| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Johnson, E M Meiering, J E Wright, J Pardo, A Rosowsky, G Wagne. NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase. Biochemistry. vol 36. issue 15. 1997-05-12. PMID:9109647. |
the antitumor compound pt523 [n(alpha)-(4-amino-4-deoxypteroyl)-n(delta)-hemiphthaloyl-l- ornithine] was found to have an inhibition constant (k(i)) of 0.35 +/- 0.10 pm against human dihydrofolate reductase (hdhfr), 15-fold lower than that of the classical antifolate drug methotrexate (mtx). |
1997-05-12 |
2023-08-12 |
human |
| M G Thompson, S C Mackie, A Thom, R M Palme. Regulation of phospholipase D in L6 skeletal muscle myoblasts. Role of protein kinase c and relationship to protein synthesis. The Journal of biological chemistry. vol 272. issue 16. 1997-05-09. PMID:9099748. |
down-regulation removed both cytosolic (alpha) and membrane-bound (epsilon and delta) isoforms. |
1997-05-09 |
2023-08-12 |
Not clear |
| M J Longley, A J Pierce, P Modric. DNA polymerase delta is required for human mismatch repair in vitro. The Journal of biological chemistry. vol 272. issue 16. 1997-05-09. PMID:9099749. |
the highly enriched complementing activity copurified with a dna polymerase, and the most pure fraction contained dna polymerase delta but was free of detectable dna polymerases alpha and epsilon. |
1997-05-09 |
2023-08-12 |
human |
| C A La Porta, L Tessitore, R Comoll. Changes in protein kinase C alpha, delta and in nuclear beta isoform expression in tumour and lung metastatic nodules induced by diethylnitrosamine in the rat. Carcinogenesis. vol 18. issue 4. 1997-05-09. PMID:9111205. |
in this work we analysed the subcellular distribution and the in situ expression of classical pkc (alpha and beta) isoforms and the expression of pkc delta in the tumour and lung-metastases induced in the rat using the 'resistant hepatocyte' model of diethylnitrosamine-induced hepatocarcinogenesis. |
1997-05-09 |
2023-08-12 |
rat |
| C A La Porta, L Tessitore, R Comoll. Changes in protein kinase C alpha, delta and in nuclear beta isoform expression in tumour and lung metastatic nodules induced by diethylnitrosamine in the rat. Carcinogenesis. vol 18. issue 4. 1997-05-09. PMID:9111205. |
taken together, these results point to a different role for pkc alpha and delta in the development of tumour and metastatic nodules using the 'resistant hepatocyte' model of liver carcinogenesis, and suggest a possible involvement of nuclear pkc beta in the development of secondary tumours. |
1997-05-09 |
2023-08-12 |
rat |
| C Olive, D Nicol, M C Fal. Characterisation of gamma delta T cells in renal cell carcinoma patients by polymerase chain reaction analysis of T cell receptor transcripts. Cancer immunology, immunotherapy : CII. vol 44. issue 1. 1997-05-09. PMID:9111581. |
these til comprise predominantly alpha beta t cells, although gamma delta t cells are also present. |
1997-05-09 |
2023-08-12 |
human |
| N J Combates, P O Kwon, R W Rzepka, D Cohe. Involvement of the transcription factor NF-IL6 in phorbol ester induction of P-glycoprotein in U937 cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 8. issue 2. 1997-05-06. PMID:9040943. |
the majority of the dna-protein complex could be supershifted by an nf-il6 reactive antibody but not by antibodies for caat/enhancer binding protein alpha and delta, c-fos, or c-jun. |
1997-05-06 |
2023-08-12 |
human |
| R J Somsen, B J van't Klooster, M W van der Molen, H M van Leeuwen, R Lich. Growth spurts in brain maturation during middle childhood as indexed by EEG power spectra. Biological psychology. vol 44. issue 3. 1997-05-06. PMID:9043653. |
eeg power in the delta and theta frequency bands decreased gradually with age, while power in the alpha and beta bands changed very little. |
1997-05-06 |
2023-08-12 |
Not clear |
| R J Somsen, B J van't Klooster, M W van der Molen, H M van Leeuwen, R Lich. Growth spurts in brain maturation during middle childhood as indexed by EEG power spectra. Biological psychology. vol 44. issue 3. 1997-05-06. PMID:9043653. |
absolute power alpha only changed in the eldest children, but because of a substantial decrease in delta and theta with increasing age, the proportion of alpha relative to the other three bands increased. |
1997-05-06 |
2023-08-12 |
Not clear |
| F Setién Baranda, E Coto, J Menéndez Díaz, E Martínez-Naves, V Alvarez Martínez, C López-Larre. HLA class II and susceptibility and resistance to insulin-dependent diabetes mellitus in a population from the northwest of Spain. European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. vol 21. issue 4. 1997-05-05. PMID:9098435. |
by using the aetiologic fraction (delta) as an almost absolute measure of the strongest linkage of disequilibrium of a hla marker to the putative type i susceptibility locus, it has been found that the strength of association of the hla markers may be quantified as follows: dqa1*03-dqb1*0302 or dqa1*0501-dqb1*0201 > dr3 or dr4; presence of more than one dimer dq alpha beta of the six proposed by rønningen > non-asp57 dq beta and arg52 dq alpha > arg52 dq alpha > non-asp57 dq beta/non-asp57 dq beta > drb1*0301; dqa1*0501-dqb1*0201 > dqa1*03-dqb1*0302; dqb1*0302. |
1997-05-05 |
2023-08-12 |
Not clear |
| F Hervé, F Fouache, C Marché, J P Tillemen. Abnormal microheterogeneity detected in one commercial alpha 1-acid glycoprotein preparation using chromatography on immobilized metal affinity adsorbent and on hydroxyapatite. Journal of chromatography. B, Biomedical sciences and applications. vol 688. issue 1. 1997-05-02. PMID:9029311. |
the alpha and the sigma, beta, delta and gamma variants could correspond to altered forms of the a and the f1 and s variants, respectively, because of their similar retention behaviour on immobilized copper(ii) ions and their similar drug binding properties. |
1997-05-02 |
2023-08-12 |
human |
| E R Korpi, H Lüdden. Furosemide interactions with brain GABAA receptors. British journal of pharmacology. vol 120. issue 5. 1997-05-02. PMID:9138676. |
in recombinant gabaa receptors, furosemide antagonism of gaba-inhibition of [35s]-tbps binding depended only on the presence of alpha 6 and beta 2/3 subunits, irrespective of the presence or absence of gamma 2 or delta subunits. |
1997-05-02 |
2023-08-12 |
human |
| V U Dissanayake, N S Gee, J P Brown, G N Woodruf. Spermine modulation of specific [3H]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit. British journal of pharmacology. vol 120. issue 5. 1997-05-02. PMID:9138689. |
spermine modulation of specific [3h]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit. |
1997-05-02 |
2023-08-12 |
Not clear |
| V U Dissanayake, N S Gee, J P Brown, G N Woodruf. Spermine modulation of specific [3H]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit. British journal of pharmacology. vol 120. issue 5. 1997-05-02. PMID:9138689. |
recent studies have identified the [3h]-gabapentin-binding protein, purified from porcine cerebral cortical membranes, as the alpha 2 delta subunit of voltage-sensitive calcium channels (gee et al., 1996). |
1997-05-02 |
2023-08-12 |
Not clear |
| V U Dissanayake, N S Gee, J P Brown, G N Woodruf. Spermine modulation of specific [3H]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit. British journal of pharmacology. vol 120. issue 5. 1997-05-02. PMID:9138689. |
the findings that [3h]-gabapentin binding to the pure alpha 2 delta subunit was stimulated by spermine indicates that the alpha 2 delta subunit of voltage-sensitive calcium channels bears a modulatory spermine site. |
1997-05-02 |
2023-08-12 |
Not clear |
| V U Dissanayake, N S Gee, J P Brown, G N Woodruf. Spermine modulation of specific [3H]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit. British journal of pharmacology. vol 120. issue 5. 1997-05-02. PMID:9138689. |
thus the inhibitory spermine effect in membranes is also probably due to one or more modulatory sites on the alpha 2 delta subunit. |
1997-05-02 |
2023-08-12 |
Not clear |
| W B Pickworth, R V Fant, M F Butschky, J E Henningfiel. Effects of mecamylamine on spontaneous EEG and performance in smokers and non-smokers. Pharmacology, biochemistry, and behavior. vol 56. issue 2. 1997-05-01. PMID:9050073. |
in both groups, mecamylamine caused dose-related decreases in alpha frequency and increases in delta frequency; beta frequency was increased by the 5 and 10 mg doses. |
1997-05-01 |
2023-08-12 |
human |
| J Weber, A E Senio. Catalytic mechanism of F1-ATPase. Biochimica et biophysica acta. vol 1319. issue 1. 1997-05-01. PMID:9107315. |
subunits gamma, epsilon, b, and delta are at the interface between f1 and f0; gamma epsilon complex forms one element of the stalk, interacting with c at the base and alpha and beta at the top. |
1997-05-01 |
2023-08-12 |
Not clear |
| V J Knott, D Bakish, S Lusk, J Barkely, M Perugin. Quantitative EEG correlates of panic disorder. Psychiatry research. vol 68. issue 1. 1997-04-30. PMID:9027931. |
patients exhibited greater overall absolute power in the delta, theta, and alpha frequency bands and less relative power in the beta band. |
1997-04-30 |
2023-08-12 |
human |
| M J Diaz-Perez, I W Wainer, M Zannis-Hadjopoulos, G B Pric. Application of an in vitro system in the study of chemotherapeutic drug effects on DNA replication. Journal of cellular biochemistry. vol 61. issue 3. 1997-04-29. PMID:8761948. |
progesterone showed an increase in nucleotide incorporation (sensitive to bupdgtp inhibition of replication-specific polymerases alpha and delta) after preincubation with hela cell extracts, although progesterone receptors were not detectable in the hela cell extracts. |
1997-04-29 |
2023-08-12 |
Not clear |