| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul A Christensen, Randall J Olsen, S Wesley Long, Sishir Subedi, James J Davis, Parsa Hodjat, Debbie R Walley, Jacob C Kinskey, Matthew Ojeda Saavedra, Layne Pruitt, Kristina Reppond, Madison N Shyer, Jessica Cambric, Ryan Gadd, Rashi M Thakur, Akanksha Batajoo, Regan Mangham, Sindy Pena, Trina Trinh, Prasanti Yerramilli, Marcus Nguyen, Robert Olson, Richard Snehal, Jimmy Gollihar, James M Musse. Delta Variants of SARS-CoV-2 Cause Significantly Increased Vaccine Breakthrough COVID-19 Cases in Houston, Texas. The American journal of pathology. 2021-12-05. PMID:34774517. |
patients infected with alpha and delta variants had several significant differences. |
2021-12-05 |
2023-08-13 |
Not clear |
| Siriruk Changrob, Yanbin Fu, Jenna J Guthmiller, Peter J Halfmann, Lei Li, Christopher T Stamper, Haley L Dugan, Molly Accola, William Rehrauer, Nai-Ying Zheng, Min Huang, Jiaolong Wang, Steven A Erickson, Henry A Utset, Hortencia M Graves, Fatima Amanat, D Noah Sather, Florian Krammer, Yoshihiro Kawaoka, Patrick C Wilso. Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike. mBio. 2021-12-04. PMID:34781736. |
despite this, we identified 12 neutralizing mabs against three distinct regions of the spike protein that neutralize sars-cov-2 and variants of concern (vocs), including b.1.1.7 (alpha), p.1 (gamma), and b.1.617.2 (delta). |
2021-12-04 |
2023-08-13 |
Not clear |
| Samuel Lebourgeois, Reyene Menidjel, Houssem Redha Chenane, Valentine Marie Ferré, Gilles Collin, Florence Damond, Romain Coppée, Yazdan Yazdanpanah, Jean-François Timsit, Nadhira Houhou-Fidouh, Diane Descamps, Charlotte Charpentier, Benoit Visseau. Alpha (B.1.1.7) and Delta (B.1.617.2 - AY.40) SARS-CoV-2 variants present strong neutralization decay at M4 post-vaccination and a faster replication rates than D614G (B.1) lineage. The Journal of infection. 2021-12-04. PMID:34808243. |
alpha (b.1.1.7) and delta (b.1.617.2 - ay.40) sars-cov-2 variants present strong neutralization decay at m4 post-vaccination and a faster replication rates than d614g (b.1) lineage. |
2021-12-04 |
2023-08-13 |
Not clear |
| Matteo Calcagnile, Tiziano Verri, Maurizio Salvatore Tredici, Patricia Forgez, Marco Alifano, Pietro Alifan. Codon usage, phylogeny and binding energy estimation predict the evolution of SARS-CoV-2. One health (Amsterdam, Netherlands). vol 13. 2021-12-04. PMID:34841034. |
first, codon usage analysis shows that the b.1.1.7 (alpha), b.1.351 (beta) and b.1.617.2 (delta) variants, similar in the use of codons, are also similar to a virus sampled in january 2020. |
2021-12-04 |
2023-08-13 |
Not clear |
| Iman Safari, Elahe Elah. Evolution of the SARS-CoV-2 genome and emergence of variants of concern. Archives of virology. 2021-12-03. PMID:34846601. |
variants designated g, alpha (b.1.1.7), beta (b.1.351), gamma (p.1), and delta (b.1.617.2) are important lineages that emerged sequentially and are considered variants of concern. |
2021-12-03 |
2023-08-13 |
Not clear |
| Iman Safari, Elahe Elah. Evolution of the SARS-CoV-2 genome and emergence of variants of concern. Archives of virology. 2021-12-03. PMID:34846601. |
while the alpha strain is sensitive to immune responses induced by earlier strains, the beta, gamma, and delta strains can escape antibody neutralization. |
2021-12-03 |
2023-08-13 |
Not clear |
| Kanyarat Phutthasophit, Darunee Buddhari, Piyawan Chinnawirotpisan, Khajohn Joonlasak, Wudtichai Manasatienkij, Angkana Huang, Thitiman Kaewkao, Narong Mahayos, Rotjana Khontong, Sopon Iamsirithaworn, Anthony R Jones, Aaron R Farmer, Stefan Fernandez, Chonticha Klungthon. Coding-Complete Genome Sequences of Alpha and Delta SARS-CoV-2 Variants from Kamphaeng Phet Province, Thailand, from May to July 2021. Microbiology resource announcements. vol 10. issue 48. 2021-12-03. PMID:34854728. |
coding-complete genome sequences of alpha and delta sars-cov-2 variants from kamphaeng phet province, thailand, from may to july 2021. |
2021-12-03 |
2023-08-13 |
Not clear |
| Kanyarat Phutthasophit, Darunee Buddhari, Piyawan Chinnawirotpisan, Khajohn Joonlasak, Wudtichai Manasatienkij, Angkana Huang, Thitiman Kaewkao, Narong Mahayos, Rotjana Khontong, Sopon Iamsirithaworn, Anthony R Jones, Aaron R Farmer, Stefan Fernandez, Chonticha Klungthon. Coding-Complete Genome Sequences of Alpha and Delta SARS-CoV-2 Variants from Kamphaeng Phet Province, Thailand, from May to July 2021. Microbiology resource announcements. vol 10. issue 48. 2021-12-03. PMID:34854728. |
we report coding-complete genome sequences of 44 severe acute respiratory syndrome coronavirus 2 (sars-cov-2) strains of the alpha and delta variants identified from patients in kamphaeng phet, thailand. |
2021-12-03 |
2023-08-13 |
Not clear |
| Cihan Yurdaydin, Onur Keskin, Esra Yurdcu, Aysun Çalişkan, Soner Önem, Fatih Karakaya, Çağdaş Kalkan, Ersin Karatayli, Senem Karatayli, Ingrid Choong, David Apelian, Christopher Koh, Theo Heller, Ramazan Idilman, Mithat A Bozdayi, Jeffrey S Glen. A Phase ii dose finding study of lonafarnib and ritonavir with or without interferon alpha for chronic delta hepatitis. Hepatology (Baltimore, Md.). 2021-12-03. PMID:34860418. |
a phase ii dose finding study of lonafarnib and ritonavir with or without interferon alpha for chronic delta hepatitis. |
2021-12-03 |
2023-08-13 |
Not clear |
| Deepali Gupta, Georgina K C Dowsett, Bharath K Mani, Kripa Shankar, Sherri Osborne-Lawrence, Nathan P Metzger, Brian Y H Lam, Giles S H Yeo, Jeffrey M Zigma. High Coexpression of the Ghrelin and LEAP2 Receptor GHSR With Pancreatic Polypeptide in Mouse and Human Islets. Endocrinology. vol 162. issue 10. 2021-12-02. PMID:34289060. |
islets represent an important site of direct action of the hormone ghrelin, with expression of the ghrelin receptor (growth hormone secretagogue receptor; ghsr) having been localized variably to alpha cells, beta cells, and/or somatostatin (sst)-secreting delta cells. |
2021-12-02 |
2023-08-13 |
mouse |
| Deepali Gupta, Georgina K C Dowsett, Bharath K Mani, Kripa Shankar, Sherri Osborne-Lawrence, Nathan P Metzger, Brian Y H Lam, Giles S H Yeo, Jeffrey M Zigma. High Coexpression of the Ghrelin and LEAP2 Receptor GHSR With Pancreatic Polypeptide in Mouse and Human Islets. Endocrinology. vol 162. issue 10. 2021-12-02. PMID:34289060. |
these data suggest that in addition to delta cells, beta cells, and alpha cells, pp-expressing pancreatic cells likely represent important direct targets for leap2 and/or ghrelin both in mice and humans. |
2021-12-02 |
2023-08-13 |
mouse |
| Rishi R Goel, Mark M Painter, Sokratis A Apostolidis, Divij Mathew, Wenzhao Meng, Aaron M Rosenfeld, Kendall A Lundgreen, Arnold Reynaldi, David S Khoury, Ajinkya Pattekar, Sigrid Gouma, Leticia Kuri-Cervantes, Philip Hicks, Sarah Dysinger, Amanda Hicks, Harsh Sharma, Sarah Herring, Scott Korte, Amy E Baxter, Derek A Oldridge, Josephine R Giles, Madison E Weirick, Christopher M McAllister, Moses Awofolaju, Nicole Tanenbaum, Elizabeth M Drapeau, Jeanette Dougherty, Sherea Long, Kurt D'Andrea, Jacob T Hamilton, Maura McLaughlin, Justine C Williams, Sharon Adamski, Oliva Kuthuru, Ian Frank, Michael R Betts, Laura A Vella, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Scott E Hensley, Miles P Davenport, Paul Bates, Eline T Luning Prak, Allison R Greenplate, E John Wherr. mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern. bioRxiv : the preprint server for biology. 2021-12-02. PMID:34462751. |
functional memory b cell responses, including those specific for the receptor binding domain (rbd) of the alpha (b.1.1.7), beta (b.1.351), and delta (b.1.617.2) variants, were also efficiently generated by mrna vaccination and continued to increase in frequency between 3 and 6 months post-vaccination. |
2021-12-02 |
2023-08-13 |
human |
| Chihiro Tani-Sassa, Yumi Iwasaki, Naoya Ichimura, Katsutoshi Nagano, Yuna Takatsuki, Sonoka Yuasa, Yuta Takahashi, Jun Nakajima, Kazunari Sonobe, Yoko Nukui, Hiroaki Takeuchi, Kousuke Tanimoto, Yukie Tanaka, Akinori Kimura, Shuji Tohd. Viral loads and profile of the patients infected with SARS-CoV-2 Delta, Alpha, or R.1 variants in Tokyo. Journal of medical virology. 2021-12-02. PMID:34825717. |
the r.1 variant (b.1.1.316) was responsible for most infections in march, replacing the previous variant (b.1.1.214); the alpha (b.1.1.7) variant caused most infections in april and may; and the delta variant (b.1.617.2) was the most prevalent in july and august. |
2021-12-02 |
2023-08-13 |
Not clear |
| Rita Jaafar, Celine Boschi, Sarah Aherfi, Audrey Bancod, Marion Le Bideau, Sophie Edouard, Philippe Colson, Henri Chahinian, Didier Raoult, Nouara Yahi, Jacques Fantini, Bernard La Scol. High Individual Heterogeneity of Neutralizing Activities against the Original Strain and Nine Different Variants of SARS-CoV-2. Viruses. vol 13. issue 11. 2021-12-01. PMID:34834983. |
in france, most cases were due to spike d641g-harbouring viruses that descended initially from the wuhan strain, then by the variant of b.1.160 lineage we called marseille-4 since the summer of 2020, which was followed by the alpha and beta variants in early 2021, then the delta variant currently. |
2021-12-01 |
2023-08-13 |
Not clear |
| Asish Kumar Ghosh, Marco Kaiser, Md Maruf Ahmed Molla, Tasnim Nafisa, Mahmuda Yeasmin, Rifat Hossain Ratul, Md Mohiuddin Sharif, Arifa Akram, Nur Hosen, Rashid Mamunur, Md Robed Amin, Alimul Islam, Md Ehsanul Hoque, Olfert Landt, Simon D Lytto. Molecular and Serological Characterization of the SARS-CoV-2 Delta Variant in Bangladesh in 2021. Viruses. vol 13. issue 11. 2021-12-01. PMID:34835116. |
the trend of higher viral load (lower cp values) among delta variants than in the alpha and beta variants was of borderline statistical significance ( |
2021-12-01 |
2023-08-13 |
Not clear |
| Rama Devudu Puligedda, Fetweh H Al-Saleem, Cristoph Wirblich, Chandana Devi Kattala, Marko Jović, Laura Geiszler, Himani Devabhaktuni, Giora Z Feuerstein, Matthias J Schnell, Markus Sack, Lawrence L Livornese, Scott K Dessai. A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue. Diagnostics (Basel, Switzerland). vol 11. issue 11. 2021-11-30. PMID:34829439. |
four variants of concern (vocs) have been designated by the centers for disease control and prevention (cdc), namely, b.1.617.2 (delta), b.1.1.7 (alpha), b.1.351 (beta), and p.1 (gamma), although the last three have been downgraded to variants being monitored (vbms). |
2021-11-30 |
2023-08-13 |
Not clear |
| Rama Devudu Puligedda, Fetweh H Al-Saleem, Cristoph Wirblich, Chandana Devi Kattala, Marko Jović, Laura Geiszler, Himani Devabhaktuni, Giora Z Feuerstein, Matthias J Schnell, Markus Sack, Lawrence L Livornese, Scott K Dessai. A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue. Diagnostics (Basel, Switzerland). vol 11. issue 11. 2021-11-30. PMID:34829439. |
when used in a sandwich elisa, these mabs sort these important sars-cov-2 variants into three diagnostic categories, namely, (1) delta, (2) alpha or gamma, and (3) beta. |
2021-11-30 |
2023-08-13 |
Not clear |
| Robert Hohan, Petre Milu, Simona Paraschiv, Corina Casangiu, Andreea Tudor, Ovidiu Vlaicu, Leontina Banica, Marius Surleac, Dragos Florea, Dan Otele. The Predictive Value of Mutation Screening for Anticipating COVID-19 Waves. Pathogens (Basel, Switzerland). vol 10. issue 11. 2021-11-30. PMID:34832619. |
the appearance of the alpha and delta strains has been associated with substantial increases in the number of covid-19 cases and associated deaths. |
2021-11-30 |
2023-08-13 |
Not clear |
| Robert Hohan, Petre Milu, Simona Paraschiv, Corina Casangiu, Andreea Tudor, Ovidiu Vlaicu, Leontina Banica, Marius Surleac, Dragos Florea, Dan Otele. The Predictive Value of Mutation Screening for Anticipating COVID-19 Waves. Pathogens (Basel, Switzerland). vol 10. issue 11. 2021-11-30. PMID:34832619. |
the positive predictive value (ppv) of 4/5 markers was over 95% for the detection of alpha and delta variants. |
2021-11-30 |
2023-08-13 |
Not clear |
| Robert Hohan, Petre Milu, Simona Paraschiv, Corina Casangiu, Andreea Tudor, Ovidiu Vlaicu, Leontina Banica, Marius Surleac, Dragos Florea, Dan Otele. The Predictive Value of Mutation Screening for Anticipating COVID-19 Waves. Pathogens (Basel, Switzerland). vol 10. issue 11. 2021-11-30. PMID:34832619. |
by estimating the prevalence of the alpha and delta strains using genotyping assays and fitting the data to a mathematical model, a five week period between the point of exponential growth of variant prevalence and a drastic increase in case numbers was found. |
2021-11-30 |
2023-08-13 |
Not clear |