| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isaac Subirana, Montserrat Fitó, Oscar Diaz, Joan Vila, Albert Francés, Eva Delpon, Juan Sanchis, Roberto Elosua, Daniel Muñoz-Aguayo, Irene R Dégano, Jaume Marruga. Prediction of coronary disease incidence by biomarkers of inflammation, oxidation, and metabolism. Scientific reports. vol 8. issue 1. 2019-09-09. PMID:29453342. |
this study aimed to determine the relationship with cad and the predictive capacity of nine biomarkers of inflammation (tnf-α, il-10, il-6, mcp-1, crp), oxidation (ghs-px), and metabolism (adiponectin, leptin, and insulin). |
2019-09-09 |
2023-08-13 |
human |
| Michael V Fedewa, Elizabeth D Hathaway, Simon Higgins, Ronald L Forehand, Michael D Schmidt, Ellen M Evan. Moderate, but not vigorous, intensity exercise training reduces C-reactive protein. Acta cardiologica. vol 73. issue 3. 2019-08-19. PMID:28847205. |
the purpose of this investigation was to determine the relative efficacy of six weeks of moderate-intensity cycling (mod-c) and vigorous sprint-interval cycling (vig-sic) on lipid profile, insulin (ins) and insulin resistance using the homeostatic model assessment (homa-ir) and c-reactive protein (crp) in inactive, overweight/obese (ow/ob) young women. |
2019-08-19 |
2023-08-13 |
Not clear |
| Lin-Qin Ma, Jing-Chun Zhang, Yue Liu, Yu Qiao, Xin-Li Sun, Shu-Yan Lei, Qiao-Xian Zheng, Ting Ma. [Intervention effects and mechanism of Chinese herbal medicine of supplementing Qi and activating blood circulation on chronic intermittent hypoxia composite insulin resistance ApoE~(-/-) mice model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 1. 2019-08-06. PMID:30868825. |
this study aims to observe the intervention effects of chinese herbal medicine of supplementing qi and activating blood circulation on chronic intermittent hypoxia(cih) composite insulin resistance(ir) mediated atherosclerosis(as) mice model,and to observe the mechanism of srebp-1 c signaling molecule.ir apo e-/-mice model was induced by high-fat diet combined with stz injection.then the mice were treated with hypoxic animal incubator for 8 h per day and 8 weeks to establish a cih+ir-apoe-/-mouse model.model mice were randomly and averagely divided into normoxic control group(nc),model group(cih) and srebps inhibitor group(betulin),atorvastatin group(wm),tcm low-dose group(tcm-l),tcm middle-dose group(tcm-m) and tcm high-dose group(tcm-h) group.chinese herbal medicine of supplementing qi and activating blood circulation including ginsenosides combined with ligustrazine(tmp) were used as intervention drugs.the study observed the effect of drugs on ir,serum lipid,inflammation,stress,as and srebp-1 c related molecules.the results showed that fasting blood glucose in tcm-h group decreased compared with other experimental groups(p<0.05).hdl-c level in betulin group,wm group,tcm-h group was higher than that in cih group(p<0.05).ldl-c level in tcm-m group,tcm-h group is lower than that in cih group(p<0.05).the level of crp in cih group was higher than that in other groups(p<0.05).the level of sod in tcm-h group was higher than that in cih group(p<0.05).nc group and cih group showed obvious as aortic plaque,while betulin group,wm group,tcm-h group showed reduction in as plaque(p<0.05).for descending aorta,as plaque in cih group was multiple and large,while less and smaller in wm group and tcm-h(p<0.05).the expression of srebp-1 c and fas in aorta and skeletal muscle in tcm-h group was lower than that in cih group(p<0.05).in aorta,the expression of tnf-α and cd106(vcam-1) was lower in tcm-h group than that in cih group(p<0.05).in aorta,skeletal muscle and liver,the level of p-irs-1 in tcm-h group was significantly higher than that in cih group(p<0.05).in aorta and liver,the expression of hif-1α in tcm-h group was lower than that in cih group(p<0.05).the study demonstrated that combination ginsenosides with tmp could improve ir and serum lipid level and inhibit inflammation and oxidative stress as well as ultimately alleviate as to some extent.and the mechanism of its interventional effects might be related to the inhibition of cih-induced upregulation of srebp-1 c related molecules. |
2019-08-06 |
2023-08-13 |
mouse |
| Daniel Antonio de Luis Román, David Primo, Rocio Aller, Olatz Izaol. Association of the rs10830963 polymorphism in MTNR1B with fasting glucose, serum adipokine levels and components of metabolic syndrome in adult obese subjects. Nutricion hospitalaria. vol 36. issue 1. 2019-07-05. PMID:30834760. |
measurements of anthropometric parameters, blood pressure, fasting blood glucose, c-reactive protein (crp), insulin concentration, insulin resistance (homa-ir), homa-b, lipid profi le and adipocytokines levels were performed. |
2019-07-05 |
2023-08-13 |
human |
| M Bellan, S Bor, A Gibbin, A Gualerzi, S Favretto, G Guaschino, R Bonometti, A Rossini, D Sola, R Pedrazzoli, G P Carnevale Schianca, M Pirisi, P P Sainagh. Inflammatory markers predict insulin sensitivity in active rheumatoid arthritis but not in psoriatic arthritis. Reumatismo. vol 70. issue 4. 2019-07-03. PMID:30570241. |
moreover, c-reactive protein (crp) levels were associated with plasma glucose and insulin levels measured 120 min after the glucose load (β=0.91, p=0.0003 and β=0.77, p=0.0006, respectively); isi and eisi were predicted by crp (β=-0.79, p=0.0006; β=-0.80, p=0.0001, respectively). |
2019-07-03 |
2023-08-13 |
Not clear |
| Trevor Teich, Jacklyn A Pivovarov, Deanna P Porras, Emily C Dunford, Michael C Riddel. Curcumin limits weight gain, adipose tissue growth, and glucose intolerance following the cessation of exercise and caloric restriction in rats. Journal of applied physiology (Bethesda, Md. : 1985). vol 123. issue 6. 2019-06-20. PMID:28839007. |
insulin area under the curve (auc) during an oral glucose tolerance test, homa-ir, and c-reactive protein (crp) were elevated 6-, 9-, and 2-fold, respectively, in the detrained + placebo group vs. the trained group (all p < 0.05). |
2019-06-20 |
2023-08-13 |
rat |
| Trevor Teich, Jacklyn A Pivovarov, Deanna P Porras, Emily C Dunford, Michael C Riddel. Curcumin limits weight gain, adipose tissue growth, and glucose intolerance following the cessation of exercise and caloric restriction in rats. Journal of applied physiology (Bethesda, Md. : 1985). vol 123. issue 6. 2019-06-20. PMID:28839007. |
curcumin reduced insulin auc, homa-ir, and crp vs. the placebo group (all p < 0.05). |
2019-06-20 |
2023-08-13 |
rat |
| Behzad Mesbahzadeh, Seyed Ali Rajaei, Parnia Tarahomi, Seyed Ali Seyedinia, Mehrnoush Rahmani, Fatemeh Rezamohamadi, Muhammad Azam Kakar, Nasroallah Moradi-Ko. Beneficial effects of Spirogyra Neglecta Extract on antioxidant and anti-inflammatory factors in streptozotocin-induced diabetic rats. Biomolecular concepts. vol 9. issue 1. 2019-06-05. PMID:30660132. |
at the end of the trial, the serum concentrations of glucose, interleukin-6 (il-6), tumor necrosis factor-a (tnf-a), malondialdehyde (mda), glutathione (gsh), total antioxidant status (tas), c-reactive protein (crp), insulin, triglycerides, and cholesterol were examined by specified procedures. |
2019-06-05 |
2023-08-13 |
rat |
| Seyed Hamid Borsi, Homeira Rashidi, Maryam Shaabanpour, Hanieh Raj. The effects of inhaled corticosteroid on insulin sensitivity in asthmatic patients. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace. vol 88. issue 1. 2019-05-20. PMID:29557573. |
spirometry, fasting blood sugar (fbs), blood sugar 2 hour post prandial (bs2hpp), hba1c, low density lipoprotein (ldl), high density lipoprotein (hdl), insulin level, and c reactive protein (crp) were measured. |
2019-05-20 |
2023-08-13 |
Not clear |
| Helal F Hetta, Manal E Ez-Eldeen, Ghada A Mohamed, Marwa A Gaber, Hala M ElBadre, Esraa A Ahmed, Rasha B Abdellatief, Rehab M Abd-ElBaky, Azza Elkady, Amany M Nafee, Asmaa M Zahran, Mohammad Ahma. Visfatin Serum Levels in Obese Type 2 Diabetic Patients: Relation to Proinflammatory Cytokines and Insulin Resistance. The Egyptian journal of immunology. vol 25. issue 2. 2019-05-15. PMID:30600957. |
also there was a strong positive correlation between serum level of visfatin, il6, tnf- and crp and some anthropometric characteristics including (wc,bmi and insulin resistance). |
2019-05-15 |
2023-08-13 |
Not clear |
| Hussein A Khambalia, M Yvonne Alexander, Mahesan Nirmalan, Ria Weston, Phillip Pemberton, Zia Moinuddin, Angela Summers, David van Dellen, Titus Augustin. Links between a biomarker profile, cold ischaemic time and clinical outcome following simultaneous pancreas and kidney transplantation. Cytokine. vol 105. 2019-04-29. PMID:29428804. |
serum was measured within the first 72 h post-spkt for pro- and anti-inflammatory cytokines (il -6, -10 and tnf-α), inflammatory markers (wcc and crp) and endocrine markers (insulin, c-peptide, glucagon and resistin). |
2019-04-29 |
2023-08-13 |
Not clear |
| Jamie N Justice, Luigi Ferrucci, Anne B Newman, Vanita R Aroda, Judy L Bahnson, Jasmin Divers, Mark A Espeland, Santica Marcovina, Michael N Pollak, Stephen B Kritchevsky, Nir Barzilai, George A Kuche. A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup. GeroScience. vol 40. issue 5-6. 2019-04-26. PMID:30151729. |
application of these selection criteria to the current literature resulted in a short list of blood-based biomarkers proposed for tame: il-6, tnfα-receptor i or ii, crp, gdf15, insulin, igf1, cystatin c, nt-probnp, and hemoglobin a1c. |
2019-04-26 |
2023-08-13 |
human |
| R Tabassum, A R Mia, K M Reza-Ul-Haq, M Yesmin, J M Faruqu. C-reactive Protein Level in Type-2 Diabetic Patients Attending Mymensingh Medical College Hospital, Mymensingh. Mymensingh medical journal : MMJ. vol 26. issue 1. 2019-04-15. PMID:28260756. |
c-reactive protein (crp) is a sensitive physiological biomarker of sub-clinical inflammation associated with hyperglycemia, insulin resistance and type 2 diabetic patients. |
2019-04-15 |
2023-08-13 |
human |
| Jiang Zhang, Yunxia Wu, Zhiqiang Ga. Correlations of C-Reactive Protein (CRP), Interleukin-6 (IL-6), and Insulin Resistance with Cerebral Infarction in Hypertensive Patients. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-04-10. PMID:30804318. |
correlations of c-reactive protein (crp), interleukin-6 (il-6), and insulin resistance with cerebral infarction in hypertensive patients. |
2019-04-10 |
2023-08-13 |
Not clear |
| Jiang Zhang, Yunxia Wu, Zhiqiang Ga. Correlations of C-Reactive Protein (CRP), Interleukin-6 (IL-6), and Insulin Resistance with Cerebral Infarction in Hypertensive Patients. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-04-10. PMID:30804318. |
background the aim of this study was to investigate the correlations of c-reactive protein (crp), interleukin-6 (il-6), and insulin resistance (ir) with cerebral infarction in hypertensive patients. |
2019-04-10 |
2023-08-13 |
Not clear |
| Sílvia Xargay-Torrent, Gemma Carreras-Badosa, Sara Borrat-Padrosa, Anna Prats-Puig, Pilar Soriano, Elena Álvarez-Castaño, Mª Jose Ferri, Francis De Zegher, Lourdes Ibáñez, Abel López-Bermejo, Judit Bassol. Circulating sex hormone binding globulin: An integrating biomarker for an adverse cardio-metabolic profile in obese pregnant women. PloS one. vol 13. issue 10. 2019-04-04. PMID:30321217. |
cardio-metabolic [c-reactive protein (crp), blood pressure (bp), glycosylated hemoglobin (hbac1), glucose, c-peptide, insulin, triglycerides and high molecular weight (hmw) adiponectin], and endocrine [testosterone and estradiol] parameters were also assessed. |
2019-04-04 |
2023-08-13 |
Not clear |
| Zahava Solomon, Yafit Levin, Einor Ben Assayag, Orit Furman, Shani Shenhar-Tsarfaty, Shlomo Berliner, Avi Ohr. The Implication of Combat Stress and PTSD Trajectories in Metabolic Syndrome and Elevated C-Reactive Protein Levels: A Longitudinal Study. The Journal of clinical psychiatry. vol 78. issue 9. 2019-04-03. PMID:28994516. |
the present study prospectively assessed the following over 23 years: (1) the association of psychological and physiologic stress during captivity with elevated c-reactive protein (crp) levels and metabolic syndrome (mets), which includes hypertension; elevated levels of insulin, triglycerides, and fasting glucose; decreased levels of high-density lipoprotein cholesterol; and obesity and (2) the implication of ptsd trajectories in elevated crp levels and mets. |
2019-04-03 |
2023-08-13 |
Not clear |
| Mohamed A Haidara, Mohammad Dallak, Abbas O El Karib, Mohamed Abd Ellatif, Refaat A Eid, El Hassan A Heidar, Bahjat Al-An. Insulin protects against hepatocyte ultrastructural damage induced by type 1 diabetes mellitus in rats. Ultrastructural pathology. vol 42. issue 6. 2019-03-20. PMID:30497321. |
in addition, the blood chemistry profile complements the tem data as demonstrated by an increase in serum levels of alanine aminotransferase (alt), dyslipidemia, c-reactive protein (crp), tumor necrosis factor-alpha (tnf-α), interleukin-6 (il-6), and malondialdehyde (mda) by t1dm that were significantly (p < 0.05) reduced with insulin injections. |
2019-03-20 |
2023-08-13 |
rat |
| Calum D Moulton, Christopher W P Hopkins, Khalida Ismail, Daniel Stah. Repositioning of diabetes treatments for depressive symptoms: A systematic review and meta-analysis of clinical trials. Psychoneuroendocrinology. vol 94. 2019-03-15. PMID:29775878. |
data were also collected on insulin resistance (homa-ir), c-reactive protein (crp) and fasting blood glucose (fbg) as correlates of response. |
2019-03-15 |
2023-08-13 |
Not clear |
| Wayne Huey-Herng Sheu, Wen-Chang Wang, Kwan-Dun Wu, Chih-Tsueng He, Chii-Min Hwu, Thomas Quertermous, Wan-Shan Hsieh, Wen-Jane Lee, Chih-Tai Ting, Yii-Der I Chen, Chao A Hsiun. CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study. Scientific reports. vol 7. issue 1. 2019-03-14. PMID:28801571. |
we conducted a cross-sectional study consisting of 945 siblings from 330 families collected by the stanford asian pacific program in hypertension and insulin resistance (sapphire) to investigate associations between crp polymorphisms, circulating crp, diabetes, and glucose levels. |
2019-03-14 |
2023-08-13 |
Not clear |