| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Rubio, J Aramburu, J Ontañón, M López-Botet, P Aparici. A novel functional cell surface dimer (kp43) serves as accessory molecule for the activation of a subset of human gamma delta T cells. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 3. 1993-08-26. PMID:8335929. |
kp43 is a cell surface molecule expressed by nk cells, gamma delta t lymphocytes, and a small subset of cd56+ alpha beta t cells. |
1993-08-26 |
2023-08-12 |
human |
| M Bellone, N Ostlie, P Karachunski, A A Manfredi, B M Conti-Troncon. Cryptic epitopes on the nicotinic acetylcholine receptor are recognized by autoreactive CD4+ cells. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 2. 1993-08-25. PMID:7687612. |
anti-tachr cd4+ cells did not cross-react with murine alpha subunit sequences, or with any synthetic sequence of human gamma and delta subunits, which are very similar to the corresponding murine subunits. |
1993-08-25 |
2023-08-12 |
mouse |
| M Bellone, N Ostlie, P Karachunski, A A Manfredi, B M Conti-Troncon. Cryptic epitopes on the nicotinic acetylcholine receptor are recognized by autoreactive CD4+ cells. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 2. 1993-08-25. PMID:7687612. |
in addition to the three immunodominant alpha subunit epitopes, other epitopes were recognized by cd4+ cells within the sequences t alpha 304-322, t gamma 105-124, t gamma 120-139, t gamma 401-420, t gamma 357-376, t delta 16-35, t delta 61-80, t delta 121-140, and t delta 301-320. |
1993-08-25 |
2023-08-12 |
mouse |
| M Bellone, N Ostlie, P Karachunski, A A Manfredi, B M Conti-Troncon. Cryptic epitopes on the nicotinic acetylcholine receptor are recognized by autoreactive CD4+ cells. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 2. 1993-08-25. PMID:7687612. |
cd4+ cells thus sensitized cross-reacted with the mammalian sequences alpha 304-322, gamma 105-124, gamma 120-139, and delta 301-320. |
1993-08-25 |
2023-08-12 |
mouse |
| M Bellone, N Ostlie, P Karachunski, A A Manfredi, B M Conti-Troncon. Cryptic epitopes on the nicotinic acetylcholine receptor are recognized by autoreactive CD4+ cells. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 2. 1993-08-25. PMID:7687612. |
we determined the dose dependence of the sensitization of cd4+ cells in vivo to the strongly immunodominant epitope peptide t alpha 150-169 and to the cryptic epitope peptides t gamma 120-139 and t delta 301-320 by immunizing mice with increasing doses of peptide (approximately 1.2 to approximately 20 nmol), and testing the in vitro anti-peptide response of the cd4+ cells. |
1993-08-25 |
2023-08-12 |
mouse |
| J Friedebold, B Bowie. Physiological and biochemical characterization of the soluble formate dehydrogenase, a molybdoenzyme from Alcaligenes eutrophus. Journal of bacteriology. vol 175. issue 15. 1993-08-25. PMID:8335630. |
the native enzyme exhibited an m(r) of 197,000 and a heterotetrameric quaternary structure with nonidentical subunits of m(r) 110,000 (alpha), 57,000 (beta), 19,400 (gamma), and 11,600 (delta). |
1993-08-25 |
2023-08-12 |
Not clear |
| A Neisig, A Vangsted, J Zeuthen, C Geisle. Assembly of the T-cell antigen receptor. Participation of the CD3 omega chain. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 2. 1993-08-25. PMID:8335916. |
the human tcr is composed of the ti alpha beta heterodimer in association with the cd3 chains cd3 gamma delta epsilon zeta 2. |
1993-08-25 |
2023-08-12 |
human |
| A Neisig, A Vangsted, J Zeuthen, C Geisle. Assembly of the T-cell antigen receptor. Participation of the CD3 omega chain. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 2. 1993-08-25. PMID:8335916. |
the results indicate that: 1) cd3 omega associates primarily with the cd3 delta epsilon complex; 2) cd3 omega is not associated with single ti alpha or ti beta chains, but is present in complexes composed of both the cd3 and the ti chains; 3) cd3 omega is part of the complete, intracellular receptor complex ti alpha beta/cd3 gamma epsilon delta omega zeta 2; and 4) cd3 omega dissociates from the ti/cd3 complex in the er before maturation of the ti alpha beta heterodimer. |
1993-08-25 |
2023-08-12 |
human |
| W N Green, T Claudi. Acetylcholine receptor assembly: subunit folding and oligomerization occur sequentially. Cell. vol 74. issue 1. 1993-08-20. PMID:8334706. |
alpha beta gamma delta tetramers are formed slowly by the addition of delta subunits to trimers, and finally a second alpha subunit is added to form alpha 2 beta gamma delta pentamers. |
1993-08-20 |
2023-08-12 |
Not clear |
| T P Molchanova, Y V Postnikov, L H Gu, T H Huisma. Hb A2-Grovetown or alpha 2 delta (2)75(E19)Leu-->Val. Hemoglobin. vol 17. issue 3. 1993-08-19. PMID:8330984. |
hb a2-grovetown or alpha 2 delta (2)75(e19)leu-->val. |
1993-08-19 |
2023-08-12 |
Not clear |
| J Thode, R B Holgersen, T Gerstenber. Variability of the calcium ion activity with pH in stone-forming and non-stone-forming urine. Scandinavian journal of clinical and laboratory investigation. Supplementum. vol 214. 1993-08-19. PMID:8332846. |
however the slope of the curves in the stone-formers and healthy adults changed from a median value of delta lg alpha ca2+/delta ph of -0.139 and -0.173 (ns) respectively, to a highly significant difference of -1.326 and -1.053 (p < 0.0001) between the groups, indicating increased binding/precipitation of ca2+ in stone-formers than in healthy adults supporting the theory of the lack of inhibitors in stone-formers. |
1993-08-19 |
2023-08-12 |
Not clear |
| H J Weiss, B Lage. Studies of thromboxane B2, platelet factor 4, and fibrinopeptide A in bleeding-time blood of patients deficient in von Willebrand factor, platelet glycoproteins Ib and IIb-IIIa, and storage granules. Blood. vol 82. issue 2. 1993-08-17. PMID:8329704. |
the blood volumes and concentrations of thromboxane b2 (txb2), platelet factor 4 (pf4), and fibrinopeptide a (fpa) were measured every 30 seconds in bleeding-time blood in normal subjects and in patients with idiopathic thrombocytopenic purpura (itp), delta and alpha delta storage pool deficiency (spd), bernard-soulier syndrome (bss), thrombasthenia (tsa), and von willebrand's disease (vwd). |
1993-08-17 |
2023-08-12 |
human |
| D R Witcher, M De Waard, J Sakamoto, C Franzini-Armstrong, M Pragnell, S D Kahl, K P Campbel. Subunit identification and reconstitution of the N-type Ca2+ channel complex purified from brain. Science (New York, N.Y.). vol 261. issue 5120. 1993-08-17. PMID:8392754. |
the channel consists of a 230-kilodalton subunit (alpha 1b) that is tightly associated with a 160-kilodalton subunit (alpha 2 delta), a 57-kilodalton subunit (beta 3), and a 95-kilodalton glycoprotein subunit. |
1993-08-17 |
2023-08-12 |
rabbit |
| M Oblatt-Montal, L K Bühler, T Iwamoto, J M Tomich, M Monta. Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. I. Transmembrane segment M2 of the nicotinic cholinergic receptor channel is a key pore-lining structure. The Journal of biological chemistry. vol 268. issue 20. 1993-08-12. PMID:7686900. |
peptides m2 delta and m2 alpha 4 with sequences of m2 from muscle-like torpedo californica achr delta subunit and from rat neuronal achr alpha 4 subunit form cation-selective channels in lipid bilayers with predominant single-channel conductances in 0.5 m kcl of 20 ps and 27 ps, respectively. |
1993-08-12 |
2023-08-12 |
rat |
| M Oblatt-Montal, L K Bühler, T Iwamoto, J M Tomich, M Monta. Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. I. Transmembrane segment M2 of the nicotinic cholinergic receptor channel is a key pore-lining structure. The Journal of biological chemistry. vol 268. issue 20. 1993-08-12. PMID:7686900. |
corresponding analogs with presumed pore-lining residues serine 8 or phenylalanine 16 specifically substituted by alanine retain the ability to self-assemble into conductive oligomers and form channels with primary conductances of 16 ps and 22 ps for m2 delta analogs and of 14 ps and 26 ps for m2 alpha 4 analogs. |
1993-08-12 |
2023-08-12 |
rat |
| M Oblatt-Montal, L K Bühler, T Iwamoto, J M Tomich, M Monta. Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. I. Transmembrane segment M2 of the nicotinic cholinergic receptor channel is a key pore-lining structure. The Journal of biological chemistry. vol 268. issue 20. 1993-08-12. PMID:7686900. |
four-helix bundle proteins t4m2 delta and t4m2 alpha 4 exhibit conductances in 0.5 m kcl of 20 ps and 26 ps. |
1993-08-12 |
2023-08-12 |
rat |
| M J Kaminski, P R Bergstresser, A Takashim. In vivo activation of mouse dendritic epidermal T cells in sites of contact dermatitis. European journal of immunology. vol 23. issue 7. 1993-08-09. PMID:8325341. |
il-2 responses were seen as early as 2 days after croton oil treatment and peaked between days 5 and 10. gamma delta tcr-bearing cells, most likely resident detc, were the major population to respond to il-2, since depletion of gamma delta tcr+ cells, but not alpha beta tcr+ cells, abolished that responsiveness, and since gamma delta tcr+ cell numbers increased markedly in the cultures that contained added il-2. |
1993-08-09 |
2023-08-12 |
mouse |
| C Schleussner, R Ceredi. Analysis of intraepithelial lymphocytes from major histocompatibility complex (MHC)-deficient mice: no evidence for a role of MHC class II antigens in the positive selection of V delta 4+ gamma delta T cells. European journal of immunology. vol 23. issue 7. 1993-08-09. PMID:8391987. |
by analyzing mice deficient mhc class ii antigens alone or in combination with mhc class i antigens, no evidence was found for positive selection of v delta 4+ cells among cd8 alpha + or cd4-cd8- subpopulations of gamma delta t cell receptor-positive cells. |
1993-08-09 |
2023-08-12 |
mouse |
| C Schleussner, R Ceredi. Analysis of intraepithelial lymphocytes from major histocompatibility complex (MHC)-deficient mice: no evidence for a role of MHC class II antigens in the positive selection of V delta 4+ gamma delta T cells. European journal of immunology. vol 23. issue 7. 1993-08-09. PMID:8391987. |
because v delta 4+, cd8 alpha + cells were reported to be positively selected on i-ek and hybrid i-ek/b molecules, class ii-deficient animals were crossed with i-ek transgenic mice and progeny examined for v delta 4 expression. |
1993-08-09 |
2023-08-12 |
mouse |
| C Czajkowski, C Kaufmann, A Karli. Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 13. 1993-08-06. PMID:8327511. |
we previously found that a 61-residue segment of the delta subunit contains aspartate or glutamate residues within 1 nm of cysteines in the acetylcholine binding site on the alpha subunit. |
1993-08-06 |
2023-08-12 |
mouse |