| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael R Tilley, Barbara Cagniard, Xiaoxi Zhuang, Dawn D Han, Narry Tiao, Howard H G. Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression. BMC neuroscience. vol 8. 2007-07-31. PMID:17584943. |
the dopamine transporter (dat) plays a critical role in regulating dopamine neurotransmission. |
2007-07-31 |
2023-08-12 |
mouse |
| Ming Chi Shih, Edson Amaro, Henrique Ballalai Ferraz, Marcelo Queiroz Hoexter, Fabricio Oliveira Goulart, Jairo Wagner, Li Fu Lin, Ying Kai Fu, Jair Jesus Mari, Acioly Luiz Tavares de Lacerda, Sergio Tufik, Rodrigo Affonseca Bressa. [Neuroimaging of the dopamine transporter in Parkinsons disease: first study using [99mTc]-TRODAT-1 and SPECT in Brazil]. Arquivos de neuro-psiquiatria. vol 64. issue 3A. 2007-07-30. PMID:17119808. |
dopamine transporter (dat) neuroimaging radiotracers were developed to estimate dopamine neuronal loss in vivo in parkinsons disease (pd). |
2007-07-30 |
2023-08-12 |
Not clear |
| Nicole L Bjorklund, Trent J Volz, James O Schen. Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters. European journal of pharmacology. vol 565. issue 1-3. 2007-07-26. PMID:17408612. |
recent literature has shown zn2+ inhibits dopamine transport by the dopamine transporter (dat), the main target of cocaine and some other drugs of abuse. |
2007-07-26 |
2023-08-12 |
human |
| Nicole L Bjorklund, Trent J Volz, James O Schen. Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters. European journal of pharmacology. vol 565. issue 1-3. 2007-07-26. PMID:17408612. |
cocaine inhibits dat and modulation of the dat by zn2+ may alter effects of cocaine on dopamine neurotransmission. |
2007-07-26 |
2023-08-12 |
human |
| Nicole L Bjorklund, Trent J Volz, James O Schen. Differential effects of Zn2+ on the kinetics and cocaine inhibition of dopamine transport by the human and rat dopamine transporters. European journal of pharmacology. vol 565. issue 1-3. 2007-07-26. PMID:17408612. |
in contrast, zn2+ did not alter transport by rat dat (rdat), with km and vmax values of 1.2+/-0.49 microm and 15.7+/-2.57 pmol/(sx10(6) cells), respectively, and removal of zn2+ did not increase dopamine transport values. |
2007-07-26 |
2023-08-12 |
human |
| Manuel Rodriguez, Sergio Gonzalez, Ingrid Morales, Magdalena Sabate, Tomas Gonzalez-Hernandez, Jose Luis Gonzalez-Mor. Nigrostriatal cell firing action on the dopamine transporter. The European journal of neuroscience. vol 25. issue 9. 2007-07-25. PMID:17561841. |
the influence of nigrostriatal cell firing on the dopamine transporter (dat) activity of the rat striatum was studied in vivo with amperometric methods. |
2007-07-25 |
2023-08-12 |
rat |
| Janice H Silva, Renato S Gomez, Paulo H C Diniz, Marcus V Gomez, Cristina Guatimosi. The effect of sevoflurane on the release of [3H]dopamine from rat brain cortical slices. Brain research bulletin. vol 72. issue 4-6. 2007-07-24. PMID:17452291. |
these data suggest that the dopamine release induced by sevoflurane is non-vesicular, independent of exocytosis and, would be mediated by the dopamine transporter (dat). |
2007-07-24 |
2023-08-12 |
rat |
| Janice H Silva, Renato S Gomez, Paulo H C Diniz, Marcus V Gomez, Cristina Guatimosi. The effect of sevoflurane on the release of [3H]dopamine from rat brain cortical slices. Brain research bulletin. vol 72. issue 4-6. 2007-07-24. PMID:17452291. |
gbr12909 and nomifensine, inhibitors of dat, decreased the release of [(3)h]dopamine evoked by sevoflurane. |
2007-07-24 |
2023-08-12 |
rat |
| Janice H Silva, Renato S Gomez, Paulo H C Diniz, Marcus V Gomez, Cristina Guatimosi. The effect of sevoflurane on the release of [3H]dopamine from rat brain cortical slices. Brain research bulletin. vol 72. issue 4-6. 2007-07-24. PMID:17452291. |
in conclusion, the present study suggests that sevoflurane increases [(3)h]dopamine release in brain cortical slices that is mediated by dat located at the plasma membrane. |
2007-07-24 |
2023-08-12 |
rat |
| Chaorui Huang, Chengke Tang, Andrew Feigin, Martin Lesser, Yilong Ma, Michael Pourfar, Vijay Dhawan, David Eidelber. Changes in network activity with the progression of Parkinson's disease. Brain : a journal of neurology. vol 130. issue Pt 7. 2007-07-24. PMID:17470495. |
at each timepoint the subjects also underwent pet imaging with [18f]-fluoropropyl betacit (fp-cit) to quantify longitudinal changes in caudate and putamen dopamine transporter (dat) binding. |
2007-07-24 |
2023-08-12 |
human |
| W Sihver, B Drewes, A Schulze, R A Olsson, H H Coene. Evaluation of novel tropane analogues in comparison with the binding characteristics of [18F]FP-CIT and [131I]beta-CIT. Nuclear medicine and biology. vol 34. issue 2. 2007-07-20. PMID:17307129. |
this study evaluated novel potential dopamine transporter (dat) inhibitors as ligands for positron emission tomography. |
2007-07-20 |
2023-08-12 |
rat |
| Andrew Newberg, Caryn Lerman, Nancy Wintering, Karl Ploessl, P David Mozle. Dopamine transporter binding in smokers and nonsmokers. Clinical nuclear medicine. vol 32. issue 6. 2007-07-19. PMID:17515751. |
this study determined whether healthy current smokers and nonsmokers exhibit differences in dopamine transporter (dat) binding measured by tc-99m trodat spect. |
2007-07-19 |
2023-08-12 |
Not clear |
| Ming Chi Shih, Luiz Augusto Franco de Andrade, Edson Amaro, Andre Carvalho Felicio, Henrique Ballalai Ferraz, Jairo Wagner, Marcelo Queiroz Hoexter, Li Fu Lin, Ying Kai Fu, Jair Jesus Mari, Sergio Tufik, Rodrigo Affonseca Bressa. Higher nigrostriatal dopamine neuron loss in early than late onset Parkinson's disease?--a [99mTc]-TRODAT-1 SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 6. 2007-07-12. PMID:17290452. |
the aim of this study was to compare dopamine neuronal loss in eopd with that of lopd with the same disease duration, through dopamine transporter (dat) estimation. |
2007-07-12 |
2023-08-12 |
Not clear |
| Nicolaas I Bohnen, Satyanarayana Gedela, Hiroto Kuwabara, Gregory M Constantine, Chester A Mathis, Stephanie A Studenski, Robert Y Moor. Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease. Journal of neurology. vol 254. issue 1. 2007-07-10. PMID:17508142. |
pd patients underwent (11)c-beta-cft dopamine transporter (dat) positron emission tomography (pet) imaging and clinical motor examination. |
2007-07-10 |
2023-08-12 |
human |
| L K McCallum, F Fernandez, S Quinlan, D P Macartney, R A Lea, L R Griffith. Association study of a functional variant in intron 8 of the dopamine transporter gene and migraine susceptibility. European journal of neurology. vol 14. issue 6. 2007-07-10. PMID:17539957. |
this study tested a functionally linked variable number tandem repeat (vntr) in intron 8 of the dopamine transporter gene (dat(int8)) in 550 migraine cases (401 with aura, 149 without aura) and 550 non-migraine controls. |
2007-07-10 |
2023-08-12 |
Not clear |
| L K McCallum, F Fernandez, S Quinlan, D P Macartney, R A Lea, L R Griffith. Association study of a functional variant in intron 8 of the dopamine transporter gene and migraine susceptibility. European journal of neurology. vol 14. issue 6. 2007-07-10. PMID:17539957. |
these findings offer no evidence for an association of the dat(int8) with migraine with and without aura and therefore do not implicate the dopamine transporter gene as a modifier of migraine risk. |
2007-07-10 |
2023-08-12 |
Not clear |
| M Huber, E Kirchler, M Karner, R Pych. Delusional parasitosis and the dopamine transporter. A new insight of etiology? Medical hypotheses. vol 68. issue 6. 2007-07-03. PMID:17134847. |
in the present paper we hypothesize for the first time a decreased striatal dopamine transporter (dat)-functioning (corresponding with an increased extracellular dopamine-level) as etiologic condition for dp (primary and secondary groups). |
2007-07-03 |
2023-08-12 |
human |
| M Huber, E Kirchler, M Karner, R Pych. Delusional parasitosis and the dopamine transporter. A new insight of etiology? Medical hypotheses. vol 68. issue 6. 2007-07-03. PMID:17134847. |
the dat as key regulator of the dopamine-reuptake in the human brain is well known (regulation of the extracellular dopamine concentration). |
2007-07-03 |
2023-08-12 |
human |
| A Dahlin, L Xia, W Kong, R Hevner, J Wan. Expression and immunolocalization of the plasma membrane monoamine transporter in the brain. Neuroscience. vol 146. issue 3. 2007-07-03. PMID:17408864. |
mpmat is co-expressed in many brain regions with the high affinity 5-ht transporter (sert) and the dopamine transporter (dat), but is also found in certain sites that receive monoamine innervation but lack significant expression of sert or dat. |
2007-07-03 |
2023-08-12 |
mouse |
| B F P Broekman, M Olff, F Boe. The genetic background to PTSD. Neuroscience and biobehavioral reviews. vol 31. issue 3. 2007-06-28. PMID:17126903. |
they have tested hypotheses involving key candidate genes in the serotonin (5-htt), dopamine (drd2, dat), glucocorticoid (gr), gaba (gabrb), apolipoprotein systems (apoe2), brain-derived neurotrophic factor (bdnf) and neuropeptide y (npy). |
2007-06-28 |
2023-08-12 |
Not clear |