| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Field, R J Oles, A S Lewis, S McCleary, J Hughes, L Sing. Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents. British journal of pharmacology. vol 121. issue 8. 1998-01-05. PMID:9283683. |
gabapentin (neurontin) is a novel antiepileptic agent that binds to the alpha 2 delta subunit of voltage-dependent calcium channels. |
1998-01-05 |
2023-08-12 |
rat |
| M Koike, A M Chumakov, S Takeuchi, T Tasaka, R Yang, T Nakamaki, N Tsuruoka, H P Koeffle. C/EBP-epsilon: chromosomal mapping and mutational analysis of the gene in leukemia and preleukemia. Leukemia research. vol 21. issue 9. 1998-01-02. PMID:9393598. |
we used a polymerase chain reaction (pcr)-based technique to examine dna from 93 hamster/human radiation hybrid clones in order chromosomally to map c/ebp-epsilon to 14q11.2 (between d14s264 and d14s275) which is telomeric to the t-cell receptor alpha and delta genes and centromeric to several other myeloid gene products including cathepsin g (ctsg) and chymase-1 (cma1). |
1998-01-02 |
2023-08-12 |
human |
| F Halary, M A Peyrat, E Champagne, M Lopez-Botet, A Moretta, L Moretta, H Vié, J J Fournié, M Bonnevill. Control of self-reactive cytotoxic T lymphocytes expressing gamma delta T cell receptors by natural killer inhibitory receptors. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394804. |
here we show that unlike alpha beta or v gamma 9- gamma delta t cells, the majority of v gamma 9v delta 2 t cells harbor natural killer inhibitory receptors (kir) (mainly cd94/nkg2a heterodimers), which are known to deliver inhibitory signals upon interaction with mhc class i molecules. |
1998-01-02 |
2023-08-12 |
human |
| K Inagaki-Ohara, H Nishimura, A Mitani, Y Yoshika. Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing gamma delta T cell receptor in mice. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394814. |
gamma delta i-iel constitutively expressed a high level of il-15 receptor alpha mrna and proliferated in response to il-15 more vigorously than alpha beta i-iel. |
1998-01-02 |
2023-08-12 |
mouse |
| F Livák, A Wilson, H R MacDonald, D G Schat. Alpha beta lineage-committed thymocytes can be rescued by the gamma delta T cell receptor (TCR) in the absence of TCR beta chain. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394823. |
alpha beta lineage-committed thymocytes can be rescued by the gamma delta t cell receptor (tcr) in the absence of tcr beta chain. |
1998-01-02 |
2023-08-12 |
mouse |
| F Livák, A Wilson, H R MacDonald, D G Schat. Alpha beta lineage-committed thymocytes can be rescued by the gamma delta T cell receptor (TCR) in the absence of TCR beta chain. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394823. |
commitment of the alpha beta and gamma delta t cell lineages within the thymus has been studied in t cell receptor (tcr)-transgenic and tcr mutant murine strains. |
1998-01-02 |
2023-08-12 |
mouse |
| F Livák, A Wilson, H R MacDonald, D G Schat. Alpha beta lineage-committed thymocytes can be rescued by the gamma delta T cell receptor (TCR) in the absence of TCR beta chain. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394823. |
we provide evidence that in the absence of functional tcr beta protein, the gamma delta tcr can promote the development of alpha beta-like thymocytes, which, however, do not expand significantly and do not mature into gamma delta t cells. |
1998-01-02 |
2023-08-12 |
mouse |
| F Livák, A Wilson, H R MacDonald, D G Schat. Alpha beta lineage-committed thymocytes can be rescued by the gamma delta T cell receptor (TCR) in the absence of TCR beta chain. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394823. |
these results show that commitment to the alpha beta lineage can be determined independently of the isotype of the tcr, and suggest that alpha beta versus gamma delta t cell lineage commitment is principally regulated by mechanisms distinct from tcr-mediated selection. |
1998-01-02 |
2023-08-12 |
mouse |
| F Livák, A Wilson, H R MacDonald, D G Schat. Alpha beta lineage-committed thymocytes can be rescued by the gamma delta T cell receptor (TCR) in the absence of TCR beta chain. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394823. |
to accommodate our data and those reported previously on the effect of tcr gamma and delta gene rearrangements on alpha beta t cell development, we propose a model in which lineage commitment occurs independently of tcr gene rearrangement. |
1998-01-02 |
2023-08-12 |
mouse |
| T Brabb, R Rubicz, V Mannikko, J Goverma. Separately expressed T cell receptor alpha and beta chain transgenes exert opposite effects on T cell differentiation and neoplastic transformation. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394835. |
in contrast, expression of the transgenic tcr beta chain causes immature t cells to accelerate differentiation into the alpha beta lineage and thus inhibits the generation of gamma delta cells. |
1998-01-02 |
2023-08-12 |
mouse |
| M Brenan, D J Ree. Sequence analysis of rat integrin alpha E1 and alpha E2 subunits: tissue expression reveals phenotypic similarities between intraepithelial lymphocytes and dendritic cells in lymph. European journal of immunology. vol 27. issue 11. 1998-01-02. PMID:9394838. |
immunofluorescence analysis revealed that mouse alpha e1 and rat alpha e2 are expressed in dendritic epidermal t cells in the skin, intraepithelial lymphocytes in the small intestine and in cells with a dendritic morphology present at sites where gamma delta t cells occur in lymphoid organs. |
1998-01-02 |
2023-08-12 |
mouse |
| M Nishikawa, T Hishinuma, K Nagata, Y Koseki, K Suzuki, M Mizugak. Effects of eicosapentaenoic acid (EPA) on prostacyclin production in diabetics: GC/MS analysis of PGI2 and PGI3 levels. Methods and findings in experimental and clinical pharmacology. vol 19. issue 6. 1997-12-19. PMID:9385592. |
the enzymatic metabolites, 6-keto-pgf1 alpha and delta 17-6-keto-pgf1 alpha, were measured by gas chromatography/high resolution-selected ion monitoring (gc/hr-sim) as markers of prostaglandin i2 (pgi2) and prostacyclin (pgi3) production in human sera. |
1997-12-19 |
2023-08-12 |
human |
| M Kudoh, S Takahashi, H Yonezaw. [Correlation between quantitative EEG and cerebral blood flow and oxygen metabolism in patients with dementia of Alzheimer type]. Rinsho shinkeigaku = Clinical neurology. vol 37. issue 5. 1997-12-16. PMID:9294320. |
to evaluate the relative changes in power for each frequency band between the two groups, the percentage power fraction (percentage power for each frequency band at site compared to the total power at that site; %delta for 2.0-3.8 hz, %theta for 4.0-7.8 hz, %alpha for 8.0-12.8 hz, %beta for 13.0-25.4 hz) was calculated. |
1997-12-16 |
2023-08-12 |
Not clear |
| M Kudoh, S Takahashi, H Yonezaw. [Correlation between quantitative EEG and cerebral blood flow and oxygen metabolism in patients with dementia of Alzheimer type]. Rinsho shinkeigaku = Clinical neurology. vol 37. issue 5. 1997-12-16. PMID:9294320. |
%delta at p3, p4 and t5 was significantly negatively correlated with rcbf in the corresponding regions, and %alpha at almost all the electrodes (except o1, f3, p3) was significantly positively correlated with rcbf in the corresponding regions. |
1997-12-16 |
2023-08-12 |
Not clear |
| M Kudoh, S Takahashi, H Yonezaw. [Correlation between quantitative EEG and cerebral blood flow and oxygen metabolism in patients with dementia of Alzheimer type]. Rinsho shinkeigaku = Clinical neurology. vol 37. issue 5. 1997-12-16. PMID:9294320. |
%delta and %alpha did not show any significant correlation with rcmro2. |
1997-12-16 |
2023-08-12 |
Not clear |
| G D'Urso, P Nurs. Schizosaccharomyces pombe cdc20+ encodes DNA polymerase epsilon and is required for chromosomal replication but not for the S phase checkpoint. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 23. 1997-12-16. PMID:9356477. |
in fission yeast both dna polymerase alpha (pol alpha) and delta (pol delta) are required for dna chromosomal replication. |
1997-12-16 |
2023-08-12 |
Not clear |
| R E Beattie, S G Volsen, D Smith, A L McCormack, S E Gillard, J P Burnett, S B Ellis, A Gillespie, M M Harpold, W Smit. Preparation and purification of antibodies specific to human neuronal voltage-dependent calcium channel subunits. Brain research. Brain research protocols. vol 1. issue 3. 1997-12-16. PMID:9385070. |
neuronal voltage-dependent calcium channels (vdccs) each comprising of alpha 1, alpha 2 delta, and beta subunits, are one mechanism by which excitable cells regulate the flux of calcium ions across the cell membrane following depolarisation studies have shown the expression of several alpha 1 and beta subtypes within neuronal tissue. |
1997-12-16 |
2023-08-12 |
human |
| R E Beattie, S G Volsen, D Smith, A L McCormack, S E Gillard, J P Burnett, S B Ellis, A Gillespie, M M Harpold, W Smit. Preparation and purification of antibodies specific to human neuronal voltage-dependent calcium channel subunits. Brain research. Brain research protocols. vol 1. issue 3. 1997-12-16. PMID:9385070. |
the resultant antibodies are analysed for specificity against the fusion proteins by elisa, and by immunofluorescence and western immunoblot analysis of recombinant hek293 cells stably transfected with cdnas encoding alpha 1, alpha 2 delta and beta subunits. |
1997-12-16 |
2023-08-12 |
human |
| S L Clarke, C E Robinson, J M Gimbl. CAAT/enhancer binding proteins directly modulate transcription from the peroxisome proliferator-activated receptor gamma 2 promoter. Biochemical and biophysical research communications. vol 240. issue 1. 1997-12-15. PMID:9367890. |
both c/ ebp alpha and c/ebp delta expression vectors activated transcription from a ppar gamma 2 promoter/luciferase expression vector by 5-6 fold in umr106 cells. |
1997-12-15 |
2023-08-12 |
Not clear |
| S L Clarke, C E Robinson, J M Gimbl. CAAT/enhancer binding proteins directly modulate transcription from the peroxisome proliferator-activated receptor gamma 2 promoter. Biochemical and biophysical research communications. vol 240. issue 1. 1997-12-15. PMID:9367890. |
mutation of the two c/ebp dna recognition elements at -340 bp and -327 bp within the ppar gamma 2 promoter reduced the inductive effects of both c/ebp alpha and c/ebp delta. |
1997-12-15 |
2023-08-12 |
Not clear |