| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
immune or normal gamma delta t cells that assist alpha beta t cells in elicitation of contact sensitivity preferentially use v gamma 5 and v delta 4 variable region gene segments. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
in the current study, we confirmed previous findings suggesting that gamma delta t cells were involved in the successful adoptive cell transfer of contact sensitivity (cs) by alpha beta cs-effector t cells. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
in this study, we used hamster anti-mouse gamma delta-tcr mab treatment of cs-effector t cells, followed by enrichment and removal of the gamma delta t cells with goat anti-hamster ig-linked magnetic beads, or by addition of hemolytic rabbit c. this removal of gamma delta t cells abrogated adoptive cell transfers of cs, despite the presence of alpha beta t cells that are known to mediate cs. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
adoptive cell transfer of cs was reconstituted by adding back to the alpha beta cells, highly enriched gamma delta cells attached to anti-gamma delta-tcr magnetic beads. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
not only were gamma delta-enriched t cells from sensitized mice able to assist immune cs-effector alpha beta t cells, but gamma delta t cells from normal nonimmune mice also had cs-assisting activity, and furthermore, neither were mhc-restricted in this function. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
thus, cs-assisting gamma delta t cells were present endogenously in normal mice without prior immunization, and acted without ag specificity and without mhc restriction, to assist cs-effector alpha beta t cells. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
similar studies, with hamster mabs specific for v gamma and v delta portions of gamma delta-tcr, demonstrated that the gamma delta t cells that assisted the cs-effector alpha beta t cells preferentially expressed v gamma 5 and v delta 4 in their tcr. |
1996-02-27 |
2023-08-12 |
mouse |
| W Ptak, M Szczepanik, R Ramabhadran, P W Askenas. Immune or normal gamma delta T cells that assist alpha beta T cells in elicitation of contact sensitivity preferentially use V gamma 5 and V delta 4 variable region gene segments. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 3. 1996-02-27. PMID:8558025. |
in summary, these results demonstrated that v gamma 5+, v delta 4+, gamma delta t cells were needed to assist alpha beta effector t cells in the adoptive cell transfer of cs. |
1996-02-27 |
2023-08-12 |
mouse |
| J G Montoya, K E Lowe, C Clayberger, D Moody, D Do, J S Remington, S Talib, C S Subaust. Human CD4+ and CD8+ T lymphocytes are both cytotoxic to Toxoplasma gondii-infected cells. Infection and immunity. vol 64. issue 1. 1996-02-26. PMID:8557337. |
cytofluorometric analysis of these lines revealed > 99% cd3+, 85 to 95% cd3+ alpha beta t-cell-receptor-positive (tcr+), 5 to 9% cd3+ gamma delta tcr+, 50 to 70% cd4+, and 20 to 40% cd8+ cells when cells were examined during the first 3 weeks of stimulation and >99% cd3+, >99% cd3+ alpha beta tcr+, < 1% cd3+ gamma delta tcr+, 20 to 40% cd4+, and 60 to 80% cd8+ cells when cells were examined between 5 and 11 weeks. |
1996-02-26 |
2023-08-12 |
human |
| L A Guilloteau, A J Lax, S MacIntyre, T S Walli. The Salmonella dublin virulence plasmid does not modulate early T-cell responses in mice. Infection and immunity. vol 64. issue 1. 1996-02-26. PMID:8557343. |
over a period of 4 days postinfection, when both strains could be compared, similar changes in alpha beta and gamma delta t-cell subsets in peritoneal cavities, livers, and spleens were recorded, demonstrating no clear role of the virulence plasmid in modulation of early t-cell responses. |
1996-02-26 |
2023-08-12 |
mouse |
| J L Burton, M E Kehrl. Effects of dexamethasone on bovine circulating T lymphocyte populations. Journal of leukocyte biology. vol 59. issue 1. 1996-02-26. PMID:8558073. |
the cumulative results suggested that dexamethasone promoted gamma delta t cell migration out of peripheral blood via an l-selectin-independent mechanism and that dexamethasone did not alter alpha beta t cell migration kinetics. |
1996-02-26 |
2023-08-12 |
cattle |
| R Yang, C L. Developmental activity variations of DNA polymerase alpha, delta, epsilon in mouse forebrains and spleens. Science in China. Series B, Chemistry, life sciences & earth sciences. vol 38. issue 10. 1996-02-23. PMID:8554674. |
these results not only prove that dna polymerase alpha and delta take part in cell dna replication but also suggest that dna polymerase epsilon is involved in dna replication. |
1996-02-23 |
2023-08-12 |
mouse |
| Y H Chien, R Jore. Gamma delta T cells. T cells with B-cell-like recognition properties. Current biology : CB. vol 5. issue 10. 1996-02-22. PMID:8548281. |
recent results suggest there are fundamental differences in antigen recognition by alpha beta and gamma delta t-cell receptors, which might underlie possible differences in function between these two types of t cell. |
1996-02-22 |
2023-08-12 |
Not clear |
| F Boudreau, S Blais, C Asseli. Regulation of CCAAT/enhancer binding protein isoforms by serum and glucocorticoids in the rat intestinal epithelial crypt cell line IEC-6. Experimental cell research. vol 222. issue 1. 1996-02-22. PMID:8549649. |
whereas c/ebp alpha expression is not regulated by glucocorticoids, c/ebp beta and delta mrna and protein levels are rapidly induced. |
1996-02-22 |
2023-08-12 |
rat |
| F Boudreau, S Blais, C Asseli. Regulation of CCAAT/enhancer binding protein isoforms by serum and glucocorticoids in the rat intestinal epithelial crypt cell line IEC-6. Experimental cell research. vol 222. issue 1. 1996-02-22. PMID:8549649. |
moreover, c/ebp beta and delta containing dna binding complexes are increased by glucocorticoids as determined by supershift assays, in contrast to c/ebp alpha containing complexes. |
1996-02-22 |
2023-08-12 |
rat |
| G Moll, T Ubbink-Kok, H Hildeng-Hauge, J Nissen-Meyer, I F Nes, W N Konings, A J Driesse. Lactococcin G is a potassium ion-conducting, two-component bacteriocin. Journal of bacteriology. vol 178. issue 3. 1996-02-22. PMID:8550488. |
the combination of alpha and beta peptides (lactococcin g) dissipates the membrane potential (delta omega), and as a consequence cells release alpha-aminoisobutyrate, a non-metabolizable alanine analog that is accumulated through a proton motive-force dependent mechanism. |
1996-02-22 |
2023-08-12 |
Not clear |
| J Heider, X Mai, M W Adam. Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea. Journal of bacteriology. vol 178. issue 3. 1996-02-22. PMID:8550513. |
230,000, with subunit m(r) values of 47,000 (alpha), 34,000 (beta), 23,000 (gamma), and 13,000 (delta). |
1996-02-22 |
2023-08-12 |
Not clear |
| J Heider, X Mai, M W Adam. Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea. Journal of bacteriology. vol 178. issue 3. 1996-02-22. PMID:8550513. |
it contains about 11 iron and 12 acid-labile sulfide atoms and 13 cysteine residues per heterotetramer (alpha beta gamma delta), but thiamine pyrophosphate, which is required for catalytic activity, was lost during purification. |
1996-02-22 |
2023-08-12 |
Not clear |
| F Livak, D G Schat. T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells. Molecular and cellular biology. vol 16. issue 2. 1996-02-21. PMID:8552089. |
an additional 30 to 40% of the tcr alpha/delta locus exists as remarkably stable reciprocal products throughout t-cell development, with the consequence that the tcr c delta region is substantially retained in alpha beta committed t cells. |
1996-02-21 |
2023-08-12 |
Not clear |
| X Wu, J K Moore, J E Habe. Mechanism of MAT alpha donor preference during mating-type switching of Saccharomyces cerevisiae. Molecular and cellular biology. vol 16. issue 2. 1996-02-21. PMID:8552094. |
however, in mat alpha cells, hml is not an efficient donor when hmr is deleted; consequently, approximately one-third of ho hml alpha mat alpha hmr delta cells die because they fail to repair the ho endonuclease-induced double-strand break at mat. |
1996-02-21 |
2023-08-12 |
Not clear |