| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacob H Nichols, Evan P Williams, Jyothi Parvathareddy, Xueyuan Cao, Ying Kong, Elizabeth Fitzpatrick, Richard J Webby, Colleen B Jonsso. Upper Respiratory Infection Drives Clinical Signs and Inflammatory Responses Following Heterologous Challenge of SARS-CoV-2 Variants of Concern in K18 Mice. Viruses. vol 15. issue 4. 2023-04-28. PMID:37112926. |
while nab titers against each virus were similar across all cohorts prior to challenge, the mice challenged with alpha and delta showed weight loss and upregulation of proinflammatory cytokines in the urt and lower rt (lrt). |
2023-04-28 |
2023-08-14 |
mouse |
| Jacob H Nichols, Evan P Williams, Jyothi Parvathareddy, Xueyuan Cao, Ying Kong, Elizabeth Fitzpatrick, Richard J Webby, Colleen B Jonsso. Upper Respiratory Infection Drives Clinical Signs and Inflammatory Responses Following Heterologous Challenge of SARS-CoV-2 Variants of Concern in K18 Mice. Viruses. vol 15. issue 4. 2023-04-28. PMID:37112926. |
we noted increased levels of viral rna transcripts only in the urt of mice challenged with alpha and delta. |
2023-04-28 |
2023-08-14 |
mouse |
| Jacob H Nichols, Evan P Williams, Jyothi Parvathareddy, Xueyuan Cao, Ying Kong, Elizabeth Fitzpatrick, Richard J Webby, Colleen B Jonsso. Upper Respiratory Infection Drives Clinical Signs and Inflammatory Responses Following Heterologous Challenge of SARS-CoV-2 Variants of Concern in K18 Mice. Viruses. vol 15. issue 4. 2023-04-28. PMID:37112926. |
in conclusion, our results suggested self-limiting breakthrough infections of alpha or delta in the urt, which correlated with clinical signs and a significant inflammatory response in mice. |
2023-04-28 |
2023-08-14 |
mouse |
| Fiona Senchyna, Rahul Sing. Dynamic Epidemiological Networks: A Data Representation Framework for Modeling and Tracking of SARS-CoV-2 Variants. Journal of computational biology : a journal of computational molecular cell biology. vol 30. issue 4. 2023-04-25. PMID:37098217. |
the results demonstrate how this framework could be used to provide a multiscale representation of the data by capturing molecular relationships between samples as well as those between variants, automatically identifying the emergence of high frequency variants (lineages), including variants of concern such as alpha and delta, and tracking their growth. |
2023-04-25 |
2023-08-14 |
human |
| Jillian T Teo, Stuart J Johnstone, Susan J Thoma. Use of portable devices to measure brain and heart activity during relaxation and comparative conditions: Electroencephalogram, heart rate variability, and correlations with self-report psychological measures. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 2023-04-24. PMID:37094613. |
psychophysiological indications of relaxation included higher hrv during relaxation, and higher delta, theta, and alpha power during the td condition. |
2023-04-24 |
2023-08-14 |
human |
| Daniel M Sakai, H Nicole Trenholme, Frederick J Torpy, Hannah A Craig, Rachel A Ree. Evaluation of the electroencephalogram in awake, sedated, and anesthetized dogs. Research in veterinary science. vol 159. 2023-04-23. PMID:37087922. |
interpretation of the eeg is facilitated by measuring the patient state index (psi), visual inspection of density spectral arrays (dsa), and power density analysis of the delta (0.1-4 hz), theta (4-8 hz), alpha (8-12 hz), and beta plus gamma (12-40 hz) frequency bands. |
2023-04-23 |
2023-08-14 |
Not clear |
| Alex M Mawla, Talitha van der Meulen, Mark O Huisin. Chromatin accessibility differences between alpha, beta, and delta cells identifies common and cell type-specific enhancers. BMC genomics. vol 24. issue 1. 2023-04-18. PMID:37069576. |
high throughput sequencing has enabled the interrogation of the transcriptomic landscape of glucagon-secreting alpha cells, insulin-secreting beta cells, and somatostatin-secreting delta cells. |
2023-04-18 |
2023-08-14 |
Not clear |
| Alex M Mawla, Talitha van der Meulen, Mark O Huisin. Chromatin accessibility differences between alpha, beta, and delta cells identifies common and cell type-specific enhancers. BMC genomics. vol 24. issue 1. 2023-04-18. PMID:37069576. |
all three endocrine cell types derive from a common pancreatic progenitor, yet alpha and beta cells have partially opposing functions, and delta cells modulate and control insulin and glucagon release. |
2023-04-18 |
2023-08-14 |
Not clear |
| Tim Larsen, Matthew L Bosworth, Daniel Ayoubkhani, Ryan Schofield, Raghib Ali, Kamlesh Khunti, Ann Sarah Walker, Myer Glickman, Camille Harrison, Vahé Nafilya. Inequalities in SARS-CoV-2 case rates by ethnicity, religion, measures of socioeconomic position, English proficiency, and self-reported disability: cohort study of 39 million people in England during the alpha and delta waves. BMJ medicine. vol 2. issue 1. 2023-04-17. PMID:37063237. |
inequalities in sars-cov-2 case rates by ethnicity, religion, measures of socioeconomic position, english proficiency, and self-reported disability: cohort study of 39 million people in england during the alpha and delta waves. |
2023-04-17 |
2023-08-14 |
Not clear |
| Tim Larsen, Matthew L Bosworth, Daniel Ayoubkhani, Ryan Schofield, Raghib Ali, Kamlesh Khunti, Ann Sarah Walker, Myer Glickman, Camille Harrison, Vahé Nafilya. Inequalities in SARS-CoV-2 case rates by ethnicity, religion, measures of socioeconomic position, English proficiency, and self-reported disability: cohort study of 39 million people in England during the alpha and delta waves. BMJ medicine. vol 2. issue 1. 2023-04-17. PMID:37063237. |
to examine sociodemographic inequalities in people with sars-cov-2 during the second (alpha) and third (delta) waves of the covid-19 pandemic. |
2023-04-17 |
2023-08-14 |
Not clear |
| Devika Subramanian, Aadith Vittala, Xinpu Chen, Christopher Julien, Sebastian Acosta, Craig Rusin, Carl Allen, Nicholas Rider, Zbigniew Starosolski, Ananth Annapragada, Sridevi Devara. Stratification of Pediatric COVID-19 cases by inflammatory biomarker profiling and machine learning. medRxiv : the preprint server for health sciences. 2023-04-17. PMID:37066407. |
group 3 consisted of 30 covid-19 and 32 mis-c patients seen between august-october 2021 infected with alpha and/or delta variants. |
2023-04-17 |
2023-08-14 |
Not clear |
| Vadim Axelrod, Camille Rozier, Elisa Sohier, Katia Lehongre, Claude Adam, Virginie Lambrecq, Vincent Navarro, Lionel Naccach. Intracranial study in humans: Neural spectral changes during watching comedy movie of Charlie Chaplin. Neuropsychologia. 2023-04-15. PMID:37061128. |
the most funny compared to least funny parts of the movie were associated with activity modulation in the broadband high-gamma (70-170 hz; mostly activation) and to a lesser extent gamma band (40-69hz; activation) and low frequencies (1-12 hz, delta, theta, alpha bands; mostly deactivation). |
2023-04-15 |
2023-08-14 |
human |
| Milena Aleksova, Yana Todorova, Radoslava Emilova, Magdalena Baymakova, Nina Yancheva, Radina Andonova, Anelia Zasheva, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Maria Nikolov. Virus-Specific Stem Cell Memory CD8+ T Cells May Indicate a Long-Term Protection against Evolving SARS-CoV-2. Diagnostics (Basel, Switzerland). vol 13. issue 7. 2023-04-13. PMID:37046496. |
included were 107 samples from 95 donors infected during the periods 03/2020-07/2021 and 09/2021-03/2022, coinciding with the prevalence of b.1.1.7 (alpha) and b.1.617.2 (delta) variants in bulgaria. |
2023-04-13 |
2023-08-14 |
Not clear |
| Ioanna Ioannou, Angeliki Chatziantoniou, Constantinos Drenios, Panayiota Christodoulou, Malamati Kourti, Apostolos Zaravino. Signatures of Co-Deregulated Genes and Their Transcriptional Regulators in Kidney Cancers. International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047552. |
differential expression and upstream regulators, including transcription factors [myc proto-oncogene (myc), ccaat enhancer binding protein delta (cebpd), rela proto-oncogene, nf-kb subunit (rela), zinc finger miz-type containing 1 (zmiz1), negative elongation factor complex member e (nelfe) and kruppel-like factor 4 (klf4)] and protein kinases [casein kinase 2 alpha 1 (csnk2a1), mitogen-activated protein kinases 1 (mapk1) and 14 (mapk14), sirtuin 1 (sirt1), cyclin dependent kinases 1 (cdk1) and 4 (cdk4), homeodomain interacting protein kinase 2 (hipk2) and extracellular signal-regulated kinases 1 and 2 (erk1/2)], were computed using the characteristic direction, as well as geo2enrichr and x2k, respectively, and further subjected to go and kegg pathways enrichment analyses. |
2023-04-13 |
2023-08-14 |
Not clear |
| Małgorzata Pawłowska, Maria Pokorska-Śpiewak, Ewa Talarek, Anna Mania, Barbara Hasiec, Elżbieta Żwirek-Pytka, Magdalena Stankiewicz, Martyna Stani, Paulina Frańczak-Chmura, Leszek Szenborn, Izabela Zaleska, Joanna Chruszcz, Ewa Majda-Stanisławska, Urszula Dryja, Kamila Gąsiorowska, Magdalena Figlerowicz, Katarzyna Mazur-Melewska, Kamil Faltin, Przemysław Ciechanowski, Michał Peregrym, Joanna Łasecka-Zadrożna, Józef Rudnicki, Barbara Szczepańska, Ilona Pałyga-Bysiecka, Ewelina Rogowska, Dagmara Hudobska-Nawrot, Katarzyna Domańska-Granek, Adam Sybilski, Izabela Kucharek, Justyna Franczak, Małgorzata Sobolewska-Pilarczyk, Ernest Kuchar, Michał Wronowski, Maria Paryż, Bolesław Kalicki, Kacper Toczyłowski, Artur Sulik, Sławomira Niedźwiecka, Robert Flisiak, Magdalena Marczyńsk. Clinical Course and Severity of COVID-19 in 940 Infants with and without Comorbidities Hospitalized in 2020 and 2021: The Results of the National Multicenter Database SARSTer-PED. Journal of clinical medicine. vol 12. issue 7. 2023-04-13. PMID:37048562. |
this study aimed to analyze the differences in severity and clinical characteristics of covid-19 in infants hospitalized in poland in 2021, when the dominance of variants of concern (vocs) alpha and delta was reported, compared to 2020, when original (wild) sars-cov-2 was dominant (iii-iv vs. i-ii waves of the pandemic, respectively). |
2023-04-13 |
2023-08-14 |
Not clear |
| Aysegul Bostanci, Umut Gazi, Ozgur Tosun, Kaya Suer, Emine Unal Evren, Hakan Evren, Tamer Sanlida. Long-COVID-19 in Asymptomatic, Non-Hospitalized, and Hospitalized Populations: A Cross-Sectional Study. Journal of clinical medicine. vol 12. issue 7. 2023-04-13. PMID:37048697. |
b.1.617.2 (delta) (41.9%) was the most common sars-cov-2 variant responsible for the infections, followed by ba.1 (omicron) (34.8%), b.1.1.7 (alpha) (15.5%), and wild-type sars-cov-2 (7.8%). |
2023-04-13 |
2023-08-14 |
human |
| Maria Pokorska-Śpiewak, Ewa Talarek, Małgorzata Pawłowska, Anna Mania, Barbara Hasiec, Elżbieta Żwirek-Pytka, Magdalena Stankiewicz, Martyna Stani, Paulina Frańczak-Chmura, Leszek Szenborn, Izabela Zaleska, Joanna Chruszcz, Ewa Majda-Stanisławska, Urszula Dryja, Kamila Gąsiorowska, Magdalena Figlerowicz, Katarzyna Mazur-Melewska, Kamil Faltin, Przemysław Ciechanowski, Michał Peregrym, Joanna Łasecka-Zadrożna, Józef Rudnicki, Barbara Szczepańska, Ilona Pałyga-Bysiecka, Ewelina Rogowska, Dagmara Hudobska-Nawrot, Katarzyna Domańska-Granek, Adam Sybilski, Izabela Kucharek, Justyna Franczak, Małgorzata Sobolewska-Pilarczyk, Ernest Kuchar, Michał Wronowski, Maria Paryż, Bolesław Kalicki, Kacper Toczyłowski, Artur Sulik, Sławomira Niedźwiecka, Anna Gorczyca, Magdalena Marczyńsk. The Influence of SARS-CoV-2 Variants B.1.1.7 and B.1.617.2 on a Different Clinical Course and Severity of COVID-19 in Children Hospitalized in 2021 Compared With 2020. The Pediatric infectious disease journal. 2023-04-13. PMID:37053572. |
this study aimed to analyze the differences in the epidemiologic and clinical characteristics of coronavirus disease 2019 (covid-19) in children hospitalized in 2021, when the severe acute respiratory syndrome coronavirus 2 variants b.1.1.7 (alpha) and b.1.617.2 (delta) dominated, compared with 2020. |
2023-04-13 |
2023-08-14 |
Not clear |
| b' Lorna Stemberger Mari\\xc4\\x87, Vladimir Trkulja, Davor Petrovi\\xc4\\x87, Kristina Lah Tomuli\\xc4\\x87, Ines Bartulovi\\xc4\\x87, Goran Te\\xc5\\xa1ovi\\xc4\\x8. Incidence and Clinical Phenotype of Multisystem Inflammatory Syndrome in Children After Two SARS-CoV-2 Pandemic Waves: A Croatian Prospective Nationwide Study. The Pediatric infectious disease journal. 2023-04-13. PMID:37054396.' |
the severe acute respiratory syndrome coronavirus 2 virus alpha strain appeared associated with a higher propensity to result in multisystem inflammatory syndrome in children than the delta strain but did not appear related to disease severity. |
2023-04-13 |
2023-08-14 |
Not clear |
| Jessica Laird-Gion, Audrey Dionne, Kimberlee Gauvreau, Annette Baker, Megan Day-Lewis, Sarah de Ferranti, Kevin Friedman, Numaira Khan, Simran Mahanta, Mary Beth Son, Francesca Sperotto, Jane W Newburge. MIS-C across three SARS-CoV-2 variants: Changes in COVID-19 testing and clinical characteristics in a cohort of U.S. children. European journal of pediatrics. 2023-04-13. PMID:37055630. |
patients were sorted into alpha, delta, and omicron variant cohorts by date of admission and using national and regional data on variant prevalence. among 108 patients with mis-c, significantly more patients had a documented history of covid-19 in the two months before mis-c during omicron (74%) than during alpha (42%) (p = 0.03). |
2023-04-13 |
2023-08-14 |
Not clear |
| Jessica Laird-Gion, Audrey Dionne, Kimberlee Gauvreau, Annette Baker, Megan Day-Lewis, Sarah de Ferranti, Kevin Friedman, Numaira Khan, Simran Mahanta, Mary Beth Son, Francesca Sperotto, Jane W Newburge. MIS-C across three SARS-CoV-2 variants: Changes in COVID-19 testing and clinical characteristics in a cohort of U.S. children. European journal of pediatrics. 2023-04-13. PMID:37055630. |
this study is limited by its small, single-center case series design and by classification of patients into era of variant by admission date rather than genomic testing of sars- cov-2 samples. conclusion: antecedent covid-19 was more often documented in the omicron than alpha or delta eras, but clinical severity of mis-c was similar across variant eras. |
2023-04-13 |
2023-08-14 |
Not clear |