| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian J H von Wintersdorff, Jozef Dingemans, Lieke B van Alphen, Petra F G Wolffs, Brian M J W van der Veer, Christian J P A Hoebe, Paul H M Savelkou. Infections with the SARS-CoV-2 Delta variant exhibit fourfold increased viral loads in the upper airways compared to Alpha or non-variants of concern. Scientific reports. vol 12. issue 1. 2022-08-17. PMID:35978025. |
infections with the sars-cov-2 delta variant exhibit fourfold increased viral loads in the upper airways compared to alpha or non-variants of concern. |
2022-08-17 |
2023-08-14 |
Not clear |
| Christian J H von Wintersdorff, Jozef Dingemans, Lieke B van Alphen, Petra F G Wolffs, Brian M J W van der Veer, Christian J P A Hoebe, Paul H M Savelkou. Infections with the SARS-CoV-2 Delta variant exhibit fourfold increased viral loads in the upper airways compared to Alpha or non-variants of concern. Scientific reports. vol 12. issue 1. 2022-08-17. PMID:35978025. |
here, we have compared the viral load in 16,185 samples that were obtained in periods during which non-voc, the alpha (b.1.1.7) or delta variant (b.1.617.2) were dominant as evidenced by genomic surveillance. |
2022-08-17 |
2023-08-14 |
Not clear |
| Christian J H von Wintersdorff, Jozef Dingemans, Lieke B van Alphen, Petra F G Wolffs, Brian M J W van der Veer, Christian J P A Hoebe, Paul H M Savelkou. Infections with the SARS-CoV-2 Delta variant exhibit fourfold increased viral loads in the upper airways compared to Alpha or non-variants of concern. Scientific reports. vol 12. issue 1. 2022-08-17. PMID:35978025. |
we found that the delta variant contained about fourfold higher viral loads across all age groups compared to the non-voc or alpha variants, which is significantly lower than reported earlier. |
2022-08-17 |
2023-08-14 |
Not clear |
| Christian J H von Wintersdorff, Jozef Dingemans, Lieke B van Alphen, Petra F G Wolffs, Brian M J W van der Veer, Christian J P A Hoebe, Paul H M Savelkou. Infections with the SARS-CoV-2 Delta variant exhibit fourfold increased viral loads in the upper airways compared to Alpha or non-variants of concern. Scientific reports. vol 12. issue 1. 2022-08-17. PMID:35978025. |
interestingly, the increased viral load for the delta variant seemed to be age-dependent, regardless of sex, as the viral load was about 14-fold higher for delta compared to the non-voc or alpha variant in age group 0-20 years and fourfold higher in age group 21-40 years, while there was no difference in viral load between variants in age groups 41-60 and 61+ years, most likely as a consequence of a higher degree of vaccination in the older age groups. |
2022-08-17 |
2023-08-14 |
Not clear |
| J Panovska-Griffiths, B Swallow, R Hinch, J Cohen, K Rosenfeld, R M Stuart, L Ferretti, F Di Lauro, C Wymant, A Izzo, W Waites, R Viner, C Bonell, C Fraser, D Klein, C C Ker. Statistical and agent-based modelling of the transmissibility of different SARS-CoV-2 variants in England and impact of different interventions. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. vol 380. issue 2233. 2022-08-15. PMID:35965458. |
the english sars-cov-2 epidemic has been affected by the emergence of new viral variants such as b.1.177, alpha and delta, and changing restrictions. |
2022-08-15 |
2023-08-14 |
Not clear |
| J Panovska-Griffiths, B Swallow, R Hinch, J Cohen, K Rosenfeld, R M Stuart, L Ferretti, F Di Lauro, C Wymant, A Izzo, W Waites, R Viner, C Bonell, C Fraser, D Klein, C C Ker. Statistical and agent-based modelling of the transmissibility of different SARS-CoV-2 variants in England and impact of different interventions. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. vol 380. issue 2233. 2022-08-15. PMID:35965458. |
we used statistical models and the agent-based model covasim, in june 2021, to estimate b.1.177 to be 20% more transmissible than the wild type, alpha to be 50-80% more transmissible than b.1.177 and delta to be 65-90% more transmissible than alpha. |
2022-08-15 |
2023-08-14 |
Not clear |
| Li-Jun Duan, Wen-Guo Jiang, Zhuang-Ye Wang, Lin Yao, Ka-Li Zhu, Qing-Chuan Meng, Bao-Shan Wang, Li-Bo Li, Guo-Lin Wang, Mai-Juan M. Neutralizing immunity against SARS-CoV-2 Omicron BA.1 by infection and vaccination. iScience. 2022-08-15. PMID:35966041. |
both sera from convalescent patients over three months after infection and two-dose bbibp-corv or coronavac vaccine recipients barely inhibited ba.1, less effectively neutralized beta and delta, and moderately neutralized alpha. |
2022-08-15 |
2023-08-14 |
Not clear |
| Carmela De Marco, Claudia Veneziano, Alice Massacci, Matteo Pallocca, Nadia Marascio, Angela Quirino, Giorgio Settimo Barreca, Aida Giancotti, Luigia Gallo, Angelo Giuseppe Lamberti, Barbara Quaresima, Gianluca Santamaria, Flavia Biamonte, Stefania Scicchitano, Enrico Maria Trecarichi, Alessandro Russo, Daniele Torella, Aldo Quattrone, Carlo Torti, Giovanni Matera, Caterina De Filippo, Francesco Saverio Costanzo, Giuseppe Vigliett. Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy. Frontiers in microbiology. vol 13. 2022-08-15. PMID:35966675. |
our results indicated that b.1 and alpha were the only circulating lineages in calabria in march 2021; while alpha remained the most common variant between april 2021 and may 2021 (90 and 73%, respectively), we observed a concomitant decrease in b.1 cases and appearance of gamma cases (6 and 21%, respectively); c.36.3 and delta appeared in june 2021 (6 and 3%, respectively); delta became dominant in july 2021 while alpha continued to reduce (46 and 48%, respectively). |
2022-08-15 |
2023-08-14 |
Not clear |
| Carmela De Marco, Claudia Veneziano, Alice Massacci, Matteo Pallocca, Nadia Marascio, Angela Quirino, Giorgio Settimo Barreca, Aida Giancotti, Luigia Gallo, Angelo Giuseppe Lamberti, Barbara Quaresima, Gianluca Santamaria, Flavia Biamonte, Stefania Scicchitano, Enrico Maria Trecarichi, Alessandro Russo, Daniele Torella, Aldo Quattrone, Carlo Torti, Giovanni Matera, Caterina De Filippo, Francesco Saverio Costanzo, Giuseppe Vigliett. Dynamics of Viral Infection and Evolution of SARS-CoV-2 Variants in the Calabria Area of Southern Italy. Frontiers in microbiology. vol 13. 2022-08-15. PMID:35966675. |
prediction analysis of the effects of mutations on the immune response (i.e., binding to class i mhc and/or recognition of t cells) indicated that t29i in b.1 variant; a701s in alpha variant; and t19r in delta variant were predicted to impair binding to class i mhc whereas the mutations a67s identified in alpha; e484k identified in gamma; and e156g and Δf157/r158 identified in delta were predicted to impair recognition by t cells. |
2022-08-15 |
2023-08-14 |
Not clear |
| Koji Tsuchiya, Norio Yamamoto, Yoshie Hosaka, Mitsuru Wakita, Makoto Hiki, Yasushi Matsushita, Hirotake Mori, Satoshi Hori, Shigeki Misawa, Takashi Miida, Shuko Nojiri, Kazuhisa Takahashi, Toshio Naito, Yoko Tab. Molecular characterization of SARS-CoV-2 detected in Tokyo, Japan during five waves: Identification of the amino acid substitutions associated with transmissibility and severity. Frontiers in microbiology. vol 13. 2022-08-15. PMID:35966679. |
these mutations include s: m153t, n: p151l, nsp3: s543p, nsp5: p108s, and nsp12: a423v in b.1.1.284; s: w152l and e484k in r.1; s: h69del, v70del, and n501y in the alpha strain; s: l452r, t478k, and p681r in the delta strain. |
2022-08-15 |
2023-08-14 |
Not clear |
| Antonella Mencacci, Alessio Gili, Barbara Camilloni, Giulia Bicchieraro, Roberta Spaccapelo, Carla Bietta, Fabrizio Stracc. Immediate reinfection with Omicron variant after clearance of a previous SARS-CoV-2 infection. Journal of infection and public health. vol 15. issue 9. 2022-08-13. PMID:35963101. |
immediate reinfection was not observed for any other combination of variants, including delta over alpha variant and ba.2 over ba.1 omicron lineage. |
2022-08-13 |
2023-08-14 |
Not clear |
| Aline Miranda Scovino, Elizabeth Chen Dahab, Gustavo Fioravanti Vieira, Leonardo Freire-de-Lima, Celio Geraldo Freire-de-Lima, Alexandre Morro. SARS-CoV-2's Variants of Concern: A Brief Characterization. Frontiers in immunology. vol 13. 2022-08-12. PMID:35958548. |
the severe acute respiratory syndrome coronavirus 2 (sars-cov-2) disclose the variants of concern (voc) including alpha (b.1.1.7), beta (b.1.351), gamma (p1), delta (b.1.617.2), and omicron (b.1.1.529). |
2022-08-12 |
2023-08-14 |
Not clear |
| Yuxuan Zhang, Zhiwei Huang, Jiajie Zhu, Chaonan Li, Zhongbiao Fang, Keda Chen, Yanjun Zhan. An updated review of SARS-CoV-2 detection methods in the context of a novel coronavirus pandemic. Bioengineering & translational medicine. 2022-08-09. PMID:35942232. |
however, because of the emergence of strongly infectious mutants of the new coronavirus, such as alpha (b.1.1.7), delta (b.1.617.2), and omicron (b.1.1.529), the need for the specific detection of mutant strains is also increasing. |
2022-08-09 |
2023-08-14 |
Not clear |
| Anamica Hossain, Shammi Akter Trishna, Alfi Anjum Rashid, Sabik Khair, A S M Rubayet Ul Ala. Unique mutations in SARS-CoV-2 omicron subvariants' non-spike proteins: Potential impact on viral pathogenesis and host immune evasion. Microbial pathogenesis. 2022-08-09. PMID:35944840. |
the major five variants of concern (vocs) are alpha (b.1.1.7), beta (b.1.315), gamma (p.1), delta (b.1.617.2), and omicron (b.1.1.529.*/ba.*). |
2022-08-09 |
2023-08-14 |
Not clear |
| Romain Volle, Luca Murer, Anthony Petkidis, Vardan Andriasyan, Alessandro Savi, Cornelia Bircher, Nicole Meili, Lucy Fischer, Daniela Policarpo Sequeira, Daniela Katharina Mark, Alfonso Gomez-Gonzalez, Urs F Grebe. Methylene blue, Mycophenolic acid, Posaconazole, and Niclosamide inhibit SARS-CoV-2 Omicron variant BA.1 infection of human airway epithelial organoids. Current research in microbial sciences. vol 3. 2022-08-08. PMID:35935678. |
mb, mpa, pos, and niclo are known to block infection of human nasal and bronchial airway epithelial explant cultures (haeec) with the wuhan strain, and four variants of concern (voc), alpha (b.1.1.7), beta (b.1.351), gamma (b.1.1.28), delta (b.1.617.2) ( |
2022-08-08 |
2023-08-14 |
human |
| M R Smallman-Raynor, A D Clif. Spatial growth rate of emerging SARS-CoV-2 lineages in England, September 2020-December 2021. Epidemiology and infection. vol 150. 2022-08-05. PMID:35855577. |
spatial growth of the omicron (b.1.1.529 and ba) variant was found to be 2.81× faster than the delta (b.1.617.2 and ay) variant and 3.76× faster than the alpha (b.1.1.7 and q) variant. |
2022-08-05 |
2023-10-07 |
Not clear |
| Seema Mishr. Computational Structural and Functional Analyses of ORF10 in Novel Coronavirus SARS-CoV-2 Variants to Understand Evolutionary Dynamics. Evolutionary bioinformatics online. vol 18. 2022-08-01. PMID:35909986. |
it was observed that its nucleotide sequence is 100% identical in the sars-cov-2 genomes sourced worldwide, even in the recent-most vocs and vois of b.1.1.529 (omicron), b.1.617 (delta), b.1.1.7 (alpha), b.1.351 (beta), and p.1 (gamma) lineages, implicating its constant nature throughout the evolution of deadly variants. |
2022-08-01 |
2023-08-14 |
Not clear |
| Ron Sender, Yinon Bar-On, Sang Woo Park, Elad Noor, Jonathan Dushoff, Ron Mil. The unmitigated profile of COVID-19 infectiousness. eLife. vol 11. 2022-08-01. PMID:35913120. |
although unmitigated transmission data is lacking for variants of concern (voc), previous analyses suggest that the alpha and delta variants have faster within-host kinetics, which we extrapolate to crude estimates of variant-specific unmitigated generation intervals. |
2022-08-01 |
2023-08-14 |
Not clear |
| Nadim Sharif, Khalid J Alzahrani, Shamsun Nahar Ahmed, Afsana Khan, Hamsa Jameel Banjer, Fuad M Alzahrani, Anowar Khasru Parvez, Shuvra Kanti De. Genomic surveillance, evolution and global transmission of SARS-CoV-2 during 2019-2022. PloS one. vol 17. issue 8. 2022-08-01. PMID:35913920. |
voc delta (66%) was the most prevalent variant followed by voc alpha (18%), voc omicron (13%), voc gamma (2%) and voc beta (1%), respectively. |
2022-08-01 |
2023-08-14 |
Not clear |
| Alon Doron, Yoav Piura, Ifat Vigiser, Hadar Kolb, Keren Regev, Nahum Nesher, Arnon Karn. BNT162b2 mRNA COVID-19 vaccine three-dose safety and risk of COVID-19 in patients with myasthenia gravis during the alpha, delta, and omicron waves. Journal of neurology. 2022-07-30. PMID:35907046. |
during the alpha and delta waves, covid-19 mortality and severe disease were significantly higher (26.7%) compared to the general population (0.96%). |
2022-07-30 |
2023-08-14 |
Not clear |