| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gi Uk Jeong, Gun Young Yoon, Hyun Woo Moon, Wooseong Lee, Insu Hwang, Haesoo Kim, Kyun-Do Kim, Chonsaeng Kim, Dae-Gyun Ahn, Bum-Tae Kim, Seong-Jun Kim, Young-Chan Kwo. Comparison of Plaque Size, Thermal Stability, and Replication Rate among SARS-CoV-2 Variants of Concern. Viruses. vol 14. issue 1. 2022-01-22. PMID:35062259. |
the mean plaque size of beta was the largest, followed by those of gamma, delta, and alpha. |
2022-01-22 |
2023-08-13 |
Not clear |
| Pushpendra Singh, Kuldeep Sharma, Priyanka Singh, Anudita Bhargava, Sanjay Singh Negi, Pratibha Sharma, Mayuri Bhise, Manish Kumar Tripathi, Atul Jindal, Nitin M Nagarka. Genomic characterization unravelling the causative role of SARS-CoV-2 Delta variant of lineage B.1.617.2 in 2nd wave of COVID-19 pandemic in Chhattisgarh, India. Microbial pathogenesis. 2022-01-22. PMID:35065253. |
the significant predominance of the sars-cov-2 variant of concern (voc), delta (lineage b.1.617.2) identified in sixty-four (77.1%) cases in contrast to b.1 and its sublineage in eleven (13.2%), variant under monitoring (vum), kappa (lineage b.1.617.1) in five (6.0%) and another voc alpha (lineage b.1.1.7) in three (3.6%) cases respectively (p < 0.05, χ |
2022-01-22 |
2023-08-13 |
Not clear |
| Hannah W Despres, Margaret G Mills, David J Shirley, Madaline M Schmidt, Meei-Li Huang, Pavitra Roychoudhury, Keith R Jerome, Alexander L Greninger, Emily A Bruc. Measuring infectious SARS-CoV-2 in clinical samples reveals a higher viral titer:RNA ratio for Delta and Epsilon vs. Alpha variants. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 5. 2022-01-21. PMID:35058348. |
measuring infectious sars-cov-2 in clinical samples reveals a higher viral titer:rna ratio for delta and epsilon vs. alpha variants. |
2022-01-21 |
2023-08-13 |
Not clear |
| Lianghui Zhang, Soumajit Dutta, Shiqin Xiong, Matthew Chan, Kui K Chan, Timothy M Fan, Keith L Bailey, Matthew Lindeblad, Laura M Cooper, Lijun Rong, Anthony F Gugliuzza, Diwakar Shukla, Erik Procko, Jalees Rehman, Asrar B Mali. Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants. Nature chemical biology. 2022-01-20. PMID:35046611. |
using molecular dynamics simulations and functional assays, we show that three amino acid substitutions in an engineered soluble ace2 protein markedly augmented the affinity for the s protein of the sars-cov-2 wa-1/2020 isolate and multiple vocs: b.1.1.7 (alpha), b.1.351 (beta), p.1 (gamma) and b.1.617.2 (delta). |
2022-01-20 |
2023-08-13 |
mouse |
| Warish Ahmed, Aaron Bivins, Wendy J M Smith, Suzanne Metcalfe, Mikayla Stephens, Amy V Jennison, Frederick A J Moore, Jayden Bourke, Sanmarie Schlebusch, Jamie McMahon, Glen Hewitson, Son Nguyen, Jean Barcelon, Greg Jackson, Jochen F Mueller, John Ehret, Ian Hosegood, Wei Tian, Haofei Wang, Lin Yang, Paul Bertsch, Josh Tynan, Kevin V Thomas, Kyle Bibby, Tyson E Graber, Ryan Ziels, Stuart L Simpso. Detection of the Omicron (B.1.1.529) variant of SARS-CoV-2 in aircraft wastewater. The Science of the total environment. 2022-01-20. PMID:35051459. |
the genome of the omicron voc contains more than 50 mutations, many of which have been associated with increased transmissibility, differing disease severity, and potential to evade immune responses developed for previous vocs such as alpha and delta. |
2022-01-20 |
2023-08-13 |
Not clear |
| Karl R Franke, Robert Isett, Alan Robbins, Carrie Paquette-Straub, Craig A Shapiro, Mary M Lee, Erin L Crowge. Genomic surveillance of SARS-CoV-2 in the state of Delaware reveals tremendous genomic diversity. PloS one. vol 17. issue 1. 2022-01-19. PMID:35045124. |
a total of 411 samples belonging to the alpha 20i/501y.v1 (b.1.1.7) strain of concern were identified, as well as one sample belonging to beta 20h/501.v2 (b.1.351), thirteen belonging to epsilon 20c/s:452r (b.1.427/b.1.429), two belonging to delta 20a/s:478k (b.1.617.2), and 15 belonging to gamma 20j/501y.v3 (p.1). |
2022-01-19 |
2023-08-13 |
Not clear |
| Duygu Beduk, José Ilton de Oliveira Filho, Tutku Beduk, Duygu Harmanci, Figen Zihnioglu, Candan Cicek, Ruchan Sertoz, Bilgin Arda, Tuncay Goksel, Kutsal Turhan, Khaled Nabil Salama, Suna Timu. 'All In One' SARS-CoV-2 variant recognition platform: Machine learning-enabled point of care diagnostics. Biosensors & bioelectronics: X. vol 10. 2022-01-17. PMID:35036904. |
clinical study has been conducted with nasopharyngeal swabs from 63 patients having alpha (b.1.1.7), beta (b.1.351), delta (b.1.617.2) variants, patients without mutation and negative patients. |
2022-01-17 |
2023-08-13 |
Not clear |
| Bo-Seong Jeong, Jeong Seok Cha, Insu Hwang, Uijin Kim, Jared Adolf-Bryfogle, Brian Coventry, Hyun-Soo Cho, Kyun-Do Kim, Byung-Ha O. Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants. mAbs. vol 14. issue 1. 2022-01-15. PMID:35030983. |
subsequently, through experimental affinity enhancement and computational affinity maturation, it was further developed to bind the rbd of all concerning sars-cov-2 variants, sars-cov-1 and pangolin coronavirus with pico-molar binding affinities, consistently exhibited strong neutralization activity against wild-type sars-cov-2 and the alpha and delta variants. |
2022-01-15 |
2023-08-13 |
Not clear |
| Jerome Hadjadj, Delphine Planas, Amani Ouedrani, Solene Buffier, Laure Delage, Yann Nguyen, Timothée Bruel, Marie-Claude Stolzenberg, Isabelle Staropoli, Natalia Ermak, Laure Macraigne, Caroline Morbieu, Soledad Henriquez, David Veyer, Hélène Péré, Marion Casadevall, Luc Mouthon, Frederic Rieux-Laucat, Lucienne Chatenoud, Olivier Schwartz, Benjamin Terrie. Immunogenicity of BNT162b2 vaccine against the Alpha and Delta variants in immunocompromised patients with systemic inflammatory diseases. Annals of the rheumatic diseases. 2022-01-13. PMID:35022159. |
immunogenicity of bnt162b2 vaccine against the alpha and delta variants in immunocompromised patients with systemic inflammatory diseases. |
2022-01-13 |
2023-08-13 |
Not clear |
| Miray Yılmaz Çelebi, Elif Kıymet, Elif Böncüoğlu, Şahika Şahinkaya, Ela Cem, Mine Düzgöl, Aybüke Akaslan Kara, Fahri Yüce Ayhan, Süleyman Nuri Bayram, İlker Devri. Evaluation of childhood hospitalization rates and degree of severity of SARS-CoV-2 variants including of the B.1.1.7 (Alpha), B.1.315/P.1 (Beta/Gamma), and B.1.617.2 (Delta). Journal of medical virology. 2022-01-12. PMID:35018660. |
evaluation of childhood hospitalization rates and degree of severity of sars-cov-2 variants including of the b.1.1.7 (alpha), b.1.315/p.1 (beta/gamma), and b.1.617.2 (delta). |
2022-01-12 |
2023-08-13 |
Not clear |
| Miray Yılmaz Çelebi, Elif Kıymet, Elif Böncüoğlu, Şahika Şahinkaya, Ela Cem, Mine Düzgöl, Aybüke Akaslan Kara, Fahri Yüce Ayhan, Süleyman Nuri Bayram, İlker Devri. Evaluation of childhood hospitalization rates and degree of severity of SARS-CoV-2 variants including of the B.1.1.7 (Alpha), B.1.315/P.1 (Beta/Gamma), and B.1.617.2 (Delta). Journal of medical virology. 2022-01-12. PMID:35018660. |
severe acute respiratory syndrome coronavirus 2 is appearing with an increasing number of variants day by day, this study aimed to determine the effect of b.1.1.7 (alpha), b.1.351 (beta), p.1 (gamma), and b.1.617.2 (delta) variants on hospitalization rates. |
2022-01-12 |
2023-08-13 |
Not clear |
| María Eva González-Trujano, Felix Krengel, Ricardo Reyes-Chilpa, Benjamín Villasana-Salazar, José David González-Gómez, Fernando Santos-Valencia, Edgar Urbina-Trejo, Adrián Martínez, David Martínez-Varga. Tabernaemontana arborea and ibogaine induce paroxysmal EEG activity in freely moving mice: involvement of serotonin 5-HT Neurotoxicology. 2022-01-09. PMID:34999156. |
promoted a significant increase in the relative power of the delta band and a significant reduction in alpha band values, denoting a cns depressant effect. |
2022-01-09 |
2023-08-13 |
mouse |
| Jéromine Klingler, Gregory S Lambert, Vincenza Itri, Sean Liu, Juan C Bandres, Gospel Enyindah-Asonye, Xiaomei Liu, Viviana Simon, Charles R Gleason, Giulio Kleiner, Hsin-Ping Chiu, Chuan-Tien Hung, Shreyas Kowdle, Fatima Amanat, Benhur Lee, Susan Zolla-Pazner, Chitra Upadhyay, Catarina E Hio. Detection of Antibody Responses Against SARS-CoV-2 in Plasma and Saliva From Vaccinated and Infected Individuals. Frontiers in immunology. vol 12. 2022-01-06. PMID:34987505. |
neutralization titers against the initial wa1 (d614g), b.1.1.7 (alpha) and b.1.617.2 (delta) strains were similar but lower against the b.1.351 (beta) strain. |
2022-01-06 |
2023-08-13 |
Not clear |
| Lidewij W Rümke, Femke C Groenveld, Yvonne M G van Os, Patrique Praest, Anniek A N Tanja, Dorien T C M de Jong, Jori Symons, Rob Schuurman, Tessa Reinders, L Marije Hofstra, Stefan Nierkens, Steven F T Thijsen, Michiel Heron, Robert-Jan Lebbink, Jeffrey M Beekman, Monique Nijhuis, Annemarie M J Wensin. In-depth Characterization of Vaccine Breakthrough Infections With SARS-CoV-2 Among Health Care Workers in a Dutch Academic Medical Center. Open forum infectious diseases. vol 9. issue 1. 2022-01-06. PMID:34988250. |
these breakthrough infections presented with regular b.1.1.7 (alpha) and b.1.617.2 (delta) variants and high viral loads, despite normal vaccine-induced b- and t-cell immune responses detected by live virus neutralization assays and elispot. |
2022-01-06 |
2023-08-13 |
Not clear |
| Giulietta Maruggi, Corey P Mallett, Jason W Westerbeck, Tiffany Chen, Giuseppe Lofano, Kristian Friedrich, Lin Qu, Jennifer Tong Sun, Josie McAuliffe, Amey Kanitkar, Kathryn T Arrildt, Kai-Fen Wang, Ian McBee, Deborah McCoy, Rebecca Terry, Alison Rowles, Maia Araujo Abrahim, Michael A Ringenberg, Malcolm J Gains, Catherine Spickler, Xuping Xie, Jing Zou, Pei-Yong Shi, Taru Dutt, Marcela Henao-Tamayo, Izabela Ragan, Richard A Bowen, Russell Johnson, Sandra Nuti, Kate Luisi, Jeffrey B Ulmer, Ann-Muriel Steff, Rashmi Jalah, Sylvie Bertholet, Alan H Stokes, Dong Y. A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models. Molecular therapy : the journal of the American Society of Gene Therapy. 2022-01-06. PMID:34990810. |
in mice, one immunization with the sam vaccine elicited a robust spike-specific antibody response, which was further boosted by a second immunization, and effectively neutralized the matched sars-cov-2 wuhan strain as well as b.1.1.7 (alpha), b.1.351 (beta) and b.1.617.2 (delta) variants. |
2022-01-06 |
2023-08-13 |
mouse |
| Dongyan Xiong, Xiaoxu Zhang, Mengjuan Shi, Nuo Wang, Ping He, Zhuo Dong, Jie Zhong, Jing Luo, Yong Wang, Junping Yu, Hongping We. Developing an Amplification Refractory Mutation System-Quantitative Reverse Transcription-PCR Assay for Rapid and Sensitive Screening of SARS-CoV-2 Variants of Concern. Microbiology spectrum. 2022-01-05. PMID:34985323. |
among them, mutations c1709a (a change of c to a at position 1709) and c56g, respectively, were found in more than 99% of the genomes of alpha and delta variants and were specific to them. |
2022-01-05 |
2023-08-13 |
Not clear |
| Dongyan Xiong, Xiaoxu Zhang, Mengjuan Shi, Nuo Wang, Ping He, Zhuo Dong, Jie Zhong, Jing Luo, Yong Wang, Junping Yu, Hongping We. Developing an Amplification Refractory Mutation System-Quantitative Reverse Transcription-PCR Assay for Rapid and Sensitive Screening of SARS-CoV-2 Variants of Concern. Microbiology spectrum. 2022-01-05. PMID:34985323. |
the assay can detect as little as 1 copy/μl of the vocs, and the results for identifying alpha and delta variants in clinical samples by the arms-rt-qpcr assay showed 100% agreement with the results using sequencing-based methods. |
2022-01-05 |
2023-08-13 |
Not clear |
| Dongyan Xiong, Xiaoxu Zhang, Mengjuan Shi, Nuo Wang, Ping He, Zhuo Dong, Jie Zhong, Jing Luo, Yong Wang, Junping Yu, Hongping We. Developing an Amplification Refractory Mutation System-Quantitative Reverse Transcription-PCR Assay for Rapid and Sensitive Screening of SARS-CoV-2 Variants of Concern. Microbiology spectrum. 2022-01-05. PMID:34985323. |
therefore, the arms-rt-qpcr assay could be used for screening the two highly concerning variants alpha and delta by normal pcr laboratories in airports and in hospitals and other health-related organizations. |
2022-01-05 |
2023-08-13 |
Not clear |
| David W Eyre, Donald Taylor, Mark Purver, David Chapman, Tom Fowler, Koen B Pouwels, A Sarah Walker, Tim E A Pet. Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants. The New England journal of medicine. 2022-01-05. PMID:34986294. |
effect of covid-19 vaccination on transmission of alpha and delta variants. |
2022-01-05 |
2023-08-13 |
Not clear |
| Paul Elliott, David Haw, Haowei Wang, Oliver Eales, Caroline E Walters, Kylie E C Ainslie, Christina Atchison, Claudio Fronterre, Peter J Diggle, Andrew J Page, Alexander J Trotter, Sophie J Prosolek, Deborah Ashby, Christl A Donnelly, Wendy Barclay, Graham Taylor, Graham Cooke, Helen Ward, Ara Darzi, Steven Rile. Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant. Science (New York, N.Y.). vol 374. issue 6574. 2021-12-30. PMID:34726481. |
during june and july 2021, we observed sustained exponential growth with an average doubling time of 25 days, driven by complete replacement of the alpha variant by delta and by high prevalence at younger, less-vaccinated ages. |
2021-12-30 |
2024-01-07 |
Not clear |