| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D K Mandal, L Bhattacharyya, S H Koenig, R D Brown, S Oscarson, C F Brewe. Studies of the binding specificity of concanavalin A. Nature of the extended binding site for asparagine-linked carbohydrates. Biochemistry. vol 33. issue 5. 1994-03-28. PMID:8110747. |
in the preceding paper [mandal, d. k., kishore, n., & brewer, c. f. (1994) biochemistry (preceding paper in this issue)] the trisaccharide 3,6-di-o-(alpha-d-mannopyranosyl)-d-mannose, which is present in all asparagine-linked carbohydrates, was shown by titration microcalorimetry to bind to the lectin concanavalin a (con a) with nearly -6 kcal mol-1 greater enthalpy change (delta h) than methyl alpha-d-mannopyranoside (me alpha man). |
1994-03-28 |
2023-08-12 |
Not clear |
| D K Mandal, L Bhattacharyya, S H Koenig, R D Brown, S Oscarson, C F Brewe. Studies of the binding specificity of concanavalin A. Nature of the extended binding site for asparagine-linked carbohydrates. Biochemistry. vol 33. issue 5. 1994-03-28. PMID:8110747. |
binding at the secondary site involves unfavorable interactions of the 2-equatorial hydroxyl of the alpha(1-3) glc derivative since this analog binds with 12-fold lower affinity and -3.4 kcal mol-1 lesser delta h than the trimannoside, whereas the alpha(1-3)-2-deoxyglc analog possesses essentially the same affinity and delta h as the trimannoside. |
1994-03-28 |
2023-08-12 |
Not clear |
| T Isobe, H S Lilleho. Dexamethasone suppresses T cell-mediated immunity and enhances disease susceptibility to Eimeria mivati infection. Veterinary immunology and immunopathology. vol 39. issue 4. 1994-03-28. PMID:8116219. |
flow cytometric analysis of lymphocyte composition revealed that the percentages of splenic lymphocytes bearing cd8 (cytotoxic-suppressor t cells), gamma delta t cell receptor (tcr 1), class ii major histocompatibility or surface igm antigens in dex-treated chickens were lower than in controls, whereas the percentages of t lymphocytes expressing cd3, cd4 (helper t cells) or alpha beta tcr antigens were significantly higher. |
1994-03-28 |
2023-08-12 |
Not clear |
| W Ma, P A Saunders, R Somogyi, M O Poulter, J L Barke. Ontogeny of GABAA receptor subunit mRNAs in rat spinal cord and dorsal root ganglia. The Journal of comparative neurology. vol 338. issue 3. 1994-03-25. PMID:7509352. |
the expression of mrnas encoding 13 gabaa receptor subunits (alpha 1-6, beta 1-3, gamma 1-3, and delta) in embryonic, postnatal, and adult rat spinal cord and dorsal root ganglia (drg) cells were studied by in situ hybridization and reverse transcription-polymerase chain reaction (rt-pcr) analysis. |
1994-03-25 |
2023-08-12 |
rat |
| W Ma, P A Saunders, R Somogyi, M O Poulter, J L Barke. Ontogeny of GABAA receptor subunit mRNAs in rat spinal cord and dorsal root ganglia. The Journal of comparative neurology. vol 338. issue 3. 1994-03-25. PMID:7509352. |
both techniques revealed the presence of all subunit mrnas originally found in the rat brain, except for alpha 6, which was not detectable, and delta, which was weakly detected only by rt-pcr. |
1994-03-25 |
2023-08-12 |
rat |
| W Ma, P A Saunders, R Somogyi, M O Poulter, J L Barke. Ontogeny of GABAA receptor subunit mRNAs in rat spinal cord and dorsal root ganglia. The Journal of comparative neurology. vol 338. issue 3. 1994-03-25. PMID:7509352. |
however, rt-pcr amplified minute amounts of mrnas for alpha 1, alpha 4, alpha 5, beta 1, beta 2, gamma 1, gamma 3, and delta subunits in adults, which were not found in film autoradiograms, but could be detected in a few grain-positive cells in emulsion-dipped sections. |
1994-03-25 |
2023-08-12 |
rat |
| R Levy-Toledano, L H Caro, D Accili, S I Taylo. Investigation of the mechanism of the dominant negative effect of mutations in the tyrosine kinase domain of the insulin receptor. The EMBO journal. vol 13. issue 4. 1994-03-25. PMID:8112298. |
despite the absence of alpha 2 beta beta mut hybrids, expression of the ile1153 mutant receptor inhibited the ability of the delta 43 truncated receptor to mediate insulin-stimulated phosphorylation of insulin receptor substrate-1 (irs-1). |
1994-03-25 |
2023-08-12 |
human |
| C S Yost, E Maestron. Clinical concentrations of edrophonium enhance desensitization of the nicotinic acetylcholine receptor. Anesthesia and analgesia. vol 78. issue 3. 1994-03-24. PMID:8109771. |
to investigate this possibility, we studied the effects of these drugs on the function of nachr (alpha 2 beta gamma delta subtype expressed in xenopus laevis oocytes) using a whole-cell voltage clamp technique. |
1994-03-24 |
2023-08-12 |
xenopus_laevis |
| D R Witcher, M De Waard, K P Campbel. Characterization of the purified N-type Ca2+ channel and the cation sensitivity of omega-conotoxin GVIA binding. Neuropharmacology. vol 32. issue 11. 1994-03-21. PMID:8107967. |
a functional n-type ca2+ channel (omega-conotoxin gvia receptor) has been purified from rabbit brain and shown to be composed of four subunits of molecular weights 230 k (alpha 1b), 160 k (alpha 2 delta), 95 k and 57 k (beta 3) [witcher d. r., de waard m., sakamoto j., franzini-armstrong c., pragnell m., kahl s.d. |
1994-03-21 |
2023-08-12 |
rabbit |
| Iu V Burov, A Ia Kapla. [The effect of amiridin on the spectral characteristics of the human EEG]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 5. 1994-03-21. PMID:8312813. |
eeg testing of 28 healthy males showed that amiridine (two tablets, each 20 mg, orally at a 45-min interval) significantly enhanced alpha stability and spectral power and decreased the stability of delta activity as compared to placebo. |
1994-03-21 |
2023-08-12 |
human |
| D E Macfarlane, L Manze. Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC beta-defective PET mutant. The Journal of biological chemistry. vol 269. issue 6. 1994-03-17. PMID:8308000. |
in comparison to s cells, we found that proliferating pet cells markedly underexpress mrna for pkc beta, but do express pkc alpha and pkc delta. |
1994-03-17 |
2023-08-12 |
human |
| J M Resnick, J C Manive. Immunohistochemical characterization of teratomatous and fetal neuroendocrine pancreas. Archives of pathology & laboratory medicine. vol 118. issue 2. 1994-03-17. PMID:8311655. |
increased proportions of alpha and delta cells were observed in three and five cases (relative to those of adult tissue), respectively, providing further evidence of immaturity. |
1994-03-17 |
2023-08-12 |
Not clear |
| C Genevée, V Chung, A Diu, T Hercend, F Triebe. TCR gene segments from at least one third of V alpha subfamilies rearrange at the delta locus. Molecular immunology. vol 31. issue 2. 1994-03-15. PMID:8309474. |
tcr gene segments from at least one third of v alpha subfamilies rearrange at the delta locus. |
1994-03-15 |
2023-08-12 |
human |
| C Genevée, V Chung, A Diu, T Hercend, F Triebe. TCR gene segments from at least one third of V alpha subfamilies rearrange at the delta locus. Molecular immunology. vol 31. issue 2. 1994-03-15. PMID:8309474. |
using pcr and an experimentally validated v alpha subfamily-specific oligonucleotide panel (v alpha 1-w29), we have investigated whether the tcr delta chain may increase its combinatorial diversity by using v genes considered as alpha chain-specific. |
1994-03-15 |
2023-08-12 |
human |
| C Genevée, V Chung, A Diu, T Hercend, F Triebe. TCR gene segments from at least one third of V alpha subfamilies rearrange at the delta locus. Molecular immunology. vol 31. issue 2. 1994-03-15. PMID:8309474. |
we show that at least 10 distinct human v alpha segments rearrange at the j delta locus, leading to scrambling of the two v gene repertoires. |
1994-03-15 |
2023-08-12 |
human |
| Y Liu, P Breh. Expression of subunit-omitted mouse nicotinic acetylcholine receptors in Xenopus laevis oocytes. The Journal of physiology. vol 470. 1994-03-14. PMID:7508504. |
to assess the contributions of receptors differing in subunit composition to the heterogeneity, various combinations of mouse alpha beta delta gamma epsilon subunit rnas were tested for the ability to express functional receptors in xenopus oocytes. |
1994-03-14 |
2023-08-12 |
mouse |
| Y Liu, P Breh. Expression of subunit-omitted mouse nicotinic acetylcholine receptors in Xenopus laevis oocytes. The Journal of physiology. vol 470. 1994-03-14. PMID:7508504. |
two combinations of dual-subunit rnas (alpha delta and alpha gamma) resulted in detectable ach-activated currents and six different combinations of three or more subunit rnas produced significant numbers of functional channels. |
1994-03-14 |
2023-08-12 |
mouse |
| Y Liu, P Breh. Expression of subunit-omitted mouse nicotinic acetylcholine receptors in Xenopus laevis oocytes. The Journal of physiology. vol 470. 1994-03-14. PMID:7508504. |
the order of combinations yielding the greatest amount of current was alpha beta gamma > alpha beta delta = alpha delta epsilon > alpha delta gamma > alpha delta > alpha gamma. |
1994-03-14 |
2023-08-12 |
mouse |
| Y Liu, P Breh. Expression of subunit-omitted mouse nicotinic acetylcholine receptors in Xenopus laevis oocytes. The Journal of physiology. vol 470. 1994-03-14. PMID:7508504. |
for alpha beta delta receptors the efficiency of expression was alpha: beta: delta (1/5:1/5:1) >> (1:1:1) >> (1/5:1:1/5) > (1:1/5:1/5). |
1994-03-14 |
2023-08-12 |
mouse |
| Y Liu, P Breh. Expression of subunit-omitted mouse nicotinic acetylcholine receptors in Xenopus laevis oocytes. The Journal of physiology. vol 470. 1994-03-14. PMID:7508504. |
when alpha delta or alpha gamma rna combinations were co-injected 2 days prior to the injection of beta rna, the expression was 2-5 times greater than when alpha beta injection was followed by injection of delta or gamma rna. |
1994-03-14 |
2023-08-12 |
mouse |