| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rima Elhage, Pierre Gourdy, Laurent Brouchet, Jacek Jawien, Marie-José Fouque, Catherine Fiévet, Xavier Huc, Yara Barreira, Jean Claude Couloumiers, Jean-François Arnal, Francis Bayar. Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice. The American journal of pathology. vol 165. issue 6. 2005-01-11. PMID:15579444. |
whereas tcr gamma delta(+) t lymphocytes appeared to play a modest role, tcr alpha beta(+) t lymphocytes played a major role as their deficiency significantly prevented early and late atherosclerosis at all arterial sites. |
2005-01-11 |
2023-08-12 |
mouse |
| Xupei Huang, Jeffery W Walke. Myofilament anchoring of protein kinase C-epsilon in cardiac myocytes. Journal of cell science. vol 117. issue Pt 10. 2005-01-04. PMID:15039458. |
the delta isoform of pkc (delta-pkc) did not bind to cardiac myofibrils regardless of the activator used, and the alpha isoform (alpha-pkc) bound only under strong activating conditions. |
2005-01-04 |
2023-08-12 |
Not clear |
| H Iwakum. Electroencephalographical effects of sarpogrelate hydrochloride versus ticlopidine hydrochloride in elderly patients with peripheral atherosclerosis. The Journal of international medical research. vol 32. issue 3. 2004-12-28. PMID:15174221. |
in the posterior area, sarpogrelate significantly decreased the %slow and increased the %alpha values, and was associated with a significantly higher delta alpha value than ticlopidine. |
2004-12-28 |
2023-08-12 |
Not clear |
| Francesco Forconi, Surinder S Sahota, Donatella Raspadori, Micaela Ippoliti, Gavin Babbage, Francesco Lauria, Freda K Stevenso. Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch. Blood. vol 104. issue 10. 2004-12-23. PMID:15284115. |
multiple tumor-derived variable-(diversity)-joining-constant mu delta, gamma, alpha (v(d)j-cmu, delta, gamma, alpha) transcripts were confirmed in single cells of a further case. |
2004-12-23 |
2023-08-12 |
Not clear |
| Nadia Rucci, Enrico Ricevuto, Corrado Ficorella, Maurizio Longo, Marie Perez, Claudia Di Giacinto, Alessia Funari, Anna Teti, Silvia Migliacci. In vivo bone metastases, osteoclastogenic ability, and phenotypic characterization of human breast cancer cells. Bone. vol 34. issue 4. 2004-12-22. PMID:15050901. |
mcf-7adr also showed significantly higher levels of the protein kinase c (pkc) alpha and beta2 and a selective activation of pkc compared to mcf-7, where the most abundant isoforms were beta1 and delta. |
2004-12-22 |
2023-08-12 |
mouse |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
synthesis and biological evaluation of 6-aryl-6h-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. |
2004-12-22 |
2023-08-12 |
Not clear |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
a novel class of 2h-pyrrolo[3,4-c]pyridazine ligands of the alpha (2) delta subunit of voltage-gated calcium channels is described. |
2004-12-22 |
2023-08-12 |
Not clear |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
compound 4a with high affinity toward alpha (2) delta was identified through structure-activity relationship studies of the lead compound. |
2004-12-22 |
2023-08-12 |
Not clear |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
tritiated ligand [(3)h]-4b was synthesized to demonstrate that this ligand binds to the same site as gabapentin toward alpha (2) delta subunit of voltage-gated calcium channels. |
2004-12-22 |
2023-08-12 |
Not clear |
| J B Dahl, O Mathiesen, S Møinich. 'Protective premedication': an option with gabapentin and related drugs? A review of gabapentin and pregabalin in in the treatment of post-operative pain. Acta anaesthesiologica Scandinavica. vol 48. issue 9. 2004-12-22. PMID:15352959. |
gabapentin, which binds to the alpha(2)delta subunit of the voltage-dependent calcium channel, is active in animal models of 'pathological' but not in models of 'physiological' pain. |
2004-12-22 |
2023-08-12 |
Not clear |
| Marsha R Haynes, Gillian E W. Evolution of the variable gene segments and recombination signal sequences of the human T-cell receptor alpha/delta locus. Immunogenetics. vol 56. issue 7. 2004-12-21. PMID:15378298. |
the t-cell receptor (tcr) alpha and delta loci are particularly interesting because of their unique genomic structure, in that the gene segments for each locus are interspersed. |
2004-12-21 |
2023-08-12 |
human |
| Marsha R Haynes, Gillian E W. Evolution of the variable gene segments and recombination signal sequences of the human T-cell receptor alpha/delta locus. Immunogenetics. vol 56. issue 7. 2004-12-21. PMID:15378298. |
our phylogenetic analyses divided the alpha and delta variable gene segments into two major groups each with distinguishing motifs in both the framework and complementarity determining regions (cdrs). |
2004-12-21 |
2023-08-12 |
human |
| Lynnette Phillips McCluske. Up-regulation of activated macrophages in response to degeneration in the taste system: effects of dietary sodium restriction. The Journal of comparative neurology. vol 479. issue 1. 2004-12-21. PMID:15389612. |
at day 1, 2, 5, 7, or 50 postsectioning, immunostaining was used to detect the percentage of staining for activated macrophages, the number of alpha beta t cells, and the number of delta gamma epithelial t cells in the tongue. |
2004-12-21 |
2023-08-12 |
rat |
| Xavier López, Josep M Poble. DFT study on the five isomers of PW(12)O(40)(3)(-): relative stabilization upon reduction. Inorganic chemistry. vol 43. issue 22. 2004-12-16. PMID:15500315. |
the energy scale fits the experimental findings as well as the number of rotated triads of the metal-oxide core since the energy grows as follows: alpha < beta < gamma < delta < epsilon. |
2004-12-16 |
2023-08-12 |
Not clear |
| Xavier López, Josep M Poble. DFT study on the five isomers of PW(12)O(40)(3)(-): relative stabilization upon reduction. Inorganic chemistry. vol 43. issue 22. 2004-12-16. PMID:15500315. |
the other isomers, delta and epsilon, are much more unstable than alpha or beta in any reduction state. |
2004-12-16 |
2023-08-12 |
Not clear |
| M Rihl, J Gu, D Baeten, E Märker-Hermann, J C Goodall, J S H Gaston, J G Kuipers, H Zeidler, D T Y Y. Alpha beta but not gamma delta T cell clones in synovial fluids of patients with reactive arthritis show active transcription of tumour necrosis factor alpha and interferon gamma. Annals of the rheumatic diseases. vol 63. issue 12. 2004-12-16. PMID:15547094. |
alpha beta but not gamma delta t cell clones in synovial fluids of patients with reactive arthritis show active transcription of tumour necrosis factor alpha and interferon gamma. |
2004-12-16 |
2023-08-12 |
Not clear |
| P W Hoban, M Heydarian, W A Beckham, A H Beddo. Dose rate dependence of a PTW diamond detector in the dosimetry of a 6 MV photon beam. Physics in medicine and biology. vol 39. issue 8. 2004-12-15. PMID:15551563. |
as dose rate is varied by changing fsd or depth (changing dose per pulse), detector current and dose rate are related by the expression i alpha ddelta where delta is approximately 0.98. |
2004-12-15 |
2023-08-12 |
Not clear |
| D P Lu, V Chandrakanthan, A Cahana, S Ishii, C O'Neil. Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre-implantation mouse embryo development. Journal of cell science. vol 117. issue Pt 8. 2004-12-10. PMID:15020683. |
the two-cell embryo expressed 1-o-phosphatidylinositol 3-kinase catalytic subunits p110 alpha, beta, gamma and delta, and regulatory subunits p85 alpha and beta. |
2004-12-10 |
2023-08-12 |
mouse |
| Nejmi Dilmac, Nathan Hilliard, Gregory H Hockerma. Molecular determinants of frequency dependence and Ca2+ potentiation of verapamil block in the pore region of Cav1.2. Molecular pharmacology. vol 66. issue 5. 2004-12-06. PMID:15286207. |
mutant and wild-type ca(v)1.2 channels were transiently expressed in tsa 201 cells with beta(1b) and alpha(2)delta subunits. |
2004-12-06 |
2023-08-12 |
Not clear |
| Alexandre Fredenrich, Paul A Grimald. Roles of peroxisome proliferator-activated receptor delta in skeletal muscle function and adaptation. Current opinion in clinical nutrition and metabolic care. vol 7. issue 4. 2004-12-02. PMID:15192438. |
the roles of peroxisome proliferator-activated receptor alpha and gamma isotypes have been well established, while the functions of the third member of the family, peroxisome proliferator-activated receptor delta, remained unclear until very recently. |
2004-12-02 |
2023-08-12 |
Not clear |