| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C T Morita, E M Beckman, J F Bukowski, Y Tanaka, H Band, B R Bloom, D E Golan, M B Brenne. Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells. Immunity. vol 3. issue 4. 1995-11-30. PMID:7584140. |
thus, in contrast with the presentation of conventional peptide antigens, protein antigens, and superantigens to alpha beta t cells, prenyl pyrophosphate antigens are presented to gamma delta t cells through a novel extracellular pathway that does not require antigen uptake, antigen processing, or mhc class i or class ii expression. |
1995-11-30 |
2023-08-12 |
human |
| V Gerzanich, X Peng, F Wang, G Wells, R Anand, S Fletcher, J Lindstro. Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors. Molecular pharmacology. vol 48. issue 4. 1995-11-29. PMID:7476906. |
in binding assays, epibatidine was used on achr subtypes immunoisolated from chicken brain and retina (alpha 4 beta 2, alpha 7, and alpha 8), the human neuronal cell line sh-sy5y (alpha 3 and alpha 7), torpedo electric organ (alpha 1 beta 1 gamma delta), or the human rhabdomyosarcoma cell line te671 (alpha 1 beta 1 gamma delta). |
1995-11-29 |
2023-08-12 |
human |
| F Wang, U P Naik, Y H Ehrlich, S Osada, S Ohno, E Korneck. Stimulatory antibody-induced activation and selective translocation of protein kinase C isoenzymes in human platelets. The Biochemical journal. vol 311 ( Pt 2). 1995-11-28. PMID:7487874. |
the translocation from the cytoplasm to the membrane induced by mab.f11 in pkc isoenzymes alpha and zeta was reversible, whereas translocation of the pkc isoenzymes delta, beta, eta' and theta was irreversible, with pkc levels remaining elevated in the membrane for at least 15 min. |
1995-11-28 |
2023-08-12 |
human |
| M Malissen, A Gillet, L Ardouin, G Bouvier, J Trucy, P Ferrier, E Vivier, B Malisse. Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene. The EMBO journal. vol 14. issue 19. 1995-11-28. PMID:7588594. |
finally, the absence of intact cd3-epsilon polypeptides had no discernible effect on the completion of tcr gamma and tcr delta gene rearrangements, emphasizing that they are probably not subjected to the same epigenetic controls as those operating on the expression of tcr alpha and beta genes. |
1995-11-28 |
2023-08-12 |
mouse |
| S J Simpson, E Mizoguchi, D Allen, A K Bhan, C Terhors. Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589135. |
colonic ctl were detectable prior to the appearance of disease in il-2null animals and ctl activity was confined to the tcr alpha beta, rather than to the tcr gamma delta iel subset. |
1995-11-28 |
2023-08-12 |
mouse |
| J Hartman, V Maassen, P Rieber, H Frick. T lymphocytes from normal human peritoneum are phenotypically different from their counterparts in peripheral blood and CD3- lymphocyte subsets contain mRNA for the recombination activating gene RAG-1. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589136. |
although the majority of peritoneal cavity lymphocyte (pcl) t cells expressed alpha beta t cell receptor (tcr), up to 17% expressed gamma delta tcr. |
1995-11-28 |
2023-08-12 |
human |
| J Kang, J Baker, D H Raule. Evidence that productive rearrangements of TCR gamma genes influence the commitment of progenitor cells to differentiate into alpha beta or gamma delta T cells. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589149. |
evidence that productive rearrangements of tcr gamma genes influence the commitment of progenitor cells to differentiate into alpha beta or gamma delta t cells. |
1995-11-28 |
2023-08-12 |
Not clear |
| J Kang, J Baker, D H Raule. Evidence that productive rearrangements of TCR gamma genes influence the commitment of progenitor cells to differentiate into alpha beta or gamma delta T cells. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589149. |
two models have been considered to account for the differentiation of gamma delta and alpha beta t cells from a common hematopoietic progenitor cell. |
1995-11-28 |
2023-08-12 |
Not clear |
| J Kang, J Baker, D H Raule. Evidence that productive rearrangements of TCR gamma genes influence the commitment of progenitor cells to differentiate into alpha beta or gamma delta T cells. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589149. |
in the other model, progenitor cells first undergo rearrangement of tcr gamma, delta, or both genes, and cells that succeed in generating a functional receptor commit to the gamma delta lineage, while those that do not proceed to attempt complete beta and subsequently alpha gene rearrangements. |
1995-11-28 |
2023-08-12 |
Not clear |
| T Yamada, Y Hitomi, M Satake, T Oikaw. Differential expression of the T cell receptor/CD3 genes and their lymphoid-specific transcription factor genes in murine T cell x fibroblast and T cell x B cell hybrids. European journal of immunology. vol 25. issue 9. 1995-11-28. PMID:7589150. |
marked differences were observed in the expression of the tcr alpha, cd3 delta, lef-1 and pebp2 alpha a genes in bel and sel hybrids. |
1995-11-28 |
2023-08-12 |
mouse |
| A M Mileo, E Palma, L Polenzani, C Limatola, F Grassi, F Euseb. Protein kinase C modulates exogenous acetylcholine current in Xenopus oocytes. Journal of neuroscience research. vol 41. issue 4. 1995-11-24. PMID:7473875. |
the modulation of acetylcholine-activated current (iach) by protein kinase c (pkc) was studied in xenopus laevis oocytes microinjected with either mrna extracted from c2c12 myotubes (c2c12 mrna) or rnas encoding murine alpha beta gamma delta subunits of the nicotinic ach receptor (nachr). |
1995-11-24 |
2023-08-12 |
rat |
| D Spaner, B L Cohen, R G Miller, R A Phillip. Antigen-presenting cells for naive transgenic gamma delta T cells. Potent activation by activated alpha beta T cells. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 8. 1995-11-22. PMID:7561093. |
in contrast, in vivo, only alpha beta t cells fully activated kn6+ gamma delta t cells as measured by an increase in the number of splenic kn6+ cells, the development of blast morphology, and the development of proliferative anergy in the responding kn6+ cells. |
1995-11-22 |
2023-08-12 |
mouse |
| D Spaner, B L Cohen, R G Miller, R A Phillip. Antigen-presenting cells for naive transgenic gamma delta T cells. Potent activation by activated alpha beta T cells. Journal of immunology (Baltimore, Md. : 1950). vol 155. issue 8. 1995-11-22. PMID:7561093. |
although the ags recognized by gamma delta t cells are generally unknown, ag presentation by activated alpha beta t cells may be an important method of activation. |
1995-11-22 |
2023-08-12 |
mouse |
| T Rowe, C Dezzutti, P C Guenthner, L Lam, T Hodge, M D Lairmore, R B Lal, T M Folk. Characterization of a HTLV-I-infected cell line derived from a patient with adult T-cell leukemia with stable co-expression of CD4 and CD8. Leukemia research. vol 19. issue 9. 1995-11-22. PMID:7564472. |
interestingly, phenotypically, the sp+ cell line is cd2+, cd3+ and coexpresses cd4 and cd8, yet lacks tcr alpha beta and tcr tau delta expression. |
1995-11-22 |
2023-08-12 |
human |
| L A Price, E M Kajkowski, J R Hadcock, B A Ozenberger, M H Pausc. Functional coupling of a mammalian somatostatin receptor to the yeast pheromone response pathway. Molecular and cellular biology. vol 15. issue 11. 1995-11-21. PMID:7565771. |
in sst2 delta cells, sstr2 functionally interacted with both a chimeric yeast/mammalian g alpha protein and the yeast g alpha protein, gpa1p; to promote growth. |
1995-11-21 |
2023-08-12 |
rat |
| O Duffy, F Berthou, L G Bardou, J F Méne. Effects of various cytochrome P-450 inducers on testosterone metabolism and several monooxygenase activities in Sprague-Dawley (SpD), high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats. Alcohol and alcoholism (Oxford, Oxfordshire). vol 30. issue 3. 1995-11-20. PMID:7545987. |
the formation of the metabolites of tst, hydroxylated on 2 alpha or 7 alpha or 16 alpha positions and oxidated on carbon 17 (delta 4), was found to be significantly increased in spd rats when compared with the has-las lines (p < 0.0001 in each case). |
1995-11-20 |
2023-08-12 |
rat |
| S M Naseem, J G Pace, R W Wannemache. A high-performance liquid chromatographic method for determining [3H]T-2 and its metabolites in biological fluids of the cynomolgus monkey. Journal of analytical toxicology. vol 19. issue 3. 1995-11-20. PMID:7564292. |
high-performance liquid chromatography (hplc) was used to separate, identify, and quantitate the trichothecin mycotoxin, t-2 (4 beta,15-diacetoxy-3 aopha-hydroxy-8 alpha [3-methyl-butyryloxy]-12,13-epoxy delta 9-trichothecin), and its metabolites in plasma and urine samples from cynomolgus monkeys treated with the toxin. |
1995-11-20 |
2023-08-12 |
monkey |
| M S Johnson, J Simpson, D J MacEwan, A Ison, R A Clegg, K Connor, R Mitchel. Phorbol ester and diacylglycerol activation of native protein kinase C species from various tissues. Molecular and cellular biochemistry. vol 146. issue 2. 1995-11-13. PMID:7565642. |
protein kinase c alpha, beta 1, delta, epsilon, and zeta/iota were all present in rat midbrain cytosolic extract, pkc alpha, beta 1, delta, and zeta/iota were present in spleen cytosol, and pkc alpha and zeta/iota were present in cos 7 cell cytosol. |
1995-11-13 |
2023-08-12 |
rat |
| L S Prichep, S C Kowalik, K Alper, C de Jesu. Quantitative EEG characteristics of children exposed in utero to cocaine. Clinical EEG (electroencephalography). vol 26. issue 3. 1995-11-09. PMID:7554304. |
these abnormalities were characterized by significant excess of relative power in the alpha frequency band, and deficits of absolute and relative power in the delta and theta bands. |
1995-11-09 |
2023-08-12 |
Not clear |
| M H Akabas, A Karli. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit. Biochemistry. vol 34. issue 39. 1995-11-08. PMID:7547996. |
the muscle-type acetylcholine (ach) receptor has the composition alpha 2 beta gamma delta. |
1995-11-08 |
2023-08-12 |
xenopus_laevis |