cpg-binding domain protein 1 mecp2 methyl-cpg-binding protein 2 mtor mammalian target of rapamycin nscs neural stem cells ob olfactory bulb; p21: cyclin-dependent kinase inhibitor 1 rbpj recombination signal binding protein for immunoglobulin kappa j region rms rostral migratory stream sgz subgranular zone shh sonic hedgehog sox2 sry (sex determining region y)-box 2 svz subventricular zone wnt3 wingless-type mouse mammary tumor virus. |
2019-08-12 |
2023-08-13 |
mouse |
| Naoya Murao, Shuzo Matsubara, Taito Matsuda, Hirofumi Noguchi, Tetsuji Mutoh, Masahiro Mutoh, Haruhiko Koseki, Masakazu Namihira, Kinichi Nakashim. Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain. Neuroscience research. vol 143. 2019-07-23. PMID:29859850. |
it is now generally known that adult neurogenesis in the hippocampal dentate gyrus (dg) and subventricular zone participates in various higher brain functions, such as learning and memory formation, olfactory discrimination and repair after brain injury. |
2019-07-23 |
2023-08-13 |
mouse |
| Tomasz Stępień, Sylwia Tarka, Dominik Chutorański, Paulina Felczak, Albert Acewicz, Teresa Wierzba-Bobrowic. Neurogenesis in adult human brain after hemorrhage and ischemic stroke. Folia neuropathologica. vol 56. issue 4. 2019-05-30. PMID:30786666. |
in the adult human brain, two neurogenic regions, the hippocampal dentate gyrus (dg) and the subventricular zone (svz) of lateral ventricles, have been identified. |
2019-05-30 |
2023-08-13 |
human |
| S Ray, M J Corenblum, A Anandhan, A Reed, F O Ortiz, D D Zhang, C A Barnes, L Madhava. A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells. Cell transplantation. vol 27. issue 4. 2019-05-17. PMID:29871525. |
using rats from multiple aging stages ranging from newborn to old age, and aging nrf2 knockout mice, we first determined that, in contrast with subventricular zone (svz) nspcs, nrf2 expression does not significantly affect overall dg nspc viability with age. |
2019-05-17 |
2023-08-13 |
mouse |