| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven M Haffne. Pre-diabetes, insulin resistance, inflammation and CVD risk. Diabetes research and clinical practice. vol 61 Suppl 1. 2004-04-23. PMID:12880690. |
there is also accumulating evidence indicating that chronic sub-clinical inflammation as measured by such inflammatory markers as c-reactive protein (crp) is associated with insulin resistance and other features of the insulin resistance syndrome, increased risk of development of type 2 diabetes and increased cardiovascular event risk. |
2004-04-23 |
2023-08-12 |
Not clear |
| Adrian H Heald, Simon G Anderson, Fiona Ivison, Ian Laing, J Martin Gibson, Kennedy Cruickshan. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. vol 170. issue 1. 2004-04-23. PMID:12957685. |
inflammatory processes, marked in part by the acute phase reactant c-reactive protein (crp) and insulin resistance are implicated in atherogenesis. |
2004-04-23 |
2023-08-12 |
human |
| Adrian H Heald, Simon G Anderson, Fiona Ivison, Ian Laing, J Martin Gibson, Kennedy Cruickshan. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. vol 170. issue 1. 2004-04-23. PMID:12957685. |
we examined crp in ethnic groups with differing risk for cardiovascular disease and type 2 diabetes and its relationship with insulin sensitivity (homeostasis model assessment (homa)-s) and the igf system. |
2004-04-23 |
2023-08-12 |
human |
| Adrian H Heald, Simon G Anderson, Fiona Ivison, Ian Laing, J Martin Gibson, Kennedy Cruickshan. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. vol 170. issue 1. 2004-04-23. PMID:12957685. |
all underwent basic anthropometry, glucose tolerance testing and measurement of insulin sensitivity, crp and other metabolic variables. |
2004-04-23 |
2023-08-12 |
human |
| Adrian H Heald, Simon G Anderson, Fiona Ivison, Ian Laing, J Martin Gibson, Kennedy Cruickshan. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. vol 170. issue 1. 2004-04-23. PMID:12957685. |
in obese subjects insulin sensitivity was not associated with crp. |
2004-04-23 |
2023-08-12 |
human |
| Adrian H Heald, Simon G Anderson, Fiona Ivison, Ian Laing, J Martin Gibson, Kennedy Cruickshan. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. vol 170. issue 1. 2004-04-23. PMID:12957685. |
high crp (as a measure of chronic subclinical inflammation), low igf-i and low igfbp-1 are independently associated with the presence of the metabolic syndrome and with insulin resistance. |
2004-04-23 |
2023-08-12 |
human |
| Adrian H Heald, Simon G Anderson, Fiona Ivison, Ian Laing, J Martin Gibson, Kennedy Cruickshan. C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis. vol 170. issue 1. 2004-04-23. PMID:12957685. |
in obese subjects insulin sensitivity is not associated with changes in crp whilst in non-obese subjects crp independently contributes to variation in homa-s. |
2004-04-23 |
2023-08-12 |
human |
| Julia K Wegge, Christian K Roberts, Tung H Ngo, R James Barnar. Effect of diet and exercise intervention on inflammatory and adhesion molecules in postmenopausal women on hormone replacement therapy and at risk for coronary artery disease. Metabolism: clinical and experimental. vol 53. issue 3. 2004-04-09. PMID:15015151. |
in each subject, pre- and post-intervention fasting blood was drawn for serum lipid, insulin, glucose, c-reactive protein (crp), serum amyloid a (saa), interleukin-6 (il-6) and both soluble (s) intracellular and vascular adhesion molecule (sicam-1 and svcam-1) were measured. |
2004-04-09 |
2023-08-12 |
human |
| Julia K Wegge, Christian K Roberts, Tung H Ngo, R James Barnar. Effect of diet and exercise intervention on inflammatory and adhesion molecules in postmenopausal women on hormone replacement therapy and at risk for coronary artery disease. Metabolism: clinical and experimental. vol 53. issue 3. 2004-04-09. PMID:15015151. |
reductions in homeostasis model assessment for insulin resistance (homa-ir) (p <.01), crp (p <.01), saa (p <.01) and sicam-1 (p <.05) were noted, as well as an increase in the quantitative insulin sensitivity check index (p <.05). |
2004-04-09 |
2023-08-12 |
human |
| Luis Aldámiz-Echevarría, Pablo Sanjurjo, Alfredo Vallo, Mireia Aguirre, Gustavo Pérez-Nanclares, Pilar Gimeno, Miguel Rueda, José Ignacio Ruiz, Juan Rodríguez-Sorian. Genetic and metabolic determinants of increased plasma plasminogen activator inhibitor-1 activity in children with renal transplants. Pediatric nephrology (Berlin, Germany). vol 18. issue 8. 2004-04-06. PMID:12761670. |
in 29 children and adolescents with stable renal transplants, we related plasma pai-1 activity to an indicator of inflammatory status [plasma concentration of c-reactive protein (crp)] and to elements of the insulin resistance syndrome [body mass index (bmi), fasting insulinemia, homa index and plasma triglyceride, hdl-cholesterol, apolipoproteins a-1 and b concentrations]. |
2004-04-06 |
2023-08-12 |
Not clear |
| Daad Hassan Akba. Effect of metformin and sulfonylurea on C-reactive protein level in well-controlled type 2 diabetics with metabolic syndrome. Endocrine. vol 20. issue 3. 2003-12-12. PMID:12721499. |
the objective of this study was to examine the effect of the antihyperglycemic agents metformin (insulin sensitizer) and glibenclamide (insulin secretory agent) on the serum level of c-reactive protein (crp) in well-controlled type 2 diabetics with metabolic syndrome. |
2003-12-12 |
2023-08-12 |
human |
| b' Mario Romano, Maria Teresa Guagnano, Giovanni Pacini, Sergio Vigneri, Angela Falco, Marina Marinopiccoli, Maria Rosaria Manigrasso, Stefania Basili, Giovanni Dav\\xc3\\xa. Association of inflammation markers with impaired insulin sensitivity and coagulative activation in obese healthy women. The Journal of clinical endocrinology and metabolism. vol 88. issue 11. 2003-12-09. PMID:14602768.' |
impaired insulin sensitivity patients had significantly higher levels of c-reactive protein (crp), tgf-beta 1, plasminogen activator inhibitor-1 (pai-1), activated factor vii (viia), and prothrombin fragment 1 + 2 (f1 + 2) compared with either control subjects or nis patients. |
2003-12-09 |
2023-08-12 |
human |
| b' Mario Romano, Maria Teresa Guagnano, Giovanni Pacini, Sergio Vigneri, Angela Falco, Marina Marinopiccoli, Maria Rosaria Manigrasso, Stefania Basili, Giovanni Dav\\xc3\\xa. Association of inflammation markers with impaired insulin sensitivity and coagulative activation in obese healthy women. The Journal of clinical endocrinology and metabolism. vol 88. issue 11. 2003-12-09. PMID:14602768.' |
significant inverse correlations were observed between the insulin sensitivity index and tgf-beta 1, crp, pai-1, factor viia, and f1 + 2 levels. |
2003-12-09 |
2023-08-12 |
human |
| Laure Morin-Papunen, Katriina Rautio, Aimo Ruokonen, Pirjo Hedberg, Matti Puukka, Juha S Tapanaine. Metformin reduces serum C-reactive protein levels in women with polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism. vol 88. issue 10. 2003-11-12. PMID:14557435. |
low-grade chronic inflammation, reflected in elevated levels of serum c-reactive protein (crp), has recently been linked to obesity, insulin resistance syndromes such as polycystic ovary syndrome (pcos), and an increased risk of cardiovascular disease. |
2003-11-12 |
2023-08-12 |
human |
| Laure Morin-Papunen, Katriina Rautio, Aimo Ruokonen, Pirjo Hedberg, Matti Puukka, Juha S Tapanaine. Metformin reduces serum C-reactive protein levels in women with polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism. vol 88. issue 10. 2003-11-12. PMID:14557435. |
because the insulin sensitizer metformin has been shown to improve metabolic disturbances in pcos, it was of particular interest to examine serum crp levels during metformin therapy. |
2003-11-12 |
2023-08-12 |
human |
| Troels Krarup Hansen, Steffen Thiel, Søren Tang Knudsen, Claus Højbjerg Gravholt, Jens Sandahl Christiansen, Carl Erik Mogensen, Per Løgstrup Poulse. Elevated levels of mannan-binding lectin in patients with type 1 diabetes. The Journal of clinical endocrinology and metabolism. vol 88. issue 10. 2003-11-12. PMID:14557465. |
in diabetic subjects, crp levels correlated with poor glycemic control as indicated by hemoglobin a(1c) and daily insulin dose, which was not the case with mbl. |
2003-11-12 |
2023-08-12 |
human |
| Scott A Lear, Mustafa Toma, C Laird Birmingham, Jiri J Frohlic. Modification of the relationship between simple anthropometric indices and risk factors by ethnic background. Metabolism: clinical and experimental. vol 52. issue 10. 2003-11-06. PMID:14564681. |
apparently healthy men and women of european (n = 88) and south asian (n = 93) descent were recruited from 3 hospital communities and assessed for bmi, wc, waist-to-hip ratio (whr), blood pressure (bp), lipids, insulin, glucose, and crp. |
2003-11-06 |
2023-08-12 |
Not clear |
| Paul H Blac. The inflammatory response is an integral part of the stress response: Implications for atherosclerosis, insulin resistance, type II diabetes and metabolic syndrome X. Brain, behavior, and immunity. vol 17. issue 5. 2003-10-27. PMID:12946657. |
evidence is presented that the liver, the endothelium, and fat cell depots are the primary sources of cytokines, particularly il-6, and that il-6 and the acute phase protein (app), c-reactive protein (crp), are strongly associated with, and likely play a dominant role in, the development of this inflammatory process which leads to insulin resistance, non-insulin dependent diabetes mellitus type ii, and metabolic syndrome x. |
2003-10-27 |
2023-08-12 |
Not clear |
| Tsutomu Kazumi, Akira Kawaguchi, Tsutomu Hirano, Gen Yoshin. C-reactive protein in young, apparently healthy men: associations with serum leptin, QTc interval, and high-density lipoprotein-cholesterol. Metabolism: clinical and experimental. vol 52. issue 9. 2003-10-16. PMID:14506615. |
crp was also associated with resting heart rate (r = 0.14, p =.05), heart-rate corrected qt (qtc) interval (r = 0.22, p =.003) and several components of the insulin resistance (ir) syndrome. |
2003-10-16 |
2023-08-12 |
Not clear |
| Tsutomu Kazumi, Akira Kawaguchi, Tsutomu Hirano, Gen Yoshin. C-reactive protein in young, apparently healthy men: associations with serum leptin, QTc interval, and high-density lipoprotein-cholesterol. Metabolism: clinical and experimental. vol 52. issue 9. 2003-10-16. PMID:14506615. |
although crp was associated with fasting insulin (r = 0.15, p =.04), it was not related to serum adiponectin or ir index estimated using homeostasis model assessment (homa). |
2003-10-16 |
2023-08-12 |
Not clear |