| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saroj Niraula, Ryan J O Dowling, Marguerite Ennis, Martin C Chang, Susan J Done, Nicky Hood, Jaime Escallon, Wey Liang Leong, David R McCready, Michael Reedijk, Vuk Stambolic, Pamela J Goodwi. Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study. Breast cancer research and treatment. vol 135. issue 3. 2013-04-19. PMID:22933030. |
clinical (weight, symptoms, and quality of life) and blood [fasting serum insulin, glucose, homeostasis model assessment (homa), c-reactive protein (crp), and leptin] attributes were compared pre- and post-metformin as were terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) and ki67 scores (our primary endpoint) in tumor tissue. |
2013-04-19 |
2023-08-12 |
Not clear |
| Saroj Niraula, Ryan J O Dowling, Marguerite Ennis, Martin C Chang, Susan J Done, Nicky Hood, Jaime Escallon, Wey Liang Leong, David R McCready, Michael Reedijk, Vuk Stambolic, Pamela J Goodwi. Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study. Breast cancer research and treatment. vol 135. issue 3. 2013-04-19. PMID:22933030. |
body mass index (bmi) (-0.5 kg/m(2), p < 0.0001), weight (-1.2 kg, p < 0.0001), and homa (-0.21, p = 0.047) decreased significantly while non-significant decreases were seen in insulin (-4.7 pmol/l, p = 0.07), leptin (-1.3 ng/ml, p = 0.15) and crp (-0.2 mg/l, p = 0.35). |
2013-04-19 |
2023-08-12 |
Not clear |
| Keiji Tanigaki, Wanpen Vongpatanasin, Jose A Barrera, Dmitriy N Atochin, Paul L Huang, Ezio Bonvini, Philip W Shaul, Chieko Mine. C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery. Diabetes. vol 62. issue 3. 2013-04-17. PMID:23069625. |
elevations in c-reactive protein (crp) are associated with an increased risk of insulin resistance. |
2013-04-17 |
2023-08-12 |
mouse |
| Keiji Tanigaki, Wanpen Vongpatanasin, Jose A Barrera, Dmitriy N Atochin, Paul L Huang, Ezio Bonvini, Philip W Shaul, Chieko Mine. C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery. Diabetes. vol 62. issue 3. 2013-04-17. PMID:23069625. |
here we show that crp transgenic mice and wild-type mice administered recombinant crp are insulin resistant. |
2013-04-17 |
2023-08-12 |
mouse |
| Keiji Tanigaki, Wanpen Vongpatanasin, Jose A Barrera, Dmitriy N Atochin, Paul L Huang, Ezio Bonvini, Philip W Shaul, Chieko Mine. C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery. Diabetes. vol 62. issue 3. 2013-04-17. PMID:23069625. |
crp does not impair skeletal muscle glucose delivery in fcγriib(-/-) mice or in endothelial nitric oxide synthase knock-in mice with phosphomimetic modification of ser1176, which is normally phosphorylated by insulin signaling to stimulate nitric oxide-mediated skeletal muscle blood flow and glucose delivery and is dephosphorylated by crp/fcγriib. |
2013-04-17 |
2023-08-12 |
mouse |
| Keiji Tanigaki, Wanpen Vongpatanasin, Jose A Barrera, Dmitriy N Atochin, Paul L Huang, Ezio Bonvini, Philip W Shaul, Chieko Mine. C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery. Diabetes. vol 62. issue 3. 2013-04-17. PMID:23069625. |
thus, crp causes insulin resistance in mice through fcγriib-mediated inhibition of skeletal muscle glucose delivery. |
2013-04-17 |
2023-08-12 |
mouse |
| Morgan E Levine, Eileen M Crimmin. The impact of insulin resistance and inflammation on the association between sarcopenic obesity and physical functioning. Obesity (Silver Spring, Md.). vol 20. issue 10. 2013-03-19. PMID:22310233. |
the homeostasis model assessment (ir(homa)) was used to measure insulin resistance, while inflammatory state was assessed through measurement of serum c-reactive protein (crp). |
2013-03-19 |
2023-08-12 |
human |
| Lei Shi, Ming Li, Kenji Miyazawa, Yun Li, Masaru Hiramatsu, Jiayu Xu, Cai Gong, Xiaofan Jing, Fang He, Chengyu Huan. Effects of heat-inactivated Lactobacillus gasseri TMC0356 on metabolic characteristics and immunity of rats with the metabolic syndrome. The British journal of nutrition. vol 109. issue 2. 2013-03-19. PMID:22717016. |
organ coefficients, immune cell counts and serum insulin, adiponectin, c-reactive protein (crp), il-6, tnf-α, igg and secretory iga levels were measured at the 15th week after diet intervention. |
2013-03-19 |
2023-08-12 |
rat |
| Shaghayegh Haghjooy Javanmard, Mehdi Nematbakhsh, Azam Feghhi, Nasim Dan. Hyperinsulinemia may have a protective role in the early stages of atherosclerosis in rabbit model of hypercholesterolemia. Journal of diabetes and metabolic disorders. vol 11. issue 1. 2013-03-19. PMID:23497719. |
we examined alteration of plasma levels of insulin, c-reactive protein (crp) and total no metabolites (nox), as well as fatty streak formation in the rabbit model of hypercholesterolemia. |
2013-03-19 |
2023-08-12 |
rabbit |
| Mehmet Kanbay, Mahmut Ilker Yilmaz, Mugurel Apetrii, Mutlu Saglam, Halil Yaman, Hilmi Umut Unal, Mahmut Gok, Kayser Caglar, Yusuf Oguz, Mujdat Yenicesu, Hakki Cetinkaya, Tayfun Eyileten, Cengizhan Acikel, Abdulgaffar Vural, Adrian Covi. Relationship between serum magnesium levels and cardiovascular events in chronic kidney disease patients. American journal of nephrology. vol 36. issue 3. 2013-03-12. PMID:22948239. |
to date, no group has evaluated magnesium as a cardiovascular risk factor in chronic kidney disease (ckd) subjects, in which closely interrelated factors and potential confounders such as endothelial dysfunction, insulin resistance (the homeostasis model assessment (homa) index) and inflammation (expressed as serum c-reactive protein (crp) levels) were also considered. |
2013-03-12 |
2023-08-12 |
human |
| Xiaoshun Qian, Tong Yin, Tianzhi Li, Chunyan Kang, Ruibiao Guo, Baojun Sun, Changting Li. High levels of inflammation and insulin resistance in obstructive sleep apnea patients with hypertension. Inflammation. vol 35. issue 4. 2013-01-30. PMID:22527145. |
osa patients (apnea hyponea index, ahi ≥ 40/h, n = 70) were examined by polysomnography and blood analysis for the measurements of fasting plasma glucose, serum insulin (fins), high-sensitivity c-reactive protein (crp), peptide c,tnf-α, il-6, and il-10. |
2013-01-30 |
2023-08-12 |
Not clear |
| Claudia Luévano-Contreras, Ma Eugenia Garay-Sevilla, Kazimierz Wrobel, Juan M Malacara, Katarzyna Wrobe. Dietary advanced glycation end products restriction diminishes inflammation markers and oxidative stress in patients with type 2 diabetes mellitus. Journal of clinical biochemistry and nutrition. vol 52. issue 1. 2013-01-24. PMID:23341693. |
the objective of the present study is to investigate the effect of dages restriction on tumor necrosis factor-α (tnf-α), malondialdehyde, c-reactive protein (crp), and insulin resistance in dm2 patients. |
2013-01-24 |
2023-08-12 |
human |
| Claudia Luévano-Contreras, Ma Eugenia Garay-Sevilla, Kazimierz Wrobel, Juan M Malacara, Katarzyna Wrobe. Dietary advanced glycation end products restriction diminishes inflammation markers and oxidative stress in patients with type 2 diabetes mellitus. Journal of clinical biochemistry and nutrition. vol 52. issue 1. 2013-01-24. PMID:23341693. |
at the beginning and the end of study, we collected anthropometric measurements, and values of circulating glucose, hba1c, lipids, insulin, serum ages, crp, tnf-α and malondialdehyde. |
2013-01-24 |
2023-08-12 |
human |
| Amparo Vayá, Leonor Rivera, Antonio Hernández-Mijares, Miguel de la Fuente, Eva Solá, Marco Romagnoli, R Alis, Begoña Lai. Homocysteine levels in morbidly obese patients: its association with waist circumference and insulin resistance. Clinical hemorheology and microcirculation. vol 52. issue 1. 2013-01-07. PMID:22460264. |
moreover, morbidly obese subjects showed higher waist circumference, glucose, insulin, homa, leptin, triglycerides, fibrinogen, c reactive protein (crp) (p < 0.001, respectively), and lower vitamin b12 (p = 0.002), folic acid and hdl-cholesterol (p < 0.001, respectively). |
2013-01-07 |
2023-08-12 |
human |
| Maria F Faienza, Annamaria Ventura, Rosaria Lauciello, Antonino Crinò, Letizia Ragusa, Luciano Cavallo, Sabrina Spera, Graziano Grugn. Analysis of endothelial protein C receptor gene and metabolic profile in Prader-Willi syndrome and obese subjects. Obesity (Silver Spring, Md.). vol 20. issue 9. 2013-01-02. PMID:22193922. |
furthermore, we evaluated crp levels, glucose, insulin, and lipid profile, and we found higher crp values in pws adults with respect to children with pws and controls, and a better insulin sensitivity in all pws subjects than in the controls. |
2013-01-02 |
2023-08-12 |
human |
| M F Suárez-Ortegón, A Arbeláez, M Mosquera, F Méndez, C Aguilar-de Plat. C-reactive protein, waist circumference, and family history of heart attack are independent predictors of body iron stores in apparently healthy premenopausal women. Biological trace element research. vol 148. issue 2. 2012-12-31. PMID:22328310. |
data were collected through procedures of anthropometric measurements, questionnaires for personal/familial antecedents, and dietary intake (24-h recall), and biochemical determinations (ferritin, c reactive protein (crp), glucose, insulin, and lipid profile) in blood serum samples obtained. |
2012-12-31 |
2023-08-12 |
Not clear |
| Nikolaos P E Kadoglou, Nikolaos Sailer, Alkistis Kapelouzou, Stylianos Lampropoulos, Ioulia Vitta, Alkiviadis Kostakis, Christos D Liapi. Effects of atorvastatin on apelin, visfatin (nampt), ghrelin and early carotid atherosclerosis in patients with type 2 diabetes. Acta diabetologica. vol 49. issue 4. 2012-12-03. PMID:21748474. |
anthropometric parameters, blood pressure, glycemic and lipid profile, high-sensitivity crp (hscrp), insulin resistance (homa-ir), apelin, visfatin and ghrelin were measured at baseline and after 12 months. |
2012-12-03 |
2023-08-12 |
human |
| Sophie Stoppa-Vaucher, Mirjam A Dirlewanger, Christoph A Meier, Philippe de Moerloose, Guido Reber, Pascale Roux-Lombard, Christoph Combescure, Sonja Saudan, Valerie M Schwitzgebe. Inflammatory and prothrombotic states in obese children of European descent. Obesity (Silver Spring, Md.). vol 20. issue 8. 2012-11-29. PMID:22484367. |
fasting glucose level, insulin, prothrombin time (pt), fibrinogen, activated partial thromboplastin time (aptt), d-dimer, endogenous thrombin potential (etp), c-reactive protein (crp), interleukin-6 (il-6), interleukin-10 (il-10), interferon-γ-inducible-protein (ip-10), monocyte chemoattractant protein 1 (mcp-1), and interleukin-1 receptor antagonist (il-1ra) were measured. |
2012-11-29 |
2023-08-12 |
human |
| Guoyue Yuan, Jue Jia, Liangliang Di, Libin Zhou, Sijing Dong, Jingjing Ye, Dong Wang, Ling Yang, Jifang Wang, Lianxi Li, Ying Yang, Chaoming Mao, Mingdao Che. Effects of C-reactive protein on adipokines genes expression in 3T3-L1 adipocytes. Biochemical and biophysical research communications. vol 424. issue 3. 2012-11-19. PMID:22771801. |
these results collectively suggest that crp regulates adiponectin, tnf-α, leptin, il-6 and ppar-γ genes expression, and that might represent a mechanism by which crp regulates insulin resistance, obesity and metabolic syndrome. |
2012-11-19 |
2023-08-12 |
Not clear |
| Eitan Amir, Reena S Cecchini, Patricia A Ganz, Joseph P Costantino, Samantha Beddows, Nicola Hood, Pamela J Goodwi. 25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1. Breast cancer research and treatment. vol 133. issue 3. 2012-11-06. PMID:22415479. |
fasting serum banked at trial enrolment was assayed for 25-hydroxy vitamin-d (25ohd), insulin, leptin (adipocytokine), and c-reactive protein (crp, marker of inflammation). |
2012-11-06 |
2023-08-12 |
human |